ATE402947T1 - Verfahren und vorrichtung zur kontinuierlichen radioaktiven markierung von proteinen im grossen massstab - Google Patents

Verfahren und vorrichtung zur kontinuierlichen radioaktiven markierung von proteinen im grossen massstab

Info

Publication number
ATE402947T1
ATE402947T1 AT04785799T AT04785799T ATE402947T1 AT E402947 T1 ATE402947 T1 AT E402947T1 AT 04785799 T AT04785799 T AT 04785799T AT 04785799 T AT04785799 T AT 04785799T AT E402947 T1 ATE402947 T1 AT E402947T1
Authority
AT
Austria
Prior art keywords
proteins
large scale
radioactive labeling
continuous
continuous radioactive
Prior art date
Application number
AT04785799T
Other languages
English (en)
Inventor
Raimo Pellikka
Steven King
Peter Blaeuenstein
Pius Schubiger
Original Assignee
Peregrine Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peregrine Pharmaceuticals Inc filed Critical Peregrine Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE402947T1 publication Critical patent/ATE402947T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13—Labelling of peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34—Size selective separation, e.g. size exclusion chromatography, gel filtration, permeation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/496—Multiperforated metal article making
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT04785799T 2003-06-25 2004-06-25 Verfahren und vorrichtung zur kontinuierlichen radioaktiven markierung von proteinen im grossen massstab ATE402947T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48238703P 2003-06-25 2003-06-25
US49312103P 2003-08-07 2003-08-07
US49368903P 2003-08-08 2003-08-08

Publications (1)

Publication Number Publication Date
ATE402947T1 true ATE402947T1 (de) 2008-08-15

Family

ID=33568598

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04785799T ATE402947T1 (de) 2003-06-25 2004-06-25 Verfahren und vorrichtung zur kontinuierlichen radioaktiven markierung von proteinen im grossen massstab

Country Status (10)

Country Link
US (2) US7591953B2 (de)
EP (2) EP1964847A3 (de)
AT (1) ATE402947T1 (de)
AU (1) AU2004253924B2 (de)
CA (1) CA2527054C (de)
DE (1) DE602004015454D1 (de)
DK (1) DK1638989T3 (de)
HK (1) HK1087417A1 (de)
NZ (1) NZ543495A (de)
WO (1) WO2005003151A2 (de)

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ATE402947T1 (de) * 2003-06-25 2008-08-15 Peregrine Pharmaceuticals Inc Verfahren und vorrichtung zur kontinuierlichen radioaktiven markierung von proteinen im grossen massstab
GB0520527D0 (en) * 2005-10-10 2005-11-16 Ge Healthcare Ltd Automated method
WO2009058737A1 (en) * 2007-10-29 2009-05-07 Pain Therapeutics, Inc. Disposable column system for purification of radiolabeled polypeptides
ITBO20080236A1 (it) * 2008-04-17 2009-10-18 Philogen Spa Apparecchiatura e metodo per la preparazione di medicinali contenenti sostanze radioattive.
US9540607B2 (en) * 2011-02-22 2017-01-10 Cytonet, Llc Fill system for providing uniform concentrations and volumes and methods thereof
EP2766467A1 (de) * 2011-10-10 2014-08-20 DASGIP Information and Process Technology GmbH Biotechnologische vorrichtung mit einem bioreaktor, abgassteuerungsvorrichtung für einen bioreaktor und verfahren zur behandlung eines abgasstroms in einer biotechnologischen vorrichtung
DE102012209852A1 (de) 2012-06-12 2013-12-12 Robert Bosch Gmbh Abgasreinigungssystem zur Anordnung in einem Abgasstrang eines Kraftfahrzeuges, insbesondere eines Dieselkraftfahrzeugs
US20140329319A1 (en) * 2013-05-02 2014-11-06 Canadian Blood Services Apparatus and method for the immunocamouflage of biological cells
US10829423B2 (en) 2014-06-18 2020-11-10 Alpha Therapy Solutions Ab Automatic process platform for the production of astatine-211 [At 211] radiopharmaceuticals

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US4472371A (en) * 1979-10-29 1984-09-18 Summa Medical Corporation Radiolabeled antibody to anti-tumor associated antigen and process
US4362699A (en) * 1981-03-10 1982-12-07 Bio Research, Inc. Apparatus for high pressure peptide synthesis
US4401646A (en) * 1981-05-08 1983-08-30 University Patents Inc. Method and apparatus for purifying materials radiolabeled with technetium-99m
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US4861581A (en) 1986-12-05 1989-08-29 Cancer Biologics, Inc. Detection of necrotic malignant tissue and associated therapy
DE3705686C2 (de) * 1987-02-23 1995-11-30 Boehringer Mannheim Gmbh Verfahren zur Bestimmung von Antikörpern
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US5206346A (en) * 1990-12-05 1993-04-27 E. I. Du Pont De Nemours And Company Method for iodination/purification
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CA2108017C (en) * 1991-05-01 2004-07-20 Charles Philip Wells Method of conveying liquid materials and device for the automated elution of a radionuclide generator
US5877289A (en) 1992-03-05 1999-03-02 The Scripps Research Institute Tissue factor compositions and ligands for the specific coagulation of vasculature
US5660827A (en) 1992-03-05 1997-08-26 Board Of Regents, The University Of Texas System Antibodies that bind to endoglin
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ATE402947T1 (de) * 2003-06-25 2008-08-15 Peregrine Pharmaceuticals Inc Verfahren und vorrichtung zur kontinuierlichen radioaktiven markierung von proteinen im grossen massstab

Also Published As

Publication number Publication date
DK1638989T3 (da) 2008-11-17
WO2005003151A3 (en) 2005-04-07
EP1964847A2 (de) 2008-09-03
DE602004015454D1 (de) 2008-09-11
HK1087417A1 (en) 2006-10-13
CA2527054C (en) 2013-01-08
EP1638989B1 (de) 2008-07-30
AU2004253924B2 (en) 2009-07-30
US7591953B2 (en) 2009-09-22
NZ543495A (en) 2009-04-30
US20090312523A1 (en) 2009-12-17
US20050123474A1 (en) 2005-06-09
EP1964847A3 (de) 2008-09-17
AU2004253924A1 (en) 2005-01-13
CA2527054A1 (en) 2005-01-13
EP1638989A2 (de) 2006-03-29
WO2005003151A2 (en) 2005-01-13
US8137540B2 (en) 2012-03-20

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