ATE434448T1 - Zusammensetzungen und verfahren zur verstärkung der verabreichung von therapeutischen mitteln in zellen - Google Patents
Zusammensetzungen und verfahren zur verstärkung der verabreichung von therapeutischen mitteln in zellenInfo
- Publication number
- ATE434448T1 ATE434448T1 AT98934359T AT98934359T ATE434448T1 AT E434448 T1 ATE434448 T1 AT E434448T1 AT 98934359 T AT98934359 T AT 98934359T AT 98934359 T AT98934359 T AT 98934359T AT E434448 T1 ATE434448 T1 AT E434448T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- cells
- methods
- therapeutic agents
- enhanced delivery
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/889,355 US7002027B1 (en) | 1996-01-08 | 1997-07-08 | Compositions and methods for therapeutic use |
PCT/US1998/014241 WO1999002191A1 (en) | 1997-07-08 | 1998-07-08 | Compositions and methods for enhancing delivery of therapeutic agents to cells |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE434448T1 true ATE434448T1 (de) | 2009-07-15 |
Family
ID=25394956
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT09008139T ATE497786T1 (de) | 1997-07-08 | 1998-07-08 | Zusammensetzungen und kits zur erhöhung der abgabe von therapeutischen mitteln an zellen |
AT98934359T ATE434448T1 (de) | 1997-07-08 | 1998-07-08 | Zusammensetzungen und verfahren zur verstärkung der verabreichung von therapeutischen mitteln in zellen |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT09008139T ATE497786T1 (de) | 1997-07-08 | 1998-07-08 | Zusammensetzungen und kits zur erhöhung der abgabe von therapeutischen mitteln an zellen |
Country Status (21)
Country | Link |
---|---|
US (3) | US7002027B1 (de) |
EP (2) | EP2106807B1 (de) |
JP (2) | JP4460148B2 (de) |
KR (1) | KR100691572B1 (de) |
AR (1) | AR016312A1 (de) |
AT (2) | ATE497786T1 (de) |
AU (1) | AU774338B2 (de) |
CA (1) | CA2294709C (de) |
CY (1) | CY1109367T1 (de) |
DE (2) | DE69842133D1 (de) |
DK (1) | DK1011733T3 (de) |
ES (2) | ES2328094T3 (de) |
HK (2) | HK1028961A1 (de) |
HU (1) | HUP0002683A3 (de) |
IL (1) | IL133929A0 (de) |
MY (1) | MY138257A (de) |
NZ (1) | NZ502060A (de) |
PT (1) | PT1011733E (de) |
TW (1) | TW490306B (de) |
WO (1) | WO1999002191A1 (de) |
ZA (1) | ZA986003B (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6392069B2 (en) * | 1996-01-08 | 2002-05-21 | Canji, Inc. | Compositions for enhancing delivery of nucleic acids to cells |
US7002027B1 (en) * | 1996-01-08 | 2006-02-21 | Canji, Inc. | Compositions and methods for therapeutic use |
US5789244A (en) * | 1996-01-08 | 1998-08-04 | Canji, Inc. | Compositions and methods for the treatment of cancer using recombinant viral vector delivery systems |
US20040014709A1 (en) * | 1996-01-08 | 2004-01-22 | Canji, Inc. | Methods and compositions for interferon therapy |
EP1070047A2 (de) | 1998-04-08 | 2001-01-24 | Celltech Chiroscience Limited | Lipide |
PT1456377T (pt) * | 2001-12-20 | 2019-09-10 | Merck Sharp & Dohme | Composições de syn3 e processos |
CN100429220C (zh) * | 2003-06-04 | 2008-10-29 | 坎基股份有限公司 | 用于干扰素治疗的方法和组合物 |
JP2007526219A (ja) * | 2003-06-04 | 2007-09-13 | カンジ,インコーポレイテッド | トランスフェクション薬剤 |
US7790039B2 (en) * | 2003-11-24 | 2010-09-07 | Northwest Biotherapeutics, Inc. | Tangential flow filtration devices and methods for stem cell enrichment |
SG166117A1 (en) * | 2003-12-10 | 2010-11-29 | Canji Inc | Methods and compositions for treatment of interferon-resistant tumors |
US20060127468A1 (en) | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
US8716021B2 (en) * | 2005-09-07 | 2014-05-06 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Use of replicators to prevent gene silencing |
US20110071100A1 (en) * | 2008-05-05 | 2011-03-24 | Tiltan Pharma Ltd. | Sulfobetaines for cancer, obesity, macular degeneration, neurodegenerative diseases |
US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
US20130079382A1 (en) | 2009-10-12 | 2013-03-28 | Larry J. Smith | Methods and Compositions for Modulating Gene Expression Using Oligonucleotide Based Drugs Administered in vivo or in vitro |
US20120147800A1 (en) * | 2010-12-10 | 2012-06-14 | Minyoung Park | Power management in a wireless network having stations with different power capabilities |
MX363465B (es) | 2011-02-18 | 2019-03-25 | Kythera Biopharmaceuticals Inc | Tratamiento de la grasa submental. |
US8653058B2 (en) | 2011-04-05 | 2014-02-18 | Kythera Biopharmaceuticals, Inc. | Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits |
US10492104B2 (en) * | 2016-03-10 | 2019-11-26 | Cable Television Laboratories, Inc. | Latency reduction in wireless service |
Family Cites Families (50)
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US5554386A (en) | 1986-07-03 | 1996-09-10 | Advanced Magnetics, Inc. | Delivery of therapeutic agents to receptors using polysaccharides |
US5166320A (en) | 1987-04-22 | 1992-11-24 | University Of Connecticut | Carrier system and method for the introduction of genes into mammalian cells |
US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
US5108921A (en) | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
US6207454B1 (en) * | 1989-10-16 | 2001-03-27 | Amgen Inc. | Method for enhancing the effciency of gene transfer with stem cell factor (SCF) polypeptide |
US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
US5542935A (en) | 1989-12-22 | 1996-08-06 | Imarx Pharmaceutical Corp. | Therapeutic delivery systems related applications |
US5279833A (en) | 1990-04-04 | 1994-01-18 | Yale University | Liposomal transfection of nucleic acids into animal cells |
US5264618A (en) * | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
US5120316A (en) * | 1990-09-28 | 1992-06-09 | Akzo N.V. | Urethral catheter and catheterization process |
JPH07500961A (ja) | 1990-10-01 | 1995-02-02 | ユニバーシティ オブ コネチカット | 細胞による選択的内在化を目的としたウイルス及び細胞の標的設定 |
FI106800B (fi) * | 1990-12-06 | 2001-04-12 | Hoechst Ag | Menetelmä uusien terapeuttisesti käyttökelpoisten dimeeristen sappihappojohdannaisten valmistamiseksi |
DE69233725T2 (de) | 1991-06-28 | 2009-02-12 | The Regents Of The University Of Michigan, Ann Arbor | Verwendung von DNA oder RNA zur Herstellung eines Medikaments zur Behandlung von Tumoren |
JPH06509578A (ja) | 1991-07-26 | 1994-10-27 | ユニバーシティ・オブ・ロチェスター | 悪性細胞利用による癌治療法 |
US5283185A (en) | 1991-08-28 | 1994-02-01 | University Of Tennessee Research Corporation | Method for delivering nucleic acids into cells |
US5521291A (en) | 1991-09-30 | 1996-05-28 | Boehringer Ingelheim International, Gmbh | Conjugates for introducing nucleic acid into higher eucaryotic cells |
US6013638A (en) * | 1991-10-02 | 2000-01-11 | The United States Of America As Represented By The Department Of Health And Human Services | Adenovirus comprising deletions on the E1A, E1B and E3 regions for transfer of genes to the lung |
US5795870A (en) * | 1991-12-13 | 1998-08-18 | Trustees Of Princeton University | Compositions and methods for cell transformation |
AU3434393A (en) | 1992-01-17 | 1993-08-03 | Regents Of The University Of Michigan, The | Targeted virus |
US5602023A (en) * | 1992-03-24 | 1997-02-11 | Csatary; Laszlo K. | Pharmaceutical product containing live, stabilized virus for the therapy of viral and malignant diseases and process for preparing the same |
ATE260679T1 (de) | 1992-04-03 | 2004-03-15 | Univ California | Selbstorganisierendes system zur verabreichung von polynukleotiden enthaltend ein amphiphatisches peptid |
JPH07505773A (ja) | 1992-04-03 | 1995-06-29 | ヤング アレキサンダー ティー | 標的化されたウイルスベクターを用いた遺伝子治療 |
US5334761A (en) | 1992-08-28 | 1994-08-02 | Life Technologies, Inc. | Cationic lipids |
US5656609A (en) | 1992-09-24 | 1997-08-12 | University Of Connecticut | Method of enhancing and/or prolonging expression of gene introduced into a cell using colchicine |
WO1994006923A1 (en) | 1992-09-24 | 1994-03-31 | The University Of Connecticut | Modification of a virus to redirect infectivity and enhance targeted delivery of polynucleotides to cells |
US5346701A (en) | 1993-02-22 | 1994-09-13 | Theratech, Inc. | Transmucosal delivery of macromolecular drugs |
US5578475A (en) | 1993-07-12 | 1996-11-26 | Life Technologies, Inc. | Composition and methods for transfecting eukaryotic cells |
US5804566A (en) * | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
US5631236A (en) * | 1993-08-26 | 1997-05-20 | Baylor College Of Medicine | Gene therapy for solid tumors, using a DNA sequence encoding HSV-Tk or VZV-Tk |
JPH07109983A (ja) * | 1993-10-13 | 1995-04-25 | Nippondenso Co Ltd | スクロール型圧縮機 |
DE69431959T2 (de) | 1993-10-15 | 2003-11-06 | Cytrx Corp | Therapeutische abgabesysteme und verfahren für ihre verwendung |
BR9407956A (pt) | 1993-10-25 | 1996-11-26 | Canji Inc | Composiçao farmacêutica vetor de express o de adenovirus recombinante e kit par reduzir a proliferaçao de células tumorais |
US6210939B1 (en) * | 1993-10-25 | 2001-04-03 | Canji, Inc. | Recombinant adenoviral vector and methods of use |
US5837533A (en) * | 1994-09-28 | 1998-11-17 | American Home Products Corporation | Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent |
US5552309A (en) | 1994-09-30 | 1996-09-03 | Indiana University Foundation | Use of polyols for improving the introduction of genetic material into cells |
US7163925B1 (en) * | 1995-07-17 | 2007-01-16 | Board Of Regents, The University Of Texas System | p16 expression constructs and their application in cancer therapy |
AU6600396A (en) * | 1995-07-28 | 1997-02-26 | David E. Kohne | Method for enhancing chemiluminescence |
US6392069B2 (en) * | 1996-01-08 | 2002-05-21 | Canji, Inc. | Compositions for enhancing delivery of nucleic acids to cells |
US5789244A (en) * | 1996-01-08 | 1998-08-04 | Canji, Inc. | Compositions and methods for the treatment of cancer using recombinant viral vector delivery systems |
US20040014709A1 (en) * | 1996-01-08 | 2004-01-22 | Canji, Inc. | Methods and compositions for interferon therapy |
US7002027B1 (en) | 1996-01-08 | 2006-02-21 | Canji, Inc. | Compositions and methods for therapeutic use |
US5671110A (en) | 1996-01-23 | 1997-09-23 | Oneac Corporation | Ground skew protection method and apparatus |
US6283940B1 (en) * | 1997-08-29 | 2001-09-04 | S. Grant Mulholland | Catheter |
US6938069B1 (en) * | 2000-03-18 | 2005-08-30 | Computing Services Support Solutions | Electronic meeting center |
PT1456377T (pt) * | 2001-12-20 | 2019-09-10 | Merck Sharp & Dohme | Composições de syn3 e processos |
KR100499787B1 (ko) * | 2002-11-29 | 2005-07-07 | 인티그런트 테크놀로지즈(주) | 스위치 모드 동작을 하는 선형성이 우수한 광대역 가변이득 증폭기 |
JP2007526219A (ja) * | 2003-06-04 | 2007-09-13 | カンジ,インコーポレイテッド | トランスフェクション薬剤 |
CN100429220C (zh) * | 2003-06-04 | 2008-10-29 | 坎基股份有限公司 | 用于干扰素治疗的方法和组合物 |
WO2004108898A2 (en) | 2003-06-04 | 2004-12-16 | Canji, Inc. | Transfection agents |
SG166117A1 (en) | 2003-12-10 | 2010-11-29 | Canji Inc | Methods and compositions for treatment of interferon-resistant tumors |
-
1997
- 1997-07-08 US US08/889,355 patent/US7002027B1/en not_active Expired - Fee Related
-
1998
- 1998-07-07 MY MYPI98003070A patent/MY138257A/en unknown
- 1998-07-07 ZA ZA986003A patent/ZA986003B/xx unknown
- 1998-07-08 WO PCT/US1998/014241 patent/WO1999002191A1/en not_active Application Discontinuation
- 1998-07-08 AT AT09008139T patent/ATE497786T1/de not_active IP Right Cessation
- 1998-07-08 DK DK98934359T patent/DK1011733T3/da active
- 1998-07-08 HU HU0002683A patent/HUP0002683A3/hu unknown
- 1998-07-08 EP EP09008139A patent/EP2106807B1/de not_active Expired - Lifetime
- 1998-07-08 NZ NZ502060A patent/NZ502060A/en not_active IP Right Cessation
- 1998-07-08 JP JP2000501781A patent/JP4460148B2/ja not_active Expired - Fee Related
- 1998-07-08 AU AU83901/98A patent/AU774338B2/en not_active Ceased
- 1998-07-08 DE DE69842133T patent/DE69842133D1/de not_active Expired - Lifetime
- 1998-07-08 AR ARP980103311A patent/AR016312A1/es unknown
- 1998-07-08 ES ES98934359T patent/ES2328094T3/es not_active Expired - Lifetime
- 1998-07-08 KR KR1020007000178A patent/KR100691572B1/ko not_active IP Right Cessation
- 1998-07-08 ES ES09008139T patent/ES2362027T3/es not_active Expired - Lifetime
- 1998-07-08 CA CA2294709A patent/CA2294709C/en not_active Expired - Fee Related
- 1998-07-08 PT PT98934359T patent/PT1011733E/pt unknown
- 1998-07-08 EP EP98934359A patent/EP1011733B1/de not_active Expired - Lifetime
- 1998-07-08 DE DE69840932T patent/DE69840932D1/de not_active Expired - Lifetime
- 1998-07-08 IL IL13392998A patent/IL133929A0/xx unknown
- 1998-07-08 AT AT98934359T patent/ATE434448T1/de active
-
1999
- 1999-01-11 TW TW087111049A patent/TW490306B/zh not_active IP Right Cessation
-
2000
- 2000-12-21 HK HK00108262.4A patent/HK1028961A1/xx not_active IP Right Cessation
-
2006
- 2006-02-21 US US11/359,997 patent/US7538093B2/en not_active Expired - Fee Related
-
2009
- 2009-04-13 US US12/422,807 patent/US8022044B2/en not_active Expired - Fee Related
- 2009-09-15 CY CY20091100949T patent/CY1109367T1/el unknown
- 2009-12-24 JP JP2009293390A patent/JP2010070565A/ja not_active Withdrawn
-
2010
- 2010-02-04 HK HK10101219.1A patent/HK1134025A1/xx not_active IP Right Cessation
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