ATE326484T1 - Monoklonaler antikörper gegen flt4-rezeptor- tyrosinkinase und dessen verwendung zur diagnose und therapie - Google Patents
Monoklonaler antikörper gegen flt4-rezeptor- tyrosinkinase und dessen verwendung zur diagnose und therapieInfo
- Publication number
- ATE326484T1 ATE326484T1 AT95922533T AT95922533T ATE326484T1 AT E326484 T1 ATE326484 T1 AT E326484T1 AT 95922533 T AT95922533 T AT 95922533T AT 95922533 T AT95922533 T AT 95922533T AT E326484 T1 ATE326484 T1 AT E326484T1
- Authority
- AT
- Austria
- Prior art keywords
- diagnosis
- therapy
- monoclonal antibody
- tyrosine kinase
- antibody against
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25775494A | 1994-06-09 | 1994-06-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE326484T1 true ATE326484T1 (de) | 2006-06-15 |
Family
ID=22977612
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95922533T ATE326484T1 (de) | 1994-06-09 | 1995-06-09 | Monoklonaler antikörper gegen flt4-rezeptor- tyrosinkinase und dessen verwendung zur diagnose und therapie |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0807124B1 (de) |
JP (4) | JP3723210B2 (de) |
AT (1) | ATE326484T1 (de) |
AU (1) | AU694524B2 (de) |
CA (1) | CA2192235C (de) |
DE (1) | DE69534996T2 (de) |
DK (1) | DK0807124T3 (de) |
ES (1) | ES2263152T3 (de) |
FI (1) | FI964862A (de) |
MX (1) | MX9606218A (de) |
NO (1) | NO319383B1 (de) |
NZ (1) | NZ288235A (de) |
PT (1) | PT807124E (de) |
WO (1) | WO1995033772A1 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6824777B1 (en) | 1992-10-09 | 2004-11-30 | Licentia Ltd. | Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy |
US6107046A (en) * | 1992-10-09 | 2000-08-22 | Orion Corporation | Antibodies to Flt4, a receptor tyrosine kinase and uses thereof |
US6403088B1 (en) | 1995-08-01 | 2002-06-11 | Helsinki University Licensing, Ltd. | Antibodies reactive with VEGF-C, a ligand for the Flt4 receptor tyrosine kinase (VEGFR-3) |
US6130071A (en) * | 1997-02-05 | 2000-10-10 | Helsinki University Licensing, Ltd. | Vascular endothelial growth factor C (VEGF-C) ΔCys156 protein and gene, and uses thereof |
US6221839B1 (en) | 1994-11-14 | 2001-04-24 | Helsinki University Licensing Ltd. Oy | FIt4 ligand and methods of use |
US6645933B1 (en) | 1995-08-01 | 2003-11-11 | Helsinki University Licensing Ltd. Oy | Receptor ligand VEGF-C |
US6818220B1 (en) | 1994-11-14 | 2004-11-16 | Licentia Ltd. | Vascular endothelial growth factor C (VEGF-C) protein and gene mutants thereof, and uses thereof |
US6245530B1 (en) | 1995-08-01 | 2001-06-12 | Ludwig Institute For Cancer Research | Receptor ligand |
US6361946B1 (en) | 1997-02-05 | 2002-03-26 | Licentia Ltd | Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof |
US7423125B2 (en) | 1995-08-01 | 2008-09-09 | Vegenics Limited | Antibodies to VEGF-C |
DK0848755T4 (da) | 1995-09-08 | 2011-05-23 | Genentech Inc | VEGF relateret protein |
US6100071A (en) | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
US7125714B2 (en) | 1997-02-05 | 2006-10-24 | Licentia Ltd. | Progenitor cell materials and methods |
FR2783325A1 (fr) * | 1998-09-11 | 2000-03-17 | Inst Nat Sante Rech Med | Moyens pour le controle de la regulation negative d'une activation transmise par un rtk |
JP4841724B2 (ja) | 1998-10-09 | 2011-12-21 | ベジェニクス ピーティーワイ リミテッド | 腫瘍イメージングおよび抗腫瘍治療の標的としてのFlt4(VERG−3) |
JP2002540814A (ja) * | 1999-04-13 | 2002-12-03 | ノースウエスト バイオセラピューティクス,インコーポレイティド | 転移性前立腺腫瘍の診断および処置のための方法 |
EP1553414A1 (de) * | 1999-04-13 | 2005-07-13 | Medarex, Inc. | Methoden zur Diagnose und Behandlung metastasierender Prostata-Tumore |
US6927203B1 (en) | 1999-08-17 | 2005-08-09 | Purdue Research Foundation | Treatment of metastatic disease |
US6599717B1 (en) * | 1999-10-01 | 2003-07-29 | Exelixis, Inc. | Invertebrate vascular endothelial growth factor receptor |
CA2435503C (en) * | 2001-01-19 | 2011-02-22 | Ludwig Institute For Cancer Research | Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy |
WO2007138143A2 (es) * | 2006-05-29 | 2007-12-06 | Consejo Superior De Investigaciones Cientificas | Anticuerpos monoclonales anti-colina quinasa alfa y su uso en técnicas analíticas, de diagnóstico del cáncer y en la preparación de medicamentos |
WO2008093246A2 (en) | 2007-02-02 | 2008-08-07 | Vegenics Limited | Vegf receptor antagonist for treating organ transplant alloimmunity and arteriosclerosis |
PT2956476T (pt) | 2013-02-18 | 2020-02-21 | Vegenics Pty Ltd | Moléculas de ligação e usos destas |
WO2014182635A1 (en) | 2013-05-08 | 2014-11-13 | Baldwin Megan E | Biomarkers for age-related macular degeneration (amd) |
CN114262683B (zh) * | 2022-03-01 | 2022-06-17 | 中国科学院动物研究所 | 一种表达vegfr3 d2多肽的细菌制剂及其构建方法和应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0620826A1 (de) * | 1992-01-09 | 1994-10-26 | Helsinki University Holding, Ltd. | Tie, eine neuartiger tyrosinkinase-rezeptor in endothelzellen |
ES2360641T3 (es) * | 1992-10-28 | 2011-06-07 | Genentech, Inc. | Uso de antagonistas del factor de crecimiento endotelial vascular. |
-
1995
- 1995-06-09 AT AT95922533T patent/ATE326484T1/de not_active IP Right Cessation
- 1995-06-09 NZ NZ288235A patent/NZ288235A/xx unknown
- 1995-06-09 EP EP95922533A patent/EP0807124B1/de not_active Expired - Lifetime
- 1995-06-09 PT PT95922533T patent/PT807124E/pt unknown
- 1995-06-09 WO PCT/FI1995/000337 patent/WO1995033772A1/en active IP Right Grant
- 1995-06-09 DK DK95922533T patent/DK0807124T3/da active
- 1995-06-09 CA CA2192235A patent/CA2192235C/en not_active Expired - Lifetime
- 1995-06-09 MX MX9606218A patent/MX9606218A/es unknown
- 1995-06-09 ES ES95922533T patent/ES2263152T3/es not_active Expired - Lifetime
- 1995-06-09 AU AU27388/95A patent/AU694524B2/en not_active Expired
- 1995-06-09 DE DE69534996T patent/DE69534996T2/de not_active Expired - Lifetime
- 1995-06-09 JP JP50041096A patent/JP3723210B2/ja not_active Expired - Fee Related
-
1996
- 1996-12-04 FI FI964862A patent/FI964862A/fi unknown
- 1996-12-06 NO NO19965231A patent/NO319383B1/no unknown
-
2005
- 2005-01-06 JP JP2005001867A patent/JP2005139199A/ja active Pending
-
2009
- 2009-02-04 JP JP2009023515A patent/JP2009102415A/ja active Pending
-
2012
- 2012-06-20 JP JP2012138421A patent/JP2012193191A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2009102415A (ja) | 2009-05-14 |
AU2738895A (en) | 1996-01-04 |
JPH10500858A (ja) | 1998-01-27 |
JP2005139199A (ja) | 2005-06-02 |
NZ288235A (en) | 1999-05-28 |
JP2012193191A (ja) | 2012-10-11 |
MX9606218A (es) | 1998-02-28 |
CA2192235A1 (en) | 1995-12-14 |
FI964862A (fi) | 1997-02-10 |
DK0807124T3 (da) | 2006-08-28 |
NO965231L (no) | 1996-12-06 |
CA2192235C (en) | 2011-02-15 |
NO965231D0 (no) | 1996-12-06 |
NO319383B1 (no) | 2005-07-25 |
WO1995033772A1 (en) | 1995-12-14 |
FI964862A0 (fi) | 1996-12-04 |
PT807124E (pt) | 2006-08-31 |
AU694524B2 (en) | 1998-07-23 |
EP0807124B1 (de) | 2006-05-17 |
ES2263152T3 (es) | 2006-12-01 |
JP3723210B2 (ja) | 2005-12-07 |
DE69534996T2 (de) | 2007-05-10 |
EP0807124A1 (de) | 1997-11-19 |
DE69534996D1 (de) | 2006-06-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE326484T1 (de) | Monoklonaler antikörper gegen flt4-rezeptor- tyrosinkinase und dessen verwendung zur diagnose und therapie | |
PT914345E (pt) | Ligacao de anticorpos a receptores (ccr2) de proteina 1 de quimio-atraccao de monocitos (pqm-1) | |
DE69417417D1 (de) | Monoklonale antikörper gegen den alpha-pdgf-rezeptor und deren verwendungen | |
CA2250141A1 (en) | Monoclonal antibodies specific for the extracellular domain of prostate specific membrane antigen | |
ATE202849T1 (de) | Verwendung von humanem neutrophil-lipocalin(hnl) als diagnostischer marker und anti-hnl- antikörperzubereitung | |
DK0540573T3 (da) | Assay for frit- og kompleksbundet prostataspecifikt antigen (PSA) | |
NO974534D0 (no) | Bestemmelse av cPSA | |
DE69637909D1 (de) | ANTI-Fas-LIGAND ANTIKÖRPER UND TESTMETHODE UNTER VERWENDUNG DERSELBEN | |
TR200103011T2 (tr) | Bulaşıcı sünger tipi ansefalopatilerinin teşhisine yönelik metod. | |
DE3780480D1 (de) | Test fuer menschlichen brustkrebs. | |
NO177463C (no) | STLV-III-beslektede polypeptider, diagnostiske prövesett og in vitro analysefremgangsmåte for påvisning av anti-HIV-2-antistoffer i kroppsvæskepröve | |
FR2795823B1 (fr) | Methodes et kits pour le diagnostic ou le suivi d'une pathologie synoviale ou osteoarticulaire comprenant l'utilisation d'un marqueur specifique de la degradation du tissu synovial | |
DE69229948D1 (de) | hGPIIb-FRAGMENTE UND IHRE VERWENDUNG IN IN-VITRO-VERFAHREN ZUR BESTIMMUNG VON IN VIVO STATTFINDENDEN THROMBOTISCHEN EREIGNISSEN | |
ATE433575T1 (de) | Neurotransmission-störungen | |
DE69523492D1 (de) | Immunoassay-Reagenzien, Testsätze und Verfahren | |
ES2168378T3 (es) | Determinacion de tripsinogeno-2 libre y en forma de complejo. | |
ES2189254T3 (es) | Dosificado inmunologico que permite detectar los anticuerpos igm especificos del citomegalovirus humano. | |
WO1990008956A1 (fr) | Detection d'activateur de facteur tissulaire humain | |
NO20022276D0 (no) | Human neurokinin-B-forlöper fra placenta | |
UA29191A (uk) | Спосіб діагностики плацентарної недостатності |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0807124 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |