ATE419022T1 - Hydrophobe mehrkomponenten-heparinkonjugate, ein verfahren zur ihrer herstellung und verwendung - Google Patents
Hydrophobe mehrkomponenten-heparinkonjugate, ein verfahren zur ihrer herstellung und verwendungInfo
- Publication number
- ATE419022T1 ATE419022T1 AT00973237T AT00973237T ATE419022T1 AT E419022 T1 ATE419022 T1 AT E419022T1 AT 00973237 T AT00973237 T AT 00973237T AT 00973237 T AT00973237 T AT 00973237T AT E419022 T1 ATE419022 T1 AT E419022T1
- Authority
- AT
- Austria
- Prior art keywords
- heparin conjugates
- hydrophobic
- production
- present
- conjugates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0081—Reaction with amino acids, peptides, or proteins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Materials For Medical Uses (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2000-0062668A KR100378109B1 (ko) | 2000-10-24 | 2000-10-24 | 소수성 다중복합 헤파린 결합체, 그의 제조방법 및 용도 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE419022T1 true ATE419022T1 (de) | 2009-01-15 |
Family
ID=19695171
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00973237T ATE419022T1 (de) | 2000-10-24 | 2000-11-03 | Hydrophobe mehrkomponenten-heparinkonjugate, ein verfahren zur ihrer herstellung und verwendung |
Country Status (9)
Country | Link |
---|---|
US (1) | US7129224B1 (de) |
EP (1) | EP1333871B1 (de) |
JP (1) | JP3927118B2 (de) |
KR (1) | KR100378109B1 (de) |
CN (1) | CN1209171C (de) |
AT (1) | ATE419022T1 (de) |
AU (1) | AU2001211769A1 (de) |
DE (1) | DE60041283D1 (de) |
WO (1) | WO2002034312A1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100449889B1 (ko) * | 2001-08-30 | 2004-09-22 | 동국제약 주식회사 | 음이온 고분자와 인지질의 결합체가 함유된 인지질 리포좀및 그의 제조방법과 응용 |
US7438925B2 (en) * | 2002-08-26 | 2008-10-21 | Biovention Holdings Ltd. | Drug eluting coatings for medical implants |
US6702850B1 (en) | 2002-09-30 | 2004-03-09 | Mediplex Corporation Korea | Multi-coated drug-eluting stent for antithrombosis and antirestenosis |
US8293890B2 (en) | 2004-04-30 | 2012-10-23 | Advanced Cardiovascular Systems, Inc. | Hyaluronic acid based copolymers |
US7563780B1 (en) * | 2004-06-18 | 2009-07-21 | Advanced Cardiovascular Systems, Inc. | Heparin prodrugs and drug delivery stents formed therefrom |
EP1829567A4 (de) | 2004-12-21 | 2010-07-21 | Univ Shinshu | Medizinisches instrument |
ES2376888T3 (es) | 2005-05-04 | 2012-03-20 | Suprapolix B.V. | Materiales supramoleculares activos biológicamente, modulares biorreabsorbibles o biomédicos |
EP2087027B1 (de) | 2006-11-20 | 2011-10-05 | SupraPolix B.V. | Supramolekulare polymere aus niedrigschmelzenden, leicht verarbeitbaren bausteinen |
US20090281059A1 (en) * | 2007-02-21 | 2009-11-12 | Robert Falotico | Coating for a medical device having an anti-thrombotic conjugate |
US20080200421A1 (en) | 2007-02-21 | 2008-08-21 | Zhao Jonathon Z | Coating for a medical device having an anti-thrombotic conjugate |
US8628789B2 (en) | 2007-03-23 | 2014-01-14 | Suprapolix, B.V. | Strong reversible hydrogels |
US9693841B2 (en) | 2007-04-02 | 2017-07-04 | Ension, Inc. | Surface treated staples, sutures and dental floss and methods of manufacturing the same |
WO2008122034A1 (en) | 2007-04-02 | 2008-10-09 | Ension, Inc. | Process for preparing a substrate coated with a biomolecule |
US8383156B2 (en) | 2007-04-30 | 2013-02-26 | Cordis Corporation | Coating for a medical device having an anti-thrombotic conjugate |
WO2009005258A2 (en) * | 2007-06-29 | 2009-01-08 | Mediplex Corp. | Heparin conjugates and methods |
US8088753B2 (en) * | 2007-06-29 | 2012-01-03 | Mediplex Corporation, Korea | Heparin conjugates and methods |
US20090018646A1 (en) | 2007-07-10 | 2009-01-15 | Zhao Jonathon Z | Coating Employing an Anti-Thrombotic Conjugate |
US20100021538A1 (en) * | 2008-02-29 | 2010-01-28 | Youngro Byun | Pharmaceutical compositions containing heparin derivatives |
EP2310376B1 (de) | 2008-07-04 | 2014-11-05 | SupraPolix B.V. | Supramolekulare verbindungen mit hohem durchfluss |
GB201004101D0 (en) * | 2010-03-12 | 2010-04-28 | Carmeda Ab | Immobilised biological entities |
US9446216B2 (en) | 2010-10-14 | 2016-09-20 | Medtronic, Inc. | Cannular device and method of manufacture |
EP2450394B1 (de) | 2010-11-05 | 2017-06-07 | SupraPolix B.V. | Verfahren zur Herstellung eines supramolekularen Polymers |
CN110776610A (zh) * | 2013-04-26 | 2020-02-11 | 生物相互作用有限公司 | 生物活性涂层 |
CA2912664C (en) * | 2013-05-20 | 2022-07-26 | Yale University | Anti-thrombogenic grafts |
US9339770B2 (en) | 2013-11-19 | 2016-05-17 | Applied Membrane Technologies, Inc. | Organosiloxane films for gas separations |
KR101881541B1 (ko) * | 2016-07-25 | 2018-07-24 | 가톨릭대학교산학협력단 | 골형성 또는 골 유착능 향상을 위한 생분해성 고분자의 표면처리 방법 |
CN106986955B (zh) * | 2017-04-28 | 2019-04-09 | 华南理工大学 | 一种肝素的叠氮化修饰方法和叠氮化肝素及应用 |
CN109925536B (zh) * | 2017-12-15 | 2021-01-26 | 先健科技(深圳)有限公司 | 可吸收铁基植入式器械 |
TWI653993B (zh) | 2018-03-20 | 2019-03-21 | 國立臺灣大學 | 血管取代物 |
CN115990297B (zh) * | 2023-03-09 | 2023-11-07 | 上海宏普医疗器械有限公司 | 一种基于ptfe材料的肝素抗凝涂层及其制备方法 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5357288A (en) | 1976-11-04 | 1978-05-24 | Nippon Zeon Co Ltd | Anticoagulant medical polymer its preparation and use |
JPS6229532A (ja) * | 1985-07-31 | 1987-02-07 | Koken:Kk | 抗血栓性医用材料及びその製造方法 |
JPH01262869A (ja) | 1988-04-15 | 1989-10-19 | Ube Ind Ltd | 抗血液凝固性医療用具 |
US5270046A (en) * | 1988-09-27 | 1993-12-14 | Ube Industries, Ltd. | Heparin bound anti-thrombotic material |
US5069899A (en) * | 1989-11-02 | 1991-12-03 | Sterilization Technical Services, Inc. | Anti-thrombogenic, anti-microbial compositions containing heparin |
GB9009570D0 (en) * | 1990-04-27 | 1990-06-20 | Biocompatibles Ltd | Antithrombogenic polymers |
DE4217917A1 (de) * | 1992-05-30 | 1993-12-02 | Job Prof Dr Med Harenberg | Immobilisation von chemisch kovalent gebundenem Heparin an Polymere mit Arylresten im Polymer |
FR2723847A1 (fr) * | 1994-08-29 | 1996-03-01 | Debiopharm Sa | Compositions antithrombotiques et non hemorragiques a base d'heparine, procede pour leur preparation et applications therapeutiques. |
JP3341503B2 (ja) * | 1994-11-09 | 2002-11-05 | 東レ株式会社 | 抗血栓性医療材料およびそれを用いたカテーテル |
US5744457A (en) * | 1995-03-31 | 1998-04-28 | Hamilton Civic Hospitals Research Development Inc. | Compositions and methods for inhibiting thrombogenesis |
KR0175975B1 (ko) * | 1995-11-03 | 1999-05-15 | 김은영 | 항응혈성 술폰산화 블록 공중합체 및 이로부터 제조된 의료 용품 |
FR2752843B1 (fr) * | 1996-08-30 | 1998-10-16 | Sod Conseils Rech Applic | Copolymeres reticules a base de polymeres polycarboxyliques et leur utilisation comme support de composition pharmaceutique |
US6071532A (en) * | 1996-10-15 | 2000-06-06 | Emory University | Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof |
US6229009B1 (en) * | 1997-08-29 | 2001-05-08 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Polycarboxylic based cross-linked copolymers |
US5955588A (en) * | 1997-12-22 | 1999-09-21 | Innerdyne, Inc. | Non-thrombogenic coating composition and methods for using same |
US6258371B1 (en) * | 1998-04-03 | 2001-07-10 | Medtronic Inc | Method for making biocompatible medical article |
KR100314496B1 (ko) * | 1998-05-28 | 2001-11-22 | 윤동진 | 항혈전성이 있는 헤파린 유도체, 그의 제조방법 및 용도 |
AU3735899A (en) * | 1998-05-28 | 1999-12-13 | Mediplex Corporation, Korea | Amphiphilic polysaccharide derivatives |
JP4358331B2 (ja) * | 1998-11-12 | 2009-11-04 | Junken Medical株式会社 | 透明性の優れた抗血液凝固性材料および抗血液凝固性材料を塗布した医療用具 |
US6702850B1 (en) * | 2002-09-30 | 2004-03-09 | Mediplex Corporation Korea | Multi-coated drug-eluting stent for antithrombosis and antirestenosis |
-
2000
- 2000-10-24 KR KR10-2000-0062668A patent/KR100378109B1/ko not_active IP Right Cessation
- 2000-11-03 AT AT00973237T patent/ATE419022T1/de not_active IP Right Cessation
- 2000-11-03 EP EP00973237A patent/EP1333871B1/de not_active Expired - Lifetime
- 2000-11-03 AU AU2001211769A patent/AU2001211769A1/en not_active Abandoned
- 2000-11-03 WO PCT/KR2000/001255 patent/WO2002034312A1/en active Application Filing
- 2000-11-03 CN CNB008199868A patent/CN1209171C/zh not_active Expired - Fee Related
- 2000-11-03 JP JP2002537363A patent/JP3927118B2/ja not_active Expired - Fee Related
- 2000-11-03 US US10/333,641 patent/US7129224B1/en not_active Expired - Fee Related
- 2000-11-03 DE DE60041283T patent/DE60041283D1/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1333871A1 (de) | 2003-08-13 |
CN1455687A (zh) | 2003-11-12 |
JP3927118B2 (ja) | 2007-06-06 |
AU2001211769A1 (en) | 2002-05-06 |
DE60041283D1 (de) | 2009-02-12 |
KR20020031894A (ko) | 2002-05-03 |
CN1209171C (zh) | 2005-07-06 |
WO2002034312A1 (en) | 2002-05-02 |
EP1333871A4 (de) | 2004-07-07 |
US7129224B1 (en) | 2006-10-31 |
KR100378109B1 (ko) | 2003-03-29 |
JP2004512397A (ja) | 2004-04-22 |
EP1333871B1 (de) | 2008-12-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE419022T1 (de) | Hydrophobe mehrkomponenten-heparinkonjugate, ein verfahren zur ihrer herstellung und verwendung | |
DE60025833D1 (de) | Synthetische melanine auf pflanzenbasis, verfahren zu deren herstellung sowie diese enthaltende zusammensetzungen | |
ATE241948T1 (de) | Wasserabsorbierende polymere mit hohlraumverbindungen, verfahren zu deren herstellung und deren verwendung | |
DE69737834D1 (de) | Folienzusammensetzungen aus Polymerisat zur Herstellung von Kapseln | |
DE502005002359D1 (de) | Verfahren zur herstellung wässriger wirkstoffzusammensetzungen von in wasser schwer löslichen wirkstoffen | |
DE60328421D1 (de) | Verfahren zur herstellung von super-hydrophoben oberflächen, daraus hergestellte oberflächen und deren verwendung | |
DE60036262D1 (de) | Verfahren zur Herstellung von Polymer-Partikeln Komposit | |
DE69917784D1 (de) | Flüssige chitosan-enthaltende zusammensetzungen und verfahren zur herstellung und verwendung | |
DE69940773D1 (de) | Teil-interpenetrierende polymernetzwerke | |
DE60225591D1 (de) | Verfahren zur herstellung einer zusammensetzung enthaltend ein polymer oder copolymer von 3,4-dialko | |
DE60126345D1 (de) | Poly(arylene ether)-enthaltende wärmehärtenden zusammensetzungen, verfahren zur herstellung und daraus gewonnene formkörper | |
WO2005028631A3 (en) | A novel biodegradable elastomeric scaffold for tissue engineering and light scattering fingerprinting methods for testing the same | |
DE602004015907D1 (de) | Konjugierte Dienamide, Verfahren zur deren Herstellung, diese enthaltende Zusammensetzungen sowie deren Verwendung | |
DE60012127D1 (de) | Verfahren zur Herstellung von Perfluoropolyoxyalkylenen mit Hydroxylendgruppen | |
DE502005000428D1 (de) | Verfahren zur Herstellung von 1,2-Diaminocyclohexan-Platin(II)-Komplexen | |
DE60233686D1 (de) | Verfahren zur Herstellung von polymeren phosphorhaltigen Zusammensetzungen | |
DE60102850T2 (de) | Verfahren zur Herstellung von wässrigen Beschichtungszusammensetzungen | |
DE60108372D1 (de) | Verfahren zur herstellung fester reinigungsmittel-komponenten | |
ATE327257T1 (de) | Fester, stabiler und konzentrierter biologisch verdaulicher komplex von orthokieselsäure und prozess zur dessen herstellung | |
DE50100858D1 (de) | Verfahren zur Herstellung von Uretdionpolysocyanaten mit verbesserter Monomerenstabilität | |
DE50212333D1 (de) | Netzwerk auf polysaccharidbasis und verfahren zu dessen herstellung | |
DE60228400D1 (de) | Verfahren zur Herstellung von modifiziertem Polymerkautschuk | |
DE69931367D1 (de) | Konjugierter dien-kautschuk, verfahren zu dessen herstellung und kautschukzusammensetzung | |
DE60115971D1 (de) | Verfahren zur Herstellung von Cellulosepolymeren | |
ATE543855T1 (de) | Verfahren zur herstellung säurefunktioneller polyamidimide |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |