ATE438673T1 - Polysiloxanprepolymere für biomedizinische vorrichtungen - Google Patents

Polysiloxanprepolymere für biomedizinische vorrichtungen

Info

Publication number
ATE438673T1
ATE438673T1 AT05851722T AT05851722T ATE438673T1 AT E438673 T1 ATE438673 T1 AT E438673T1 AT 05851722 T AT05851722 T AT 05851722T AT 05851722 T AT05851722 T AT 05851722T AT E438673 T1 ATE438673 T1 AT E438673T1
Authority
AT
Austria
Prior art keywords
independently
polysiloxane
biomedical devices
dii
polysiloxane prepolymers
Prior art date
Application number
AT05851722T
Other languages
English (en)
Inventor
Yu-Chin Lai
Weihong Lang
Edmond Quinn
Original Assignee
Bausch & Lomb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch & Lomb filed Critical Bausch & Lomb
Application granted granted Critical
Publication of ATE438673T1 publication Critical patent/ATE438673T1/de

Links

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041Lenses
    • G02B1/043Contact lenses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F283/00Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G
    • C08F283/12Macromolecular compounds obtained by polymerising monomers on to polymers provided for in subclass C08G on to polysiloxanes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F290/00Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
    • C08F290/02Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated end groups
    • C08F290/06Polymers provided for in subclass C08G
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08Processes
    • C08G18/10Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/61Polysiloxanes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/67Unsaturated compounds having active hydrogen
    • C08G18/671Unsaturated compounds having only one group containing active hydrogen
    • C08G18/672Esters of acrylic or alkyl acrylic acid having only one group containing active hydrogen
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72Polyisocyanates or polyisothiocyanates
    • C08G18/74Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/75Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic
    • C08G18/751Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring
    • C08G18/752Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring containing at least one isocyanate or isothiocyanate group linked to the cycloaliphatic ring by means of an aliphatic group
    • C08G18/753Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring containing at least one isocyanate or isothiocyanate group linked to the cycloaliphatic ring by means of an aliphatic group containing one isocyanate or isothiocyanate group linked to the cycloaliphatic ring by means of an aliphatic group having a primary carbon atom next to the isocyanate or isothiocyanate group
    • C08G18/755Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic containing only one cycloaliphatic ring containing at least one isocyanate or isothiocyanate group linked to the cycloaliphatic ring by means of an aliphatic group containing one isocyanate or isothiocyanate group linked to the cycloaliphatic ring by means of an aliphatic group having a primary carbon atom next to the isocyanate or isothiocyanate group and at least one isocyanate or isothiocyanate group linked to a secondary carbon atom of the cycloaliphatic ring, e.g. isophorone diisocyanate
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/16Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2210/00Compositions for preparing hydrogels
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/31504Composite [nonstructural laminate]
    • Y10T428/31652Of asbestos
    • Y10T428/31663As siloxane, silicone or silane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Optics & Photonics (AREA)
  • Eyeglasses (AREA)
  • Materials For Medical Uses (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Silicon Polymers (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Prostheses (AREA)
AT05851722T 2004-12-29 2005-11-14 Polysiloxanprepolymere für biomedizinische vorrichtungen ATE438673T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64015904P 2004-12-29 2004-12-29
PCT/US2005/041540 WO2006071388A1 (en) 2004-12-29 2005-11-14 Polysiloxane prepolymers for biomedical devices

Publications (1)

Publication Number Publication Date
ATE438673T1 true ATE438673T1 (de) 2009-08-15

Family

ID=36123329

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05851722T ATE438673T1 (de) 2004-12-29 2005-11-14 Polysiloxanprepolymere für biomedizinische vorrichtungen

Country Status (10)

Country Link
US (1) US7632876B2 (de)
EP (1) EP1831278B1 (de)
JP (1) JP5074205B2 (de)
CN (1) CN101094878B (de)
AT (1) ATE438673T1 (de)
CA (1) CA2593070A1 (de)
DE (1) DE602005015892D1 (de)
ES (1) ES2329272T3 (de)
MX (1) MX2007007805A (de)
WO (1) WO2006071388A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US7828728B2 (en) 2003-07-25 2010-11-09 Dexcom, Inc. Analyte sensor
JP4708342B2 (ja) 2003-07-25 2011-06-22 デックスコム・インコーポレーテッド 埋設可能な装置に用いる酸素増大膜システム
US8277713B2 (en) 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
US8744546B2 (en) 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
EP2428235B1 (de) 2007-11-23 2014-06-04 Technische Universität Wien Verwendung von durch Polymerisation härtbaren Zusammensetzungen zur Herstellung biologisch abbaubarer, bioverträglicher, vernetzter Polymere
US7781554B2 (en) * 2008-03-05 2010-08-24 Bausch & Lomb Incorporated Polysiloxanes and polysiloxane prepolymers with vinyl or epoxy functionality
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
CN102047101A (zh) * 2008-03-28 2011-05-04 德克斯康公司 用于连续的分析物传感器的聚合物膜
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8560039B2 (en) 2008-09-19 2013-10-15 Dexcom, Inc. Particle-containing membrane and particulate electrode for analyte sensors
AR074110A1 (es) * 2008-11-13 2010-12-22 Novartis Ag Copolimeros de polisiloxano con cadenas de polimero hidrofilicas terminales
KR101930686B1 (ko) 2010-07-30 2018-12-18 노파르티스 아게 가교된 친수성 코팅을 갖는 실리콘 히드로겔 렌즈
WO2012066084A1 (de) * 2010-11-17 2012-05-24 Byk-Chemie Gmbh Aus urethan-basierten, polysiloxan enthaltenden makromonomeren erhältliche copolymere, verfahren zu deren herstellung und deren verwendung
CN103917899B (zh) 2011-10-12 2018-04-03 诺华股份有限公司 通过涂布制备uv吸收性眼用透镜的方法
JP5776516B2 (ja) * 2011-11-29 2015-09-09 信越化学工業株式会社 オルガノポリシロキサン化合物の製造方法並びにその化合物を用いた硬化性組成物
TWI488892B (zh) * 2011-12-29 2015-06-21 Pegavision Corp 親水性矽膠預聚物之製造方法
US9840595B2 (en) 2012-06-25 2017-12-12 Empire Technology Development Llc Silicone rubber
TWI472557B (zh) * 2012-09-25 2015-02-11 Univ Nat Chiao Tung 可溶性二甲基矽氧烷修飾之聚(2-羥基乙基丙烯酸甲酯-甲基丙烯酸)雙性共聚物及其製備方法
EP2932314B1 (de) 2012-12-17 2017-02-01 Novartis AG Verfahren zur herstellung von uv-licht-absorbierenden brillengläsern
US9708087B2 (en) 2013-12-17 2017-07-18 Novartis Ag Silicone hydrogel lens with a crosslinked hydrophilic coating
KR102366047B1 (ko) 2014-08-26 2022-02-23 알콘 인코포레이티드 실리콘 히드로겔 콘택트 렌즈 상에 안정한 코팅을 적용하는 방법
JP6356042B2 (ja) * 2014-10-28 2018-07-11 大日精化工業株式会社 ポリシロキサン基含有重合体及び熱硬化被膜
CA2996949C (en) * 2015-08-31 2020-10-27 Cohera Medical, Inc. Meniscal repair adhesive
HUE051613T2 (hu) 2015-12-15 2021-03-01 Alcon Inc Eljárás szilíciumhidrogél-kontaktlencsékre stabil kivonat felvitelére
JP6816264B2 (ja) 2016-09-19 2021-01-20 ダウ シリコーンズ コーポレーション ポリウレタン−ポリオルガノシロキサンコポリマー及びその調製方法
US11672768B2 (en) 2016-09-19 2023-06-13 Dow Silicones Corporation Skin contact adhesive and methods for its preparation and use
US20210022985A1 (en) * 2016-09-19 2021-01-28 Dow Silicones Corporation Copolymer composition for personal care
US20210177726A1 (en) 2017-02-15 2021-06-17 Dow Silicones Corporation Personal care compositions including a polyurethane - polyorganosiloxane copolymer
EP4235274A3 (de) 2017-06-07 2023-09-13 Alcon Inc. Silikonhydrogel-kontaktlinsen
AU2018279285B2 (en) 2017-06-07 2020-12-17 Alcon Inc. Silicone hydrogel contact lenses
EP3634732B8 (de) 2017-06-07 2021-10-27 Alcon Inc. Verfahren zur herstellung von silikonhydrogel-kontaktlinsen
WO2019116139A1 (en) 2017-12-13 2019-06-20 Novartis Ag Weekly and monthly disposable water gradient contact lenses

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US526000A (en) * 1894-09-11 Combined corn and cotton planter
CS108895A (de) * 1961-12-27
NL128305C (de) * 1963-09-11
US4197266A (en) * 1974-05-06 1980-04-08 Bausch & Lomb Incorporated Method for forming optical lenses
US4113224A (en) * 1975-04-08 1978-09-12 Bausch & Lomb Incorporated Apparatus for forming optical lenses
US4136250A (en) * 1977-07-20 1979-01-23 Ciba-Geigy Corporation Polysiloxane hydrogels
US4605712A (en) * 1984-09-24 1986-08-12 Ciba-Geigy Corporation Unsaturated polysiloxanes and polymers thereof
US5034461A (en) * 1989-06-07 1991-07-23 Bausch & Lomb Incorporated Novel prepolymers useful in biomedical devices
US5128434A (en) * 1990-11-27 1992-07-07 Bausch & Lomb Incorporated Control of hard segment size in polyurethane formation
US5271875A (en) * 1991-09-12 1993-12-21 Bausch & Lomb Incorporated Method for molding lenses
US5310779A (en) * 1991-11-05 1994-05-10 Bausch & Lomb Incorporated UV curable crosslinking agents useful in copolymerization
US5260000A (en) 1992-08-03 1993-11-09 Bausch & Lomb Incorporated Process for making silicone containing hydrogel lenses
US5760100B1 (en) * 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US6218503B1 (en) * 1998-05-15 2001-04-17 Bausch & Lomb Incorporated Silicone-containing prepolymers
US20060142525A1 (en) * 2004-12-29 2006-06-29 Bausch & Lomb Incorporated Hydrogel copolymers for biomedical devices
ATE425198T1 (de) * 2004-12-29 2009-03-15 Bausch & Lomb Polysiloxanprepolymere für biomedizinische vorrichtungen

Also Published As

Publication number Publication date
US20060142526A1 (en) 2006-06-29
EP1831278B1 (de) 2009-08-05
CN101094878A (zh) 2007-12-26
JP2008525615A (ja) 2008-07-17
DE602005015892D1 (de) 2009-09-17
EP1831278A1 (de) 2007-09-12
WO2006071388A1 (en) 2006-07-06
US7632876B2 (en) 2009-12-15
CN101094878B (zh) 2011-04-13
CA2593070A1 (en) 2006-07-06
JP5074205B2 (ja) 2012-11-14
ES2329272T3 (es) 2009-11-24
MX2007007805A (es) 2007-09-14

Similar Documents

Publication Publication Date Title
ATE438673T1 (de) Polysiloxanprepolymere für biomedizinische vorrichtungen
ATE425198T1 (de) Polysiloxanprepolymere für biomedizinische vorrichtungen
NO20090445L (no) Cykliske 11-beta hydroksysteroid-dehydrogenase type 1 inhibitorer
IS7629A (is) Skiptitengdar heterósýklískar afleiður, og aðferð, gagnlegar sem virk efni gegn sykursýki og offitu
BR0213015B1 (pt) elastÈmeros termoplásticos de poliuretano-silicone.
CY1108471T1 (el) Μεθοδος για την παραγωγη εστερων σκοπινης
AR064412A1 (es) Curativo de triamina/aspartato y recubrimientos que lo incluyen
ATE382647T1 (de) Polymere zur verwendung für organische elektrolumineszenzvorrichtungen
IL186571A (en) Element connects
UA90720C2 (en) Heteroaroyl-substituted serine amides
WO2003100602A3 (en) A scalar/vector processor
EP2191794A3 (de) Medizinische Vorrichtungen
CA2407439A1 (en) Individual venous valve prosthesis
MX9804623A (es) Precursores inactivos de farmacos inhibidores de trombina.
MXPA05007884A (es) Composicion de uretano fluoroquimico para tratamiento de sustratos fibrosos.
WO2006119309A3 (en) 19,26,27-TRINOR-1α,25-DIHYDROXYVITAMIN D3 COMPOUNDS
AR048235A1 (es) Un procedimiento para la sintesis de (7-metoxi-3,4-dihidro-1-naftalenil)acetonitrilo y su aplicacion en la sintesis de agomelatina
DE602006005500D1 (de) Gelenkschiene
ATE502603T1 (de) Universelles implantat für thyroplastik
TW200732320A (en) Pyrazoles useful in the treatment of inflammation
PT1831209E (pt) Inibidores de fosfatases cdc25
MY131129A (en) Foams containing silicon
DE60208371D1 (de) Hydrophiles elastomeres silikon-material, insbesondere zur anfertigung von dentalabdrücken
MXPA05008245A (es) Productos de pano limpiador de papel tratados con una composicion de polisiloxano.
DE69411759D1 (de) Acryllatex zur bildung photovernetzbarer films

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties