ATE421507T1 - Quinazolin derivate als antitumor-mittel - Google Patents

Quinazolin derivate als antitumor-mittel

Info

Publication number
ATE421507T1
ATE421507T1 AT02774961T AT02774961T ATE421507T1 AT E421507 T1 ATE421507 T1 AT E421507T1 AT 02774961 T AT02774961 T AT 02774961T AT 02774961 T AT02774961 T AT 02774961T AT E421507 T1 ATE421507 T1 AT E421507T1
Authority
AT
Austria
Prior art keywords
tumor agent
quinazoline derivatives
quinazoline
derivatives
tumor
Prior art date
Application number
AT02774961T
Other languages
English (en)
Inventor
Laurent Hennequin
Jason Kettle
Martin Pass
Robert Bradbury
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE421507T1 publication Critical patent/ATE421507T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
    • C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
    • C04B35/632—Organic additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
AT02774961T 2001-11-03 2002-10-31 Quinazolin derivate als antitumor-mittel ATE421507T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0126433.2A GB0126433D0 (en) 2001-11-03 2001-11-03 Compounds

Publications (1)

Publication Number Publication Date
ATE421507T1 true ATE421507T1 (de) 2009-02-15

Family

ID=9925096

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02774961T ATE421507T1 (de) 2001-11-03 2002-10-31 Quinazolin derivate als antitumor-mittel

Country Status (25)

Country Link
US (2) US20050054662A1 (de)
EP (1) EP1444211B1 (de)
JP (1) JP2005511603A (de)
KR (1) KR20050042058A (de)
CN (1) CN1764651A (de)
AR (1) AR037193A1 (de)
AT (1) ATE421507T1 (de)
BR (1) BR0213843A (de)
CA (1) CA2465100A1 (de)
CO (1) CO5580775A2 (de)
DE (1) DE60230995D1 (de)
ES (1) ES2319880T3 (de)
GB (1) GB0126433D0 (de)
HK (1) HK1065801A1 (de)
HU (1) HUP0401994A2 (de)
IL (1) IL161620A0 (de)
IS (1) IS7241A (de)
MX (1) MXPA04004220A (de)
NO (1) NO20042288L (de)
NZ (1) NZ532523A (de)
PL (1) PL369833A1 (de)
RU (1) RU2004116908A (de)
TW (1) TW200302221A (de)
WO (1) WO2003040109A2 (de)
ZA (2) ZA200403203B (de)

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KR20060100388A (ko) * 2003-09-25 2006-09-20 아스트라제네카 아베 퀴나졸린 유도체
GB0322409D0 (en) * 2003-09-25 2003-10-29 Astrazeneca Ab Quinazoline derivatives
GB0326459D0 (en) * 2003-11-13 2003-12-17 Astrazeneca Ab Quinazoline derivatives
US7632840B2 (en) * 2004-02-03 2009-12-15 Astrazeneca Ab Quinazoline compounds for the treatment of hyperproliferative disorders
EP1756088A1 (de) * 2004-06-04 2007-02-28 AstraZeneca AB Chinazolinderivate als erbb-rezeptortyrosinkinasen

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HK1065801A1 (en) 2005-03-04
RU2004116908A (ru) 2005-11-10
CA2465100A1 (en) 2003-05-15
EP1444211A2 (de) 2004-08-11
GB0126433D0 (en) 2002-01-02
IL161620A0 (en) 2004-09-27
HUP0401994A2 (hu) 2005-01-28
TW200302221A (en) 2003-08-01
ES2319880T3 (es) 2009-05-14
BR0213843A (pt) 2004-08-31
NZ532523A (en) 2007-02-23
NO20042288L (no) 2004-06-03
CO5580775A2 (es) 2005-11-30
ZA200403200B (en) 2005-07-28
US20050054662A1 (en) 2005-03-10
EP1444211B1 (de) 2009-01-21
PL369833A1 (en) 2005-05-02
ZA200403203B (en) 2005-07-28
DE60230995D1 (de) 2009-03-12
CN1764651A (zh) 2006-04-26
MXPA04004220A (es) 2004-09-10
WO2003040109A2 (en) 2003-05-15
US20070088044A1 (en) 2007-04-19
JP2005511603A (ja) 2005-04-28
KR20050042058A (ko) 2005-05-04
IS7241A (is) 2004-04-30
AR037193A1 (es) 2004-10-27
WO2003040109A3 (en) 2003-06-26

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