ATE342729T1 - Modifizierter tumor-nekrosefaktor - Google Patents

Modifizierter tumor-nekrosefaktor

Info

Publication number
ATE342729T1
ATE342729T1 AT98904563T AT98904563T ATE342729T1 AT E342729 T1 ATE342729 T1 AT E342729T1 AT 98904563 T AT98904563 T AT 98904563T AT 98904563 T AT98904563 T AT 98904563T AT E342729 T1 ATE342729 T1 AT E342729T1
Authority
AT
Austria
Prior art keywords
tnf
necrosis factor
tumor necrosis
modified tumor
range
Prior art date
Application number
AT98904563T
Other languages
English (en)
Inventor
Mike A Clark
Original Assignee
Phoenix Pharmacologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phoenix Pharmacologics Inc filed Critical Phoenix Pharmacologics Inc
Application granted granted Critical
Publication of ATE342729T1 publication Critical patent/ATE342729T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/525Tumour necrosis factor [TNF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/14Lymphokine; related peptides
    • Y10S930/144Tumor necrosis factor
AT98904563T 1997-01-15 1998-01-15 Modifizierter tumor-nekrosefaktor ATE342729T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3552197P 1997-01-15 1997-01-15
US681098A 1998-01-14 1998-01-14

Publications (1)

Publication Number Publication Date
ATE342729T1 true ATE342729T1 (de) 2006-11-15

Family

ID=26676095

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98904563T ATE342729T1 (de) 1997-01-15 1998-01-15 Modifizierter tumor-nekrosefaktor

Country Status (11)

Country Link
US (1) US7785579B2 (de)
EP (1) EP1007082B1 (de)
JP (1) JP4295831B2 (de)
CN (1) CN1168495C (de)
AT (1) ATE342729T1 (de)
AU (1) AU725133B2 (de)
CA (1) CA2277757C (de)
DE (1) DE69836222T2 (de)
DK (1) DK1007082T3 (de)
ES (1) ES2275300T3 (de)
WO (1) WO1998031383A1 (de)

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CN1315351A (zh) * 2000-03-24 2001-10-03 上海博德基因开发有限公司 一种新的多肽——人一种组织或发育阶段特异转录因子相关因子11和编码这种多肽的多核苷酸
US7635680B2 (en) 2001-02-21 2009-12-22 Alavita Pharmaceuticals, Inc. Attenuation of reperfusion injury
US7635676B2 (en) 2001-02-21 2009-12-22 Alavita Pharmaccuticals, Inc. Modified annexin proteins and methods for their use in organ transplantation
ES2286247T3 (es) * 2001-02-21 2007-12-01 Alavita Pharmaceuticals, Inc. Proteinas anexinicas modificacdas y tratamiento de la trombosis.
US7645739B2 (en) 2001-02-21 2010-01-12 Alavita Pharmaceuticals, Inc. Modified annexin compositions and methods of using same
EP1234583A1 (de) * 2001-02-23 2002-08-28 F. Hoffmann-La Roche Ag PEG-Konjugate des HGF-NK4
NZ541365A (en) 2002-12-27 2009-09-25 Diobex Inc Compositions and methods for the prevention and control of insulin-induced hypoglycemia
US7655618B2 (en) 2002-12-27 2010-02-02 Diobex, Inc. Compositions and methods for the prevention and control of insulin-induced hypoglycemia
US7432331B2 (en) 2002-12-31 2008-10-07 Nektar Therapeutics Al, Corporation Hydrolytically stable maleimide-terminated polymers
KR101025143B1 (ko) 2002-12-31 2011-04-01 넥타르 테라퓨틱스 가수분해상으로 안정한 말레이미드-종결 중합체
WO2005056636A2 (en) 2003-12-03 2005-06-23 Nektar Therapeutics Al, Corporation Method of preparing maleimide functionalized polymers
JP4877225B2 (ja) * 2005-02-18 2012-02-15 日油株式会社 ポリオキシアルキレン誘導体
US8148123B2 (en) 2005-04-11 2012-04-03 Savient Pharmaceuticals, Inc. Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase
PL3321359T3 (pl) 2005-04-11 2021-06-28 Horizon Pharma Rheumatology Llc Wariantowe postacie oksydazy moczanowej i ich zastosowanie
RU2435847C2 (ru) 2005-04-11 2011-12-10 Савиент Фармасьютикалз, Инк. Вариантная форма урат-оксидазы и ее использование
ES2532804T3 (es) 2006-04-12 2015-03-31 Crealta Pharmaceuticals Llc Purificación de proteínas con tensioactivo catiónico
KR100886783B1 (ko) * 2006-06-12 2009-03-04 성균관대학교산학협력단 N-말단이 수식된 peg-trail 결합체, 이의 제조방법 및 이의 용도
CN101837130B (zh) * 2009-03-20 2013-10-23 北京大学 聚乙二醇-二肽-抗肿瘤药物复合物及其用途
US20100284962A1 (en) * 2009-05-06 2010-11-11 Oncopharmacologics, Inc. Modified tumor necrosis factor-beta
KR101861547B1 (ko) 2009-06-25 2018-07-02 크레알타 파마슈티칼스 엘엘씨 페길화된 유리카아제 치료 중에 혈청 요산을 모니터링하여 주입 반응의 위험성 및 반응의 항체­매개 상실을 예측하는 방법 및 키트
WO2014151836A1 (en) * 2013-03-14 2014-09-25 Ran Biotechnologies, Inc. Methods and materials for microorganism capture
KR102352614B1 (ko) 2013-03-14 2022-01-18 랜 바이오테크놀러지스, 인크. 생물제제의 검출을 위한 방법 및 물질
CN105294852B (zh) * 2015-10-27 2019-06-07 岳阳新华达制药有限公司 聚乙二醇与肿瘤坏死因子α或其类似物的偶联物及其医药用途
WO2017106627A1 (en) 2015-12-17 2017-06-22 The Johns Hopkins University Ameliorating systemic sclerosis with death receptor agonists
WO2017177148A1 (en) 2016-04-07 2017-10-12 The Johns Hopkins University Compositions and methods for treating pancreatitis and pain with death receptor agonists

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Also Published As

Publication number Publication date
DE69836222D1 (de) 2006-11-30
CA2277757C (en) 2008-09-16
DK1007082T3 (da) 2007-02-19
CN1243444A (zh) 2000-02-02
US20060222626A1 (en) 2006-10-05
JP2001511784A (ja) 2001-08-14
EP1007082B1 (de) 2006-10-18
WO1998031383A1 (en) 1998-07-23
CA2277757A1 (en) 1998-07-23
EP1007082A4 (de) 2004-05-12
DE69836222T2 (de) 2007-11-15
EP1007082A1 (de) 2000-06-14
ES2275300T3 (es) 2007-06-01
CN1168495C (zh) 2004-09-29
JP4295831B2 (ja) 2009-07-15
AU6241098A (en) 1998-08-07
US7785579B2 (en) 2010-08-31
AU725133B2 (en) 2000-10-05

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