ATE340869T1 - Massenmarkierte hybridisierungssonden - Google Patents

Massenmarkierte hybridisierungssonden

Info

Publication number
ATE340869T1
ATE340869T1 AT98900611T AT98900611T ATE340869T1 AT E340869 T1 ATE340869 T1 AT E340869T1 AT 98900611 T AT98900611 T AT 98900611T AT 98900611 T AT98900611 T AT 98900611T AT E340869 T1 ATE340869 T1 AT E340869T1
Authority
AT
Austria
Prior art keywords
hybridization probe
mass
base sequence
mass marked
marked hybridization
Prior art date
Application number
AT98900611T
Other languages
English (en)
Inventor
Guenter Schmidt
Andrew Hugin Thompson
Robert Alexander Wal Johnstone
Original Assignee
Xzillion Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9700746.2A external-priority patent/GB9700746D0/en
Priority claimed from GBGB9718255.4A external-priority patent/GB9718255D0/en
Priority claimed from GBGB9726953.4A external-priority patent/GB9726953D0/en
Application filed by Xzillion Gmbh & Co Kg filed Critical Xzillion Gmbh & Co Kg
Application granted granted Critical
Publication of ATE340869T1 publication Critical patent/ATE340869T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6872Methods for sequencing involving mass spectrometry
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • C12Q1/6874Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Discharge Heating (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Surgical Instruments (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
AT98900611T 1997-01-15 1998-01-15 Massenmarkierte hybridisierungssonden ATE340869T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9700746.2A GB9700746D0 (en) 1996-10-04 1997-01-15 Hybridisation probes
GBGB9718255.4A GB9718255D0 (en) 1996-10-04 1997-08-28 Hybridisation probes
GBGB9726953.4A GB9726953D0 (en) 1997-12-19 1997-12-19 Hybridisation probes

Publications (1)

Publication Number Publication Date
ATE340869T1 true ATE340869T1 (de) 2006-10-15

Family

ID=27268674

Family Applications (2)

Application Number Title Priority Date Filing Date
AT03076965T ATE374836T1 (de) 1997-01-15 1998-01-15 Massenmarkierte hybridisierungssonden
AT98900611T ATE340869T1 (de) 1997-01-15 1998-01-15 Massenmarkierte hybridisierungssonden

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT03076965T ATE374836T1 (de) 1997-01-15 1998-01-15 Massenmarkierte hybridisierungssonden

Country Status (10)

Country Link
EP (2) EP0979305B1 (de)
JP (3) JP3884087B2 (de)
CN (1) CN100434531C (de)
AT (2) ATE374836T1 (de)
AU (1) AU725966B2 (de)
CA (2) CA2277786A1 (de)
DE (2) DE69838519T2 (de)
IL (1) IL130885A (de)
NZ (1) NZ336769A (de)
WO (1) WO1998031830A1 (de)

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9707980D0 (en) 1997-04-21 1997-06-11 Brax Genomics Ltd Characterising DNA
ES2200355T3 (es) * 1997-07-22 2004-03-01 Qiagen Genomics Inc Metodos y composiciones para analizar acidos nucleicos por espectrometria de masas.
GB9718921D0 (en) * 1997-09-05 1997-11-12 Brax Genomics Ltd Catalytically generated mass labels
NZ503289A (en) * 1997-09-15 2002-11-26 Xzillion Gmbh & Co Kg Characterising nucleic acid fragments by mass spectrometry
WO1999029898A2 (de) * 1997-12-05 1999-06-17 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zur identifikation von nucleinsäuren durch matrix-assistierte laser desorptions/ionisations massenspektrometrie
GB9815164D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds for mass spectrometry
GB9815166D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds for mass spectrometry
GB9815163D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds
GB9823646D0 (en) * 1997-12-19 1998-12-23 Brax Genomics Ltd Compounds for mass spectrometry
WO1999060007A2 (en) * 1998-05-15 1999-11-25 Isis Innovation Limited Libraries of oligomers labelled with different tags
US7399844B2 (en) * 1998-07-09 2008-07-15 Agilent Technologies, Inc. Method and reagents for analyzing the nucleotide sequence of nucleic acids
US6270976B1 (en) 1998-09-15 2001-08-07 Brax Group Limited Characterizing nucleic acid by mass spectrometry
JP3668075B2 (ja) * 1999-10-12 2005-07-06 光夫 板倉 遺伝物質シーケンス決定用懸濁系、その懸濁系を用いた遺伝物質シーケンス決定方法およびその懸濁系を用いたSNPs高速スコアリング方法
US6509157B1 (en) * 1999-11-05 2003-01-21 Roche Molecular Systems, Inc 3 blocked nucleic acid amplification primers
DE19963536C2 (de) * 1999-12-20 2003-04-10 Epigenomics Ag Verfahren zur Analyse von Nukleinsäuresequenzen
JP2001204463A (ja) * 2000-01-27 2001-07-31 Toyo Kohan Co Ltd ヌクレオチド固定用担体
GB0006141D0 (en) 2000-03-14 2000-05-03 Brax Group Ltd Mass labels
KR20040010041A (ko) 2000-05-04 2004-01-31 예일 유니버시티 단백질 활성의 스크리닝을 위한 고밀도 단백질 어레이
AU8356201A (en) 2000-08-11 2002-02-25 Agilix Corp Ultra-sensitive detection systems
AU2002253825B8 (en) 2000-10-19 2007-03-22 Target Discovery, Inc. Mass defect labeling for the determination of oligomer sequences
US20040248098A1 (en) * 2000-12-12 2004-12-09 Hidetoshi Inoko Method of detecting polymorphisms in dna by using mass spectroscopy
US20040121313A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in organs for transplantation
WO2004060278A2 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
EP1425586B1 (de) * 2001-09-14 2007-11-21 Electrophoretics Limited Massenmarker
JP4606028B2 (ja) * 2002-04-04 2011-01-05 エレクトロフォレティクス リミテッド 被分析物の分析方法
JP2004037128A (ja) * 2002-06-28 2004-02-05 Canon Inc マトリクス援助レーザー脱着/イオン化飛行時間型質量分析法による基板上の物質の解析方法
AU2003304026B2 (en) 2002-10-29 2010-03-25 Target Discovery, Inc. Method for increasing ionization efficiency in mass spectroscopy
EP1588145B1 (de) 2003-01-30 2011-07-06 Life Technologies Corporation Verfahren, mixturen, kits und zusammensetzungen bezüglich der analytbestimmung
US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US20120122102A1 (en) 2003-09-11 2012-05-17 Rangarajan Sampath Compositions for use in identification of bacteria
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
JP2005140755A (ja) * 2003-11-10 2005-06-02 Japan Science & Technology Agency 質量分析用プローブ及びそれを用いた質量分析方法
US8163895B2 (en) 2003-12-05 2012-04-24 Ibis Biosciences, Inc. Compositions for use in identification of orthopoxviruses
US20050148087A1 (en) 2004-01-05 2005-07-07 Applera Corporation Isobarically labeled analytes and fragment ions derived therefrom
US7355045B2 (en) 2004-01-05 2008-04-08 Applera Corporation Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof
US20050148771A1 (en) 2004-01-05 2005-07-07 Applera Corporation. Active esters of N-substituted piperazine acetic acids, including isotopically enriched versions thereof
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
DE602005001302T2 (de) 2004-03-01 2008-02-14 Applera Corp., Framingham Bestimmung von analytcharakteristika auf der grundlage von bindungseigenschaften
EP1766659A4 (de) 2004-05-24 2009-09-30 Ibis Biosciences Inc Massenspektrometrie mit selektiver ionenfiltrierung durch digitalen schwellenvergleich
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US20070048752A1 (en) 2004-07-12 2007-03-01 Applera Corporation Mass tags for quantitative analyses
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
AU2005280528B2 (en) 2004-07-30 2010-12-23 Adeza Biomedical Corporation Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin
US20060183238A1 (en) 2005-02-09 2006-08-17 Applera Corporation Amine-containing compound analysis methods
CA2600184A1 (en) 2005-03-03 2006-09-08 Isis Pharmaceuticals, Inc. Compositions for use in identification of adventitious viruses
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
EP1904655A2 (de) 2005-07-21 2008-04-02 Isis Pharmaceuticals, Inc. Verfahren zur raschen identifizierung und quantifizierung von nukleinsäurevarianten
GB0515323D0 (en) 2005-07-26 2005-08-31 Electrophoretics Ltd Mass labels
GB0518585D0 (en) * 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
US8975404B2 (en) 2006-01-24 2015-03-10 Dh Technologies Development Pte. Ltd. Labeling reagents for analyte determination and methods and compounds used in making the same
EP2010679A2 (de) 2006-04-06 2009-01-07 Ibis Biosciences, Inc. Zusammensetzungen für die identifizierung von pilzen
US8236565B2 (en) 2006-05-26 2012-08-07 Dh Technologies Development Pte. Ltd. Tagging reagents and methods for hydroxylated compounds
US11098345B2 (en) 2006-06-05 2021-08-24 California Institute Of Technology Methods for detecting target analytes
US7906341B2 (en) 2006-06-30 2011-03-15 Dh Technologies Development Pte, Ltd. Methods, mixtures, kits and compositions pertaining to analyte determination
US8362242B2 (en) 2006-06-30 2013-01-29 Dh Technologies Development Pte. Ltd. Analyte determination utilizing mass tagging reagents comprising a non-encoded detectable label
US8048626B2 (en) 2006-07-28 2011-11-01 California Institute Of Technology Multiplex Q-PCR arrays
US11525156B2 (en) 2006-07-28 2022-12-13 California Institute Of Technology Multiplex Q-PCR arrays
US11560588B2 (en) 2006-08-24 2023-01-24 California Institute Of Technology Multiplex Q-PCR arrays
EP2064332B1 (de) 2006-09-14 2012-07-18 Ibis Biosciences, Inc. Gezielte gesamtgenomamplifizierung zur identifizierung von krankheitserregern
EP2126132B1 (de) 2007-02-23 2013-03-20 Ibis Biosciences, Inc. Verfahren für schnelle forensische dna-analyse
GB0704764D0 (en) 2007-03-12 2007-04-18 Electrophoretics Ltd Isobarically labelled reagents and methods of their use
WO2008151023A2 (en) 2007-06-01 2008-12-11 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
CN101519698B (zh) * 2008-03-10 2013-05-22 周国华 一种利用序列标签定量测定核酸的方法
WO2010033625A1 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Microplate handling systems and related computer program products and methods
WO2010033627A2 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Sample processing units, systems, and related methods
WO2010033599A2 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, systems, and methods
EP2396803A4 (de) 2009-02-12 2016-10-26 Ibis Biosciences Inc Ionisationssondenanordnungen
US9719083B2 (en) 2009-03-08 2017-08-01 Ibis Biosciences, Inc. Bioagent detection methods
EP2406634A4 (de) 2009-03-10 2013-06-19 Univ Maryland Isobare deuterium-markierungsreagenzien für quantitative analyse
WO2010114842A1 (en) 2009-03-30 2010-10-07 Ibis Biosciences, Inc. Bioagent detection systems, devices, and methods
EP2454000A4 (de) 2009-07-17 2016-08-10 Ibis Biosciences Inc Systeme zur identifizierung von biowirkstoffen
US8950604B2 (en) 2009-07-17 2015-02-10 Ibis Biosciences, Inc. Lift and mount apparatus
WO2011014811A1 (en) 2009-07-31 2011-02-03 Ibis Biosciences, Inc. Capture primers and capture sequence linked solid supports for molecular diagnostic tests
EP2462244B1 (de) 2009-08-06 2016-07-20 Ibis Biosciences, Inc. Basiszusammensetzungen ohne massebestimmung zur nukleinsäureerkennung
ES2628739T3 (es) 2009-10-15 2017-08-03 Ibis Biosciences, Inc. Amplificación por desplazamiento múltiple
WO2011115840A2 (en) 2010-03-14 2011-09-22 Ibis Biosciences, Inc. Parasite detection via endosymbiont detection
US9291597B2 (en) 2010-07-02 2016-03-22 Ventana Medical Systems, Inc. Detecting targets using mass tags and mass spectrometry
US8492163B2 (en) 2011-01-31 2013-07-23 Dh Technologies Development Pte. Ltd. Methods, mixtures, kits and compositions pertaining to analyte determination
US9708647B2 (en) * 2015-03-23 2017-07-18 Insilixa, Inc. Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
US20170089915A1 (en) * 2015-09-30 2017-03-30 Agilent Technologies, Inc. Methods of analyte derivatization and enhanced soft ionization
EP3400444A4 (de) * 2016-01-04 2019-10-16 QuantuMDx Group Limited Entwurf, synthese und verwendung synthetischer nukleotide mit ladungsmassenmarkierungen
WO2017155858A1 (en) 2016-03-07 2017-09-14 Insilixa, Inc. Nucleic acid sequence identification using solid-phase cyclic single base extension
CN113924041A (zh) 2019-03-14 2022-01-11 因斯利克萨公司 基于时间门控的荧光检测的方法和***
WO2022098819A1 (en) * 2020-11-06 2022-05-12 Waters Technologies Corporation Methods and compositions useful for nucleic acid analysis
CN116496335B (zh) * 2023-03-21 2024-03-08 中国药科大学 一种修饰核苷酸及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5547835A (en) * 1993-01-07 1996-08-20 Sequenom, Inc. DNA sequencing by mass spectrometry
GB9315847D0 (en) * 1993-07-30 1993-09-15 Isis Innovation Tag reagent and assay method
US5707807A (en) * 1995-03-28 1998-01-13 Research Development Corporation Of Japan Molecular indexing for expressed gene analysis
JPH11503611A (ja) * 1995-04-11 1999-03-30 トラスティーズ・オブ・ボストン・ユニバーシティ 生体高分子の固相配列決定法
HUP9901856A3 (en) * 1996-01-23 2001-10-29 Rapigene Inc Bothell Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques
GB9618544D0 (en) * 1996-09-05 1996-10-16 Brax Genomics Ltd Characterising DNA

Also Published As

Publication number Publication date
NZ336769A (en) 2001-01-26
IL130885A (en) 2005-05-17
AU725966B2 (en) 2000-10-26
JP2001508307A (ja) 2001-06-26
IL130885A0 (en) 2001-01-28
WO1998031830A1 (en) 1998-07-23
AU5570098A (en) 1998-08-07
DE69836013D1 (de) 2006-11-09
EP0979305A1 (de) 2000-02-16
EP0979305B1 (de) 2006-09-27
CN100434531C (zh) 2008-11-19
CN1250483A (zh) 2000-04-12
CA2277786A1 (en) 1998-07-23
DE69838519D1 (de) 2007-11-15
CA2441655A1 (en) 1998-07-23
DE69838519T2 (de) 2008-07-03
JP2004357697A (ja) 2004-12-24
JP2006208400A (ja) 2006-08-10
ATE374836T1 (de) 2007-10-15
EP1400599B1 (de) 2007-10-03
DE69836013T2 (de) 2007-05-24
EP1400599A1 (de) 2004-03-24
JP3884087B2 (ja) 2007-02-21

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