ATE429488T1 - Verfahren zur stabilisierung von alkalischer phosphatase - Google Patents

Verfahren zur stabilisierung von alkalischer phosphatase

Info

Publication number
ATE429488T1
ATE429488T1 AT02738901T AT02738901T ATE429488T1 AT E429488 T1 ATE429488 T1 AT E429488T1 AT 02738901 T AT02738901 T AT 02738901T AT 02738901 T AT02738901 T AT 02738901T AT E429488 T1 ATE429488 T1 AT E429488T1
Authority
AT
Austria
Prior art keywords
alkaline phosphatase
preparation
stabilizing
freeze
stabilizing alkaline
Prior art date
Application number
AT02738901T
Other languages
English (en)
Inventor
Shigeru Ueda
Toshiaki Hirayama
Original Assignee
Asahi Kasei Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Kasei Pharma Corp filed Critical Asahi Kasei Pharma Corp
Application granted granted Critical
Publication of ATE429488T1 publication Critical patent/ATE429488T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
AT02738901T 2001-07-02 2002-07-02 Verfahren zur stabilisierung von alkalischer phosphatase ATE429488T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001200612 2001-07-02
PCT/JP2002/006673 WO2003004633A1 (fr) 2001-07-02 2002-07-02 Procede de stabilisation de la phosphatase alcaline

Publications (1)

Publication Number Publication Date
ATE429488T1 true ATE429488T1 (de) 2009-05-15

Family

ID=19037707

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02738901T ATE429488T1 (de) 2001-07-02 2002-07-02 Verfahren zur stabilisierung von alkalischer phosphatase

Country Status (8)

Country Link
US (1) US20040197885A1 (de)
EP (1) EP1418229B1 (de)
JP (1) JP4169344B2 (de)
CN (1) CN1306029C (de)
AT (1) ATE429488T1 (de)
DE (1) DE60232080D1 (de)
ES (1) ES2322132T3 (de)
WO (1) WO2003004633A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008501639A (ja) * 2004-04-23 2008-01-24 ノベシン リミテッド タンパク質を安定化、保護及び可溶化させるための方法及びキット
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
CN102109430B (zh) 2009-12-25 2013-11-06 深圳迈瑞生物医疗电子股份有限公司 有核红细胞模拟粒子，血液质控物及其制备方法和用途
CN102115737B (zh) * 2009-12-31 2015-06-03 深圳迈瑞生物医疗电子股份有限公司 稳定碱性磷酸酶或其标记物的试剂和方法
CN102269762B (zh) 2010-06-04 2014-12-10 深圳迈瑞生物医疗电子股份有限公司 结合物的制备方法及相关试剂盒
CN102269761A (zh) 2010-06-04 2011-12-07 深圳迈瑞生物医疗电子股份有限公司 一种碱性磷酸酶结合物的合成工艺
JP6155647B2 (ja) * 2012-01-13 2017-07-05 東洋紡株式会社 フルクトシルバリルヒスチジンオキシダーゼ製剤の製造方法
CN102636639A (zh) * 2012-04-19 2012-08-15 上海蓝怡科技有限公司 碱性磷酸酶标记物的稀释液
CN102628863B (zh) * 2012-04-19 2016-05-11 上海蓝怡科技有限公司 标记了碱性磷酸酶抗原抗体稀释液
JP6520153B2 (ja) * 2015-01-29 2019-05-29 東ソー株式会社 酵素結合小分子の製造方法
CN109900900B (zh) * 2019-04-18 2022-02-01 珠海丽珠试剂股份有限公司 一种适用于碱性磷酸酶标记降钙素原抗原或抗体的稀释液及其试剂盒
CN112680502A (zh) * 2020-12-07 2021-04-20 郑州标源生物科技有限公司 一种碱性磷酸酶质控物及其制备方法
CN118086244A (zh) * 2023-08-18 2024-05-28 北京中检葆泰生物技术有限公司 一种乳源碱性磷酸酶标准品的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK159276C (da) * 1980-03-31 1991-02-18 Takeda Chemical Industries Ltd Fremgangsmaade til isolering af specifikke antistoffer og enzym-immunbestemmelsesmetode med anvendelse af det isolerede antistof
CA2051092C (en) * 1990-09-12 2002-07-23 Stephen A. Livesey Method and apparatus for cryopreparation, dry stabilization and rehydration of biological suspensions
JP3140797B2 (ja) * 1991-04-26 2001-03-05 生化学工業株式会社 安定化コンドロイチナーゼａｂｃ、その保存方法及び治療剤
JPH06284885A (ja) * 1993-04-02 1994-10-11 Tosoh Corp 組換えヒト小腸アルカリフォスファタ−ゼ
US5955448A (en) * 1994-08-19 1999-09-21 Quadrant Holdings Cambridge Limited Method for stabilization of biological substances during drying and subsequent storage and compositions thereof
WO1996003034A1 (en) * 1994-07-27 1996-02-08 Massachusetts Institute Of Technology Method for retroviral vector insertion in fish
JPH08131171A (ja) * 1994-11-11 1996-05-28 Asahi Chem Ind Co Ltd 逆転写酵素の安定化組成物
JP3219181B2 (ja) * 1995-01-10 2001-10-15 東洋紡績株式会社 コレステロールオキシダーゼの安定化法
JPH08228774A (ja) * 1995-02-27 1996-09-10 Toagosei Co Ltd ペルオキシダーゼまたはペルオキシダーゼ標識抗体の安定化方法
US5876992A (en) * 1996-07-03 1999-03-02 Molecular Biology Resources, Inc. Method and formulation for stabilization of enzymes
GB9705588D0 (en) * 1997-03-18 1997-05-07 Anglia Research Foundation Stable particle in liquid formulations

Also Published As

Publication number Publication date
ES2322132T3 (es) 2009-06-17
EP1418229A1 (de) 2004-05-12
US20040197885A1 (en) 2004-10-07
DE60232080D1 (de) 2009-06-04
WO2003004633A1 (fr) 2003-01-16
JPWO2003004633A1 (ja) 2004-10-28
CN1522298A (zh) 2004-08-18
JP4169344B2 (ja) 2008-10-22
EP1418229B1 (de) 2009-04-22
CN1306029C (zh) 2007-03-21
EP1418229A4 (de) 2005-04-27

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