ATE350471T1 - Verfahren zur kombinierten parallelen zuführung von agentien und elektroporation für zellstrukturen und verwendung davon - Google Patents
Verfahren zur kombinierten parallelen zuführung von agentien und elektroporation für zellstrukturen und verwendung davonInfo
- Publication number
- ATE350471T1 ATE350471T1 AT02791153T AT02791153T ATE350471T1 AT E350471 T1 ATE350471 T1 AT E350471T1 AT 02791153 T AT02791153 T AT 02791153T AT 02791153 T AT02791153 T AT 02791153T AT E350471 T1 ATE350471 T1 AT E350471T1
- Authority
- AT
- Austria
- Prior art keywords
- cell structure
- agents
- tubes
- electroporation
- parallel delivery
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
- G01N2035/1039—Micropipettes, e.g. microcapillary tubes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1074—Multiple transfer devices arranged in a two-dimensional array
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Radiology & Medical Imaging (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0103957 | 2001-11-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE350471T1 true ATE350471T1 (de) | 2007-01-15 |
Family
ID=20286108
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02791153T ATE350471T1 (de) | 2001-11-27 | 2002-11-27 | Verfahren zur kombinierten parallelen zuführung von agentien und elektroporation für zellstrukturen und verwendung davon |
Country Status (8)
Country | Link |
---|---|
US (4) | US20050026283A1 (de) |
EP (2) | EP1448770A1 (de) |
JP (2) | JP2005510237A (de) |
AT (1) | ATE350471T1 (de) |
AU (2) | AU2002365542A1 (de) |
CA (2) | CA2468424A1 (de) |
DE (1) | DE60217393T2 (de) |
WO (2) | WO2003046170A1 (de) |
Families Citing this family (38)
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US7456012B2 (en) | 1997-11-06 | 2008-11-25 | Cellectricon Ab | Method and apparatus for spatially confined electroporation |
EP1448770A1 (de) | 2001-11-27 | 2004-08-25 | Cellectricon AB | Verfahren zur kombinierten sequentiellen zuführung von agentien und elektroporation für zellstrukturen und verwendung davon |
JP4511189B2 (ja) * | 2002-02-12 | 2010-07-28 | セレクトリコン アーベー | センサーの周囲の溶液環境を迅速に変化させるシステム及び方法 |
US8232074B2 (en) | 2002-10-16 | 2012-07-31 | Cellectricon Ab | Nanoelectrodes and nanotips for recording transmembrane currents in a plurality of cells |
US8058056B2 (en) | 2004-03-12 | 2011-11-15 | The Regents Of The University Of California | Method and apparatus for integrated cell handling and measurements |
US8293524B2 (en) | 2006-03-31 | 2012-10-23 | Fluxion Biosciences Inc. | Methods and apparatus for the manipulation of particle suspensions and testing thereof |
US20090053813A1 (en) * | 2007-08-24 | 2009-02-26 | David Mark Evans | Multiplexed electroporation apparatus |
WO2009067142A1 (en) * | 2007-11-21 | 2009-05-28 | The Regents Of The University Of California | Controlled multi-holes electroporation |
WO2009112952A2 (en) | 2008-03-12 | 2009-09-17 | Cellectricon Ab | Apparatus and method for tip alignment in multiwell plates |
ITCO20080016A1 (it) * | 2008-04-22 | 2009-10-23 | Giuseppe Caccia | Manipolo per elettroporazione di prodotti farmacologici e/o naturali e/o estetici su strati cutanei a spessore contenuto |
