ATE389416T1 - Behandlung von knorpelerkrankungen - Google Patents

Behandlung von knorpelerkrankungen

Info

Publication number
ATE389416T1
ATE389416T1 AT01937482T AT01937482T ATE389416T1 AT E389416 T1 ATE389416 T1 AT E389416T1 AT 01937482 T AT01937482 T AT 01937482T AT 01937482 T AT01937482 T AT 01937482T AT E389416 T1 ATE389416 T1 AT E389416T1
Authority
AT
Austria
Prior art keywords
igf
treatment
cartilage
cartilary
diseases
Prior art date
Application number
AT01937482T
Other languages
English (en)
Inventor
Yves Dubaquie
Ellen H Filvaroff
Henry B Lowman
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE389416T1 publication Critical patent/ATE389416T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743—Insulin-like growth factor binding protein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
AT01937482T 2000-05-16 2001-05-16 Behandlung von knorpelerkrankungen ATE389416T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20449000P 2000-05-16 2000-05-16
US24898500P 2000-11-15 2000-11-15

Publications (1)

Publication Number Publication Date
ATE389416T1 true ATE389416T1 (de) 2008-04-15

Family

ID=26899527

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01937482T ATE389416T1 (de) 2000-05-16 2001-05-16 Behandlung von knorpelerkrankungen

Country Status (9)

Country Link
US (4) US20030069177A1 (de)
EP (1) EP1282437B1 (de)
AT (1) ATE389416T1 (de)
AU (1) AU2001263215A1 (de)
DE (1) DE60133271T2 (de)
DK (1) DK1282437T3 (de)
ES (1) ES2301547T3 (de)
HK (1) HK1050321A1 (de)
WO (1) WO2001087323A2 (de)

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US8173162B2 (en) * 2003-02-26 2012-05-08 Zimmer Orthobiologics, Inc. Preparation for repairing cartilage tissue, especially articular cartilage defects
EP1740190A1 (de) * 2004-03-05 2007-01-10 Synthes GmbH Verwendung eines gemisches für die herstellung eines mittels zur behandlung von defektem oder degeneriertem knorpel in vivo und bei der herstellung von natürlichem knorpelersatz in vitro
WO2005122723A2 (en) * 2004-06-09 2005-12-29 Beth Israel Deaconess Medical Center Compositions and methods that enhance articular cartilage repair
EP1764117A1 (de) 2005-09-20 2007-03-21 Zimmer GmbH Implantat zur Wiederherstellung von Knorpeldefekten und Verfahren zu seiner Herstellung
ES2614510T3 (es) 2006-02-07 2017-05-31 Spinalcyte, Llc Método y composiciones para la reparación del cartílago usando un biorreactor in vivo
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EP3146977A1 (de) 2010-03-19 2017-03-29 Baxalta GmbH Tfpi-hemmer und verfahren zur verwendung
US20140314726A1 (en) * 2011-11-09 2014-10-23 Spinalcyte, Llc Fibroblasts for treatment of degenerative disc disease
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EP2864353B1 (de) * 2012-06-25 2019-03-27 The Brigham and Women's Hospital, Inc. Selektive knorpeltherapie
EP3466964A1 (de) 2012-07-06 2019-04-10 3-D Matrix Ltd. Füllabschlussverfahren für peptidlösungen
CA2915249C (en) 2013-06-19 2022-04-12 Spinalcyte, Llc Adipose cells for chondrocyte applications
WO2015136370A2 (en) 2014-03-10 2015-09-17 3-D Matrix, Ltd. Sterilization and filtration of peptide compositions
EP3116524B1 (de) 2014-03-10 2018-11-28 3-D Matrix Ltd. Peptides autoassémblants pour le traitement de la bulle pulmonaire
ES2711728T3 (es) 2014-03-10 2019-05-07 3 D Matrix Ltd Composiciones de péptidos de autoensamblaje
WO2017120092A1 (en) 2016-01-06 2017-07-13 3-D Matrix, Ltd. Combination compositions
EP3723726A1 (de) 2017-12-15 2020-10-21 3-D Matrix, Ltd. Tensidpeptidnanostrukturen und verwendungen in der wirkstoffabgabe

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Also Published As

Publication number Publication date
US20030211992A1 (en) 2003-11-13
US8110548B2 (en) 2012-02-07
WO2001087323A2 (en) 2001-11-22
HK1050321A1 (en) 2003-06-20
AU2001263215A1 (en) 2001-11-26
ES2301547T3 (es) 2008-07-01
DE60133271T2 (de) 2009-04-23
US20100130411A1 (en) 2010-05-27
EP1282437B1 (de) 2008-03-19
WO2001087323A3 (en) 2002-04-11
US7423017B2 (en) 2008-09-09
US20090011988A1 (en) 2009-01-08
US20030069177A1 (en) 2003-04-10
US7947650B2 (en) 2011-05-24
DE60133271D1 (de) 2008-04-30
DK1282437T3 (da) 2008-06-30
EP1282437A2 (de) 2003-02-12

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