ATE419333T1 - Peptidgerüstverkapselung von gewebszellen und verwendungen davon - Google Patents
Peptidgerüstverkapselung von gewebszellen und verwendungen davonInfo
- Publication number
- ATE419333T1 ATE419333T1 AT02717398T AT02717398T ATE419333T1 AT E419333 T1 ATE419333 T1 AT E419333T1 AT 02717398 T AT02717398 T AT 02717398T AT 02717398 T AT02717398 T AT 02717398T AT E419333 T1 ATE419333 T1 AT E419333T1
- Authority
- AT
- Austria
- Prior art keywords
- cells
- vitro
- transdifferentiation
- differentiation
- provides
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0012—Cell encapsulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
- C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1317—Chondrocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Developmental Biology & Embryology (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/778,200 US7449180B2 (en) | 2001-02-06 | 2001-02-06 | Macroscopic scaffold containing amphiphilic peptides encapsulating cells |
US30537901P | 2001-07-13 | 2001-07-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE419333T1 true ATE419333T1 (de) | 2009-01-15 |
Family
ID=26974566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02717398T ATE419333T1 (de) | 2001-02-06 | 2002-02-06 | Peptidgerüstverkapselung von gewebszellen und verwendungen davon |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1367961B1 (de) |
JP (2) | JP5057629B2 (de) |
AT (1) | ATE419333T1 (de) |
DE (1) | DE60230593D1 (de) |
WO (2) | WO2002062961A2 (de) |
Families Citing this family (95)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2453381A1 (en) * | 2001-07-10 | 2003-01-23 | Massachusetts Institute Of Technology | Methods for ex vivo propagation of somatic stem cells |
AU2002365162A1 (en) | 2001-11-14 | 2003-07-09 | Northwestern University | Self-assembly and mineralization of peptide-amphiphile nanofibers |
WO2003069972A2 (en) | 2002-02-15 | 2003-08-28 | Massachusetts Institute Of Technology | Hepatocyte precursor cell lines |
AU2003215280A1 (en) | 2002-02-15 | 2003-09-09 | Northwestern University | Self-assembly of peptide-amphiphile nanofibers under physiological conditions |
US7534761B1 (en) | 2002-08-21 | 2009-05-19 | North Western University | Charged peptide-amphiphile solutions and self-assembled peptide nanofiber networks formed therefrom |
US7554021B2 (en) | 2002-11-12 | 2009-06-30 | Northwestern University | Composition and method for self-assembly and mineralization of peptide amphiphiles |
WO2004046167A2 (en) | 2002-11-14 | 2004-06-03 | Northwestern University | Synthesis and self-assembly of abc triblock bola peptide |
NZ541718A (en) | 2003-02-11 | 2008-04-30 | Univ Northwestern | Methods and materials for nanocrystalline surface coatings and attachment of peptide amphiphile nanofibers thereon |
EP2711025A3 (de) * | 2003-06-25 | 2014-09-10 | Massachusetts Institute of Technology | Selbstangeordnete Peptide mit Modifikationen und Verwendungsverfahren dafür |
US7713923B2 (en) | 2003-06-25 | 2010-05-11 | Massachusetts Institute Of Technology | Self-assembling peptides incorporating modifications and methods of use thereof |
US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
US8491883B2 (en) | 2003-06-27 | 2013-07-23 | Advanced Technologies And Regenerative Medicine, Llc | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
CA2530533C (en) | 2003-06-27 | 2015-02-10 | Ethicon, Incorporated | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
CA2457296A1 (en) | 2003-08-19 | 2005-02-19 | Takahiro Ochiya | Methods for inducing differentiation of pluripotent cells |
US20050053586A1 (en) * | 2003-09-04 | 2005-03-10 | Bryan Conn | Entrapped stem cells and uses thereof |
EP1670493A4 (de) * | 2003-10-10 | 2007-10-24 | Transform Pharmaceuticals Inc | In vitro-entwicklung von geweben und organen |
US7704740B2 (en) | 2003-11-05 | 2010-04-27 | Michigan State University | Nanofibrillar structure and applications including cell and tissue culture |
WO2005056576A2 (en) | 2003-12-05 | 2005-06-23 | Northwestern University | Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof |
MXPA06006388A (es) | 2003-12-05 | 2006-09-04 | Univ Northwestern | Peptidos anfifilicos de auto-ensamble y metodos relacionados para el suministro del factor de crecimiento. |
US7655465B2 (en) | 2004-06-07 | 2010-02-02 | Massachusetts Institute Of Technology | Methods for ex vivo propagation of somatic hair follicle stem cells |
GB0415080D0 (en) | 2004-07-05 | 2004-08-04 | Ucl Biomedica Plc | Methods for preparing tissue equivalent implants and products thereof |
EP3031466B1 (de) * | 2004-07-06 | 2018-11-28 | 3D Matrix, Inc. | Gereinigte zusammensetzungen amphiphiler peptide und verwendungen davon |
US8039258B2 (en) | 2004-09-28 | 2011-10-18 | Ethicon, Inc. | Tissue-engineering scaffolds containing self-assembled-peptide hydrogels |
US20060069008A1 (en) | 2004-09-28 | 2006-03-30 | Sanjay Mistry | Treatment of neurological deficits in the striatum or substanta nigra pars compacta |
PL1835924T3 (pl) | 2004-12-23 | 2014-01-31 | Ethicon Incorporated | Leczenie choroby Parkinsona i zaburzeń związanych z tą chorobą z użyciem komórek uzyskiwanych po porodzie |
EP1833504A4 (de) * | 2005-01-04 | 2009-08-12 | Brigham & Womens Hospital | Dauerhafte abgabe von selbstanordnende peptidnanofaser nutzendem pdgf |
EP1838846A4 (de) * | 2005-01-21 | 2008-12-10 | Univ Northwestern | Verfahren und zusammensetzungen zur verkapselung von zellen |
KR20070108555A (ko) | 2005-03-04 | 2007-11-12 | 노오쓰웨스턴 유니버시티 | 혈관신생 헤파린 결합 펩티드 양친매성 화합물 |
ES2427565T3 (es) | 2005-04-25 | 2013-10-31 | Massachusetts Institute Of Technology | Péptidos autoensambladores para promover la hemostasia |
US9162005B2 (en) | 2005-04-25 | 2015-10-20 | Arch Biosurgery, Inc. | Compositions for prevention of adhesions and other barrier applications |
AU2011253661B2 (en) * | 2005-04-26 | 2013-06-13 | Boehringer Ingelheim Rcv Gmbh & Co Kg | Production of recombinant proteins by autoproteolytic cleavage of a fusion protein |
US8163890B2 (en) * | 2005-04-26 | 2012-04-24 | Sandoz Ag | Production of recombinant proteins by autoproteolytic cleavage of a fusion protein |
JP2006346420A (ja) * | 2005-06-13 | 2006-12-28 | Univ Nagoya | 移植材料及び骨質改善剤 |
US7824912B2 (en) | 2005-06-23 | 2010-11-02 | Massachusetts Institute Of Technology | Methods for ex vivo propagation of adult hepatic stem cells |
US8299032B2 (en) | 2005-06-27 | 2012-10-30 | Menicon Co., Ltd. | Self-assembling peptide and gel produced from the same |
JP2007039394A (ja) * | 2005-08-04 | 2007-02-15 | Nippon Menaade Keshohin Kk | 老化予防改善皮膚外用剤 |
WO2007037407A1 (ja) | 2005-09-30 | 2007-04-05 | 3-D Matrix Japan, Ltd. | 細胞の培養方法および細胞培養物 |
JP4982841B2 (ja) * | 2005-10-12 | 2012-07-25 | 国立大学法人名古屋大学 | 再生医療骨組成物 |
US9175261B2 (en) | 2005-12-16 | 2015-11-03 | DePuy Synthes Products, Inc. | Human umbilical cord tissue cells for inhibiting adverse immune response in histocompatibility-mismatched transplantation |
US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
JP2007217376A (ja) * | 2006-02-17 | 2007-08-30 | Nagoya Institute Of Technology | 自己組織化ペプチド組成物 |
JP2007217375A (ja) * | 2006-02-17 | 2007-08-30 | Nagoya Institute Of Technology | 自己組織化ペプチド |
CN101472620A (zh) | 2006-04-25 | 2009-07-01 | 麻省理工学院 | 用于影响污染物、机体流体或其它实体移动和/或影响其它生理状况的组合物和方法 |
EP2066697A2 (de) * | 2006-09-26 | 2009-06-10 | Massachusetts Institute of Technology | Modifizierte selbstanordnende peptide |
DE102007006843A1 (de) | 2007-02-12 | 2008-08-14 | Bioregeneration Gmbh | Verfahren und Stützstruktur zum Kultivieren lebender Zellen |
JP2010521495A (ja) * | 2007-03-14 | 2010-06-24 | アーチ セラピューティクス, インコーポレイテッド | 漏出性または損傷を受けたタイトジャンクションの処置および細胞外マトリクスの増強 |
US8076295B2 (en) | 2007-04-17 | 2011-12-13 | Nanotope, Inc. | Peptide amphiphiles having improved solubility and methods of using same |
JP5568008B2 (ja) * | 2007-06-27 | 2014-08-06 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | ペプチドチロシナーゼインヒビターおよびその使用 |
EP2229960B1 (de) * | 2007-12-05 | 2015-04-08 | 3-D Matrix, Ltd. | Material zur wundheilung/hautrekonstruktion |
CN101939418A (zh) | 2008-01-30 | 2011-01-05 | 杰龙公司 | 用于培养干细胞衍生的心肌细胞的合成表面 |
US8329469B2 (en) | 2008-01-30 | 2012-12-11 | Geron Corporation | Swellable (meth)acrylate surfaces for culturing cells in chemically defined media |
CN105331577A (zh) | 2008-01-30 | 2016-02-17 | 阿斯特利亚斯生物治疗股份公司 | 用于培养干细胞衍生的少突胶质细胞前体细胞的合成表面 |
KR20110007600A (ko) | 2008-01-30 | 2011-01-24 | 제론 코포레이션 | 세포배양 제품 및 스크리닝하는 방법 |
EP3238749B1 (de) | 2008-10-06 | 2018-09-19 | 3-D Matrix Ltd. | Gewebestecker |
EP2379087B1 (de) | 2008-12-19 | 2014-08-20 | DePuy Synthes Products, LLC | Aus nabelschnurgewebe gewonnene zellen zur behandlung von neuropathischen schmerzen und spastizität |
US10557116B2 (en) | 2008-12-19 | 2020-02-11 | DePuy Synthes Products, Inc. | Treatment of lung and pulmonary diseases and disorders |
US20130302283A1 (en) | 2012-05-14 | 2013-11-14 | Advanced Technologies And Regenerative Medicine, Llc | hUTC MODULATION OF PRO-INFLAMMATORY MEDIATORS OF LUNG AND PULMONARY DISEASES AND DISORDERS |
US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
SG174551A1 (en) | 2009-03-26 | 2011-10-28 | Ethicon Inc | Human umbilical cord tissue cells as therapy for alzheimer' s disease |
EP2419116A1 (de) | 2009-04-13 | 2012-02-22 | North Western University | Neue peptidbasierte gerüste für knorpelregenerierung und anwendungsverfahren dafür |
US8362144B2 (en) | 2009-05-21 | 2013-01-29 | Corning Incorporated | Monomers for making polymeric cell culture surface |
US9084752B2 (en) * | 2009-12-14 | 2015-07-21 | The University Of Hong Kong | Compositions and methods for controlling proliferation and differentiation of cells |
WO2011072482A1 (en) | 2009-12-14 | 2011-06-23 | The University Of Hong Kong | Nano cancer barrier device(ncbd) to immobilize and inhibit the division of metastic cancer stem cells |
JP5732691B2 (ja) * | 2010-01-14 | 2015-06-10 | 学校法人同志社 | インスリン製剤 |
US9067084B2 (en) * | 2010-03-31 | 2015-06-30 | Agency For Science, Technology And Research | Amphiphilic linear peptide/peptoid and hydrogel comprising the same |
KR101029705B1 (ko) | 2010-06-30 | 2011-04-18 | (주)엔솔테크 | 신규 펩타이드 및 그 용도 |
JP2013538864A (ja) * | 2010-10-08 | 2013-10-17 | ソルヴェイ(ソシエテ アノニム) | 生物活性アミノ酸配列及びその使用 |
JP2012082180A (ja) * | 2010-10-14 | 2012-04-26 | Nagoya Univ | 骨再生用自己組織化ペプチドハイドロゲル |
US9943592B2 (en) | 2011-05-26 | 2018-04-17 | Kansas State University Research Foundation | Vaccine adjuvants from self-assembling peptides |
PL2741755T3 (pl) | 2011-08-10 | 2018-07-31 | DePuy Synthes Products, Inc. | Leczenie choroby naczyń obwodowych przy użyciu komórek pochodzących z tkanki pępowinowej |
BR112014015424A2 (pt) | 2011-12-23 | 2018-05-22 | Depuy Synthes Products Llc | detecção de células derivadas de tecido do cordão umbilical humano |
GB201203085D0 (en) | 2012-02-22 | 2012-04-04 | Univ Manchester | Hydrogels |
CN102718841B (zh) * | 2012-06-27 | 2013-11-13 | 深圳翰宇药业股份有限公司 | 一种肽生物材料的纯化方法 |
EP2869903B1 (de) | 2012-07-06 | 2018-11-28 | 3-D Matrix Ltd. | Füllabschlussverfahren für peptidlösungen |
CA2886109A1 (en) * | 2012-12-07 | 2014-06-12 | Kansas State University Research Foundation | Peptide-albumin hydrogel properties and its applications |
KR101501436B1 (ko) * | 2013-02-14 | 2015-03-18 | 주식회사 나이벡 | 생리활성 펩타이드가 자기회합된 젤 형태의 지지체 및 그 제조방법 |
WO2015027203A1 (en) | 2013-08-22 | 2015-02-26 | Arch Biosurgery, Inc. | Implantable meshes for controlling the movement of fluids |
EP3116524B1 (de) | 2014-03-10 | 2018-11-28 | 3-D Matrix Ltd. | Peptides autoassémblants pour le traitement de la bulle pulmonaire |
US10369237B2 (en) | 2014-03-10 | 2019-08-06 | 3-D Matrix, Ltd. | Sterilization and filtration of peptide compositions |
AU2015229549B2 (en) | 2014-03-10 | 2019-05-23 | 3-D Matrix, Ltd. | Self-assembling peptide compositions |
DE102015000363A1 (de) | 2015-01-20 | 2016-07-21 | Emc Microcollections Gmbh | Neue modular funktionalisierbare Peptid-Hydrogele |
CN104650192B (zh) * | 2015-03-26 | 2017-06-23 | 罗忠礼 | 一类能用于修复子宫和保护心肌的自组装短肽及其应用 |
CN105148289B (zh) * | 2015-09-30 | 2018-10-09 | 南京中医药大学 | 一种两亲性寡聚多肽药物结合物 |
WO2017120092A1 (en) | 2016-01-06 | 2017-07-13 | 3-D Matrix, Ltd. | Combination compositions |
WO2018220622A2 (en) * | 2017-05-29 | 2018-12-06 | Orgenesis Ltd. | Compositions and methods for providing cell replacement therapy |
CN107446897A (zh) * | 2017-08-09 | 2017-12-08 | 国家***第三海洋研究所 | 一种鱼肝脏粗酶液冻干粉及其制备方法 |
CN117085140A (zh) | 2017-12-15 | 2023-11-21 | 立美基股份有限公司 | 表面活性剂肽纳米结构及在药物递送中的用途 |
WO2020171161A1 (ja) * | 2019-02-20 | 2020-08-27 | 国立大学法人東京農工大学 | 自己組織化ペプチド |
RU2731314C1 (ru) * | 2019-10-30 | 2020-09-01 | Общество С Ограниченной Ответственностью "Международный Центр Медицинских Исследований И Разработок" (Ооо "Мц Миир") | Способ производства клеточных сфероидов для восстановления хрящей |
RU2750021C1 (ru) * | 2020-08-26 | 2021-06-21 | Общество С Ограниченной Ответственностью "Международный Центр Медицинских Исследований И Разработок" (Ооо "Мц Миир") | Способ восстановления диафизов длинных трубчатых костей с применением клеточных технологий |
US20230392123A1 (en) * | 2020-10-15 | 2023-12-07 | Katholieke Universiteit Leuven | Spheroidal self-assembled peptide hydrogels comprising cells |
WO2022236187A1 (en) | 2021-05-07 | 2022-11-10 | Children's Hospital Los Angeles | Methods for making stem cell-derived enteric neural crest cells and their use in enteric neuropathy treatment |
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US5955343A (en) * | 1992-12-28 | 1999-09-21 | Massachusetts Institute Of Technology | Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor |
US5670483A (en) * | 1992-12-28 | 1997-09-23 | Massachusetts Insititute Of Technology | Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor |
US5834029A (en) * | 1994-07-20 | 1998-11-10 | Cytotherapeutics, Inc. | Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment |
US6129761A (en) * | 1995-06-07 | 2000-10-10 | Reprogenesis, Inc. | Injectable hydrogel compositions |
DE69837141T2 (de) * | 1997-05-12 | 2007-10-31 | Metabolix, Inc., Cambridge | Polyhydroxyalkanoate für in vivo anwendungen |
US6368877B1 (en) * | 1997-06-25 | 2002-04-09 | Massachusetts Institute Of Technology | Self-assembling peptide surfaces for cell patterning and interactions |
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2002
- 2002-02-06 DE DE60230593T patent/DE60230593D1/de not_active Expired - Lifetime
- 2002-02-06 WO PCT/US2002/003482 patent/WO2002062961A2/en active Application Filing
- 2002-02-06 EP EP02717398A patent/EP1367961B1/de not_active Expired - Lifetime
- 2002-02-06 JP JP2002563298A patent/JP5057629B2/ja not_active Expired - Lifetime
- 2002-02-06 AT AT02717398T patent/ATE419333T1/de not_active IP Right Cessation
- 2002-02-06 WO PCT/US2002/003607 patent/WO2002062969A2/en not_active Application Discontinuation
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2010
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WO2002062969A2 (en) | 2002-08-15 |
EP1367961A2 (de) | 2003-12-10 |
WO2002062961A2 (en) | 2002-08-15 |
JP5057629B2 (ja) | 2012-10-24 |
JP2005515796A (ja) | 2005-06-02 |
WO2002062961A9 (en) | 2002-10-31 |
WO2002062969A9 (en) | 2002-10-17 |
WO2002062961A3 (en) | 2003-07-24 |
DE60230593D1 (de) | 2009-02-12 |
EP1367961B1 (de) | 2008-12-31 |
WO2002062969A3 (en) | 2002-11-28 |
JP2010069330A (ja) | 2010-04-02 |
EP1367961A4 (de) | 2004-07-21 |
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