ATE334974T1 - Aminotetrazolderivate als stickstoffmonoxid- synthaseinhibitoren - Google Patents
Aminotetrazolderivate als stickstoffmonoxid- synthaseinhibitorenInfo
- Publication number
- ATE334974T1 ATE334974T1 AT01104598T AT01104598T ATE334974T1 AT E334974 T1 ATE334974 T1 AT E334974T1 AT 01104598 T AT01104598 T AT 01104598T AT 01104598 T AT01104598 T AT 01104598T AT E334974 T1 ATE334974 T1 AT E334974T1
- Authority
- AT
- Austria
- Prior art keywords
- synthase inhibitors
- nitrogen monoxide
- monoxide synthase
- heterocyclyl radical
- aminotetrazole derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
- C07D257/06—Five-membered rings with nitrogen atoms directly attached to the ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/336,596 US5684008A (en) | 1994-11-09 | 1994-11-09 | Aminotetrazole derivatives useful as nitric oxide synthase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE334974T1 true ATE334974T1 (de) | 2006-08-15 |
Family
ID=23316811
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95937674T ATE205484T1 (de) | 1994-11-09 | 1995-11-08 | Aminotetrazol-derivate verwendbar als stickstoff- oxid-synthase inhibitoren |
AT01104598T ATE334974T1 (de) | 1994-11-09 | 1995-11-08 | Aminotetrazolderivate als stickstoffmonoxid- synthaseinhibitoren |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95937674T ATE205484T1 (de) | 1994-11-09 | 1995-11-08 | Aminotetrazol-derivate verwendbar als stickstoff- oxid-synthase inhibitoren |
Country Status (17)
Country | Link |
---|---|
US (5) | US5684008A (de) |
EP (2) | EP0790987B1 (de) |
JP (1) | JP3278165B2 (de) |
KR (1) | KR970707107A (de) |
CN (1) | CN1065531C (de) |
AT (2) | ATE205484T1 (de) |
AU (1) | AU696527B2 (de) |
BR (1) | BR9509629A (de) |
CA (1) | CA2203237C (de) |
DE (2) | DE69535148T2 (de) |
DK (2) | DK1113011T3 (de) |
ES (2) | ES2164164T3 (de) |
HK (1) | HK1036802A1 (de) |
NZ (1) | NZ296019A (de) |
PT (2) | PT1113011E (de) |
RU (1) | RU2152927C1 (de) |
WO (1) | WO1996015120A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5684008A (en) * | 1994-11-09 | 1997-11-04 | G. D. Searle & Co. | Aminotetrazole derivatives useful as nitric oxide synthase inhibitors |
US5919940A (en) * | 1995-01-20 | 1999-07-06 | British Biotech Pharmaceuticals Limited | Metalloproteinase inhibitors |
US5981511A (en) * | 1996-03-06 | 1999-11-09 | G.D. Searle & Co. | Hydroxyamidino derivatives useful as nitric oxide synthase inhibitors |
US5945408A (en) * | 1996-03-06 | 1999-08-31 | G.D. Searle & Co. | Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors |
US6552052B2 (en) | 1998-06-10 | 2003-04-22 | Monsanto/G.D. Searle | Pyrrolo[2,1-c][1,2,4] thiadiazoles and Pyrollo[2,1-c][1,12,4]oxadiazoles useful as nitric oxide synthase inhibitors |
PL346860A1 (en) * | 1998-09-08 | 2002-03-11 | Monsanto Co | Methods of treating osteoarthritis with inducible nitric oxide synthase inhibitors |
WO2000026195A1 (en) * | 1998-10-30 | 2000-05-11 | G.D. Searle & Co. | Novel amino acid heterocyclic amide derivatives useful as nitric oxide synthase inhibitors |
AU2847200A (en) * | 1999-01-27 | 2000-08-18 | G.D. Searle & Co. | Novel hydroxyamidino carboxylate derivatives useful as nitric oxide synthase inhibitors |
WO2000063195A1 (en) * | 1999-04-19 | 2000-10-26 | G.D. Searle & Co. | Novel heterocyclic amino carbonyl derivatives useful as nitric oxide synthase inhibitors |
AU6216900A (en) * | 1999-07-15 | 2001-02-05 | Monsanto Company | Oligomeric amino acid derivatives useful as nitric oxide synthase inhibitors |
DE60116067T2 (de) | 2000-03-24 | 2006-08-31 | Pharmacia Corp., Chicago | Amidino-verbindungen als hemmstoffe der stickstoffmonoxid-synthase |
US6545170B2 (en) | 2000-04-13 | 2003-04-08 | Pharmacia Corporation | 2-amino-5, 6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors |
US6956131B2 (en) | 2000-04-13 | 2005-10-18 | Pharmacia Corporation | 2-amino-3, 4 heptenoic compounds useful as nitric oxide synthase inhibitors |
US6787668B2 (en) | 2000-04-13 | 2004-09-07 | Pharmacia Corporation | 2-amino-4,5 heptenoic acid derivatives useful as nitric oxide synthase inhibitors |
AR034120A1 (es) * | 2000-04-13 | 2004-02-04 | Pharmacia Corp | Compuesto derivado halogenado del acido 2-amino-4,5 heptenoico, composicion farmaceutica que lo comprende y el uso de dicho compuesto y dicha composicion en la fabricacion de un medicamento para inhibir o modular la sintesis de acido nitrico |
AR032318A1 (es) * | 2000-04-13 | 2003-11-05 | Pharmacia Corp | Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa |
AR030416A1 (es) | 2000-04-13 | 2003-08-20 | Pharmacia Corp | COMPUESTO DERIVADO HALOGENADO DEL ACIDO 2-AMINO-3,4 HEPTENOICO, COMPOSICION FARMACEUTICA QUE LO COMPRENDE Y SU USO EN LA FABRICACION DE UN MEDICAMENTO uTIL COMO INHIBIDOR DE LA OXIDO NITRICO SINTETASA |
TWI290130B (en) | 2000-09-15 | 2007-11-21 | Pharmacia Corp | 2-Amino-2alkyl-5 heptenoic and heptynoic acid derivatives useful as nitric oxide synthase inhibitors |
US7012098B2 (en) * | 2001-03-23 | 2006-03-14 | Pharmacia Corporation | Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers |
US20030109522A1 (en) * | 2001-09-24 | 2003-06-12 | Manning Pamela T. | Ophthalmologic treatment methods using selective iNOS inhibitors |
PL375375A1 (en) * | 2002-08-02 | 2005-11-28 | Pharmacia Corporation | Methods for treatment and prevention of gastrointestinal conditions |
CA2494583C (en) * | 2002-08-23 | 2010-02-02 | Pharmacia Corporation | Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid |
PE20221170A1 (es) * | 2015-01-14 | 2022-07-25 | Chiesi Farm Spa | Formulaciones farmaceuticas que comprenden cangrelor de alta pureza y metodos para la preparacion y uso de los mismos |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3505555A1 (de) * | 1985-02-18 | 1986-09-11 | Behringwerke Ag, 3550 Marburg | Neue oligopeptidylargininolderivate und deren homologe, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel |
US5196450A (en) * | 1985-12-19 | 1993-03-23 | Merrell Dow Pharmaceuticals Inc. | Method of inhibiting protozoal growth |
ZA898440B (en) * | 1988-11-10 | 1990-07-25 | Merrell Dow Pharma | Lactamimides in the treatment of drug-resistant protozoal infections |
US5028627A (en) * | 1989-09-13 | 1991-07-02 | Cornell Research Foundation, Inc. | Method of using arginine derivatives to inhibit systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor |
US5059712A (en) * | 1989-09-13 | 1991-10-22 | Cornell Research Foundation, Inc. | Isolating aminoarginine and use to block nitric oxide formation in body |
GB8929076D0 (en) * | 1989-12-22 | 1990-02-28 | Scras | Treatment of shock by blocking agents of edrf effect or formation |
CA2036770C (en) * | 1990-02-26 | 2003-09-09 | Jeffrey P. Whitten | Inhibitors of nitric oxide biosynthesis |
US5273875A (en) * | 1991-03-22 | 1993-12-28 | Cornell Research Foundation, Inc. | N6 -(hydrazinoiminomethyl)lysine and method of inhibiting nitric oxide formation in body |
US5132453A (en) * | 1991-03-22 | 1992-07-21 | Cornell Research Foundation, Inc. | N6 -(hydrazinoiminomethyl)lysine and method of inhibiting nitric oxide formation in body |
GB9127376D0 (en) * | 1991-12-24 | 1992-02-19 | Wellcome Found | Amidino derivatives |
US5296466A (en) * | 1992-02-19 | 1994-03-22 | Board Of Regents, The University Of Texas System | Inhibition of nitric oxide-mediated hypotension and septic shock with iron-containing hemoprotein |
US5281627A (en) * | 1992-05-28 | 1994-01-25 | Cornell Research Foundation, Inc. | Substituted arginines and substituted homoarginines and use thereof |
AU5704594A (en) * | 1992-12-18 | 1994-07-19 | Wellcome Foundation Limited, The | Pyrimidine, pyridine, pteridinone and indazole derivatives as enzyme inhibitors |
GB9312761D0 (en) * | 1993-06-21 | 1993-08-04 | Wellcome Found | Amino acid derivatives |
US5424447A (en) * | 1993-07-07 | 1995-06-13 | The Medical College Of Wisconsin Research Foundation, Inc. | Heme binding compounds and use thereof |
EP0724435B1 (de) * | 1993-10-21 | 2002-08-14 | G.D. Searle & Co. | Amidino-derivate nützlich als no synthase-hemmer |
US5364881A (en) * | 1993-11-15 | 1994-11-15 | The Medical College Of Wisconsin Research Foundation, Inc. | S-alkyl-isothioureido-amino acids and use thereof |
US5362744A (en) * | 1993-11-22 | 1994-11-08 | Warner-Lambert Company | Tetrazole-substituted urea acat inhibitors |
AU2190895A (en) * | 1994-03-24 | 1995-10-09 | G.D. Searle & Co. | Amidino derivatives useful as nitric oxide synthase inhibitors |
WO1996006076A1 (fr) * | 1994-08-18 | 1996-02-29 | Chugai Seiyaku Kabushiki Kaisha | Derives aminoacides exerçant une activite inhibitrice de la synthetase du monoxyde d'azote |
US5684008A (en) * | 1994-11-09 | 1997-11-04 | G. D. Searle & Co. | Aminotetrazole derivatives useful as nitric oxide synthase inhibitors |
-
1994
- 1994-11-09 US US08/336,596 patent/US5684008A/en not_active Expired - Fee Related
-
1995
- 1995-11-08 DK DK01104598T patent/DK1113011T3/da active
- 1995-11-08 PT PT01104598T patent/PT1113011E/pt unknown
- 1995-11-08 US US08/817,971 patent/US5854251A/en not_active Expired - Fee Related
- 1995-11-08 WO PCT/US1995/014001 patent/WO1996015120A1/en not_active Application Discontinuation
- 1995-11-08 ES ES95937674T patent/ES2164164T3/es not_active Expired - Lifetime
- 1995-11-08 DK DK95937674T patent/DK0790987T3/da active
- 1995-11-08 BR BR9509629A patent/BR9509629A/pt not_active IP Right Cessation
- 1995-11-08 NZ NZ296019A patent/NZ296019A/en not_active IP Right Cessation
- 1995-11-08 DE DE69535148T patent/DE69535148T2/de not_active Expired - Fee Related
- 1995-11-08 AT AT95937674T patent/ATE205484T1/de not_active IP Right Cessation
- 1995-11-08 KR KR1019970703106A patent/KR970707107A/ko not_active Application Discontinuation
- 1995-11-08 EP EP95937674A patent/EP0790987B1/de not_active Expired - Lifetime
- 1995-11-08 JP JP51609696A patent/JP3278165B2/ja not_active Expired - Fee Related
- 1995-11-08 EP EP01104598A patent/EP1113011B1/de not_active Expired - Lifetime
- 1995-11-08 CA CA002203237A patent/CA2203237C/en not_active Expired - Fee Related
- 1995-11-08 AU AU39711/95A patent/AU696527B2/en not_active Ceased
- 1995-11-08 ES ES01104598T patent/ES2269240T3/es not_active Expired - Lifetime
- 1995-11-08 RU RU97109847/04A patent/RU2152927C1/ru not_active IP Right Cessation
- 1995-11-08 CN CN95197112A patent/CN1065531C/zh not_active Expired - Fee Related
- 1995-11-08 AT AT01104598T patent/ATE334974T1/de not_active IP Right Cessation
- 1995-11-08 PT PT95937674T patent/PT790987E/pt unknown
- 1995-11-08 DE DE69522703T patent/DE69522703T2/de not_active Expired - Fee Related
-
1998
- 1998-10-05 US US09/166,036 patent/US5919787A/en not_active Expired - Fee Related
-
1999
- 1999-03-12 US US09/267,266 patent/US6169089B1/en not_active Expired - Fee Related
-
2000
- 2000-10-13 US US09/687,350 patent/US6410542B1/en not_active Expired - Fee Related
-
2001
- 2001-11-06 HK HK01107758A patent/HK1036802A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2152927C1 (ru) | 2000-07-20 |
BR9509629A (pt) | 1998-01-06 |
NZ296019A (en) | 1998-09-24 |
US6410542B1 (en) | 2002-06-25 |
EP0790987A1 (de) | 1997-08-27 |
US6169089B1 (en) | 2001-01-02 |
US5919787A (en) | 1999-07-06 |
DE69522703T2 (de) | 2002-07-11 |
ES2164164T3 (es) | 2002-02-16 |
ES2269240T3 (es) | 2007-04-01 |
AU696527B2 (en) | 1998-09-10 |
KR970707107A (ko) | 1997-12-01 |
EP0790987B1 (de) | 2001-09-12 |
DK0790987T3 (da) | 2001-11-12 |
PT1113011E (pt) | 2006-11-30 |
US5684008A (en) | 1997-11-04 |
DE69535148T2 (de) | 2007-07-05 |
DK1113011T3 (da) | 2006-11-27 |
DE69535148D1 (de) | 2006-09-14 |
JP3278165B2 (ja) | 2002-04-30 |
DE69522703D1 (de) | 2001-10-18 |
CN1065531C (zh) | 2001-05-09 |
AU3971195A (en) | 1996-06-06 |
JPH10508847A (ja) | 1998-09-02 |
EP1113011A1 (de) | 2001-07-04 |
ATE205484T1 (de) | 2001-09-15 |
HK1036802A1 (en) | 2002-01-18 |
CN1171104A (zh) | 1998-01-21 |
US5854251A (en) | 1998-12-29 |
EP1113011B1 (de) | 2006-08-02 |
CA2203237C (en) | 2008-06-03 |
CA2203237A1 (en) | 1996-05-23 |
PT790987E (pt) | 2002-02-28 |
WO1996015120A1 (en) | 1996-05-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1113011 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |