ATE376830T1 - Benzo(b(thiophenderivate und verfahren zu deren herstellung - Google Patents

Benzo(b(thiophenderivate und verfahren zu deren herstellung

Info

Publication number
ATE376830T1
ATE376830T1 AT02700711T AT02700711T ATE376830T1 AT E376830 T1 ATE376830 T1 AT E376830T1 AT 02700711 T AT02700711 T AT 02700711T AT 02700711 T AT02700711 T AT 02700711T AT E376830 T1 ATE376830 T1 AT E376830T1
Authority
AT
Austria
Prior art keywords
thiophene
bromomethyl
benzo
production
thiophene derivatives
Prior art date
Application number
AT02700711T
Other languages
English (en)
Inventor
Hirosi Saitoh
Naoki Tsuchiya
Tsuyoshi Mizuno
Tomohide Ida
Yoshiyuki Sawai
Original Assignee
Teijin Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Pharma Ltd filed Critical Teijin Pharma Ltd
Application granted granted Critical
Publication of ATE376830T1 publication Critical patent/ATE376830T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT02700711T 2001-02-22 2002-02-22 Benzo(b(thiophenderivate und verfahren zu deren herstellung ATE376830T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001046275 2001-02-22
JP2001135927 2001-05-07

Publications (1)

Publication Number Publication Date
ATE376830T1 true ATE376830T1 (de) 2007-11-15

Family

ID=26609879

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02700711T ATE376830T1 (de) 2001-02-22 2002-02-22 Benzo(b(thiophenderivate und verfahren zu deren herstellung

Country Status (16)

Country Link
US (1) US6884896B2 (de)
EP (2) EP1362854B1 (de)
JP (1) JP3999128B2 (de)
KR (1) KR100922485B1 (de)
CN (1) CN100457750C (de)
AT (1) ATE376830T1 (de)
AU (1) AU2002233698B2 (de)
CA (1) CA2406913C (de)
DE (1) DE60223227T8 (de)
ES (1) ES2292712T3 (de)
HK (1) HK1057215A1 (de)
NO (1) NO328158B1 (de)
NZ (1) NZ522150A (de)
PL (1) PL358494A1 (de)
PT (1) PT1362854E (de)
WO (1) WO2002066457A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100548990C (zh) * 2001-02-22 2009-10-14 帝人株式会社 苯并咪唑衍生物的制备方法
CL2004001034A1 (es) * 2003-05-14 2005-03-28 Teijin Pharma Ltd Formas cristalinas de acido 4-(1-((,etilbenzotiofen-3-il)me til)benzimidazol-2-iltio)butanoico; procedimiento de preparacion de las formas cristalinas; composicion farmaceutica; y su uso para el tratamiento de enfermedades inflamatorias, alergicas, r
JP4387360B2 (ja) * 2003-08-22 2009-12-16 帝人ファーマ株式会社 キマーゼ阻害剤を有効成分として含有する薬剤
US7169807B2 (en) * 2004-04-09 2007-01-30 Allergan, Inc. 10-Hydroxy-11-dihydroprostaglandin analogs as selective EP4 agonists
DE102004021637A1 (de) * 2004-05-03 2005-12-01 Merck Patent Gmbh Dihydrobenzothiophene
WO2006052026A1 (ja) * 2004-11-12 2006-05-18 Teijin Pharma Limited ベンズイミダゾール誘導体の酸性塩及びその結晶
KR20080058435A (ko) 2005-10-27 2008-06-25 데이진 화-마 가부시키가이샤 벤조[ｂ]티오펜 유도체 및 그 제조 방법
RU2008121223A (ru) 2005-10-27 2009-12-10 Тейдзин Фарма Лимитед (Jp) Производные 3-гидроксиметилбензо[ь]тиофена и способ их получения
UA95788C2 (en) 2005-12-15 2011-09-12 Ф. Хоффманн-Ля Рош Аг Fused pyrrole derivatives
PL2944633T3 (pl) 2012-11-14 2018-08-31 Teijin Pharma Limited Pochodna pirydyny
US11236062B2 (en) * 2016-03-31 2022-02-01 Fujifilm Toyama Chemical Co., Ltd. Method for producing 5-(bromomethyl)-1-benzothiophene

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1174411A (en) 1966-03-02 1969-12-17 Aspro Nicholas Ltd Novel Benzothiophen Compounds, Compositions containing them and processes for their manufacture
US3910955A (en) * 1970-12-21 1975-10-07 Aspro Nicholas Ltd Benzothiophene-ethylamines
US4255196A (en) * 1979-02-23 1981-03-10 Rohm And Haas Company Lithographic ink of reduced volatile solvent content for reducing atmospheric pollution
CN1073563C (zh) * 1994-04-11 2001-10-24 中外制药株式会社 4,6－二叔丁基－2,3－二氢苯并噻吩衍生物
TR200100047T2 (tr) 1998-07-15 2001-10-22 Teijin Limited Tiyobenzimidazol türevleri
PT1078923E (pt) * 1999-08-02 2006-07-31 Hoffmann La Roche Processo para a preparacao de derivados de benzotiofeno
PT1249450E (pt) * 2000-01-17 2008-01-02 Teijin Pharma Ltd Derivados de benzimidazole como inibidores de quimase humana
JP2001199968A (ja) 2000-01-18 2001-07-24 Teijin Ltd アミノベンズイミダゾール誘導体
GB0001439D0 (en) * 2000-01-21 2000-03-08 R P Adam Limited Method of controlling microbiological activity in water storage tanks and apparatus for use in such method
CN1205204C (zh) * 2001-05-07 2005-06-08 帝人株式会社 3－羟甲基－苯并[b]噻吩衍生物及其制备方法

Also Published As

Publication number Publication date
EP1362854B1 (de) 2007-10-31
NO20025053D0 (no) 2002-10-21
KR100922485B1 (ko) 2009-10-20
DE60223227T8 (de) 2008-11-27
DE60223227D1 (de) 2007-12-13
CN100457750C (zh) 2009-02-04
EP1792614A1 (de) 2007-06-06
AU2002233698B2 (en) 2007-11-08
WO2002066457A1 (fr) 2002-08-29
CA2406913A1 (en) 2002-08-29
CN1461301A (zh) 2003-12-10
EP1362854A4 (de) 2004-06-09
NO328158B1 (no) 2009-12-21
NZ522150A (en) 2006-03-31
JP3999128B2 (ja) 2007-10-31
US20030176490A1 (en) 2003-09-18
PT1362854E (pt) 2008-01-21
DE60223227T2 (de) 2008-08-14
CA2406913C (en) 2011-04-19
HK1057215A1 (en) 2004-03-19
PL358494A1 (en) 2004-08-09
NO20025053L (no) 2002-11-29
EP1362854A1 (de) 2003-11-19
US6884896B2 (en) 2005-04-26
JPWO2002066457A1 (ja) 2004-06-17
ES2292712T3 (es) 2008-03-16
KR20030005293A (ko) 2003-01-17

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