TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
US7517886B2
(en)
|
2002-07-29 |
2009-04-14 |
Rigel Pharmaceuticals, Inc. |
Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
|
CN102358738A
(zh)
|
2003-07-30 |
2012-02-22 |
里格尔药品股份有限公司 |
2,4-嘧啶二胺化合物及其预防和治疗自体免疫疾病的用途
|
WO2006020145A2
(en)
*
|
2004-07-19 |
2006-02-23 |
The Johns Hopkins University |
Flt3 inhibitors for immune suppression
|
DE102005018389A1
(de)
|
2005-04-20 |
2006-10-26 |
Sanofi-Aventis Deutschland Gmbh |
Azolderivate als Inhibitoren von Lipasen und Phospholipasen
|
MX2007014619A
(es)
*
|
2005-05-20 |
2009-02-13 |
Vertex Pharma |
Pirrolopiridinas de utilidad como inhibidores de proteina quinasa.
|
GB0510922D0
(en)
*
|
2005-05-27 |
2005-07-06 |
Fond Ct San Rafaelle Del Monte |
Hsi
|
EP3002330A1
(de)
|
2005-05-27 |
2016-04-06 |
Ospedale San Raffaele S.r.l. |
Genvektor
|
WO2006133426A2
(en)
|
2005-06-08 |
2006-12-14 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
US20060281788A1
(en)
|
2005-06-10 |
2006-12-14 |
Baumann Christian A |
Synergistic modulation of flt3 kinase using a flt3 inhibitor and a farnesyl transferase inhibitor
|
US7825244B2
(en)
|
2005-06-10 |
2010-11-02 |
Janssen Pharmaceutica Nv |
Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
|
US8071768B2
(en)
|
2005-06-10 |
2011-12-06 |
Janssen Pharmaceutica, N.V. |
Alkylquinoline and alkylquinazoline kinase modulators
|
MX2008001538A
(es)
*
|
2005-08-02 |
2008-04-04 |
Lexicon Pharmaceuticals Inc |
Aril piridinas y metodos para su uso.
|
CA2626623C
(en)
|
2005-10-18 |
2016-08-30 |
Janssen Pharmaceutica N.V. |
Method of inhibiting flt3 kinase
|
CA2642229C
(en)
|
2006-02-24 |
2015-05-12 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
JP5331681B2
(ja)
|
2006-04-20 |
2013-10-30 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
c−fmsキナーゼの阻害剤
|
US8697716B2
(en)
|
2006-04-20 |
2014-04-15 |
Janssen Pharmaceutica Nv |
Method of inhibiting C-KIT kinase
|
MX2008013533A
(es)
|
2006-04-20 |
2009-01-15 |
Janssen Pharmaceutica Nv |
Compuestos heterociclicos como inhibidores de c-fms cinasa.
|
WO2008049123A2
(en)
|
2006-10-19 |
2008-04-24 |
Rigel Pharmaceuticals, Inc. |
2,4-pyrimidinediamine derivatives as inhibitors of jak kinases for the treatment of autoimmune diseases
|
WO2008082840A1
(en)
*
|
2006-12-29 |
2008-07-10 |
Abbott Laboratories |
Pim kinase inhibitors as cancer chemotherapeutics
|
JO3240B1
(ar)
|
2007-10-17 |
2018-03-08 |
Janssen Pharmaceutica Nv |
c-fms مثبطات كيناز
|
AU2008343173A1
(en)
|
2007-12-19 |
2009-07-09 |
Aj Park |
Pyrazolo [1,5-a] pyrimidines useful as JAK2 inhibitors
|
NZ587589A
(en)
|
2008-02-15 |
2012-10-26 |
Rigel Pharmaceuticals Inc |
Pyrimidine-2-amine compounds and their use as inhibitors of jak kinases
|
CA2717034A1
(en)
|
2008-02-28 |
2009-09-03 |
Pascal Furet |
Imidazo[1,2-b]pyridazine derivatives for the treatment of c-met tyrosine kinase mediated disease
|
US8138339B2
(en)
|
2008-04-16 |
2012-03-20 |
Portola Pharmaceuticals, Inc. |
Inhibitors of protein kinases
|
NZ589315A
(en)
|
2008-04-16 |
2012-11-30 |
Portola Pharm Inc |
2,6-diamino-pyrimidin-5-yl-carboxamides as Spleen tryosine kinase (syk) or Janus kinase (JAK) inhibitors
|
EP2271631B1
(de)
|
2008-04-22 |
2018-07-04 |
Portola Pharmaceuticals, Inc. |
Inhibitoren von proteinkinasen
|
US8987251B2
(en)
|
2008-08-19 |
2015-03-24 |
Array Biopharma Inc. |
Triazolopyridine compounds as PIM kinase inhibitors
|
TWI496779B
(zh)
|
2008-08-19 |
2015-08-21 |
Array Biopharma Inc |
作為pim激酶抑制劑之***吡啶化合物
|
US8895550B2
(en)
|
2008-08-19 |
2014-11-25 |
Array Biopharma Inc. |
Triazolopyridine compounds as PIM kinase inhibitors
|
WO2010022081A1
(en)
|
2008-08-19 |
2010-02-25 |
Array Biopharma Inc. |
Triazolopyridine compounds as pim kinase inhibitors
|
US8389526B2
(en)
|
2009-08-07 |
2013-03-05 |
Novartis Ag |
3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
|
EP2521782B1
(de)
|
2010-01-05 |
2019-04-10 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
FLT3-Rezeptorantagonisten zur Behandlung oder Vorbeugung von Schmerzstörungen
|
SG182480A1
(en)
|
2010-01-12 |
2012-08-30 |
Ab Science |
Thiazole and oxazole kinase inhibitors
|
EP2635557A2
(de)
|
2010-11-01 |
2013-09-11 |
Portola Pharmaceuticals, Inc. |
Nicotinamide als jak-kinasemodulatoren
|
EP2662078A1
(de)
*
|
2010-11-10 |
2013-11-13 |
National Jewish Health |
Verfahren zur Behandlung von allergischen Zuständen
|
WO2012154274A1
(en)
|
2011-02-25 |
2012-11-15 |
Array Biopharma Inc. |
Triazolopyridine compounds as pim kinase inhibitors
|
AU2012232658B2
(en)
|
2011-03-22 |
2016-06-09 |
Advinus Therapeutics Limited |
Substituted fused tricyclic compounds, compositions and medicinal applications thereof
|
WO2012143144A1
(en)
|
2011-04-21 |
2012-10-26 |
Origenis Gmbh |
Pyrazolo [4, 3-d] pyrimidines useful as kinase inhibitors
|
IN2014CN04065A
(de)
|
2011-11-23 |
2015-09-04 |
Portola Pharm Inc |
|
US9096579B2
(en)
|
2012-04-20 |
2015-08-04 |
Boehringer Ingelheim International Gmbh |
Amino-indolyl-substituted imidazolyl-pyrimidines and their use as medicaments
|
SG10201704095UA
(en)
|
2012-04-24 |
2017-06-29 |
Vertex Pharma |
Dna-pk inhibitors
|
JOP20180012A1
(ar)
|
2012-08-07 |
2019-01-30 |
Janssen Pharmaceutica Nv |
عملية السلفنة باستخدام نونافلوروبوتانيسولفونيل فلوريد
|
EP2882757B1
(de)
|
2012-08-07 |
2016-10-05 |
Janssen Pharmaceutica, N.V. |
Verfahren zur herstellung heterocyclischer esterderivate
|
JP6407504B2
(ja)
|
2012-09-21 |
2018-10-17 |
アログ・ファーマシューティカルズ・インコーポレイテッドArog Pharmaceuticals,Inc. |
恒常的に活性であるリン酸化型flt3キナーゼの阻害方法
|
JP2015529242A
(ja)
|
2012-09-21 |
2015-10-05 |
アドヴィヌス セラピューティクス リミテッドAdvinus Therapeutics Limited |
置換された縮合三環式化合物、組成物およびその医薬用途
|
WO2014058921A2
(en)
|
2012-10-08 |
2014-04-17 |
Portola Pharmaceuticals, Inc. |
Substituted pyrimidinyl kinase inhibitors
|
US9637491B2
(en)
|
2012-10-19 |
2017-05-02 |
Origenis Gmbh |
Pyrazolo[4,3-D]pyrimidines as kinase inhibitors
|
BR112015016282A2
(pt)
|
2013-01-07 |
2017-07-11 |
Arog Pharmaceuticals Inc |
crenolanibe para tratamento de distúrbios proliferativos de flt3 mutado
|
CN107200749B
(zh)
|
2013-03-12 |
2019-09-03 |
沃泰克斯药物股份有限公司 |
Dna-pk抑制剂
|
EP3057953B1
(de)
|
2013-10-17 |
2018-08-15 |
Vertex Pharmaceuticals Incorporated |
Co-kristalle von (s)-n-methyl-8-(1-((2'-methyl-[4,5'-bipyrimidin]-6-yl)amino)propan-2-yl)chinolin-4-carboxamid und deuterierten derivaten davon als dna-pk-hemmer
|
US10463658B2
(en)
|
2013-10-25 |
2019-11-05 |
Videra Pharmaceuticals, Llc |
Method of inhibiting FLT3 kinase
|
US10065937B2
(en)
|
2014-07-31 |
2018-09-04 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
FLT3 receptor antagonists
|
EP3254698A1
(de)
|
2016-06-08 |
2017-12-13 |
Universite De Montpellier |
Flt3-rezeptor-inhibitoren bei niedriger dosierung zur behandlung von neuropathischem schmerz
|
US11352328B2
(en)
|
2016-07-12 |
2022-06-07 |
Arisan Therapeutics Inc. |
Heterocyclic compounds for the treatment of arenavirus
|
TW201815418A
(zh)
|
2016-09-27 |
2018-05-01 |
Vertex Pharma |
使用dna破壞劑及dna-pk抑制劑之組合治療癌症的方法
|
WO2018085292A1
(en)
|
2016-11-02 |
2018-05-11 |
Arog Pharmaceuticals, Inc. |
Crenolanib for treating flt3 mutated proliferative disorders associated mutations
|
WO2018211018A1
(en)
|
2017-05-17 |
2018-11-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Flt3 inhibitors for improving pain treatments by opioids
|
WO2019057649A1
(en)
|
2017-09-19 |
2019-03-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIA
|
WO2022019998A1
(en)
|
2020-07-20 |
2022-01-27 |
Arog Pharmaceuticals, Inc. |
Crystal forms of crenolanib and methods of use thereof
|