ATE360063T1 - Nicht störendes, dreidimensionales system für die kultivierung und ernte verankerungsabhängiger zellen - Google Patents
Nicht störendes, dreidimensionales system für die kultivierung und ernte verankerungsabhängiger zellenInfo
- Publication number
- ATE360063T1 ATE360063T1 AT01981506T AT01981506T ATE360063T1 AT E360063 T1 ATE360063 T1 AT E360063T1 AT 01981506 T AT01981506 T AT 01981506T AT 01981506 T AT01981506 T AT 01981506T AT E360063 T1 ATE360063 T1 AT E360063T1
- Authority
- AT
- Austria
- Prior art keywords
- interruptional
- anchorage
- harvesting
- cultivation
- dimensional system
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0062—General methods for three-dimensional culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0012—Cell encapsulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/067—Hepatocytes
- C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
- A61K2035/128—Immunoprotecting barriers, e.g. jackets, diffusion chambers capsules, e.g. microcapsules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/72—Chitin, chitosan
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23925900P | 2000-10-12 | 2000-10-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE360063T1 true ATE360063T1 (de) | 2007-05-15 |
Family
ID=22901354
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01981506T ATE360063T1 (de) | 2000-10-12 | 2001-10-12 | Nicht störendes, dreidimensionales system für die kultivierung und ernte verankerungsabhängiger zellen |
Country Status (6)
Country | Link |
---|---|
US (4) | US6905875B2 (de) |
EP (1) | EP1326968B1 (de) |
AT (1) | ATE360063T1 (de) |
AU (1) | AU2002213143A1 (de) |
DE (1) | DE60127983T2 (de) |
WO (1) | WO2002031135A1 (de) |
Families Citing this family (74)
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SG102044A1 (en) * | 2002-04-22 | 2004-02-27 | Cordlife Pte Ltd | Cell culture system |
EP1374893A1 (de) | 2002-06-17 | 2004-01-02 | NovImmune S.A. | Impfung mit Immuno-isolierten Zellen die einen Immunomodulator Produzieren |
WO2004069169A2 (en) | 2003-01-31 | 2004-08-19 | Scimed Life Systems, Inc. | Localized drug delivery using drug-loaded nanocapsules and implantable device coated with the same |
US7364585B2 (en) * | 2003-08-11 | 2008-04-29 | Boston Scientific Scimed, Inc. | Medical devices comprising drug-loaded capsules for localized drug delivery |
US8257963B2 (en) * | 2007-06-01 | 2012-09-04 | Depuy Mitek, Inc. | Chondrocyte container and method of use |
US7927599B2 (en) | 2003-09-08 | 2011-04-19 | Ethicon, Inc. | Chondrocyte therapeutic delivery system |
US7897384B2 (en) * | 2003-09-08 | 2011-03-01 | Ethicon, Inc. | Chondrocyte therapeutic delivery system |
US20050272153A1 (en) | 2004-01-27 | 2005-12-08 | Zou Xuenong | Bone tissue engineering by ex vivo stem cells ongrowth into three-dimensional trabecular metal |
US20060134779A1 (en) * | 2004-03-10 | 2006-06-22 | Banes Albert J | Modulation of cell intrinsic strain to control cell modulus, matrix synthesis, secretion, organization, material properties and remodeling of tissue engineered constructs |
US7704714B2 (en) * | 2004-07-26 | 2010-04-27 | Agency For Science, Technology & Research | Encapsulation of cells in biologic compatible scaffolds by coacervation of charged polymers |
US7700333B2 (en) * | 2004-07-26 | 2010-04-20 | Agency For Science Technology & Research | Immobilization of cells in a matrix formed by biocompatible charged polymers under laminar flow conditions |
EP1815244A4 (de) * | 2004-11-11 | 2009-07-22 | Agency Science Tech & Res | Zellkulturvorrichtung |
US7851189B2 (en) | 2005-03-07 | 2010-12-14 | Boston Scientific Scimed, Inc. | Microencapsulated compositions for endoluminal tissue engineering |
US8455088B2 (en) | 2005-12-23 | 2013-06-04 | Boston Scientific Scimed, Inc. | Spun nanofiber, medical devices, and methods |
US7674864B2 (en) * | 2005-12-23 | 2010-03-09 | Boston Scientific Scimed, Inc. | Polymeric hybrid precursors, polymeric hybrid precursor composite matrices, medical devices, and methods |
AU2007212085B2 (en) * | 2006-02-07 | 2011-11-17 | Spinalcyte, Llc | Methods and compositions for repair of cartilage using an in vivo bioreactor |
SG170761A1 (en) * | 2006-03-23 | 2011-05-30 | Pluristem Ltd | Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy |
US20070237749A1 (en) * | 2006-04-07 | 2007-10-11 | Wang Taylor G | Multi-membrane immunoisolation system for cellular transplant |
US20070238169A1 (en) * | 2006-04-11 | 2007-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Cell sorter and culture system |
US20090263849A1 (en) * | 2006-04-21 | 2009-10-22 | Drexel University | Bioprinting Three-Dimensional Structure Onto Microscale Tissue Analog Devices for Pharmacokinetic Study and Other Uses |
US20100047355A1 (en) * | 2006-04-24 | 2010-02-25 | The Johns Hopkins University | Magnetic resonance-detectable, ultrasound-detectable and/or radiopaque microcapsules and uses thereof |
EP2021035B1 (de) * | 2006-05-19 | 2020-08-05 | Versitech Limited | Zellmatrix-mikrokugeln, herstellungsverfahren und anwendungen |
US8168215B2 (en) * | 2006-06-16 | 2012-05-01 | Fmc Biopolymer As | Alginate coated, collagen matrix cellular device, preparative methods, and uses thereof |
US8206816B2 (en) | 2006-08-29 | 2012-06-26 | Florida State University Research Foundation, Inc. | Polymer mechanical damping composites and methods of production |
JP5096486B2 (ja) * | 2006-12-13 | 2012-12-12 | ビーエーエスエフ ソシエタス・ヨーロピア | マイクロカプセル |
US20100143439A1 (en) * | 2007-04-16 | 2010-06-10 | University Of Toledo | Hybrid Biomimetic Particles, Methods of Making Same and Uses Therefor |
US20080281419A1 (en) * | 2007-05-10 | 2008-11-13 | Matheny Robert G | Breast implants and compositions of extracellular matrix |
EP2173858A4 (de) * | 2007-07-02 | 2010-09-08 | Univ Columbia | Verarbeitung von biologisch abgeleitetem verbundgewebe |
EP2185730A4 (de) | 2007-08-23 | 2010-10-27 | Intrexon Corp | Verfahren und zusammensetzungen zur krankheitsdiagnose |
WO2009043052A1 (en) * | 2007-09-27 | 2009-04-02 | Columbia University | Methods and systems for forming biocompatible materials |
NZ584848A (en) | 2007-09-28 | 2012-09-28 | Intrexon Corp | Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof |
EP2203548A4 (de) * | 2007-10-11 | 2014-01-15 | Agency Science Tech & Res | Bildung einer zellstruktur mit transientem linker in einem käfig |
US20090137925A1 (en) * | 2007-11-23 | 2009-05-28 | Divya Cantor | Impedance Spectroscopy Cervix Scanning Apparatus and Method |
WO2009086535A2 (en) * | 2007-12-27 | 2009-07-09 | The Trustees Of Columbia University In The City Of New York | Systems and methods for forming patterned extracellular matrix materials |
US8114918B2 (en) * | 2008-08-15 | 2012-02-14 | The Florida State University Research Foundation, Inc. | Compacted polyelectrolyte complexes and articles |
US20100166822A1 (en) * | 2008-12-31 | 2010-07-01 | Howmedica Osteonics Corp. | Adhesive cartilage implant |
US20110136162A1 (en) * | 2009-08-31 | 2011-06-09 | Drexel University | Compositions and Methods for Functionalized Patterning of Tissue Engineering Substrates Including Bioprinting Cell-Laden Constructs for Multicompartment Tissue Chambers |
US9725689B2 (en) | 2010-10-08 | 2017-08-08 | Terumo Bct, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
KR101835917B1 (ko) | 2011-03-22 | 2018-03-07 | 플루리스템 리미티드 | 방사선 또는 화학적 손상을 치료하는 방법들 |
US10016461B2 (en) | 2012-12-03 | 2018-07-10 | The Regents Of The University Of California | Apparatus and process for growing a heart valve in three-dimensions |
US9968446B2 (en) | 2011-03-23 | 2018-05-15 | The Regents Of The University Of California | Tubular scaffold for fabrication of heart valves |
US10085946B2 (en) * | 2012-09-04 | 2018-10-02 | Technion Research & Development Foundation Limited | Use of decellularized extracellular matrix for encapsulating cells |
TWI512103B (zh) | 2012-11-12 | 2015-12-11 | Ind Tech Res Inst | 細胞培養系統、以及無血清細胞培養方法 |
WO2014169031A1 (en) * | 2013-04-10 | 2014-10-16 | Tufts University | Two and three dimensional decellularized ecm constructs and uses therefor |
DE202014011287U1 (de) | 2013-06-11 | 2019-02-06 | The President And Fellows Of Harvard College | SC-ß Zellen und Zusammensetzungen zur Erzeugung der Zellen |
JP2016523083A (ja) | 2013-06-19 | 2016-08-08 | スパイナルサイト, エルエルシー | 軟骨細胞適用のための脂肪細胞 |
JP6633522B2 (ja) | 2013-11-16 | 2020-01-22 | テルモ ビーシーティー、インコーポレーテッド | バイオリアクターにおける細胞増殖 |
US10253203B2 (en) | 2014-02-04 | 2019-04-09 | The Florida State University Research Foundation, Inc. | Rough polyelectrolyte complex coatings and methods of forming |
JP6783143B2 (ja) | 2014-03-25 | 2020-11-11 | テルモ ビーシーティー、インコーポレーテッド | 培地の受動的補充 |
US20170287540A1 (en) * | 2014-09-25 | 2017-10-05 | Hewlett Packard Enterprise Development Lp | Crosspoint array decoder |
CN106715676A (zh) | 2014-09-26 | 2017-05-24 | 泰尔茂比司特公司 | 按计划供养 |
US9919280B2 (en) | 2014-11-24 | 2018-03-20 | The Florida State University Research Foundation, Inc. | Method of forming polyelectrolyte complex capsules |
EP3234110B1 (de) | 2014-12-18 | 2024-02-28 | President and Fellows of Harvard College | Verfahren zur generierung von stammzell-abgeleiteten beta-zellen und verwendungen davon |
US20160175363A1 (en) * | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | Methods for generating stem cell-derived beta cells and uses thereof |
WO2016100898A1 (en) | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | Serum-free in vitro directed differentiation protocol for generating stem cell-derived b cells and uses thereof |
CN107614678B (zh) | 2014-12-18 | 2021-04-30 | 哈佛学院校长同事会 | 干细胞来源的β细胞的产生方法及其使用方法 |
US10647953B2 (en) | 2015-02-11 | 2020-05-12 | The Florida State University Research Foundation, Inc. | Surface treatment for cell culture |
WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
RU2727697C2 (ru) | 2015-09-25 | 2020-07-23 | Максивакс Са | Вакцинация с использованием иммуно-изолированных клеток, продуцирующих иммуномодулятор |
WO2017152035A1 (en) * | 2016-03-03 | 2017-09-08 | Henry Ford Health System | 3-d collagen scaffold-generated exosomes and uses thereof |
US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
TR201611332A2 (tr) | 2016-08-11 | 2018-02-21 | Mehmet Dogan Asik | Bi̇r mi̇krokapsül ve üreti̇m yöntemi̇ |
US10328535B2 (en) * | 2016-11-07 | 2019-06-25 | International Business Machines Corporation | Self-heating solder flux material |
US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
EP3656841A1 (de) | 2017-03-31 | 2020-05-27 | Terumo BCT, Inc. | Zellexpansion |
WO2019036435A1 (en) * | 2017-08-15 | 2019-02-21 | University Of Maryland College Park | CAPSULES WITH MULTIPLE COMPARTMENTS AND METHODS AND SYSTEMS FOR THEIR FORMATION |
AU2018370029A1 (en) | 2017-11-15 | 2020-07-02 | Vertex Pharmaceuticals Incorporated | Islet cell manufacturing compositions and methods of use |
US20200370033A1 (en) * | 2018-01-03 | 2020-11-26 | Regents Of The University Of Minnesota | Biological assembly including biological component and shield |
CN108251410A (zh) * | 2018-01-24 | 2018-07-06 | 南京大学 | 一种包埋气凝胶的固定化微生物制备方法 |
WO2020033879A1 (en) | 2018-08-10 | 2020-02-13 | Semma Therapeutics, Inc. | Stem cell derived islet differentiation |
US11518971B2 (en) | 2018-11-27 | 2022-12-06 | Research Triangle Institute | Method and apparatus for spatial control of cellular growth |
CN111621493B (zh) * | 2020-06-10 | 2022-02-15 | 航天中心医院 | 可裂解细胞微囊及其制备方法和细胞培养方法 |
CN114177279B (zh) * | 2021-12-23 | 2024-03-26 | 广西信业生物技术有限公司 | 一种纳米微囊结构的医用眼贴及制备方法 |
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US3959078A (en) | 1973-05-18 | 1976-05-25 | Midwest Research Institute | Enzyme immobilization with a thermochemical-photochemical bifunctional agent |
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US4743545A (en) * | 1984-08-09 | 1988-05-10 | Torobin Leonard B | Hollow porous microspheres containing biocatalyst |
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SE464816B (sv) | 1985-10-15 | 1991-06-17 | Nilsson Kjell | Makroporoesa partiklar, foerfarande foer dess framstaellning och dess anvaendning |
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-
2001
- 2001-10-12 US US10/398,957 patent/US6905875B2/en not_active Expired - Fee Related
- 2001-10-12 AT AT01981506T patent/ATE360063T1/de not_active IP Right Cessation
- 2001-10-12 US US09/975,273 patent/US6916640B2/en not_active Expired - Fee Related
- 2001-10-12 DE DE60127983T patent/DE60127983T2/de not_active Expired - Lifetime
- 2001-10-12 EP EP01981506A patent/EP1326968B1/de not_active Expired - Lifetime
- 2001-10-12 WO PCT/US2001/031890 patent/WO2002031135A1/en active IP Right Grant
- 2001-10-12 AU AU2002213143A patent/AU2002213143A1/en not_active Abandoned
-
2005
- 2005-05-26 US US11/137,483 patent/US20050220891A1/en not_active Abandoned
-
2009
- 2009-07-23 US US12/507,900 patent/US7943353B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2002031135A1 (en) | 2002-04-18 |
US20040023370A1 (en) | 2004-02-05 |
AU2002213143A1 (en) | 2002-04-22 |
US7943353B2 (en) | 2011-05-17 |
DE60127983T2 (de) | 2008-01-17 |
EP1326968A1 (de) | 2003-07-16 |
EP1326968B1 (de) | 2007-04-18 |
US20090286278A1 (en) | 2009-11-19 |
US6905875B2 (en) | 2005-06-14 |
US6916640B2 (en) | 2005-07-12 |
EP1326968A4 (de) | 2004-10-06 |
US20050220891A1 (en) | 2005-10-06 |
DE60127983D1 (de) | 2007-05-31 |
US20020094569A1 (en) | 2002-07-18 |
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