IS3828A - Hliðstæð aðferð til tilreiðslu á nýjum afleiðum thiazolidinone og oxazolidinone sem gagnlegar eru til æðaútvíkkunar - Google Patents

Hliðstæð aðferð til tilreiðslu á nýjum afleiðum thiazolidinone og oxazolidinone sem gagnlegar eru til æðaútvíkkunar

Info

Publication number
IS3828A
IS3828A IS3828A IS3828A IS3828A IS 3828 A IS3828 A IS 3828A IS 3828 A IS3828 A IS 3828A IS 3828 A IS3828 A IS 3828A IS 3828 A IS3828 A IS 3828A
Authority
IS
Iceland
Prior art keywords
thiazolidinone
vasodilatation
similar method
new derivatives
preparing new
Prior art date
Application number
IS3828A
Other languages
English (en)
Other versions
IS1746B (is
Inventor
Ishihara
Saito
Yoshioka
Koike
Miyake
Mizuno
Original Assignee
Sankyo Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Company Limited filed Critical Sankyo Company Limited
Publication of IS3828A publication Critical patent/IS3828A/is
Publication of IS1746B publication Critical patent/IS1746B/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • C07D263/24Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14Oxygen atoms
IS3828A 1991-03-27 1992-03-26 Hliðstæð aðferð til tilreiðslu á nýjum afleiðum thiazolidinone og oxazolidinone sem gagnlegar eru til æðaútvíkkunar IS1746B (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP6308891 1991-03-27
JP10275191 1991-05-08
JP33030491 1991-12-13

Publications (2)

Publication Number Publication Date
IS3828A true IS3828A (is) 1992-09-28
IS1746B IS1746B (is) 2000-07-11

Family

ID=27298042

Family Applications (1)

Application Number Title Priority Date Filing Date
IS3828A IS1746B (is) 1991-03-27 1992-03-26 Hliðstæð aðferð til tilreiðslu á nýjum afleiðum thiazolidinone og oxazolidinone sem gagnlegar eru til æðaútvíkkunar

Country Status (23)

Country Link
US (2) US5298516A (is)
EP (1) EP0506434B1 (is)
JP (1) JPH0780859B2 (is)
KR (1) KR0152097B1 (is)
CN (2) CN1031824C (is)
AT (1) ATE118770T1 (is)
AU (1) AU647599B2 (is)
CA (1) CA2064108C (is)
CZ (1) CZ282529B6 (is)
DE (1) DE69201451T2 (is)
DK (1) DK0506434T3 (is)
ES (1) ES2072095T3 (is)
FI (1) FI106260B (is)
HK (1) HK123595A (is)
HU (2) HU217969B (is)
IE (1) IE67383B1 (is)
IL (1) IL101395A (is)
IS (1) IS1746B (is)
NO (1) NO304311B1 (is)
NZ (1) NZ242154A (is)
PH (1) PH30493A (is)
RU (1) RU2055073C1 (is)
TW (1) TW226015B (is)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3454531B2 (ja) * 1991-11-07 2003-10-06 三共株式会社 ニトロキシアルキルアミド誘導体
WO1994021248A1 (de) * 1993-03-15 1994-09-29 Byk Nederland Bv Verwendung von substituierten alkylnitraten zur behandlung des krankhaft erhöhten augeninnendruckes
DE4429461A1 (de) * 1994-08-19 1996-02-22 Merck Patent Gmbh Adhäsionsrezeptor-Antagonisten
CN1092649C (zh) * 1994-12-15 2002-10-16 三共株式会社 噻唑烷酮化合物或以其作为有效成分的心绞痛治疗剂或预防剂
US5925658A (en) * 1995-03-02 1999-07-20 Sankyo Company, Limited Optically active thiazolidinone derivative
CZ290989B6 (cs) * 1995-03-02 2002-11-13 Sankyo Company, Limited Opticky aktivní thiazolidinonový derivát, prostředek jej obsahující, pouľití tohoto derivátu a způsob jeho přípravy
WO1997000239A1 (fr) * 1995-06-14 1997-01-03 Sankyo Company, Limited Medicament contre l'angine contenant un derive nitroxy comme ingredient actif
BE1010768A3 (nl) * 1996-11-26 1999-01-05 Dsm Nv Een werkwijze voor de bereiding van alpha-aminozuuramiden, alpha-aminozuren en derivaten ervan.
IL120531A (en) 1997-03-26 2006-12-31 Yissum Res Dev Co Nitric oxide donors and pharmaceutical compositions containing them
WO2002069967A1 (fr) * 2001-03-01 2002-09-12 Sankyo Company, Limited Compositions a absorption percutanee
US9457014B2 (en) * 2011-07-28 2016-10-04 Promentis Pharmaceuticals, Inc. Cysteine prodrugs
US10239847B1 (en) 2016-03-03 2019-03-26 Cellactin Method for 2-oxothiazolidine-4-carboxylic acid for cellular glutathione

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200640A (en) * 1976-04-02 1980-04-29 Chugai Seiyaku Kabushiki Kaisha Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use
GB8717068D0 (en) * 1987-07-20 1987-08-26 Fujisawa Pharmaceutical Co Nitric ester derivative
DK0393911T3 (da) * 1989-04-21 1994-10-03 Du Pont Fungicide oxazolidinoner

Also Published As

Publication number Publication date
CZ282529B6 (cs) 1997-08-13
JPH0780859B2 (ja) 1995-08-30
FI921340A (fi) 1992-09-28
AU1312292A (en) 1992-10-01
AU647599B2 (en) 1994-03-24
IL101395A0 (en) 1992-11-15
CN1113435A (zh) 1995-12-20
CZ91692A3 (en) 1993-01-13
IS1746B (is) 2000-07-11
NO921159D0 (no) 1992-03-25
NZ242154A (en) 1993-09-27
CN1096265C (zh) 2002-12-18
ES2072095T3 (es) 1995-07-01
FI921340A0 (fi) 1992-03-26
EP0506434A1 (en) 1992-09-30
CN1031824C (zh) 1996-05-22
DE69201451D1 (de) 1995-03-30
US5356918A (en) 1994-10-18
CN1066067A (zh) 1992-11-11
HU9201033D0 (en) 1992-06-29
DK0506434T3 (da) 1995-07-24
RU2055073C1 (ru) 1996-02-27
EP0506434B1 (en) 1995-02-22
HU211969A9 (en) 1996-01-29
NO304311B1 (no) 1998-11-30
HK123595A (en) 1995-08-04
CA2064108A1 (en) 1992-09-28
TW226015B (is) 1994-07-01
JPH05213910A (ja) 1993-08-24
DE69201451T2 (de) 1995-10-12
IE67383B1 (en) 1996-03-20
FI106260B (fi) 2000-12-29
IE920966A1 (en) 1992-10-07
HU217969B (hu) 2000-05-28
IL101395A (en) 1996-10-16
US5298516A (en) 1994-03-29
ATE118770T1 (de) 1995-03-15
PH30493A (en) 1997-05-28
CA2064108C (en) 2000-09-26
KR0152097B1 (ko) 1998-10-15
KR920018036A (ko) 1992-10-21
HUT68242A (en) 1995-06-28
NO921159L (no) 1992-09-28

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