DE102008045830A1 (de) | 2008-09-05 | 2010-03-11 | Cinogy Gmbh | Verfahren zur Behandlung eines lebende Zellen enthaltenden biologischen Materials |
WO2010064991A1 (en) * | 2008-12-01 | 2010-06-10 | Nanyang Polytechnic | Electroporation apparatus and method |
KR101760705B1 (ko) | 2009-11-13 | 2017-07-24 | 인튜어티브 서지컬 오퍼레이션즈 인코포레이티드 | 독립적으로 회전하는 부재 내의 병렬 구동 샤프트들을 위한 모터 연접부 |
EP2651505A4 (de) * | 2010-12-15 | 2014-06-11 | Old Dominion Univ Res Found | Elektroporationsinduzierte elektrosensibilisierung |
CN105132284B (zh) * | 2011-05-13 | 2018-04-03 | 加利福尼亚大学董事会 | 用于选择性转染细胞的光热衬底 |
WO2013006343A1 (en) * | 2011-07-01 | 2013-01-10 | Beckman Coulter, Inc. | Low carryover liquid handling probe for an automated analyzer |
JP6035948B2 (ja) * | 2011-08-04 | 2016-11-30 | 日本精工株式会社 | 圧電アクチュエータ及びマニピュレータ |
CN102872531B (zh) * | 2011-09-28 | 2014-11-19 | 上海交通大学 | 一种电渗流可控输药芯片电渗驱动单元的制备方法 |
CN102335479B (zh) * | 2011-09-28 | 2013-03-13 | 上海交通大学 | 植入式微型电渗流可控输药芯片及其制备方法 |
AU2012326203B2 (en) | 2011-10-17 | 2017-11-30 | Massachusetts Institute Of Technology | Intracellular delivery |
CA2905999A1 (en) | 2013-03-15 | 2014-09-25 | The Regents Of The University Of California | High-throughput cargo delivery into live cells using photothermal platforms |
WO2014186697A2 (en) * | 2013-05-16 | 2014-11-20 | Advanced Liquid Logic, Inc. | Droplet actuator for electroporation and transforming cells |
WO2015023982A1 (en) | 2013-08-16 | 2015-02-19 | Massachusetts Institute Of Technology | Selective delivery of material to cells |
JP6839073B2 (ja) | 2014-03-28 | 2021-03-03 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California | 多孔質支持体上の細胞への大きなカーゴの効率的な送達 |
WO2016011059A1 (en) * | 2014-07-14 | 2016-01-21 | President And Fellows Of Harvard College | Drug cocktail analyses using microscale vortex-assisted electroporation |
US20170183644A1 (en) * | 2014-07-14 | 2017-06-29 | President And Fellows Of Harvard College | Drug cocktail analyses using microscale vortex assisted electroporation |
PL226157B1 (pl) | 2014-10-21 | 2017-06-30 | Inst Tech Materiałów Elektronicznych | Mikrosonda do elektroporacji selektywnej i sposob wytwarzania takiej mikrosondy |
RU2739794C2 (ru) | 2014-10-31 | 2020-12-28 | Массачусетс Инститьют Оф Текнолоджи | Доставка биомолекул в клетки иммунной системы |
CN107002089B (zh) | 2014-11-14 | 2021-09-07 | 麻省理工学院 | 化合物和组合物向细胞中的破坏和场实现的递送 |
KR102428464B1 (ko) * | 2014-12-28 | 2022-08-03 | 주식회사 펨토바이오메드 | 세포에 물질을 주입하여 세포를 변환시키는 방법 |
EP3037518B1 (de) | 2014-12-28 | 2020-05-06 | Femtobiomed Inc. | Vorrichtung zum einbringen von material in eine zelle |
EP3037517A1 (de) * | 2014-12-28 | 2016-06-29 | Femtofab Co., Ltd. | Verfahren zur modifizierung einer zelle durch einführung eines materials in die zelle |
CA2971626A1 (en) | 2015-01-12 | 2016-07-21 | Massachusetts Institute Of Technology | Gene editing through microfluidic delivery |
CN104536186B (zh) * | 2015-01-13 | 2017-12-08 | 合肥鑫晟光电科技有限公司 | 一种识别装置和对位*** |
US10167502B2 (en) | 2015-04-03 | 2019-01-01 | Fluxion Biosciences, Inc. | Molecular characterization of single cells and cell populations for non-invasive diagnostics |
US10987670B2 (en) | 2015-04-14 | 2021-04-27 | President And Fellows Of Harvard College | Electrode array for vortex-assisted electroporation |
CA2988996A1 (en) | 2015-07-09 | 2017-01-12 | Massachusetts Institute Of Technology | Delivery of materials to anucleate cells |
US11884960B2 (en) * | 2019-08-16 | 2024-01-30 | Terragene Llc | Biological indicator for determining the efficacy of a steam or heat sterilization process and its method of use |
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EP1448770A1 (de) | 2001-11-27 | 2004-08-25 | Cellectricon AB | Verfahren zur kombinierten sequentiellen zuführung von agentien und elektroporation für zellstrukturen und verwendung davon |
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WO2004034436A2 (en) | 2002-10-09 | 2004-04-22 | Cellectricon Ab | Method for interfacing macroscale components to microscale devices |
US8232074B2 (en) | 2002-10-16 | 2012-07-31 | Cellectricon Ab | Nanoelectrodes and nanotips for recording transmembrane currents in a plurality of cells |
US20040181343A1 (en) | 2002-11-01 | 2004-09-16 | Cellectricon Ab | Computer program products and systems for rapidly changing the solution environment around sensors |
-
2002
- 2002-11-27 EP EP02789118A patent/EP1448770A1/de not_active Withdrawn
- 2002-11-27 AU AU2002365542A patent/AU2002365542A1/en not_active Abandoned
- 2002-11-27 JP JP2003547603A patent/JP2005510237A/ja active Pending
- 2002-11-27 AT AT02791153T patent/ATE350471T1/de not_active IP Right Cessation
- 2002-11-27 EP EP02791153A patent/EP1448771B1/de not_active Expired - Lifetime
- 2002-11-27 US US10/496,214 patent/US20050026283A1/en not_active Abandoned
- 2002-11-27 CA CA002468424A patent/CA2468424A1/en not_active Abandoned
- 2002-11-27 DE DE60217393T patent/DE60217393T2/de not_active Expired - Lifetime
- 2002-11-27 US US10/496,227 patent/US20050019921A1/en not_active Abandoned
- 2002-11-27 CA CA002468511A patent/CA2468511A1/en not_active Abandoned
- 2002-11-27 WO PCT/SE2002/002192 patent/WO2003046170A1/en active Search and Examination
- 2002-11-27 JP JP2003547602A patent/JP4842512B2/ja not_active Expired - Fee Related
- 2002-11-27 AU AU2002353741A patent/AU2002353741A1/en not_active Abandoned
- 2002-11-27 WO PCT/SE2002/002193 patent/WO2003046171A1/en active Search and Examination
-
2008
- 2008-06-09 US US12/157,369 patent/US8338150B2/en not_active Expired - Fee Related
-
2009
- 2009-01-21 US US12/321,391 patent/US8268555B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP4842512B2 (ja) | 2011-12-21 |
US8268555B2 (en) | 2012-09-18 |
AU2002353741A1 (en) | 2003-06-10 |
JP2005510236A (ja) | 2005-04-21 |
US20050019921A1 (en) | 2005-01-27 |
EP1448770A1 (de) | 2004-08-25 |
WO2003046171A1 (en) | 2003-06-05 |
WO2003046170A1 (en) | 2003-06-05 |
US8338150B2 (en) | 2012-12-25 |
CA2468511A1 (en) | 2003-06-05 |
US20100159439A1 (en) | 2010-06-24 |
EP1448771A1 (de) | 2004-08-25 |
DE60217393D1 (de) | 2007-02-15 |
AU2002365542A1 (en) | 2003-06-10 |
CA2468424A1 (en) | 2003-06-05 |
JP2005510237A (ja) | 2005-04-21 |
US20050026283A1 (en) | 2005-02-03 |
DE60217393T2 (de) | 2007-10-18 |
EP1448771B1 (de) | 2007-01-03 |
US20090092963A1 (en) | 2009-04-09 |
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