ATE403432T1 - Pharmazeutische darreichungsform mit gesteuerter freigabe eines cholesterylester- transferproteininhibitors - Google Patents

Pharmazeutische darreichungsform mit gesteuerter freigabe eines cholesterylester- transferproteininhibitors

Info

Publication number
ATE403432T1
ATE403432T1 AT03700414T AT03700414T ATE403432T1 AT E403432 T1 ATE403432 T1 AT E403432T1 AT 03700414 T AT03700414 T AT 03700414T AT 03700414 T AT03700414 T AT 03700414T AT E403432 T1 ATE403432 T1 AT E403432T1
Authority
AT
Austria
Prior art keywords
dosage form
controlled release
pharmaceutical dosage
transfer protein
protein inhibitor
Prior art date
Application number
AT03700414T
Other languages
English (en)
Inventor
William John Curatolo
Steven Charles Sutton
Leah Elizabeth Appel
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of ATE403432T1 publication Critical patent/ATE403432T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
AT03700414T 2002-02-01 2003-01-20 Pharmazeutische darreichungsform mit gesteuerter freigabe eines cholesterylester- transferproteininhibitors ATE403432T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35371902P 2002-02-01 2002-02-01

Publications (1)

Publication Number Publication Date
ATE403432T1 true ATE403432T1 (de) 2008-08-15

Family

ID=27663244

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03700414T ATE403432T1 (de) 2002-02-01 2003-01-20 Pharmazeutische darreichungsform mit gesteuerter freigabe eines cholesterylester- transferproteininhibitors

Country Status (24)

Country Link
US (1) US20030198674A1 (de)
EP (1) EP1474144B1 (de)
JP (1) JP2005522424A (de)
KR (1) KR20040083493A (de)
CN (1) CN1625397A (de)
AR (1) AR038385A1 (de)
AT (1) ATE403432T1 (de)
BR (1) BR0307332A (de)
CA (1) CA2473991C (de)
DE (1) DE60322665D1 (de)
ES (1) ES2309294T3 (de)
GT (1) GT200300023A (de)
HN (1) HN2003000054A (de)
IL (1) IL162870A0 (de)
MX (1) MXPA04005647A (de)
NO (1) NO20043506L (de)
PA (1) PA8565101A1 (de)
PE (1) PE20030806A1 (de)
PL (1) PL371416A1 (de)
RU (1) RU2004123637A (de)
TW (1) TW200303204A (de)
UY (1) UY27643A1 (de)
WO (1) WO2003063868A1 (de)
ZA (1) ZA200404718B (de)

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Also Published As

Publication number Publication date
PE20030806A1 (es) 2003-09-19
TW200303204A (en) 2003-09-01
IL162870A0 (en) 2005-11-20
AR038385A1 (es) 2005-01-12
CA2473991C (en) 2009-09-15
EP1474144A1 (de) 2004-11-10
PL371416A1 (en) 2005-06-13
PA8565101A1 (es) 2003-11-12
US20030198674A1 (en) 2003-10-23
ES2309294T3 (es) 2008-12-16
NO20043506L (no) 2004-10-19
WO2003063868A1 (en) 2003-08-07
UY27643A1 (es) 2003-08-29
KR20040083493A (ko) 2004-10-02
CN1625397A (zh) 2005-06-08
RU2004123637A (ru) 2005-04-20
CA2473991A1 (en) 2003-08-07
DE60322665D1 (de) 2008-09-18
JP2005522424A (ja) 2005-07-28
MXPA04005647A (es) 2005-03-23
BR0307332A (pt) 2004-12-07
EP1474144B1 (de) 2008-08-06
HN2003000054A (es) 2003-11-24
ZA200404718B (en) 2006-11-29
GT200300023A (es) 2003-09-17

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