ATE391474T1 - Gelenkige wirbelscheibenprothese - Google Patents
Gelenkige wirbelscheibenprotheseInfo
- Publication number
- ATE391474T1 ATE391474T1 AT04702362T AT04702362T ATE391474T1 AT E391474 T1 ATE391474 T1 AT E391474T1 AT 04702362 T AT04702362 T AT 04702362T AT 04702362 T AT04702362 T AT 04702362T AT E391474 T1 ATE391474 T1 AT E391474T1
- Authority
- AT
- Austria
- Prior art keywords
- bearing surface
- vertebra
- disc prosthesis
- lower member
- upper member
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
- A61F2/4425—Intervertebral or spinal discs, e.g. resilient made of articulated components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2/4611—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30621—Features concerning the anatomical functioning or articulation of the prosthetic joint
- A61F2002/30649—Ball-and-socket joints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30621—Features concerning the anatomical functioning or articulation of the prosthetic joint
- A61F2002/30649—Ball-and-socket joints
- A61F2002/30654—Details of the concave socket
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30621—Features concerning the anatomical functioning or articulation of the prosthetic joint
- A61F2002/30649—Ball-and-socket joints
- A61F2002/30654—Details of the concave socket
- A61F2002/30655—Non-spherical concave inner surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30621—Features concerning the anatomical functioning or articulation of the prosthetic joint
- A61F2002/30649—Ball-and-socket joints
- A61F2002/30662—Ball-and-socket joints with rotation-limiting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/30782—Apertures or holes, e.g. of circular cross section inclined obliquely
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/3079—Stepped or enlarged apertures, e.g. having discrete diameter changes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/3082—Grooves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/3082—Grooves
- A61F2002/30827—Plurality of grooves
- A61F2002/30828—Plurality of grooves parallel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30841—Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30878—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30878—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
- A61F2002/30891—Plurality of protrusions
- A61F2002/30892—Plurality of protrusions parallel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2002/30934—Special articulating surfaces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2002/4622—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof having the shape of a forceps or a clamp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2002/4625—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
- A61F2002/4628—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about an axis transverse to the instrument axis or to the implantation direction, e.g. clamping
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Prostheses (AREA)
- Manufacture Of Iron (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0301085.7A GB0301085D0 (en) | 2003-01-17 | 2003-01-17 | Articulating spinal disc prosthesis |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE391474T1 true ATE391474T1 (de) | 2008-04-15 |
Family
ID=9951317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04702362T ATE391474T1 (de) | 2003-01-17 | 2004-01-15 | Gelenkige wirbelscheibenprothese |
Country Status (7)
Country | Link |
---|---|
US (1) | US20060259147A1 (de) |
EP (1) | EP1587461B1 (de) |
AT (1) | ATE391474T1 (de) |
DE (1) | DE602004012960T2 (de) |
ES (1) | ES2303045T3 (de) |
GB (1) | GB0301085D0 (de) |
WO (1) | WO2004064692A2 (de) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7494507B2 (en) | 2000-01-30 | 2009-02-24 | Diamicron, Inc. | Articulating diamond-surfaced spinal implants |
NZ516410A (en) | 1999-07-02 | 2004-12-24 | Spine Solutions Inc | Intervertebral implant |
FR2846550B1 (fr) | 2002-11-05 | 2006-01-13 | Ldr Medical | Prothese de disque intervertebral |
US7753937B2 (en) | 2003-12-10 | 2010-07-13 | Facet Solutions Inc. | Linked bilateral spinal facet implants and methods of use |
PT1711133E (pt) | 2004-02-04 | 2011-06-01 | Ldr Medical | Prótese de disco intervertebral |
FR2865629B1 (fr) | 2004-02-04 | 2007-01-26 | Ldr Medical | Prothese de disque intervertebral |
US8353933B2 (en) | 2007-04-17 | 2013-01-15 | Gmedelaware 2 Llc | Facet joint replacement |
US8562649B2 (en) | 2004-02-17 | 2013-10-22 | Gmedelaware 2 Llc | System and method for multiple level facet joint arthroplasty and fusion |
FR2869528B1 (fr) * | 2004-04-28 | 2007-02-02 | Ldr Medical | Prothese de disque intervertebral |
US7507242B2 (en) | 2004-06-02 | 2009-03-24 | Facet Solutions | Surgical measurement and resection framework |
US9237958B2 (en) | 2004-06-30 | 2016-01-19 | Synergy Disc Replacement Inc. | Joint prostheses |
US8172904B2 (en) | 2004-06-30 | 2012-05-08 | Synergy Disc Replacement, Inc. | Artificial spinal disc |
US8100974B2 (en) | 2004-06-30 | 2012-01-24 | Synergy Disc Replacement, Inc. | Artificial spinal disc |
WO2006042485A1 (de) * | 2004-10-18 | 2006-04-27 | Buettner-Janz Karin | Bewegungsphysiologische bandscheibenendoprothese für die lenden- und halswirbelsäule |
WO2006042486A1 (de) | 2004-10-18 | 2006-04-27 | Buettner-Janz Karin | Bandscheibenendoprothese mit bewegungsadaptiertem rand für die lenden- und halswirbelsäule |
WO2006042484A1 (de) * | 2004-10-18 | 2006-04-27 | Buettner-Janz Karin | Gewinkelter gleitkern als teil einer bandscheibenendoprothese |
US7578848B2 (en) * | 2005-03-03 | 2009-08-25 | Cervical Xpand, Llc | Intervertebral stabilizer |
BRPI0608666A2 (pt) | 2005-04-06 | 2010-01-19 | Peter Mccombe | pràtese |
US7828828B2 (en) * | 2005-04-14 | 2010-11-09 | Warsaw Orthopedic, Inc | Intervertebral joint |
GB0508678D0 (en) * | 2005-04-28 | 2005-06-08 | Cope Aiden | Motion segment intervertebral disc prosthesis |
AU2006242416A1 (en) | 2005-05-02 | 2006-11-09 | Seaspine, Inc. | Motion restoring intervertebral device |
FR2891135B1 (fr) | 2005-09-23 | 2008-09-12 | Ldr Medical Sarl | Prothese de disque intervertebral |
KR101360188B1 (ko) * | 2005-11-04 | 2014-02-11 | 너바시브 인코퍼레이티드 | 보철물 구성요소의 장착 결함 저감방법 |
FR2893838B1 (fr) | 2005-11-30 | 2008-08-08 | Ldr Medical Soc Par Actions Si | Prothese de disque intervertebral et instrumentation d'insertion de la prothese entre les vertebres |
US20070173941A1 (en) * | 2006-01-25 | 2007-07-26 | Sdgi Holdings, Inc. | Intervertebral prosthetic disc and method of installing same |
US7806901B2 (en) * | 2006-03-17 | 2010-10-05 | Depuy Spine, Inc. | Arthroplasty final seating instruments |
CA2658876C (en) * | 2006-07-24 | 2015-03-17 | Spine Solutions, Inc. | Intervertebral implant with keel |
US7905919B2 (en) | 2006-11-07 | 2011-03-15 | Biomedflex Llc | Prosthetic joint |
US8512413B2 (en) | 2006-11-07 | 2013-08-20 | Biomedflex, Llc | Prosthetic knee joint |
US7914580B2 (en) | 2006-11-07 | 2011-03-29 | Biomedflex Llc | Prosthetic ball-and-socket joint |
US8308812B2 (en) | 2006-11-07 | 2012-11-13 | Biomedflex, Llc | Prosthetic joint assembly and joint member therefor |
US9005306B2 (en) | 2006-11-07 | 2015-04-14 | Biomedflex, Llc | Medical Implants With Compliant Wear-Resistant Surfaces |
US8029574B2 (en) | 2006-11-07 | 2011-10-04 | Biomedflex Llc | Prosthetic knee joint |
US9005307B2 (en) | 2006-11-07 | 2015-04-14 | Biomedflex, Llc | Prosthetic ball-and-socket joint |
US8070823B2 (en) | 2006-11-07 | 2011-12-06 | Biomedflex Llc | Prosthetic ball-and-socket joint |
US20110166671A1 (en) | 2006-11-07 | 2011-07-07 | Kellar Franz W | Prosthetic joint |
US9039768B2 (en) | 2006-12-22 | 2015-05-26 | Medos International Sarl | Composite vertebral spacers and instrument |
ES2605411T3 (es) | 2007-02-09 | 2017-03-14 | Dimicron, Inc. | Articulación de columna vertebral de múltiples lóbulos |
US8465546B2 (en) | 2007-02-16 | 2013-06-18 | Ldr Medical | Intervertebral disc prosthesis insertion assemblies |
AU2008316600B2 (en) | 2007-10-25 | 2014-09-18 | Jeffery D. Arnett | Systems and methods for vertebral disc replacement |
DE102007058304A1 (de) * | 2007-12-04 | 2009-06-10 | Global Medical Consulting Gmbh | Bandscheibenprothese |
US20090248092A1 (en) | 2008-03-26 | 2009-10-01 | Jonathan Bellas | Posterior Intervertebral Disc Inserter and Expansion Techniques |
US8936641B2 (en) | 2008-04-05 | 2015-01-20 | DePuy Synthes Products, LLC | Expandable intervertebral implant |
FR2929503B1 (fr) * | 2008-04-08 | 2011-04-29 | Kiscomedica | Prothese articulaire apte a etre implantee entre deux os |
DE102008032691A1 (de) * | 2008-07-03 | 2010-01-07 | Aesculap Ag | Bandscheibenprothesensystem |
US8187333B2 (en) | 2008-09-18 | 2012-05-29 | Mayer Peter L | Intervertebral disc prosthesis and method for implanting and explanting |
US8814937B2 (en) | 2008-09-18 | 2014-08-26 | Peter L. Mayer | Intervertebral disc prosthesis, method for assembling, method for implanting prosthesis, and method for explanting |
US9526620B2 (en) | 2009-03-30 | 2016-12-27 | DePuy Synthes Products, Inc. | Zero profile spinal fusion cage |
US9393129B2 (en) | 2009-12-10 | 2016-07-19 | DePuy Synthes Products, Inc. | Bellows-like expandable interbody fusion cage |
US8858636B2 (en) | 2010-04-09 | 2014-10-14 | DePuy Synthes Products, LLC | Intervertebral implant |
US9301853B2 (en) | 2010-04-09 | 2016-04-05 | DePuy Synthes Products, Inc. | Holder for implantation and extraction of prosthesis |
US11529241B2 (en) | 2010-09-23 | 2022-12-20 | DePuy Synthes Products, Inc. | Fusion cage with in-line single piece fixation |
US20120078372A1 (en) | 2010-09-23 | 2012-03-29 | Thomas Gamache | Novel implant inserter having a laterally-extending dovetail engagement feature |
US20120078373A1 (en) | 2010-09-23 | 2012-03-29 | Thomas Gamache | Stand alone intervertebral fusion device |
KR101297346B1 (ko) | 2011-04-01 | 2013-08-19 | 김희경 | 추간 인공 삽입물 |
WO2013033584A2 (en) * | 2011-09-01 | 2013-03-07 | In Queue Innovations, Llc | Disc replacement device and method of use |
US9248028B2 (en) | 2011-09-16 | 2016-02-02 | DePuy Synthes Products, Inc. | Removable, bone-securing cover plate for intervertebral fusion cage |
US8628578B2 (en) * | 2011-12-19 | 2014-01-14 | Warsaw Orthopedic, Inc. | Expandable interbody implant and methods of use |
US9271836B2 (en) | 2012-03-06 | 2016-03-01 | DePuy Synthes Products, Inc. | Nubbed plate |
US9393126B2 (en) | 2012-04-20 | 2016-07-19 | Peter L. Mayer | Bilaterally placed disc prosthesis for spinal implant and method of bilateral placement |
US9364339B2 (en) | 2012-04-30 | 2016-06-14 | Peter L. Mayer | Unilaterally placed expansile spinal prosthesis |
US10182921B2 (en) | 2012-11-09 | 2019-01-22 | DePuy Synthes Products, Inc. | Interbody device with opening to allow packing graft and other biologics |
US9522070B2 (en) | 2013-03-07 | 2016-12-20 | Interventional Spine, Inc. | Intervertebral implant |
US10940016B2 (en) | 2017-07-05 | 2021-03-09 | Medos International Sarl | Expandable intervertebral fusion cage |
US11439440B2 (en) * | 2019-06-30 | 2022-09-13 | Innovasis, Inc. | Vertebral disc repair |
US11452618B2 (en) | 2019-09-23 | 2022-09-27 | Dimicron, Inc | Spinal artificial disc removal tool |
US20220104949A1 (en) * | 2020-10-02 | 2022-04-07 | Facet Mobility, Llc | Artificial spinal prosthesis and method |
CN117653425A (zh) * | 2023-10-09 | 2024-03-08 | 北京爱康宜诚医疗器材有限公司 | 椎间假体及椎间假体组件 |
Family Cites Families (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2659226B1 (fr) * | 1990-03-07 | 1992-05-29 | Jbs Sa | Prothese pour disques intervertebraux et ses instruments d'implantation. |
GB9125798D0 (en) * | 1991-12-04 | 1992-02-05 | Customflex Limited | Improvements in or relating to spinal vertebrae implants |
US5425773A (en) * | 1992-01-06 | 1995-06-20 | Danek Medical, Inc. | Intervertebral disk arthroplasty device |
US5258031A (en) * | 1992-01-06 | 1993-11-02 | Danek Medical | Intervertebral disk arthroplasty |
DE4208115A1 (de) * | 1992-03-13 | 1993-09-16 | Link Waldemar Gmbh Co | Bandscheibenendoprothese |
DE4208116C2 (de) * | 1992-03-13 | 1995-08-03 | Link Waldemar Gmbh Co | Bandscheibenendoprothese |
US5676701A (en) * | 1993-01-14 | 1997-10-14 | Smith & Nephew, Inc. | Low wear artificial spinal disc |
DK1093760T3 (da) * | 1993-06-10 | 2005-03-29 | Karlin Technology Inc | Apparat til isætning af spinalimplantater |
FR2715293B1 (fr) * | 1994-01-26 | 1996-03-22 | Biomat | Cage intersomatique vertébrale. |
US5562736A (en) * | 1994-10-17 | 1996-10-08 | Raymedica, Inc. | Method for surgical implantation of a prosthetic spinal disc nucleus |
US5674296A (en) * | 1994-11-14 | 1997-10-07 | Spinal Dynamics Corporation | Human spinal disc prosthesis |
US5683465A (en) * | 1996-03-18 | 1997-11-04 | Shinn; Gary Lee | Artificial intervertebral disk prosthesis |
US5755796A (en) * | 1996-06-06 | 1998-05-26 | Ibo; Ivo | Prosthesis of the cervical intervertebralis disk |
US6835207B2 (en) * | 1996-07-22 | 2004-12-28 | Fred Zacouto | Skeletal implant |
US5782832A (en) * | 1996-10-01 | 1998-07-21 | Surgical Dynamics, Inc. | Spinal fusion implant and method of insertion thereof |
AU8768998A (en) * | 1997-08-04 | 1999-02-22 | Gordon, Maya, Roberts & Thomas Number 1 Llc | Multiple axis intervertebral prosthesis |
US5888226A (en) * | 1997-11-12 | 1999-03-30 | Rogozinski; Chaim | Intervertebral prosthetic disc |
US5899941A (en) * | 1997-12-09 | 1999-05-04 | Chubu Bearing Kabushiki Kaisha | Artificial intervertebral disk |
US6679915B1 (en) * | 1998-04-23 | 2004-01-20 | Sdgi Holdings, Inc. | Articulating spinal implant |
US6019792A (en) * | 1998-04-23 | 2000-02-01 | Cauthen Research Group, Inc. | Articulating spinal implant |
US6063121A (en) * | 1998-07-29 | 2000-05-16 | Xavier; Ravi | Vertebral body prosthesis |
ES2280106T3 (es) * | 1998-10-22 | 2007-09-01 | Warsaw Orthopedic, Inc. | Articulacion intervertebral artificial que permite movimientos de traslacion y de rotacion. |
US6113637A (en) * | 1998-10-22 | 2000-09-05 | Sofamor Danek Holdings, Inc. | Artificial intervertebral joint permitting translational and rotational motion |
US6039763A (en) * | 1998-10-27 | 2000-03-21 | Disc Replacement Technologies, Inc. | Articulating spinal disc prosthesis |
FR2787017B1 (fr) * | 1998-12-11 | 2001-04-27 | Dimso Sa | Prothese de disque intervertebral a comportement mecanique ameliore |
FR2787016B1 (fr) * | 1998-12-11 | 2001-03-02 | Dimso Sa | Prothese de disque intervertebral |
FR2787019B1 (fr) * | 1998-12-11 | 2001-03-02 | Dimso Sa | Prothese de disque intervertebral a comportement mecanique ameliore |
US6368350B1 (en) * | 1999-03-11 | 2002-04-09 | Sulzer Spine-Tech Inc. | Intervertebral disc prosthesis and method |
EP1057462B1 (de) * | 1999-05-21 | 2003-04-02 | Waldemar Link (GmbH & Co.) | Zwischenwirbel-Endoprothese mit einer gezahnten Anschlussplatte |
US6520996B1 (en) * | 1999-06-04 | 2003-02-18 | Depuy Acromed, Incorporated | Orthopedic implant |
NZ516410A (en) * | 1999-07-02 | 2004-12-24 | Spine Solutions Inc | Intervertebral implant |
FR2797179B1 (fr) * | 1999-08-03 | 2002-03-08 | Michel Gau | Prothese nucleaire intervertebrale et son procede chirurgical d'implantation |
US6878167B2 (en) * | 2002-04-24 | 2005-04-12 | Bret A. Ferree | Methods and apparatus for placing intradiscal devices |
US6830570B1 (en) * | 1999-10-21 | 2004-12-14 | Sdgi Holdings, Inc. | Devices and techniques for a posterior lateral disc space approach |
ES2298675T3 (es) * | 1999-10-22 | 2008-05-16 | Archus Orthopedics Inc. | Dispositivos de artroplastia facetaria. |
US8187303B2 (en) * | 2004-04-22 | 2012-05-29 | Gmedelaware 2 Llc | Anti-rotation fixation element for spinal prostheses |
US7014633B2 (en) * | 2000-02-16 | 2006-03-21 | Trans1, Inc. | Methods of performing procedures in the spine |
US6283968B1 (en) * | 2000-03-07 | 2001-09-04 | Hamid M. Mehdizadeh | Posterior laminectomy procedure |
FR2805985B1 (fr) * | 2000-03-10 | 2003-02-07 | Eurosurgical | Prothese de disque intervertebral |
US6402750B1 (en) * | 2000-04-04 | 2002-06-11 | Spinlabs, Llc | Devices and methods for the treatment of spinal disorders |
US6626905B1 (en) * | 2000-08-02 | 2003-09-30 | Sulzer Spine-Tech Inc. | Posterior oblique lumbar arthrodesis |
US6936070B1 (en) * | 2001-01-17 | 2005-08-30 | Nabil L. Muhanna | Intervertebral disc prosthesis and methods of implantation |
US7090698B2 (en) * | 2001-03-02 | 2006-08-15 | Facet Solutions | Method and apparatus for spine joint replacement |
US7025787B2 (en) * | 2001-11-26 | 2006-04-11 | Sdgi Holdings, Inc. | Implantable joint prosthesis and associated instrumentation |
US7485134B2 (en) * | 2001-12-07 | 2009-02-03 | Simonson Rush E | Vertebral implants adapted for posterior insertion |
US7052515B2 (en) * | 2001-12-07 | 2006-05-30 | Simonson Rush E | Vertebral implant with dampening matrix adapted for posterior insertion |
EP1344508B1 (de) * | 2002-03-12 | 2007-06-06 | Cervitech, Inc. | Zwischenwirbelprothese, insbesondere für die Halswirbelsäule |
RU2303422C2 (ru) * | 2002-03-12 | 2007-07-27 | Сервитек Инк. | Межпозвонковый протез и система межпозвонковых протезов, в частности для шейного отдела позвоночника |
US6726720B2 (en) * | 2002-03-27 | 2004-04-27 | Depuy Spine, Inc. | Modular disc prosthesis |
US7717959B2 (en) * | 2002-03-30 | 2010-05-18 | Lytton William | Intervertebral device and method of use |
US6706068B2 (en) * | 2002-04-23 | 2004-03-16 | Bret A. Ferree | Artificial disc replacements with natural kinematics |
US6770095B2 (en) * | 2002-06-18 | 2004-08-03 | Depuy Acroned, Inc. | Intervertebral disc |
ES2269743T3 (es) * | 2002-09-02 | 2007-04-01 | Synthes Gmbh | Implante intervertebral con articulacion de tres piezas. |
US6966929B2 (en) * | 2002-10-29 | 2005-11-22 | St. Francis Medical Technologies, Inc. | Artificial vertebral disk replacement implant with a spacer |
US7083649B2 (en) * | 2002-10-29 | 2006-08-01 | St. Francis Medical Technologies, Inc. | Artificial vertebral disk replacement implant with translating pivot point |
US7204852B2 (en) * | 2002-12-13 | 2007-04-17 | Spine Solutions, Inc. | Intervertebral implant, insertion tool and method of inserting same |
WO2004058098A2 (en) * | 2002-12-17 | 2004-07-15 | Amedica Corporation | Total disc implant |
US7048764B2 (en) * | 2003-01-07 | 2006-05-23 | Ferree Bret A | Artificial disc replacements with articulating components |
US20040158254A1 (en) * | 2003-02-12 | 2004-08-12 | Sdgi Holdings, Inc. | Instrument and method for milling a path into bone |
US6908484B2 (en) * | 2003-03-06 | 2005-06-21 | Spinecore, Inc. | Cervical disc replacement |
US7621956B2 (en) * | 2003-07-31 | 2009-11-24 | Globus Medical, Inc. | Prosthetic spinal disc replacement |
DE10339170B4 (de) * | 2003-08-22 | 2009-10-15 | Aesculap Ag | Zwischenwirbelimplantat |
US20050171610A1 (en) * | 2004-01-09 | 2005-08-04 | Sdgi Holdings, Inc. | Mobile bearing spinal device and method |
US7875077B2 (en) * | 2004-01-09 | 2011-01-25 | Warsaw Orthopedic, Inc. | Support structure device and method |
US7556651B2 (en) * | 2004-01-09 | 2009-07-07 | Warsaw Orthopedic, Inc. | Posterior spinal device and method |
US20050154467A1 (en) * | 2004-01-09 | 2005-07-14 | Sdgi Holdings, Inc. | Interconnected spinal device and method |
US7771479B2 (en) * | 2004-01-09 | 2010-08-10 | Warsaw Orthopedic, Inc. | Dual articulating spinal device and method |
US20060069441A1 (en) * | 2004-09-29 | 2006-03-30 | Zucherman James F | Posterior approach implant method for assembly of multi-piece artificial spinal disk replacement device in situ |
US20060069438A1 (en) * | 2004-09-29 | 2006-03-30 | Zucherman James F | Multi-piece artificial spinal disk replacement device with multi-segmented support plates |
US7811326B2 (en) * | 2006-01-30 | 2010-10-12 | Warsaw Orthopedic Inc. | Posterior joint replacement device |
US20070270862A1 (en) * | 2006-03-30 | 2007-11-22 | Sdgi Holdings, Inc. | Instruments and methods for preparing an intervertebral space |
-
2003
- 2003-01-17 GB GBGB0301085.7A patent/GB0301085D0/en not_active Ceased
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2004
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- 2004-01-15 ES ES04702362T patent/ES2303045T3/es not_active Expired - Lifetime
- 2004-01-15 EP EP04702362A patent/EP1587461B1/de not_active Expired - Lifetime
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- 2004-01-15 DE DE602004012960T patent/DE602004012960T2/de not_active Expired - Lifetime
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ES2303045T3 (es) | 2008-08-01 |
EP1587461A2 (de) | 2005-10-26 |
EP1587461B1 (de) | 2008-04-09 |
US20060259147A1 (en) | 2006-11-16 |
DE602004012960T2 (de) | 2009-06-04 |
WO2004064692A3 (en) | 2004-10-07 |
DE602004012960D1 (de) | 2008-05-21 |
WO2004064692A2 (en) | 2004-08-05 |
GB0301085D0 (en) | 2003-02-19 |
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