ATE321562T1 - Neue polymer zubereitungen enthaltende perluorierte verbindungen zur technischen handhabung von zellen und gewebe bei transplantationen, um den metabolismus und die überlebensrate der zellen zu verbessern, sowie verfahren zu deren herstellung - Google Patents

Neue polymer zubereitungen enthaltende perluorierte verbindungen zur technischen handhabung von zellen und gewebe bei transplantationen, um den metabolismus und die überlebensrate der zellen zu verbessern, sowie verfahren zu deren herstellung

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Publication number
ATE321562T1
ATE321562T1 AT00905533T AT00905533T ATE321562T1 AT E321562 T1 ATE321562 T1 AT E321562T1 AT 00905533 T AT00905533 T AT 00905533T AT 00905533 T AT00905533 T AT 00905533T AT E321562 T1 ATE321562 T1 AT E321562T1
Authority
AT
Austria
Prior art keywords
cells
alginate
glycosaminoglycan
cross
polymerized
Prior art date
Application number
AT00905533T
Other languages
English (en)
Inventor
Christopher Fraker
Luca Inverardi
Marcos Mares-Guia
Camillo Ricordi
Original Assignee
Biomm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomm Inc filed Critical Biomm Inc
Application granted granted Critical
Publication of ATE321562T1 publication Critical patent/ATE321562T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734—Alginic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04—Alginic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/02—Halogenated hydrocarbons

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT00905533T 1999-01-04 2000-01-04 Neue polymer zubereitungen enthaltende perluorierte verbindungen zur technischen handhabung von zellen und gewebe bei transplantationen, um den metabolismus und die überlebensrate der zellen zu verbessern, sowie verfahren zu deren herstellung ATE321562T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11470899P 1999-01-04 1999-01-04

Publications (1)

Publication Number Publication Date
ATE321562T1 true ATE321562T1 (de) 2006-04-15

Family

ID=22356944

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00905533T ATE321562T1 (de) 1999-01-04 2000-01-04 Neue polymer zubereitungen enthaltende perluorierte verbindungen zur technischen handhabung von zellen und gewebe bei transplantationen, um den metabolismus und die überlebensrate der zellen zu verbessern, sowie verfahren zu deren herstellung

Country Status (6)

Country Link
US (1) US6630154B1 (de)
EP (1) EP1146884B1 (de)
AT (1) ATE321562T1 (de)
BR (1) BR0007296A (de)
DE (1) DE60026974T2 (de)
WO (1) WO2000040252A1 (de)

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US8012500B2 (en) * 2000-01-01 2011-09-06 Beta-O2 Technologies Ltd. Implantable device
AU2003234709A1 (en) 2002-04-11 2003-10-27 Carbomer Fluorinated or paramagnetic alginate polymer, annexin paramagnetic conjugate, and their use as contrasting agent in mri
US6911457B2 (en) 2002-04-11 2005-06-28 Carbomer, Inc. Diabetes imaging probes
SG146691A1 (en) 2003-10-08 2008-10-30 Vet Stem Inc Methods of preparing and using stem cell compositions and kits comprising the same
US7109280B2 (en) * 2003-10-29 2006-09-19 Council Of Scientific And Industrial Research Block copolymers and preparation thereof
CA2567578C (en) 2004-06-01 2018-04-24 In Motion Investment, Ltd. In vitro techniques for obtaining stem cells from blood
US7951357B2 (en) * 2004-07-14 2011-05-31 Glusense Ltd. Implantable power sources and sensors
RU2401084C2 (ru) * 2004-07-29 2010-10-10 Юниверсити Оф Майами Гибридное устройство для клеточной терапии
US20060204482A1 (en) * 2005-03-14 2006-09-14 Deolden James Methods of islet isolation and transplantation
TW200734462A (en) 2006-03-08 2007-09-16 In Motion Invest Ltd Regulating stem cells
US20110045077A1 (en) * 2006-11-13 2011-02-24 Gordon Weir Encapsulated pancreatic islet cell products and methods of use thereof
WO2008062417A2 (en) * 2006-11-22 2008-05-29 Beta O2 Technologies Ltd. Protecting algae from body fluids
EP2104492B1 (de) 2006-11-28 2017-11-22 Beta O2 Technologies Ltd. Sauerstoffzufuhr für ein zelltransplantat und vaskularisierung
AU2008214423A1 (en) * 2007-02-02 2008-08-14 Converge Biotech Inc. Therapeutic hybrid implantable devices
US20090017092A1 (en) * 2007-07-12 2009-01-15 Aroop Kumar Dutta Novel Class of Cell-Interactive Material and Process of Preparation of Artificial Tissues of Human and Animal Origin
WO2009031154A2 (en) 2007-09-07 2009-03-12 Beta O2 Technologies Ltd. Air gap for supporting cells
CN105664197A (zh) * 2008-04-24 2016-06-15 麦德托尼克公司 冷电离辐射灭菌
CA2722145A1 (en) 2008-04-24 2009-10-29 Medtronic, Inc. Rehydratable thiolated polysaccharide particles and sponge
CN102065849B (zh) 2008-04-24 2015-04-29 麦德托尼克公司 基于壳聚糖和氧化多糖的保护性凝胶
US9540630B2 (en) * 2008-09-17 2017-01-10 Beta O2 Technologies Ltd. Optimization of alginate encapsulation of islets for transplantation
US9446168B2 (en) 2010-06-07 2016-09-20 Beta-O2 Technologies Ltd. Multiple-layer immune barrier for donor cells
WO2010054325A2 (en) * 2008-11-07 2010-05-14 Kuehnle Agrosystems, Inc. Preservation and composition of bioprocess algae for production of lipids, seedstock, and feed
US8043271B2 (en) * 2008-11-26 2011-10-25 Beta 02 Technologies Ltd. Apparatus for transportation of oxygen to implanted cells
US20100160749A1 (en) * 2008-12-24 2010-06-24 Glusense Ltd. Implantable optical glucose sensing
US9037205B2 (en) 2011-06-30 2015-05-19 Glusense, Ltd Implantable optical glucose sensing
KR101401798B1 (ko) 2011-09-21 2014-05-29 가톨릭대학교 산학협력단 퍼플루오데칼린 교질 입자를 함유하는 알긴산 미세 캡슐 조성물 및 이의 제조 방법
WO2013188626A2 (en) 2012-06-15 2013-12-19 Dow Global Technologies Llc Probiotic-containing particles having improved probiotic stability when in aqueous formulations
US10575765B2 (en) 2014-10-13 2020-03-03 Glusense Ltd. Analyte-sensing device
WO2017183030A1 (en) 2016-04-20 2017-10-26 Glusense Ltd. Fret-based glucose-detection molecules
CN107496953A (zh) * 2017-07-31 2017-12-22 滨州医学院 一种硫酸软骨素的灭菌方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6409594A (en) * 1993-03-16 1994-10-11 Alliance Pharmaceutical Corporation Preservation solution and method for warm organ preservation
US6281341B1 (en) * 1997-04-30 2001-08-28 Biomm, Inc. & University Of Miami Hetero-polysaccharide conjugate and methods of making and using the same

Also Published As

Publication number Publication date
BR0007296A (pt) 2002-02-05
EP1146884A4 (de) 2003-05-28
DE60026974T2 (de) 2007-04-19
DE60026974D1 (de) 2006-05-18
US6630154B1 (en) 2003-10-07
WO2000040252A1 (en) 2000-07-13
EP1146884B1 (de) 2006-03-29
EP1146884A1 (de) 2001-10-24

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