ATE362755T1 - Stabile n-propargyl-1-aminoindan enthaltende zusammensetzungen - Google Patents

Stabile n-propargyl-1-aminoindan enthaltende zusammensetzungen

Info

Publication number: ATE362755T1
Authority: AT; Austria
Prior art keywords: pct; propargyl; aminoindane; compositions containing; stable compositions
Prior art date: 1995-09-20

Application number

AT96930344T

Other languages

English (en)

Inventor

Peskin Tirtsah Berger

Fanny Caciularu

Original Assignee

Teva Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-20

Filing date

1996-09-18

Publication date

2007-06-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11068003&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE362755(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-09-18 Application filed by Teva Pharma filed Critical Teva Pharma

2007-06-15 Application granted granted Critical

2007-06-15 Publication of ATE362755T1 publication Critical patent/ATE362755T1/de

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Organic Chemistry (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Solid Fuels And Fuel-Associated Substances (AREA)

AT96930344T 1995-09-20 1996-09-18 Stabile n-propargyl-1-aminoindan enthaltende zusammensetzungen ATE362755T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IL11535795A IL115357A (en)	1995-09-20	1995-09-20	Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols

Publications (1)

Publication Number	Publication Date
ATE362755T1 true ATE362755T1 (de)	2007-06-15

Family

ID=11068003

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96930344T ATE362755T1 (de)	1995-09-20	1996-09-18	Stabile n-propargyl-1-aminoindan enthaltende zusammensetzungen

Country Status (13)

Country	Link
US (1)	US6126968A (de)
EP (1)	EP0858328B1 (de)
JP (1)	JP4108750B2 (de)
AT (1)	ATE362755T1 (de)
AU (1)	AU728524B2 (de)
CA (1)	CA2232310C (de)
DE (1)	DE69637096T2 (de)
DK (1)	DK0858328T3 (de)
ES (1)	ES2287940T3 (de)
HU (1)	HU225859B1 (de)
IL (1)	IL115357A (de)
PT (1)	PT858328E (de)
WO (1)	WO1997012583A2 (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5744500A (en)	1990-01-03	1998-04-28	Teva Pharmaceutical Industries, Ltd.	Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof
IL118836A (en) *	1996-07-11	2001-01-11	Teva Pharma	Pharmaceutical compositions comprising s-(-)-n-propargyl-1-aminoindan
EP1242066B1 (de)	1999-10-27	2006-06-28	Teva Pharmaceutical Industries Ltd.	Verwendung von 1-aminoindanderivaten zur behandlung der manie in verbindung mit manisch-depressiver erkrankung
ES2588780T3 (es) *	2002-11-15	2016-11-04	Teva Pharmaceutical Industries Limited	Uso de rasagilina con o sin riluzol para el tratamiento de la esclerosis lateral amiotrófica
GB2411355B (en)	2004-02-27	2006-02-22	Niche Generics Ltd	Pharmaceutical composition
JP2008507586A (ja) *	2004-07-26	2008-03-13	テバファーマシューティカルインダストリーズリミティド	ラサグリンを含む、医薬投与剤
DK1729735T3 (da) *	2004-11-10	2007-10-08	Teva Pharma	Fremgangsmåde til fremstilling af sammenpressede, faste doseringsformer, som er velegnede til brug sammen med lægemidler med lav vandoplöselighed og sammenpressede, faste doseringsformer fremstillet derved
US8367105B2 (en)	2004-11-10	2013-02-05	Teva Pharmaceutical Industries, Ltd.	Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby
WO2006057912A2 (en) *	2004-11-24	2006-06-01	Teva Pharmaceutical Industries, Ltd.	Rasagiline orally disintegrating compositions
RS52867B (en) *	2005-02-17	2013-12-31	Teva Pharmaceutical Industries Ltd.	GLATIRAMER ACETATOM AND RAZAGILIN COMBINED THERAPY FOR MULTIPLE SCLEROSIS
US20100167983A1 (en) *	2007-10-22	2010-07-01	Teva Pharmaceutical Industries, Ltd.	Combination therapy with glatiramer acetate and rasagiline for the treatment of multiple sclerosis
CA2600011C (en)	2005-02-23	2015-11-10	Teva Pharmaceutical Industries Ltd.	Rasagiline formulations of improved content uniformity
WO2007061717A2 (en) *	2005-11-17	2007-05-31	Teva Pharmaceutical Industries, Ltd.	Methods for isolating propargylated aminoindans
US7572834B1 (en)	2005-12-06	2009-08-11	Teva Pharmaceutical Industries, Ltd.	Rasagiline formulations and processes for their preparation
BRPI0620659A2 (pt)	2005-12-09	2017-10-31	Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd	método para a prevenção do aparecimento de sintomas de uma doença neurodegenerativa em um indivíduo predisposto à doença neurodegenerativa, método de redução de stress oxidante no cérebro de um indivíduo afligido com stress oxidante, método de tratamento de um indivíduo afligido com a degeneração cognitiva suave e composição farmacêutica
US8809310B2 (en)	2006-02-21	2014-08-19	Teva Pharmaceutical Industries, Ltd.	Use of rasagiline for the treatment of multiple system atrophy
TW200744576A (en)	2006-02-24	2007-12-16	Teva Pharma	Propargylated aminoindans, processes for preparation, and uses thereof
JP5769923B2 (ja)	2006-04-03	2015-08-26	テバファーマシューティカルインダストリーズリミティド	レストレスレッグス症候群の治療のためのラサギリンの使用
DE202006020710U1 (de)	2006-05-09	2009-12-31	Teva Pharmaceutical Industries Ltd.	Zusammensetzungen mit Rosiglitazonmaleat
EP1892233A1 (de) *	2006-08-18	2008-02-27	Ratiopharm GmbH	Neue Salze des Wirkstoffs Rasagilin
RS52784B (en)	2006-12-14	2013-10-31	Teva Pharmaceutical Industries Ltd.	They're TANATE RAZAGILINA
EP2101569B1 (de) *	2006-12-14	2011-10-19	Teva Pharmaceutical Industries, Ltd.	Kristalline feste rasagilin-base
EP1987816A1 (de) *	2007-04-30	2008-11-05	Ratiopharm GmbH	Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff
EP2194780A4 (de) *	2007-09-05	2010-10-27	Teva Pharma	Verfahren zur behandlung von glaukom mittels rasagilin
US8188149B2 (en) *	2007-09-17	2012-05-29	Teva Pharmaceutical Industries, Ltd.	Use of R(+)-N-propargy1-1-aminoindan to treat or prevent hearing loss
EP2234478A4 (de) *	2008-01-11	2013-01-23	Teva Pharma	Rasagilinformulierungen, ihre herstellung und verwendung
US20090247537A1 (en) *	2008-03-25	2009-10-01	William Dale Overfield	Methods for preventing or treating bruxism using dopaminergic agents
US20110117200A1 (en) *	2008-03-31	2011-05-19	Actavis Group Ptc Ehf	Rasagiline mesylate particles and process for the preparation thereof
MX2010013766A (es) *	2008-06-13	2011-03-15	Teva Pharmaceutical Ind Ltd Star	Rasagilina para modificacion de enfermedad de parkinson.
CN102065853A (zh) *	2008-06-19	2011-05-18	泰华制药工业有限公司	制备和干燥固体雷沙吉兰碱的方法
EP2299993A4 (de) *	2008-06-19	2014-08-20	Teva Pharma	Verfahren zum reinigen einer rasagilin-base
US20100189790A1 (en) *	2009-01-23	2010-07-29	Teva Pharmaceutical Industries, Ltd.	Delayed release rasagiline formulation
EP2218444A3 (de)	2009-01-23	2010-08-25	Teva Pharmaceutical Industries, Ltd.	Rasagilinformulierung mit verzögerter Freisetzung
KR20110130410A (ko)	2009-03-05	2011-12-05	산도즈 아게	라사길린 메실레이트를 함유하는 제약 조성물
PT2451771E (pt)	2009-07-09	2014-09-19	Ratiopharm Gmbh	Sais de rasagilina e suas preparações farmacêuticas
CN102048717B (zh) *	2009-10-29	2014-02-19	重庆医药工业研究院有限责任公司	一种稳定的雷沙吉兰组合物
EP2515891A4 (de)	2009-12-22	2013-06-05	Teva Pharma	3-keto-n-propargyl-1-aminoindan
EP2563347B1 (de)	2010-04-30	2016-10-12	Teikoku Pharma USA, Inc.	Transdermale propynylaminoindanzusammensetzungen
EP2389927A1 (de)	2010-05-30	2011-11-30	Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi	Pharmazeutische Formulationen von Rasagilin
CA2806737A1 (en)	2010-07-27	2012-02-02	Teva Pharmaceutical Industries Ltd.	Dispersions of rasagiline citrate
WO2012015950A1 (en)	2010-07-27	2012-02-02	Teva Pharmaceutical Industries Ltd.	Use of rasagiline for the treatment of olfactory dysfunction
JP5906302B2 (ja)	2011-03-24	2016-04-20	テイコクファーマユーエスエーインコーポレーテッド	作用剤層および作用剤変換層を含む経皮組成物
KR20140090996A (ko) *	2011-10-10	2014-07-18	테바 파마슈티컬 인더스트리즈 리미티드	R(+)-n-폼일-프로파길-아미노인단
AU2012323351A1 (en)	2011-10-10	2014-05-22	Teva Pharmaceutical Industries Ltd.	R(+)-N-methyl-propargyl-aminoindan
EA201490756A1 (ru) *	2011-10-10	2014-09-30	Тева Фармасьютикал Индастриз, Лтд.	Разагилина цитрамид
US9913812B2 (en)	2011-11-09	2018-03-13	Teikoku Pharma Usa, Inc.	Methods for the treatment of skin neoplasms
DE102012000786A1 (de)	2012-01-18	2013-07-18	Stada Arzneimittel Ag	Verfahren zur Herstellung einer festen pharmazeutischen Zusammensetzung, enthaltend den Wirkstoff Rasagilin
WO2013139387A1 (en)	2012-03-21	2013-09-26	Synthon Bv	Stabilized pharmaceutical compositions comprising rasagiline salts
WO2013175493A1 (en)	2012-04-09	2013-11-28	Cadila Healthcare Limited	Stable oral pharmaceutical compositions
MX2015002062A (es)	2012-08-17	2015-06-05	Teva Pharma	Formulaciones parenterales de rasagilina.
US9205061B2 (en)	2012-11-02	2015-12-08	Teikoku Pharma Usa, Inc.	Propynylaminoindan transdermal compositions
EP2764862A1 (de) *	2013-02-06	2014-08-13	Galenicum Health S.L.	Tabletten mit unmittelbarer Freisetzung von Rasagilin Hemitartrate
EP2796130A3 (de) *	2013-02-06	2015-02-25	Galenicum Health S.L.	Tabletten mit unmittelbarer Freisetzung von Rasagilin Hemitartrate
CN115400090A (zh) *	2022-10-09	2022-11-29	北京新领先医药科技发展有限公司	一种雷沙吉兰的口崩片组合物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1187017A (en) *	1966-07-16	1970-04-08	Aspro Nicholas Ltd	Substituted 1-Amino Indanes and Tetrahydronaphthalens
GB8909793D0 (en) *	1989-04-28	1989-06-14	Beecham Group Plc	Pharmaceutical formulation
IL92952A (en) *	1990-01-03	1994-06-24	Teva Pharma	R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them
CA2039742A1 (en) *	1990-04-23	1991-10-24	Andrew B. Dennis	Tablet composition and method for problem pharmaceutical materials
IL99759A (en) *	1991-10-16	1997-06-10	Teva Pharma	Mono-fluorinated derivatives of n-propargyl-1-aminoindan, their preparation and pharmaceutical compositions containing them
IL111240A (en) *	1993-10-18	2001-10-31	Teva Pharma	Salts of r(+) - enantiomers of n- propargyl-1-aminoindan and pharmaceutical compositions comprising them
IL112779A (en) *	1994-03-01	1999-11-30	Gergely Gerhard	Granular product or tablet containing an efferescent system and an active pharmaceutical substance and its preparation
SK284383B6 (sk) *	1995-03-02	2005-02-04	R.P. Scherer Limited	Farmaceutický prostriedok na orálne podávanie obsahujúci inhibítory monoaminoxidázy B a jeho použitie

1995
- 1995-09-20 IL IL11535795A patent/IL115357A/xx not_active IP Right Cessation
1996
- 1996-09-18 ES ES96930344T patent/ES2287940T3/es not_active Expired - Lifetime
- 1996-09-18 EP EP96930344A patent/EP0858328B1/de not_active Expired - Lifetime
- 1996-09-18 DK DK96930344T patent/DK0858328T3/da active
- 1996-09-18 CA CA002232310A patent/CA2232310C/en not_active Expired - Lifetime
- 1996-09-18 AU AU69427/96A patent/AU728524B2/en not_active Expired
- 1996-09-18 WO PCT/IL1996/000115 patent/WO1997012583A2/en active IP Right Grant
- 1996-09-18 AT AT96930344T patent/ATE362755T1/de active
- 1996-09-18 HU HU9802999A patent/HU225859B1/hu unknown
- 1996-09-18 DE DE69637096T patent/DE69637096T2/de not_active Expired - Lifetime
- 1996-09-18 US US09/043,475 patent/US6126968A/en not_active Expired - Lifetime
- 1996-09-18 JP JP51411997A patent/JP4108750B2/ja not_active Expired - Lifetime
- 1996-09-18 PT PT96930344T patent/PT858328E/pt unknown

Also Published As

Publication number	Publication date
IL115357A0 (en)	1995-12-31
IL115357A (en)	2000-01-31
AU728524B2 (en)	2001-01-11
HUP9802999A3 (en)	1999-05-28
EP0858328A4 (de)	2001-07-11
JPH11512736A (ja)	1999-11-02
HU225859B1 (en)	2007-11-28
CA2232310A1 (en)	1997-04-10
PT858328E (pt)	2007-08-20
JP4108750B2 (ja)	2008-06-25
DK0858328T3 (da)	2007-09-03
EP0858328B1 (de)	2007-05-23
AU6942796A (en)	1997-04-28
WO1997012583A2 (en)	1997-04-10
ES2287940T3 (es)	2007-12-16
HUP9802999A2 (hu)	1999-04-28
DE69637096D1 (de)	2007-07-05
WO1997012583A3 (en)	1997-06-05
CA2232310C (en)	2008-01-08
EP0858328A2 (de)	1998-08-19
US6126968A (en)	2000-10-03
DE69637096T2 (de)	2008-01-31

Legal Events

Date

Code

Title

Description

2007-11-15

UEP

Publication of translation of european patent specification

Ref document number: 0858328

Country of ref document: EP

Publication	Publication Date	Title
ATE362755T1 (de)	2007-06-15	Stabile n-propargyl-1-aminoindan enthaltende zusammensetzungen
UA26455C2 (uk)	1999-08-30	Лікарський препарат у формі таблеток із сповільhеhим вивільhеhhям активhого іhгредієhта
TR27835A (tr)	1995-08-31	Sübstitüe edilmis azadiokzasikloalkenler.
ZA948670B (en)	1995-07-04	New benzoyl guanidine derivatives,the preparation thereof and their use in pharmaceutical compositions
YU13695A (sh)	1999-07-28	Upotreba 2-fenil-3-aroilbenzotiofena i njihove farmaceutske formulacije
AU4264396A (en)	1996-06-19	Cosmetic or pharmaceutical compositions containing mangiferin or derivatives thereof
CA2214026A1 (en)	1996-09-06	Pharmaceutical compositions comprising monoamine oxidase b inhibitors
FI972434A0 (fi)	1997-06-06	Lamotrigiiniä sisältävä farmaseuttinen koostumus
IT1272149B (it)	1997-06-11	Composizione farmeceutiche ad attivita' analgesica
DE69433012D1 (de)	2003-09-11	Verfahren zur herstellung von oralen dosierungsformulierungen enthaltend diclofenac
CA2152998A1 (en)	1996-01-02	Anti-hyperglycemia pharmaceutical composition
AU2774292A (en)	1993-05-21	Toiletries composition
AU7470098A (en)	1998-11-24	Antithrombotic agents
ATE160938T1 (de)	1997-12-15	Feste orale pharmazeutische zubereitung mit gemfibrozil als aktiver inhaltsstoff und verfahren zur herstellung
MX9304403A (es)	1994-04-29	Derivados farmacologicamente activos de ó-(aminometilo terciario)-bencenmetanol
GB9513750D0 (en)	1995-09-06	Use of allylamines
KR950700743A (ko)	1995-02-20	프로스타사이클린류를 활성성분으로서 함유하는 외용 피부치료제 조성물(dermatologic preparation composition containing prostacyclin as active ingredient)
SI0805817T1 (de)	2001-12-31
AU7274198A (en)	1998-11-24	Antithrombotic agents
TW333453B (en)	1998-06-11	Pharmaceutical composition comprising toremifene for use in the treatment of autoimmune diseases
MX9605633A (es)	1998-05-31	Composicion farmaceutica, metodo y dispositivo para prevenir o tratar resequedad de los ojos o enfermedad ocasionada por la misma.