ATE449781T1 - Nucleinsäure enthaltender polymerisierbarer komplex - Google Patents

Nucleinsäure enthaltender polymerisierbarer komplex

Info

Publication number
ATE449781T1
ATE449781T1 AT98910016T AT98910016T ATE449781T1 AT E449781 T1 ATE449781 T1 AT E449781T1 AT 98910016 T AT98910016 T AT 98910016T AT 98910016 T AT98910016 T AT 98910016T AT E449781 T1 ATE449781 T1 AT E449781T1
Authority
AT
Austria
Prior art keywords
complex containing
nucleic acid
polymerizable
polymerized layer
polymerizable complex
Prior art date
Application number
AT98910016T
Other languages
English (en)
Inventor
T Boles
Stephen Kron
Christopher Adams
Original Assignee
Matrix Technologies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matrix Technologies Llc filed Critical Matrix Technologies Llc
Application granted granted Critical
Publication of ATE449781T1 publication Critical patent/ATE449781T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AT98910016T 1997-03-05 1998-02-20 Nucleinsäure enthaltender polymerisierbarer komplex ATE449781T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/812,105 US5932711A (en) 1997-03-05 1997-03-05 Nucleic acid-containing polymerizable complex
PCT/US1998/003246 WO1998039351A1 (en) 1997-03-05 1998-02-20 Nucleic acid-containing polymerizable complex

Publications (1)

Publication Number Publication Date
ATE449781T1 true ATE449781T1 (de) 2009-12-15

Family

ID=25208519

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98910016T ATE449781T1 (de) 1997-03-05 1998-02-20 Nucleinsäure enthaltender polymerisierbarer komplex

Country Status (8)

Country Link
US (2) US5932711A (de)
EP (1) EP0971943B1 (de)
JP (1) JP2001513109A (de)
AT (1) ATE449781T1 (de)
AU (1) AU6436498A (de)
CA (1) CA2283798A1 (de)
DE (1) DE69841304D1 (de)
WO (1) WO1998039351A1 (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852487B1 (en) 1996-02-09 2005-02-08 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
US20020150921A1 (en) * 1996-02-09 2002-10-17 Francis Barany Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
EP1736554B1 (de) * 1996-05-29 2013-10-09 Cornell Research Foundation, Inc. Bestimmung von Unterschieden in der Nukleinsäuresequenz mittels einer Kombination von Ligasebestimmung und Polymerasekettenreaktion
WO1998051823A1 (en) * 1997-05-16 1998-11-19 Mosaic Technologies Electrophoretic analysis of molecules using immobilized probes
WO1999066078A1 (en) 1998-06-18 1999-12-23 Mosaic Technologies Denaturing gradient affinity electrophoresis and methods of use thereof
WO1999066079A1 (en) * 1998-06-19 1999-12-23 Mosaic Technologies Detection of non-viral organisms with srp rna
WO2000020643A1 (en) * 1998-10-05 2000-04-13 Mosaic Technologies Reverse displacement assay for detection of nucleic acid sequences
WO2000029619A2 (en) * 1998-11-13 2000-05-25 Mosaic Technologies Multielement analytical device for assay of nucleic acid sequences and uses therefore
EP1155056A4 (de) * 1998-12-04 2004-05-12 Mosaic Technologies Inc Verfahren zur immobilisierung von oligonucleotiden
US20050153926A1 (en) * 1998-12-04 2005-07-14 Adams Christopher P. Method for the immobilization of oligonucleotides
US6441152B1 (en) 1998-12-08 2002-08-27 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
WO2000050870A1 (en) * 1999-02-26 2000-08-31 Mosaic Technologies Biochemical purification devices with immobilized capture probes and their uses
AU4053900A (en) * 1999-04-02 2000-10-23 Exact Sciences Corporation Electrophoretic analysis of target molecules using adapter molecules
US6372813B1 (en) 1999-06-25 2002-04-16 Motorola Methods and compositions for attachment of biomolecules to solid supports, hydrogels, and hydrogel arrays
US6664061B2 (en) 1999-06-25 2003-12-16 Amersham Biosciences Ab Use and evaluation of a [2+2] photoaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix
US6921638B2 (en) * 1999-06-25 2005-07-26 Amersham Biosciences Ab Hydrogel-based microarray signal amplification methods and devices therefor
WO2001002452A1 (en) 1999-07-02 2001-01-11 Symyx Technologies, Inc. Polymer brushes for immobilizing molecules to a surface or substrate, where the polymers have water-soluble or water-dispersible segments and probes bonded thereto
EP1208238B1 (de) 1999-08-27 2008-11-12 Matrix Technologies Corporation Verfahren zur Immobilisierung von Oligonukleotiden auf festem Trägermaterial
US6376177B1 (en) * 1999-10-06 2002-04-23 Virtual Pro, Inc. Apparatus and method for the analysis of nucleic acids hybridization on high density NA chips
US7109024B2 (en) * 1999-11-15 2006-09-19 Dr. Chip Biotechnology Inc. Biomolecule-bound substrates
US20030138774A1 (en) * 2000-01-19 2003-07-24 Jones Chris L. Methods and apparatus for separating and detecting nucleic acid
EP1130121A3 (de) * 2000-01-26 2003-04-16 Nisshinbo Industries Inc. Immobilisierte Nukleinsäuren und Methoden zum Nchhweis von Nukleinsäuren
US20040014644A1 (en) * 2000-03-14 2004-01-22 Vladimir Efimov Oligonucleotide analogues and methods of use for modulating gene expression
US6962906B2 (en) * 2000-03-14 2005-11-08 Active Motif Oligonucleotide analogues, methods of synthesis and methods of use
EP1263773A4 (de) 2000-03-14 2005-08-31 Active Motif Analoge von oligonukleotiden, methoden der synthese und methoden der verwendung
WO2001079548A2 (en) 2000-04-14 2001-10-25 Cornell Research Foundation, Inc. Method of designing addressable array for detection of nucleic acid sequence differences using ligase detection reaction
RU2278612C2 (ru) * 2000-07-14 2006-06-27 Лайфскен, Инк. Иммуносенсор
DE10049074A1 (de) * 2000-10-02 2002-04-18 Andreas Kage Verfahren zur Selektion hochaffin an ein Target bindender Nukleinsäuren
WO2002056021A2 (en) * 2001-01-10 2002-07-18 Symyx Technologies Inc Polymer brushes for immobilizing molecules to a surface
US20020142304A1 (en) * 2001-03-09 2002-10-03 Anderson Daniel G. Uses and methods of making microarrays of polymeric biomaterials
