ATE403740T1 - Verfahren, werkzeuge und reagenzien für zelltrennung - Google Patents

Verfahren, werkzeuge und reagenzien für zelltrennung

Info

Publication number
ATE403740T1
ATE403740T1 AT99939479T AT99939479T ATE403740T1 AT E403740 T1 ATE403740 T1 AT E403740T1 AT 99939479 T AT99939479 T AT 99939479T AT 99939479 T AT99939479 T AT 99939479T AT E403740 T1 ATE403740 T1 AT E403740T1
Authority
AT
Austria
Prior art keywords
cells
cell separation
reagents
tools
methods
Prior art date
Application number
AT99939479T
Other languages
English (en)
Inventor
De Saint Julien Jean- Bisconte
Patrizia Paterlini
Original Assignee
Inst Nat Sante Rech Med
Assist Publ Hopitaux De Paris
Univ Paris Descartes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med, Assist Publ Hopitaux De Paris, Univ Paris Descartes filed Critical Inst Nat Sante Rech Med
Application granted granted Critical
Publication of ATE403740T1 publication Critical patent/ATE403740T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761Hepatitis B
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99939479T 1998-08-25 1999-08-23 Verfahren, werkzeuge und reagenzien für zelltrennung ATE403740T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9810696A FR2782730B1 (fr) 1998-08-25 1998-08-25 Procede de separation cellulaire pour l'isolation de cellules pathogeniques, notamment cancereuses rares, equipement et reactif pour la mise en oeuvre du procede et application du procede

Publications (1)

Publication Number Publication Date
ATE403740T1 true ATE403740T1 (de) 2008-08-15

Family

ID=9529872

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99939479T ATE403740T1 (de) 1998-08-25 1999-08-23 Verfahren, werkzeuge und reagenzien für zelltrennung

Country Status (8)

Country Link
US (1) US7316897B2 (de)
EP (1) EP1108057B1 (de)
AT (1) ATE403740T1 (de)
AU (1) AU5376299A (de)
DE (1) DE69939265D1 (de)
ES (1) ES2312213T3 (de)
FR (1) FR2782730B1 (de)
WO (1) WO2000011210A1 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2824144B1 (fr) 2001-04-30 2004-09-17 Metagenex S A R L Methode de diagnostic prenatal sur cellule foetale isolee du sang maternel
US7393656B2 (en) * 2001-07-10 2008-07-01 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for risk stratification
US7381535B2 (en) 2002-07-10 2008-06-03 The Board Of Trustees Of The Leland Stanford Junior Methods and compositions for detecting receptor-ligand interactions in single cells
ATE441857T1 (de) 2001-07-10 2009-09-15 Univ Leland Stanford Junior Verfahren und zusammensetzungen zum nachweis des aktivierungszustands multipler proteine in einzelzellen
WO2003008931A2 (en) 2001-07-17 2003-01-30 Georgi Hvichia Microstructure for particle and cell separation, identification, sorting, and manipulation
CA2500392C (en) * 2002-09-27 2012-11-27 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
EP1604184A4 (de) * 2003-02-27 2010-10-27 Stephen A Lesko Standardisierte bewertung von therapeutischer wirksamkeit auf basis zellulärer biomarker
JP2007503597A (ja) * 2003-06-13 2007-02-22 ザ ジェネラル ホスピタル コーポレーション 血液から赤血球および血小板をサイズに基づいて除去するための微少流体システム
AU2005218622A1 (en) * 2004-03-03 2005-09-15 Living Microsystems Magnetic device for isolation of cells and biomolecules in a microfluidic environment
FR2880897B1 (fr) * 2005-01-18 2010-12-17 Inst Nat Sante Rech Med Methode de detection, non invasive, prenatale, in vitro de l'etat sain normal, de l'etat de porteur sain ou de l'etat de porteur malade de la mucoviscidose
FR2883488B1 (fr) * 2005-03-24 2010-12-10 Inst Nat Sante Rech Med Procede et dispositif pour separer par filtration verticale des particules biologiques contenues dans un liquide
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8921102B2 (en) * 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US20080070792A1 (en) * 2006-06-14 2008-03-20 Roland Stoughton Use of highly parallel snp genotyping for fetal diagnosis
US20080050739A1 (en) * 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
EP2589668A1 (de) 2006-06-14 2013-05-08 Verinata Health, Inc Analyse seltener Zellen mittels Probentrennung und DNA-Etiketten
WO2007147018A1 (en) * 2006-06-14 2007-12-21 Cellpoint Diagnostics, Inc. Analysis of rare cell-enriched samples
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
FR2926090B1 (fr) * 2008-01-09 2012-04-27 Metagenex Procede et dispositif pour isoler et cultiver des cellules vivantes sur un filtre.
US20090269800A1 (en) * 2008-04-29 2009-10-29 Todd Covey Device and method for processing cell samples
EP2304436A1 (de) 2008-07-10 2011-04-06 Nodality, Inc. Diagnose-, prognose- und behandlungsverfahren
US20100014741A1 (en) * 2008-07-10 2010-01-21 Banville Steven C Methods and apparatus related to gate boundaries within a data space
GB2474613A (en) * 2008-07-10 2011-04-20 Nodality Inc Methods and apparatus related to management of experiments
US9183237B2 (en) 2008-07-10 2015-11-10 Nodality, Inc. Methods and apparatus related to gate boundaries within a data space
EP3751005A3 (de) 2008-09-20 2021-02-24 The Board of Trustees of the Leland Stanford Junior University Nicht invasive diagnose von fötaler aneuploidie durch sequenzierung
US20100099109A1 (en) * 2008-10-17 2010-04-22 Nodality, Inc., A Delaware Corporation Methods for Analyzing Drug Response
US9034257B2 (en) * 2008-10-27 2015-05-19 Nodality, Inc. High throughput flow cytometry system and method
US8309306B2 (en) * 2008-11-12 2012-11-13 Nodality, Inc. Detection composition
US20100209929A1 (en) * 2009-01-14 2010-08-19 Nodality, Inc., A Delaware Corporation Multiple mechanisms for modulation of jak/stat activity
US20100204973A1 (en) * 2009-01-15 2010-08-12 Nodality, Inc., A Delaware Corporation Methods For Diagnosis, Prognosis And Treatment
US20100233733A1 (en) * 2009-02-10 2010-09-16 Nodality, Inc., A Delaware Corporation Multiple mechanisms for modulation of the pi3 kinase pathway
US20100215644A1 (en) * 2009-02-25 2010-08-26 Nodality, Inc. A Delaware Corporation Analysis of nodes in cellular pathways
US9459246B2 (en) 2009-09-08 2016-10-04 Nodality, Inc. Induced intercellular communication
HUE052213T2 (hu) 2009-11-06 2021-04-28 Univ Leland Stanford Junior Grafitkilökõdés nem invazív diagnosztizálása szervátültetett betegekben
US20110152112A1 (en) * 2009-12-23 2011-06-23 Artery Therapeutics, Inc. Diagnosis and treatment of reverse cholesterol transport deficiency-related diseases
US9404864B2 (en) 2013-03-13 2016-08-02 Denovo Sciences, Inc. System for imaging captured cells
US10466160B2 (en) 2011-08-01 2019-11-05 Celsee Diagnostics, Inc. System and method for retrieving and analyzing particles
EP2739587B1 (de) 2011-08-01 2020-05-27 Denovo Sciences Zellerfassungssystem
US9174216B2 (en) 2013-03-13 2015-11-03 DeNovo Science, Inc. System for capturing and analyzing cells
DE102013209718B4 (de) * 2012-06-22 2015-09-10 Human Med Ag Vorrichtung zum Separieren von adulten Stammzellen
US9606102B2 (en) 2013-01-26 2017-03-28 Denovo Sciences, Inc. System and method for capturing and analyzing cells
US9707562B2 (en) 2013-03-13 2017-07-18 Denovo Sciences, Inc. System for capturing and analyzing cells
WO2014144822A2 (en) 2013-03-15 2014-09-18 Immumetrix, Inc. Methods and compositions for tagging and analyzing samples
US10391490B2 (en) 2013-05-31 2019-08-27 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
US9856535B2 (en) 2013-05-31 2018-01-02 Denovo Sciences, Inc. System for isolating cells
FR3012974B1 (fr) 2013-11-12 2016-01-15 Biocarecell Dispositif a filtration amelioree pour retenir des cellules contenues dans un echantillon liquide.
EP4039367A1 (de) 2017-08-29 2022-08-10 Bio-Rad Laboratories, Inc. System und verfahren zum isolieren und analysieren von zellen
US10633693B1 (en) 2019-04-16 2020-04-28 Celsee Diagnostics, Inc. System and method for leakage control in a particle capture system
US11273439B2 (en) 2019-05-07 2022-03-15 Bio-Rad Laboratories, Inc. System and method for target material retrieval from microwells
JP7413408B2 (ja) 2019-05-07 2024-01-15 バイオ-ラッド ラボラトリーズ インコーポレイテッド 自動化された単一細胞処理のためのシステムおよび方法
CN114302643B (zh) 2019-06-14 2024-02-27 伯乐实验室有限公司 用于自动化单细胞处理和分析的***和方法
US11504719B2 (en) 2020-03-12 2022-11-22 Bio-Rad Laboratories, Inc. System and method for receiving and delivering a fluid for sample processing

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1561577A (en) * 1977-02-24 1980-02-27 Sanki Eng Co Ltd Cell fragility testing
US5070014A (en) * 1982-09-30 1991-12-03 Wadley Technologies, Inc. Stabilization of specimens for microbial analysis
US4937187A (en) * 1983-02-04 1990-06-26 Brown University Research Foundation Methods for separating malignant cells from clinical specimens
US4581331A (en) * 1983-09-29 1986-04-08 E. I. Du Pont De Nemours And Company Method for the rapid detection of virus and viral antigens
US4751179A (en) * 1984-05-31 1988-06-14 Coulter Electronics, Inc. Method and reagents for differential determination of four populations of leukocytes in blood
US5057413A (en) * 1988-06-13 1991-10-15 Becton, Dickinson And Company Method for discriminating between intact and damaged cells in a sample
AU6517890A (en) * 1989-09-20 1991-04-18 Cell Biotech, Inc. Cell separation invention
US5498336A (en) * 1991-02-22 1996-03-12 Terumo Kabushiki Kaisha Leukocyte-removing filter and leukocyte-removing apparatus furnished therewith
DK0667920T3 (da) * 1992-10-29 2003-04-14 Univ Jefferson Fremgangsmåder til påvisning af prostatacancermetastase
US5532139A (en) * 1992-10-30 1996-07-02 Micro-Med, Inc. Micro lysis-analysis process to measure cell characteristics and diagnose diseases
ES2284160T3 (es) * 1993-02-25 2007-11-01 Abbott Laboratories Sistema reactivo multiuso capaz de lisar rapidamente muestras de sangre completa.
NO180658C (no) * 1994-03-10 1997-05-21 Oeystein Fodstad Fremgangsmåte og anordning for deteksjon av spesifikke målceller i spesialiserte eller blandede cellepopulasjoner og opplösninger som inneholder blandede cellepopulasjoner
US5648222A (en) * 1994-07-27 1997-07-15 The Trustees Of Columbia University In The City Of New York Method for preserving cells, and uses of said method
JP3322595B2 (ja) * 1996-03-28 2002-09-09 テルモ株式会社 フィルター装置および生体微細組織の分離・回収方法
US6190855B1 (en) * 1996-10-28 2001-02-20 Baxter International Inc. Systems and methods for removing viral agents from blood
KR100399475B1 (ko) * 1998-02-12 2003-09-29 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 순환 중인 암세포의 신속하고 효과적인 분리 방법 및 이를위한 제제

Also Published As

Publication number Publication date
US20020028431A1 (en) 2002-03-07
DE69939265D1 (de) 2008-09-18
WO2000011210A1 (fr) 2000-03-02
FR2782730A1 (fr) 2000-03-03
EP1108057A1 (de) 2001-06-20
FR2782730B1 (fr) 2002-05-17
EP1108057B1 (de) 2008-08-06
US7316897B2 (en) 2008-01-08
ES2312213T3 (es) 2009-02-16
AU5376299A (en) 2000-03-14

Similar Documents

Publication Publication Date Title
ATE403740T1 (de) Verfahren, werkzeuge und reagenzien für zelltrennung
DE19681033D2 (de) Verfahren zur Quantifizierung von Tumorzellen in einer Körperflüssigkeit und dazu geeignete Testkits
ATE179425T1 (de) Verfahren zur abreicherung oder entfernung von endotoxinen
DE60008252D1 (de) Verfahren zum aufbereiten von kärschlamm
DE69427103T2 (de) Verfahren, Reagenzien und Kits zur Untersuchung von Neisseria gonorrhoeae und Chlamydia trachomatis
DE69006464D1 (de) An inorganischen Trägern gebundene, Pyridin enthaltende Alkoxysilane und Verfahren zu deren Verwendung zur Beseitigung und Konzentrierung von gewünschten Ionen in Flüssigkeiten.
ATE3726T1 (de) Verfahren und diagnostische mittel zum nachweis von redox-reaktionen.
ATE91708T1 (de) Verfahren zur freisetzung von rns und dns aus zellen.
DE60137203D1 (de) Poröse ferro- oder ferrimagnetische glasteilchen für molekültrennung
HK1018080A1 (en) Process for direct sequencing during template amplification
ATE373105T1 (de) Verbindungen und methoden zum nachweis von biomolekülen
DE3366371D1 (en) Method for the specific determination of cholesterol of the ldl fraction in serum
JP2003511021A5 (de)
ATE133206T1 (de) Verfahren zum nachweis von bakterien im harn
CU23095A1 (es) Proceso para la tipificación rápida de microorganismos y juego de reactivos empleado
DE60043775D1 (de) Verfahren zum identifizieren von präneoplastischen und neoplastischen stadien in säugern
ATE221657T1 (de) Entstörung durch rheumafaktoren
ATE13558T1 (de) Mittel und verfahren zum nachweis von wasserstoffperoxid.
PT82940A (de) Mit uberzugen versehene formkorper zur bindung von bioaffinen substanzen verfahren zu ihrer herstellung sowie ihre verwendung
DE60140563D1 (de) Verfahren und zusammensetzungen zum aussortieren und/oder nachweis von mikroorganismen
DE3765147D1 (de) Verfahren und reagenz zur bestimmung von gesamt-bilirubin.
ATE380584T1 (de) Hybridverfahren zur herstellung von trägern für die analytbestimmung
ATE225859T1 (de) Nachweis von antibiotikumresistenzen in mikroorganismen
ATE424446T1 (de) Zur oxidation von arsen verwendbare bakterien, verfahren zu ihrer selektion und ihre verwendung zur aufbereitung von arsenhaltigen medien
ATE132896T1 (de) Methoden zur verwendung von an humanen klasse-ii- histokompatibilitätsantigenen mangelnden zellinien

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1108057

Country of ref document: EP