ATE342053T1 - Formulierungen zur inhalation - Google Patents
Formulierungen zur inhalationInfo
- Publication number
- ATE342053T1 ATE342053T1 AT03737353T AT03737353T ATE342053T1 AT E342053 T1 ATE342053 T1 AT E342053T1 AT 03737353 T AT03737353 T AT 03737353T AT 03737353 T AT03737353 T AT 03737353T AT E342053 T1 ATE342053 T1 AT E342053T1
- Authority
- AT
- Austria
- Prior art keywords
- inhalation formulations
- solvate
- compound
- formula
- formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/066,964 US6750210B2 (en) | 2000-08-05 | 2002-02-04 | Formulation containing novel anti-inflammatory androstane derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE342053T1 true ATE342053T1 (de) | 2006-11-15 |
Family
ID=27732221
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03737353T ATE342053T1 (de) | 2002-02-04 | 2003-02-04 | Formulierungen zur inhalation |
Country Status (8)
Country | Link |
---|---|
US (2) | US6750210B2 (de) |
EP (1) | EP1471896B1 (de) |
JP (1) | JP2005519925A (de) |
AT (1) | ATE342053T1 (de) |
AU (1) | AU2003244450A1 (de) |
DE (1) | DE60308997T2 (de) |
ES (1) | ES2274247T3 (de) |
WO (1) | WO2003066032A1 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
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GB0019172D0 (en) | 2000-08-05 | 2000-09-27 | Glaxo Group Ltd | Novel compounds |
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US6858596B2 (en) * | 2000-08-05 | 2005-02-22 | Smithkline Beecham Corporation | Formulation containing anti-inflammatory androstane derivative |
US6759398B2 (en) * | 2000-08-05 | 2004-07-06 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative |
US6777399B2 (en) * | 2000-08-05 | 2004-08-17 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative compositions |
UA77656C2 (en) | 2001-04-07 | 2007-01-15 | Glaxo Group Ltd | S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent |
HUP0400070A2 (hu) * | 2001-04-30 | 2004-04-28 | Glaxo Group Limited | 17alfa-helyzetben ciklusos észtercsoportot tartalmazó androsztán-17béta-karbotiosav-észter-származékok mint gyulladásgátló szerek, eljárás a vegyületek előállítására és ezeket tartalmazó gyógyszerkészítmények |
JP2005500290A (ja) * | 2001-06-12 | 2005-01-06 | グラクソ グループ リミテッド | 抗炎症性の、17β−カルボチオアートアンドロスタン誘導体である17α複素環エステル |
US20030105162A1 (en) * | 2001-08-21 | 2003-06-05 | Celluar Sciences, Inc. | Method for treating bronchial constriction and bronchospasm |
GB0125259D0 (en) * | 2001-10-20 | 2001-12-12 | Glaxo Group Ltd | Novel compounds |
US20050175545A1 (en) * | 2002-02-04 | 2005-08-11 | Keith Biggadike | Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist |
GB0202635D0 (en) * | 2002-02-05 | 2002-03-20 | Glaxo Wellcome Mfg Pte Ltd | Formulation containing novel anti-inflammatory androstane derivative |
ATE453421T1 (de) * | 2002-05-09 | 2010-01-15 | Glaxo Group Ltd | Flüssigkeit abgebende vorrichtung |
GB0217798D0 (en) * | 2002-08-01 | 2002-09-11 | Glaxo Group Ltd | A fluid dispensing device |
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AU2004287261B8 (en) | 2003-11-03 | 2011-01-27 | Glaxo Group Limited | A fluid dispensing device |
GB0405477D0 (en) * | 2004-03-11 | 2004-04-21 | Glaxo Group Ltd | A fluid dispensing device |
EP1699847B1 (de) * | 2003-12-30 | 2011-04-13 | 3M Innovative Properties Company | Herstellungsverfahren von medizinischen zusammensetzungen |
AU2005290068A1 (en) * | 2004-09-24 | 2006-04-06 | 3M Innovative Properties Company | Medicinal aerosol formulations and methods of synthesizing ingredients therefor |
EP1824543B1 (de) * | 2004-12-15 | 2013-01-23 | 3M Innovative Properties Company | Elastomere dichtungen zur verwendung in medizinischen aerosolvorrichtungen |
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GB0507224D0 (en) * | 2005-04-09 | 2005-05-18 | Glaxo Group Ltd | A fluid dispensing device |
GB0604319D0 (en) * | 2006-03-03 | 2006-04-12 | Optinose As | Nasal delivery |
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US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
TWI557136B (zh) * | 2007-06-12 | 2016-11-11 | Ac免疫公司 | 特異性結合β-類澱粉蛋白之抗體及相關核酸分子、表現載體、細胞、組合物、套組、方法及用途 |
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EP2598882B1 (de) | 2010-07-30 | 2017-07-26 | AC Immune S.A. | Sichere und funktionelle humanisierte antikörper für die verwendung in der behandlung von einer amyloidose |
AR083115A1 (es) | 2010-09-30 | 2013-01-30 | Theravance Inc | Sales oxalato cristalinas de un compuesto diamida |
MX368835B (es) * | 2013-12-30 | 2019-10-18 | Chiesi Farm Spa | Composición combinada de bromuro de glicopirronio y formoterol en solución estable presurizada para aerosol. |
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CA2412376A1 (en) | 2000-07-26 | 2002-01-31 | Onkar N. Singh | Pharmaceutical suspension compositions lacking a polymeric suspending agent |
AU2001275760B2 (en) | 2000-08-05 | 2005-03-17 | Glaxo Group Limited | 6.alpha., 9.alpha.-difluoro-17.alpha.-'(2-furanylcarboxyl) oxy!-11.beta.-hydroxy-16.alpha.-methyl-3-oxo-androst-1,4,-diene-17-carbothioic acid S-fluoromethyl ester as an anti-inflammatory agent |
AR032362A1 (es) | 2000-08-14 | 2003-11-05 | Glaxo Group Ltd | Formulacion topica estable de una emulsion de aceite en agua y proceso para su preparacion |
AU2001290146A1 (en) | 2000-09-29 | 2002-04-08 | Glaxo Group Limited | Compounds useful in the treatment of inflammatory diseases |
US20020132803A1 (en) | 2001-01-05 | 2002-09-19 | Mahendra Dedhiya | Fluticasone suspension formulation, spray pattern method, and nasal spray apparatus |
GB0103630D0 (en) | 2001-02-14 | 2001-03-28 | Glaxo Group Ltd | Chemical compounds |
EP1366025B1 (de) | 2001-03-08 | 2007-06-27 | Glaxo Group Limited | Agonisten von beta-adrenorezeptoren |
ATE381537T1 (de) | 2001-03-22 | 2008-01-15 | Glaxo Group Ltd | Formanilid-derivative als beta2-adrenorezeptor- agonisten |
UA77656C2 (en) | 2001-04-07 | 2007-01-15 | Glaxo Group Ltd | S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent |
-
2002
- 2002-02-04 US US10/066,964 patent/US6750210B2/en not_active Expired - Fee Related
-
2003
- 2003-02-04 AU AU2003244450A patent/AU2003244450A1/en not_active Abandoned
- 2003-02-04 ES ES03737353T patent/ES2274247T3/es not_active Expired - Lifetime
- 2003-02-04 WO PCT/GB2003/000460 patent/WO2003066032A1/en not_active Application Discontinuation
- 2003-02-04 US US10/503,396 patent/US20050130947A1/en not_active Abandoned
- 2003-02-04 EP EP03737353A patent/EP1471896B1/de not_active Revoked
- 2003-02-04 AT AT03737353T patent/ATE342053T1/de not_active IP Right Cessation
- 2003-02-04 JP JP2003565456A patent/JP2005519925A/ja active Pending
- 2003-02-04 DE DE60308997T patent/DE60308997T2/de not_active Revoked
Also Published As
Publication number | Publication date |
---|---|
AU2003244450A1 (en) | 2003-09-02 |
DE60308997D1 (de) | 2006-11-23 |
US6750210B2 (en) | 2004-06-15 |
JP2005519925A (ja) | 2005-07-07 |
US20050130947A1 (en) | 2005-06-16 |
DE60308997T2 (de) | 2007-08-30 |
EP1471896B1 (de) | 2006-10-11 |
US20020173496A1 (en) | 2002-11-21 |
WO2003066032A1 (en) | 2003-08-14 |
EP1471896A1 (de) | 2004-11-03 |
ES2274247T3 (es) | 2007-05-16 |
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