ATE34982T1 - 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxochinol n-3-carbonsaeure-derivate und 7-(pyrrol-1-yl)-1ethyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3carbons|ure-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel. - Google Patents

7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxochinol n-3-carbonsaeure-derivate und 7-(pyrrol-1-yl)-1ethyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3carbons|ure-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.

Info

Publication number
ATE34982T1
ATE34982T1 AT84401391T AT84401391T ATE34982T1 AT E34982 T1 ATE34982 T1 AT E34982T1 AT 84401391 T AT84401391 T AT 84401391T AT 84401391 T AT84401391 T AT 84401391T AT E34982 T1 ATE34982 T1 AT E34982T1
Authority
AT
Austria
Prior art keywords
dihydro
pyrrol
derivatives
ethyl
oxo
Prior art date
Application number
AT84401391T
Other languages
English (en)
Inventor
Soler Jose Esteve
Original Assignee
Provesan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8311250A external-priority patent/FR2548664B1/fr
Application filed by Provesan Sa filed Critical Provesan Sa
Application granted granted Critical
Publication of ATE34982T1 publication Critical patent/ATE34982T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT84401391T 1983-07-06 1984-06-29 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxochinol n-3-carbonsaeure-derivate und 7-(pyrrol-1-yl)-1ethyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3carbons|ure-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel. ATE34982T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8311250A FR2548664B1 (fr) 1983-07-06 1983-07-06 Derives 7-(pyrrol-l-yl) des acides l-ethyl-1,4-dihydro-4-oxoquinoleine-3-carboxyliques et l-ethyl-1,4-dihydro-4-oxo-(1,8-naphtyridine)-3-carboxyliques substitues, leur preparation et leur application en tant que medicaments
FR8402145A FR2559484B2 (fr) 1983-07-06 1984-02-13 Nouveau derive 7-(pyrrol-1-yl) de l'acide 1-ethyl-1,4-dihydro-4-oxo-(1,8-naphtyridin)-3-carboxylique, sa preparation et son application en tant que medicament
EP84401391A EP0134165B1 (de) 1983-07-06 1984-06-29 7-(Pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxochinolin-3-carbonsäure-Derivate und 7-(Pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3-carbonsäure-Derivate, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ATE34982T1 true ATE34982T1 (de) 1988-06-15

Family

ID=26223521

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84401391T ATE34982T1 (de) 1983-07-06 1984-06-29 7-(pyrrol-1-yl)-1-ethyl-1,4-dihydro-4-oxochinol n-3-carbonsaeure-derivate und 7-(pyrrol-1-yl)-1ethyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3carbons|ure-derivate, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel.

Country Status (21)

Country Link
US (1) US4552882A (de)
EP (1) EP0134165B1 (de)
KR (1) KR880002355B1 (de)
AT (1) ATE34982T1 (de)
AU (1) AU564326B2 (de)
BR (1) BR8403342A (de)
CA (1) CA1256876A (de)
CS (1) CS244139B2 (de)
DD (1) DD223150A5 (de)
DE (1) DE3471934D1 (de)
DK (1) DK163126C (de)
ES (1) ES8503335A1 (de)
FR (1) FR2559484B2 (de)
GR (1) GR81646B (de)
HK (1) HK10491A (de)
HU (1) HU189916B (de)
MX (1) MX156436A (de)
NO (1) NO163329C (de)
PL (1) PL143730B1 (de)
PT (1) PT78854B (de)
YU (1) YU43577B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2574404B1 (fr) * 1984-12-12 1987-04-24 Provesan Sa Derives 1-substitues de l'acide 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoleine-3-carboxylique, leur preparation et leur application en tant que medicaments
DE3519286A1 (de) * 1985-05-30 1986-12-04 Bayer Ag, 5090 Leverkusen 7-azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3- chinolincarbonsaeuren und -1,8-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4692454A (en) * 1986-02-03 1987-09-08 Warner-Lambert Company Opthalmic use of quinolone antibiotics
DE3615767A1 (de) * 1986-05-10 1987-11-12 Bayer Ag Verfahren zur herstellung von 4-hydroxy-chinolin-3-carbonsaeuren
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
US5262417A (en) * 1988-12-06 1993-11-16 The Upjohn Company Antibacterial quinolone compounds
ES2051225B1 (es) * 1992-07-23 1994-12-16 Esteve Quimica Sa Procedimiento de preparacion del acido 1-etil-6-fluoro-7-(pirrol-1-il) -1,4-dihidro-4-oxo-3-quinoleincarboxilico.
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息***
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
PT3395372T (pt) 2009-02-20 2022-05-05 Enhanx Biopharm Inc Sistema de entrega de medicamentos à base de glutationa
WO2010129819A2 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN104803975A (zh) * 2015-04-24 2015-07-29 河南大学 一种氨甲基***取代的二氟喹诺酮羧酸类衍生物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2362553A1 (de) * 1972-12-18 1974-06-20 Dainippon Pharmaceutical Co Neue piperazinderivate
JPS5233694A (en) * 1975-09-09 1977-03-14 Dai Ichi Seiyaku Co Ltd Process for preparation of 6_nitro-1,8-naphthyridine derivatives
AR223983A1 (es) * 1978-08-25 1981-10-15 Dainippon Pharmaceutical Co Un procedimiento para-preparar derivados de acido 6-halogeno-4-oxo-7-(1-piperazinil)-1,8-naftiridin-3-carboxilico
JPS5649382A (en) * 1979-09-28 1981-05-02 Dainippon Pharmaceut Co Ltd 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt

Also Published As

Publication number Publication date
KR880002355B1 (ko) 1988-10-29
CS528584A2 (en) 1985-08-31
FR2559484A2 (fr) 1985-08-16
HU189916B (en) 1986-08-28
PT78854B (fr) 1986-10-23
DE3471934D1 (en) 1988-07-14
DD223150A5 (de) 1985-06-05
KR850001198A (ko) 1985-03-16
YU43577B (en) 1989-08-31
MX156436A (es) 1988-08-22
CS244139B2 (en) 1986-07-17
HK10491A (en) 1991-02-13
BR8403342A (pt) 1985-06-18
FR2559484B2 (fr) 1986-09-26
PT78854A (fr) 1984-08-01
DK331384A (da) 1985-01-07
AU564326B2 (en) 1987-08-06
EP0134165B1 (de) 1988-06-08
EP0134165A2 (de) 1985-03-13
DK331384D0 (da) 1984-07-05
YU119084A (en) 1986-12-31
HUT34482A (en) 1985-03-28
ES533749A0 (es) 1985-03-01
AU2942584A (en) 1985-01-10
PL248545A1 (en) 1985-07-16
NO163329C (no) 1990-05-09
EP0134165A3 (en) 1985-10-09
PL143730B1 (en) 1988-03-31
DK163126B (da) 1992-01-20
NO163329B (no) 1990-01-29
CA1256876A (en) 1989-07-04
NO842717L (no) 1985-01-07
DK163126C (da) 1992-06-15
US4552882A (en) 1985-11-12
GR81646B (de) 1984-12-11
ES8503335A1 (es) 1985-03-01

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