ATE445666T1 - Chromatographische zweischichtpartikel - Google Patents

Chromatographische zweischichtpartikel

Info

Publication number
ATE445666T1
ATE445666T1 AT03791513T AT03791513T ATE445666T1 AT E445666 T1 ATE445666 T1 AT E445666T1 AT 03791513 T AT03791513 T AT 03791513T AT 03791513 T AT03791513 T AT 03791513T AT E445666 T1 ATE445666 T1 AT E445666T1
Authority
AT
Austria
Prior art keywords
particles
solvent
chromatographic
reactive groups
outer layer
Prior art date
Application number
AT03791513T
Other languages
English (en)
Inventor
Hans Berg
Philippe Busson
Mats Carlsson
Original Assignee
Ge Healthcare Bio Sciences Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Bio Sciences Ab filed Critical Ge Healthcare Bio Sciences Ab
Application granted granted Critical
Publication of ATE445666T1 publication Critical patent/ATE445666T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1807—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3285—Coating or impregnation layers comprising different type of functional groups or interactions, e.g. different ligands in various parts of the sorbent, mixed mode, dual zone, bimodal, multimodal, ionic or hydrophobic, cationic or anionic, hydrophilic or hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
    • B01J41/20—Anion exchangers for chromatographic processes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
AT03791513T 2002-08-27 2003-08-18 Chromatographische zweischichtpartikel ATE445666T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0202551A SE0202551D0 (sv) 2002-08-27 2002-08-27 Chromatographic two-layer particles
PCT/SE2003/001284 WO2004020994A1 (en) 2002-08-27 2003-08-18 Chromatographic two-layer particles

Publications (1)

Publication Number Publication Date
ATE445666T1 true ATE445666T1 (de) 2009-10-15

Family

ID=20288829

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03791513T ATE445666T1 (de) 2002-08-27 2003-08-18 Chromatographische zweischichtpartikel

Country Status (10)

Country Link
US (1) US7208093B2 (de)
EP (1) EP1558927B1 (de)
JP (1) JP4424669B2 (de)
CN (1) CN100406114C (de)
AT (1) ATE445666T1 (de)
AU (1) AU2003251275A1 (de)
CA (1) CA2495491C (de)
DE (1) DE60329701D1 (de)
SE (1) SE0202551D0 (de)
WO (1) WO2004020994A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0202551D0 (sv) * 2002-08-27 2002-08-27 Amersham Biosciences Ab Chromatographic two-layer particles
SE0502485L (sv) * 2005-11-09 2007-05-10 Peter Viberg Partiklar
CN101765458B (zh) * 2007-07-25 2014-05-28 通用电气健康护理生物科学股份公司 分离基质
JP5596560B2 (ja) * 2008-02-05 2014-09-24 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 分離媒体の製造方法
WO2009131526A1 (en) * 2008-04-22 2009-10-29 Ge Healthcare Bio-Sciences Ab Chromatography medium
US9314712B2 (en) * 2008-05-09 2016-04-19 Dionex Corporation Functionalized substrates with ion-exchange properties
JP2012500651A (ja) * 2008-08-25 2012-01-12 ジーイー・ヘルスケア・バイオサイエンス・コーポレイション ゲノムｄｎａの精製のための簡単な負荷および溶離プロセス
CN102821843A (zh) * 2010-02-19 2012-12-12 通用电气健康护理生物科学股份公司 色谱介质的制备方法
US9782468B2 (en) 2013-05-20 2017-10-10 Shantha Biotechnics Private Limited Purification of polysaccharide protein conjugates
JP2015013583A (ja) * 2013-07-05 2015-01-22 株式会社ジェイテクト 電動パワーステアリング装置
RU2665442C2 (ru) * 2013-10-10 2018-08-29 ДжиИ Хелткер Биопроцесс АрЭндДи АБ Способ получения хроматографического материала
EP3116645B1 (de) * 2014-03-14 2019-04-10 GE Healthcare BioProcess R&D AB Trennmatrizen zur aufreinigung biologischer partikel
CN104741090B (zh) * 2015-03-19 2017-08-29 深圳职业技术学院 一种扩张床吸附(eba)介质和其制备方法
CN104744585B (zh) * 2015-03-30 2018-07-17 深圳职业技术学院 一种扩张床吸附（eba）技术制备纤维蛋白原的工艺方法
GB201506117D0 (en) * 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
GB201506113D0 (en) 2015-04-10 2015-05-27 Ge Healthcare Bio Sciences Ab Method for chromatography
CN108531563A (zh) * 2018-02-05 2018-09-14 深圳市尚维高科有限公司 多孔微球的用途及裂解液以及裂解液的使用方法
WO2022252071A1 (en) * 2021-05-31 2022-12-08 Suzhou Sepax Technologies, Inc A synthetic polymeric porous medium with hierarchical multiple layer structure, its design, synthesis, modification, and liquid chromatographic applications

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Publication number Priority date Publication date Assignee Title
DE2800464A1 (de) * 1978-01-05 1979-07-12 Bayer Ag Verfahren zur erzeugung hochbelegter substanzzonen im sorbens von duennschichtchromatographieplatten
US5110784A (en) * 1984-04-09 1992-05-05 Dow Corning Corporation Dual surface porous material
US4778600A (en) * 1987-06-17 1988-10-18 Dow Corning Corporation Liquid chromatography dual zone packing materials
US4773994A (en) * 1987-06-17 1988-09-27 Dow Corning Corporation Liquid chromatography packing materials
US4897197A (en) * 1987-06-17 1990-01-30 Dow Corning Corporation Using liquid chromatography packing materials
US4855054A (en) * 1987-06-17 1989-08-08 Dow Corning Corporation Using liquid chromatography dual zone packing materials
US4941974A (en) * 1987-06-17 1990-07-17 Dow Corning Corporation Method of making liquid chromatography dual zone packing materials
US4950634A (en) * 1988-02-11 1990-08-21 Dow Corning Corporation Method for producing dual zone materials by use of an organosilane mixture
US4950635A (en) * 1988-02-11 1990-08-21 Dow Corning Corporation Method for producing dual zone materials by catalyzed halosilylation
CA2015832C (en) * 1989-05-15 2002-05-28 Eric K. Eisenhart Multi-stage polymer particles having a hydrophobically-modified, ionically-soluble stage
US5512169A (en) * 1992-12-30 1996-04-30 Dow Corning Corporation Liquid column packing materials
EP0691376B1 (de) * 1994-01-24 1999-08-04 Sumitomo Chemical Company Limited Harzzusammensetzung, laminat und verbundfolie
US5522994A (en) * 1995-02-01 1996-06-04 Cornell Research Foundation, Inc. Single column chromatographic determination of small molecules in mixtures with large molecules
SE9700383D0 (sv) * 1997-02-04 1997-02-04 Pharmacia Biotech Ab An adsorption/separation method and a medium for adsorption/separation
SE9700768D0 (sv) * 1997-03-04 1997-03-04 Pharmacia Biotech Ab Förfarande för att introducera funktionalitet
SE9700769D0 (sv) * 1997-03-04 1997-03-04 Pharmacia Biotech Ab Matriser för separation och separation som utnyttjar matriserna
SE0202551D0 (sv) * 2002-08-27 2002-08-27 Amersham Biosciences Ab Chromatographic two-layer particles

Also Published As

Publication number Publication date
JP2005537479A (ja) 2005-12-08
CA2495491A1 (en) 2004-03-11
US20050242037A1 (en) 2005-11-03
CA2495491C (en) 2011-06-14
CN1678903A (zh) 2005-10-05
EP1558927B1 (de) 2009-10-14
WO2004020994A1 (en) 2004-03-11
DE60329701D1 (de) 2009-11-26
JP4424669B2 (ja) 2010-03-03
SE0202551D0 (sv) 2002-08-27
US7208093B2 (en) 2007-04-24
AU2003251275A1 (en) 2004-03-19
CN100406114C (zh) 2008-07-30
EP1558927A1 (de) 2005-08-03

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