US20020175317A1 (en) * 2001-05-24 2002-11-28 Lee Jeremy Stuart Nucleic acid circuit elements and methods
US20050261486A1 (en) * 2001-05-31 2005-11-24 Q-Rna Compositions and methods for binding agglomeration proteins
US20040005543A1 (en) * 2002-01-18 2004-01-08 Abraham Grossman Compositions and methods for binding agglomeration proteins
US6656725B2 (en) * 2001-08-15 2003-12-02 The University Of Chicago Method of fabrication of microarray of gel-immobilized compounds on a chip by copolymerization
US7846656B2 (en) * 2001-10-16 2010-12-07 Institut Molekulyarnoi Biologii Im.V.A. Engelgardta Rossiiskoi Akademii Nauk Composition for polymerizing immobilization of biological molecules and method for producing said composition
JP3888947B2 (ja) * 2002-02-01 2007-03-07 日清紡績株式会社 生体分子の担体への固定法
US20030180814A1 (en) * 2002-03-21 2003-09-25 Alastair Hodges Direct immunosensor assay
US20060134713A1 (en) 2002-03-21 2006-06-22 Lifescan, Inc. Biosensor apparatus and methods of use
US20040028804A1 (en) * 2002-08-07 2004-02-12 Anderson Daniel G. Production of polymeric microarrays
JP2005534942A (ja) * 2002-08-08 2005-11-17 シーメンス　アクチエンゲゼルシヤフト バイオセンサーテクノロジーのためのポリアクリルアミドをベースとするヒドロゲルからなる認識層
EP1567569B1 (de) 2002-11-29 2008-07-23 Marcella Chiari Verfahren zur immobilisierung biologischer moleküle an feste oberflächen
US20040248162A1 (en) * 2002-12-17 2004-12-09 Affymetrix, Inc. Releasable polymer arrays
US20040185473A1 (en) * 2002-12-17 2004-09-23 Affymetrix, Inc. Releasable polymer arrays
DE10323685A1 (de) * 2003-05-22 2004-12-09 Rühe, Jürgen, Prof. Dr. Verfahren zur kovalenten Immobilisierung von Sonden-Biomolekülen an organischen Oberflächen
US7785769B2 (en) * 2003-07-25 2010-08-31 The United States of America as reprsented by the Secretary of the Navy Immobilization of oligonucleotides and proteins in sugar-containing hydrogels
US20050136536A1 (en) * 2003-09-15 2005-06-23 Anderson Daniel G. Embryonic epithelial cells
AU2004274021B2 (en) * 2003-09-18 2009-08-13 Isis Pharmaceuticals, Inc. 4'-thionucleosides and oligomeric compounds
JP2007512509A (ja) * 2003-11-05 2007-05-17 エグザクト サイエンシーズ コーポレイション 反復的親和性分離およびその使用
CA2494571C (en) * 2003-12-02 2010-02-09 F.Hoffmann-La Roche Ag Oligonucleotides containing molecular rods
DE102004062281A1 (de) * 2003-12-29 2005-07-28 Siemens Ag Verfahren und Spotting-Lösung zum Herstellen von Microarrays
EP1701785A1 (de) 2004-01-07 2006-09-20 Solexa Ltd. Modifizierte molekülarrays
US7547775B2 (en) * 2004-12-31 2009-06-16 Affymetrix, Inc. Parallel preparation of high fidelity probes in an array format
US7749701B2 (en) * 2005-08-11 2010-07-06 Agilent Technologies, Inc. Controlling use of oligonucleotide sequences released from arrays
US8658608B2 (en) * 2005-11-23 2014-02-25 Yale University Modified triple-helix forming oligonucleotides for targeted mutagenesis
RU2394915C2 (ru) * 2006-03-24 2010-07-20 Александр Борисович Четверин Бесконтактные способы обнаружения молекулярных колоний, наборы реагентов и устройство для их осуществления
EP2099911A2 (de) * 2007-01-11 2009-09-16 Yale University Zusammensetzungen und verfahren zur gezielten deaktivierung von hiv-zelloberflächen-rezeptoren
WO2008130263A1 (fr) 2007-04-20 2008-10-30 Institut Molekulyarnoi Biologii Im V.A. Engeldardta Rossiskoi Akademii Nauk Monomère et composition destinés à la réception d'hydrogel à faible pourcentage et/ou de l'hydrogel possédant une faible quantité de réticulations transversales, hydrogel et la biopuce basés sur cet hydrogel
EP3663750B1 (de) 2009-05-29 2021-11-03 Life Technologies Corporation Nukleinsäuregerüstpolymerpartikel und verfahren zur herstellung und verwendung
WO2013006824A2 (en) 2011-07-07 2013-01-10 Life Technologies Corporation Polymer particles, nucleic acid polymer particles and methods of making and using the same
CN104321355A (zh) 2012-02-17 2015-01-28 Nvs技术股份有限公司 用于测定应用的聚合物支架
JP2015533903A (ja) 2012-10-12 2015-11-26 エヌブイエス テクノロジーズ，インコーポレイティド 直交性反応基を有するポリマーおよびその使用
KR20150135353A (ko) 2013-03-14 2015-12-02 엔브이에스 테크놀로지스 인코포레이티드 생체 분자를 격리시키기 위한 표면 산화 및 관련 방법
CN111394444A (zh) 2013-09-13 2020-07-10 生命技术公司 使用凝聚核酸颗粒的装置制备
EP3416976A2 (de) 2016-02-16 2018-12-26 Yale University Zusammensetzungen zur verbesserung von gezielter geneditierung und verfahren zur verwendung davon

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2003266A1 (de) * 1970-01-26 1971-08-05 Waldhof Zellstoff Fab Verfahren zur Herstellung von Gelen
AU668855B2 (en) * 1990-10-26 1996-05-23 Genta Incorporated Non-aromatic organic polymeric reagents for solid phase synthesis of oligomers
DK51092D0 (da) * 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
FR2679255B1 (fr) * 1991-07-17 1993-10-22 Bio Merieux Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation.
US5495006A (en) * 1991-09-27 1996-02-27 Allelix Biopharmaceuticals, Inc. Antiviral polynucleotide conjugates
DE4322884A1 (de) * 1992-10-09 1994-04-14 Bayer Ag Biologisch aktive Polymere
JPH06121698A (ja) * 1992-10-12 1994-05-06 Canon Inc Ｄｎａプローブ用モノマー、ｄｎａプローブ、及びその製造方法

Also Published As

Publication number Publication date
WO1998039351A1 (en) 1998-09-11
JP2001513109A (ja) 2001-08-28
US6180770B1 (en) 2001-01-30
DE69841304D1 (de) 2010-01-07
EP0971943A1 (de) 2000-01-19
EP0971943A4 (de) 2001-03-14
US5932711A (en) 1999-08-03
CA2283798A1 (en) 1998-09-11
EP0971943B1 (de) 2009-11-25
AU6436498A (en) 1998-09-22

Similar Documents

Publication Publication Date Title
ATE449781T1 (de) Nucleinsäure enthaltender polymerisierbarer komplex
KR890010128A (ko) 불소- 및 발색단-함유 중합체
ATE225369T1 (de) Doppelsträngige peptidenukleinsäuren
JPS6411167A (en) Covering material composition
KR890003847A (ko) 중합성 기판 제품
FI850322L (fi) Metod foer framstaellning av en fasta katalytkomponent och anvaendning av denna katalyt foer polymerisering av -olefiner.
KR830002672A (ko) 활성 에스테르 모노머 및 폴리머의 제조방법
BR9004908A (pt) Tiras vedantes de plastico,processo para sua preparacao e sua utilizacao
JPS5271590A (en) Production of novel high polymer
CA2255164A1 (en) Vinyl chloride resin composition
DE69104033D1 (de) Übergangsmetall enthaltende katalysatorzusammensetzung zur polymerisation von olefinen.
CA2032669A1 (en) Process for incorporating o-hydroxyphenyl-s-triazines in organic polymers
BR8008953A (pt) Composicoes, curaveis por oxigenio, de mercaptoorganossiloxana possuindo rapida reacao de superficie e processo de formacao de produtos de peso molecular mais alto a partir das mesmas
DZ1438A1 (fr) Procédé de polymérisation d'une oléfine.
EP0331052A3 (de) Verfahren zur Imidierung von Acrylpolymeren
SE8401437D0 (sv) Ytmodifierade plastytor och dess tillempningar for immunoassays (ia)
JPS55164209A (en) Thermoplastic resin lubricant and lubricating thermoplastic resin composition
JPS57150433A (en) Carrier for immobilizing physiologically active material and selective adsorbent, selective electrode and analytical column using said carrier
DE69017651D1 (de) Verfahren zur Polymerisation von Vinylchlorid.
DE69023546D1 (de) Mehrfache Festphasensynthese von Peptiden.
BR0111104A (pt) Composições radicalmente polimerizáveis contendo monÈmeros mono-funcionais, resinas e artigos oftálmicos obtidos a partir das mesmas, novos monÈmeros mono-funcionais
SU694374A1 (ru) Способ формировани лицевого сло паркетного щита
DE69009712D1 (de) Verfahren zur Suspensionspolymerisation von Vinylchloridmonomeren.
JPS5321224A (en) Coating compositions
KR890005163A (ko) 내γ선성 염화비닐계 수지재료 및 동 염화비닐계 수지의 제조 방법

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties