ATE394492T1 - Verfahren zur oligomerisation von peptiden - Google Patents
Verfahren zur oligomerisation von peptidenInfo
- Publication number
- ATE394492T1 ATE394492T1 AT97948802T AT97948802T ATE394492T1 AT E394492 T1 ATE394492 T1 AT E394492T1 AT 97948802 T AT97948802 T AT 97948802T AT 97948802 T AT97948802 T AT 97948802T AT E394492 T1 ATE394492 T1 AT E394492T1
- Authority
- AT
- Austria
- Prior art keywords
- oligomerization
- peptides
- oligomer
- oligomerizing
- domain
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 238000006384 oligomerization reaction Methods 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 230000003606 oligomerizing effect Effects 0.000 abstract 2
- 102000008394 Immunoglobulin Fragments Human genes 0.000 abstract 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96810719 | 1996-10-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE394492T1 true ATE394492T1 (de) | 2008-05-15 |
Family
ID=8225734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97948802T ATE394492T1 (de) | 1996-10-28 | 1997-10-24 | Verfahren zur oligomerisation von peptiden |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100105876A1 (de) |
| EP (1) | EP0938571B8 (de) |
| AT (1) | ATE394492T1 (de) |
| AU (1) | AU6909298A (de) |
| DE (1) | DE69738670D1 (de) |
| ES (1) | ES2309999T3 (de) |
| WO (1) | WO1998018943A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6160088A (en) * | 1998-07-29 | 2000-12-12 | Sloan-Kettering Institute For Cancer | KDEL receptor inhibitors |
| EP1149168A2 (de) * | 1999-02-01 | 2001-10-31 | Beth Israel Deaconess Medical Center | Comp/tsp-1, comp/tsp-2 und andere chimerische proteinen |
| AU4933200A (en) * | 1999-05-14 | 2000-12-05 | Medical Research Council | Oligomeric chaperone proteins |
| WO2000069907A1 (en) * | 1999-05-14 | 2000-11-23 | Medical Research Council | Protein scaffold and its use to multimerise monomeric polypeptides |
| WO2002070725A1 (en) * | 2001-03-06 | 2002-09-12 | Mustapha Abdelouahed | Carrier chimeric proteins, targeted carrier chimeric proteins and preparation thereof |
| MXPA04005134A (es) * | 2001-11-30 | 2004-08-11 | Ca Nat Research Council | Novedosas moleculas de auto-montaje. |
| US20060233808A1 (en) * | 2003-04-04 | 2006-10-19 | David Deperthes | Peptabody for cancer treatment |
| GB2408507B (en) * | 2003-10-06 | 2005-12-14 | Proimmune Ltd | Chimeric MHC protein and oligomer thereof for specific targeting |
| GB2409456B (en) * | 2003-10-30 | 2006-01-04 | Proimmune Ltd | Oligomeric receptor ligand pair member complexes |
| WO2007059007A2 (en) | 2005-11-14 | 2007-05-24 | Cythera, Inc. | Markers of definitive endoderm |
| US20050266554A1 (en) | 2004-04-27 | 2005-12-01 | D Amour Kevin A | PDX1 expressing endoderm |
| EA200601231A1 (ru) | 2003-12-23 | 2007-06-29 | Китера, Инк. | Дефинитивная энтодерма |
| US7985585B2 (en) | 2004-07-09 | 2011-07-26 | Viacyte, Inc. | Preprimitive streak and mesendoderm cells |
| US7625753B2 (en) | 2003-12-23 | 2009-12-01 | Cythera, Inc. | Expansion of definitive endoderm cells |
| US8647873B2 (en) | 2004-04-27 | 2014-02-11 | Viacyte, Inc. | PDX1 expressing endoderm |
| MX2007001772A (es) | 2004-08-13 | 2007-07-11 | Univ Georgia Res Found | Composiciones y metodos para auto-renovacion y diferenciacion de celulas troncales embrionicas humanas. |
| US7989204B2 (en) | 2006-04-28 | 2011-08-02 | Viacyte, Inc. | Hepatocyte lineage cells |
| US7695963B2 (en) | 2007-09-24 | 2010-04-13 | Cythera, Inc. | Methods for increasing definitive endoderm production |
| AR068767A1 (es) | 2007-10-12 | 2009-12-02 | Novartis Ag | Anticuerpos contra esclerostina, composiciones y metodos de uso de estos anticuerpos para tratar un trastorno patologico mediado por esclerostina |
| RS54113B1 (en) | 2008-08-05 | 2015-12-31 | Novartis Ag | COMPOSITIONS AND PROCEDURES FOR ANTIBODIES ON THE C5 COMPLEMENTARY PROTEIN |
| WO2010103475A2 (en) | 2009-03-10 | 2010-09-16 | Med Discovery Sa | Use of serine protease inhibitors in the treatment of neutropenia |
| WO2010102518A1 (zh) * | 2009-03-13 | 2010-09-16 | 北京表源生物技术有限公司 | 一种融合蛋白多聚体 |
| CN104725512A (zh) | 2009-04-27 | 2015-06-24 | 诺华股份有限公司 | 增加肌肉生长的组合物和方法 |
| WO2011029823A1 (en) | 2009-09-09 | 2011-03-17 | Novartis Ag | Monoclonal antibody reactive with cd63 when expressed at the surface of degranulated mast cells |
| ES2692519T3 (es) | 2011-07-01 | 2018-12-04 | Novartis Ag | Método para tratar trastornos metabólicos |
| EP3851454A1 (de) | 2012-12-05 | 2021-07-21 | Novartis AG | Zusammensetzungen und verfahren für gegen epo gerichtete antikörper |
| EP3033358A2 (de) | 2013-08-14 | 2016-06-22 | Novartis AG | Verfahren zur behandlung sporadischer einschlusskörper-myositis |
| TW201622746A (zh) | 2014-04-24 | 2016-07-01 | 諾華公司 | 改善或加速髖部骨折術後身體復原之方法 |
| WO2018175460A1 (en) | 2017-03-24 | 2018-09-27 | Novartis Ag | Methods for preventing and treating heart disease |
| JP2020511992A (ja) * | 2017-03-29 | 2020-04-23 | サニーブルック リサーチ インスティテュート | 遺伝子組換えｔ細胞調節分子およびその使用方法 |
| EP3704150A1 (de) * | 2017-11-01 | 2020-09-09 | F. Hoffmann-La Roche AG | Compbody ein multivalentes zielbindemittel |
| CN115232205A (zh) * | 2022-08-03 | 2022-10-25 | 南京京达生物技术有限公司 | 一种鼠源IgM亚型单克隆抗体纯化方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2207195A (en) * | 1994-04-05 | 1995-10-23 | Board Of Regents, The University Of Texas System | Modified receptors that continuously signal |
| GB9409768D0 (en) * | 1994-05-16 | 1994-07-06 | Medical Res Council | Trimerising polypeptides |
| EP0827544B1 (de) * | 1995-05-23 | 2004-08-18 | MorphoSys AG | Multimere proteine |
-
1997
- 1997-10-24 DE DE69738670T patent/DE69738670D1/de not_active Expired - Lifetime
- 1997-10-24 AT AT97948802T patent/ATE394492T1/de not_active IP Right Cessation
- 1997-10-24 ES ES97948802T patent/ES2309999T3/es not_active Expired - Lifetime
- 1997-10-24 AU AU69092/98A patent/AU6909298A/en not_active Abandoned
- 1997-10-24 EP EP97948802A patent/EP0938571B8/de not_active Expired - Lifetime
- 1997-10-24 WO PCT/EP1997/005897 patent/WO1998018943A1/en active IP Right Grant
-
2002
- 2002-04-25 US US10/132,533 patent/US20100105876A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU6909298A (en) | 1998-05-22 |
| WO1998018943A1 (en) | 1998-05-07 |
| ES2309999T3 (es) | 2008-12-16 |
| US20100105876A1 (en) | 2010-04-29 |
| EP0938571B8 (de) | 2008-07-02 |
| DE69738670D1 (de) | 2008-06-19 |
| EP0938571A1 (de) | 1999-09-01 |
| EP0938571B1 (de) | 2008-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |