ATE40570T1 - Verfahren zur herstellung eines optisch aktiven 3-(3,4-dihydroxyphenyl)-serins und ein geschuetztes derivat davon. - Google Patents
Verfahren zur herstellung eines optisch aktiven 3-(3,4-dihydroxyphenyl)-serins und ein geschuetztes derivat davon.Info
- Publication number
- ATE40570T1 ATE40570T1 AT84307297T AT84307297T ATE40570T1 AT E40570 T1 ATE40570 T1 AT E40570T1 AT 84307297 T AT84307297 T AT 84307297T AT 84307297 T AT84307297 T AT 84307297T AT E40570 T1 ATE40570 T1 AT E40570T1
- Authority
- AT
- Austria
- Prior art keywords
- dihydroxyphenyl
- serine
- protected derivative
- preparation
- optically active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
- C12P7/38—Cyclopentanone- or cyclopentadione-containing products
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/826—Actinomyces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/908—Streptovirticillium
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP58205859A JPS6098995A (ja) | 1983-11-04 | 1983-11-04 | 光学活性3−(3,4−ジヒドロキシフエニル)セリン,およびその誘導体の製造法 |
EP84307297A EP0141613B1 (de) | 1983-11-04 | 1984-10-24 | Verfahren zur Herstellung eines optisch aktiven 3-(3,4-Dihydroxyphenyl)-Serins und ein geschütztes Derivat davon |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE40570T1 true ATE40570T1 (de) | 1989-02-15 |
Family
ID=16513892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT84307297T ATE40570T1 (de) | 1983-11-04 | 1984-10-24 | Verfahren zur herstellung eines optisch aktiven 3-(3,4-dihydroxyphenyl)-serins und ein geschuetztes derivat davon. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4699879A (de) |
EP (1) | EP0141613B1 (de) |
JP (1) | JPS6098995A (de) |
KR (1) | KR850003572A (de) |
AT (1) | ATE40570T1 (de) |
CA (1) | CA1241612A (de) |
DE (1) | DE3476560D1 (de) |
HU (1) | HU193234B (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990014434A1 (en) * | 1989-05-15 | 1990-11-29 | Schering Corporation | Process for preparing antibacterial compounds and intermediates thereto |
EP0407190A3 (de) * | 1989-07-07 | 1991-03-13 | Schering Corporation | Verfahren zur Herstellung von antibakteriellen Zwischenprodukten mittels enzymatischer Hydrolyse von razemischen Substraten |
US5707836A (en) * | 1995-03-10 | 1998-01-13 | Nitto Chemical Industry Co., Ltd. | Production of alkylene or phenylenediamine disuccinic acid from fumaric acid and a diamine using lyase from microbes |
CA2388050C (en) * | 1999-08-12 | 2008-03-18 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Antibiotic caprazamycins and process for producing the same |
US20040050682A1 (en) * | 2000-12-27 | 2004-03-18 | George Paskalov | Activated water apparatus and methods and products |
ITPD20010031A1 (it) * | 2001-02-09 | 2002-08-09 | Fidia Farmaceutici | Procedimento per la preparazione di fosfatidi puri e loro impiego in campo cosmetico, farmaceutico ed alimentare. |
US6635456B2 (en) | 2001-02-09 | 2003-10-21 | Fidia Farmaceutici S.P.A. | Procedure for the preparation of pure phosphatides with phospholipase D |
JP2005278401A (ja) * | 2002-09-09 | 2005-10-13 | Nippon Kayaku Co Ltd | 光学活性−エリスロ−3−シクロヘキシルセリンの製造方法 |
US20060105036A1 (en) | 2003-05-12 | 2006-05-18 | Stephen Peroutka | Threo-dops controlled release formulation |
US8158149B2 (en) * | 2004-05-12 | 2012-04-17 | Chelsea Therapeutics, Inc. | Threo-DOPS controlled release formulation |
WO2005025561A1 (en) * | 2003-09-04 | 2005-03-24 | Synergia Pharma, Inc. | Compositions and methods for orthostatic intolerance |
BRPI0417780B1 (pt) * | 2003-12-19 | 2016-03-01 | Basf Ag | composto, processo para preparar o mesmo, agente, processos para preparar o mesmo, e para combater vegetação indesejada, e, uso de um composto |
US20080015181A1 (en) | 2006-06-28 | 2008-01-17 | Chelsea Therapeutics, Inc. | Pharmaceutical Compositions Comprising Droxidopa |
ES2500053T3 (es) | 2007-03-09 | 2014-09-29 | Chelsea Therapeutics, Inc. | Composición farmacéutica que comprende droxidopa para el tratamiento de la fibromialgia |
ES2431570T3 (es) | 2007-05-07 | 2013-11-27 | Chelsea Therapeutics, Inc. | Droxidopa y composición farmacéutica de la misma para el tratamiento de los trastornos por déficit de atención |
JP5880913B2 (ja) | 2011-05-17 | 2016-03-09 | 三郎 佐古田 | パーキンソン病の体幹症状(姿勢反射異常)の治療剤 |
CN103086906B (zh) * | 2011-11-03 | 2015-04-01 | 重庆圣华曦药业股份有限公司 | 屈昔多巴的晶型及其制备方法 |
US20130197090A1 (en) | 2012-01-31 | 2013-08-01 | Chelsea Therapeutics, Inc. | Postural stability and incident functions in patients |
US9920342B2 (en) | 2016-05-17 | 2018-03-20 | Divi's Laboratories Limited | Process for the preparation of Droxidopa |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1493643A1 (de) * | 1963-04-26 | 1969-02-06 | Merck & Co Inc | Verfahren zur Spaltung von D,L-alpha-Methyl-beta-(3,4-dihydroxyphenyl)-alanin in seine optischen Antipoden |
US3347752A (en) * | 1965-03-26 | 1967-10-17 | Merck & Co Inc | Microbiological cleavage process for resolving racemic alpha-methyl-beta-(3, 4,-dihydroxyphenyl)-alanine |
US3386888A (en) * | 1965-07-15 | 1968-06-04 | Tanabe Seiyaku Co | Resolution of racemic amino acids |
DE1543323A1 (de) * | 1965-11-02 | 1969-08-07 | Ajinomoto Kk | Verfahren zur Herstellung von L-Serin |
US3669837A (en) * | 1970-03-30 | 1972-06-13 | Parke Davis & Co | Process for producing 3-(3,4-dimethoxyphenyl)l-alanine by resolution |
GB1369462A (en) * | 1971-11-23 | 1974-10-09 | Beecham Group Ltd | Enzymic resolution of racemic n-acyl-dl-amino acids |
US3812009A (en) * | 1972-01-10 | 1974-05-21 | Owens Illinois Inc | Stereospecific process for the preparation of l-3,4-dihydroxyphenylalanine (l-dopa)and analogs thereof |
JPS5037277B2 (de) * | 1972-08-31 | 1975-12-01 | ||
JPS57186495A (en) * | 1981-05-14 | 1982-11-16 | Ube Ind Ltd | Preparation of l-alpha-methylphenylalanine |
-
1983
- 1983-11-04 JP JP58205859A patent/JPS6098995A/ja active Granted
-
1984
- 1984-10-24 AT AT84307297T patent/ATE40570T1/de not_active IP Right Cessation
- 1984-10-24 DE DE8484307297T patent/DE3476560D1/de not_active Expired
- 1984-10-24 EP EP84307297A patent/EP0141613B1/de not_active Expired
- 1984-11-02 CA CA000466969A patent/CA1241612A/en not_active Expired
- 1984-11-02 HU HU844071A patent/HU193234B/hu unknown
- 1984-11-03 KR KR1019840006908A patent/KR850003572A/ko not_active Application Discontinuation
- 1984-11-05 US US06/668,148 patent/US4699879A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH0559719B2 (de) | 1993-08-31 |
CA1241612A (en) | 1988-09-06 |
DE3476560D1 (en) | 1989-03-09 |
HUT38393A (en) | 1986-05-28 |
HU193234B (en) | 1987-08-28 |
EP0141613A2 (de) | 1985-05-15 |
EP0141613A3 (en) | 1985-09-11 |
EP0141613B1 (de) | 1989-02-01 |
US4699879A (en) | 1987-10-13 |
JPS6098995A (ja) | 1985-06-01 |
KR850003572A (ko) | 1985-06-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE40570T1 (de) | Verfahren zur herstellung eines optisch aktiven 3-(3,4-dihydroxyphenyl)-serins und ein geschuetztes derivat davon. | |
DE59108934D1 (de) | Verfahren zur Herstellung von L-Phosphinothricin durch eine gekoppelte enzymatische Reaktion | |
DE69001732D1 (de) | Verfahren zur enantioselektiven herstellung von phenylisoserin-derivaten. | |
DE59813589D1 (de) | Verfahren zur Herstellung von optisch aktiven Aminoalkoholen durch Racematspaltung | |
HUT52162A (en) | New process for producing optically active | |
IE42500L (en) | N-acyl-l-methionines. | |
ES2128959A1 (es) | Procedimiento de separacion de carbinoles. | |
SE9101431L (sv) | Foerfarande foer framstaellning av furo-(3,4-c)-pyriinderivat i ickeracemisk form | |
ES2147196T3 (es) | Procedimiento para la hidrolisis estereoespecifica de derivados de piperidindiona. | |
ATE56472T1 (de) | Verfahren zur herstellung aromatisch substituierter l-aminosaeuren. | |
DE59106876D1 (de) | Verfahren zur enzymatischen Herstellung optisch aktiver Cyanhydrine. | |
DE69112716D1 (de) | Verfahren zur biologischen Herstellung einer Hydroxyvitamin-D-Verbindung. | |
ATE134706T1 (de) | Verfahren zur herstellung von 2- alkansäureenantiomeren | |
DE59009580D1 (de) | Verfahren zur racemattrennung von 4-aryl-2-oxo-pyrrolidin-3-carbonsäure-estern. | |
DE68912236D1 (de) | Verfahren zur Herstellung von hochgradig ungesättigten Fettsäuren. | |
EP0289804A3 (de) | Verfahren zur Herstellung von optisch aktiven Mercapto-Verbindungen | |
ATE85084T1 (de) | Racematspaltung von 7 alpha-acyloxy-6 betahydroxy-methyl-2-oxabicyclo 3.3.0 octan-3-onen durch stereospezifische enzymatische acylat- hydrolyse. | |
ATE76662T1 (de) | Enzymatisches verfahren zur herstellung von 3substituierten cephalosporinen. | |
ATE42203T1 (de) | Semi-synthetisches verfahren zur herstellung von insulin. | |
KR890003955A (ko) | 광학 활성 인-함유 작용성 아세트산 유도체의 효소적 제조방밥 | |
AU585703B2 (en) | Process for the enzymatic resolution of racemic 2-amino- 1-alkanols | |
ATE1553T1 (de) | Verfahren zur herstellung von penizillinderivaten. | |
DE3460566D1 (en) | Process for the preparation of the optic antipodes of tertiary leucine | |
ATE16696T1 (de) | Verfahren zur herstellung von 3-alkyl-6-methylbeta-resorcylsaeureestern. | |
JPS56121492A (en) | Preparation of l-phenylalanine |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |