ATE315588T1 - Verfahren zur herstellung von heparin - Google Patents

Verfahren zur herstellung von heparin

Info

Publication number
ATE315588T1
ATE315588T1 AT98942666T AT98942666T ATE315588T1 AT E315588 T1 ATE315588 T1 AT E315588T1 AT 98942666 T AT98942666 T AT 98942666T AT 98942666 T AT98942666 T AT 98942666T AT E315588 T1 ATE315588 T1 AT E315588T1
Authority
AT
Austria
Prior art keywords
producing heparin
heparin
producing
Prior art date
Application number
AT98942666T
Other languages
English (en)
Inventor
Houdenhoven Francois Egber Van
Adriamus Lambertus Mar Sanders
Zutphen Petrus Johannes Jo Van
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE315588T1 publication Critical patent/ATE315588T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT98942666T 1997-07-16 1998-07-09 Verfahren zur herstellung von heparin ATE315588T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97202213 1997-07-16

Publications (1)

Publication Number Publication Date
ATE315588T1 true ATE315588T1 (de) 2006-02-15

Family

ID=8228564

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98942666T ATE315588T1 (de) 1997-07-16 1998-07-09 Verfahren zur herstellung von heparin

Country Status (24)

Country Link
US (1) US6232093B1 (de)
EP (1) EP0996642B1 (de)
JP (1) JP4455680B2 (de)
KR (1) KR100515706B1 (de)
CN (1) CN1109048C (de)
AR (1) AR013223A1 (de)
AT (1) ATE315588T1 (de)
AU (1) AU739225B2 (de)
BR (1) BR9810881B1 (de)
CA (1) CA2294780C (de)
CZ (1) CZ299281B6 (de)
DE (1) DE69833205T2 (de)
DK (1) DK0996642T3 (de)
ES (1) ES2256954T3 (de)
HR (1) HRP980399B1 (de)
HU (1) HU225240B1 (de)
IL (1) IL133363A (de)
NO (1) NO320786B1 (de)
PL (1) PL195526B1 (de)
TR (1) TR200000086T2 (de)
TW (1) TW581814B (de)
UY (1) UY25097A1 (de)
WO (1) WO1999003893A1 (de)
ZA (1) ZA986289B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003225724A1 (en) 2002-03-11 2003-09-29 Momenta Pharmaceuticals, Inc. Analysis of sulfated polysaccharides
NZ537005A (en) 2002-06-19 2008-01-31 Can Technologies Inc Animal feed composition comprising mucosa byproduct
US6933372B2 (en) * 2003-03-07 2005-08-23 Warner-Lambert Company Method to produce a solid form of heparin
CN100425624C (zh) * 2006-05-11 2008-10-15 中国农业大学 一种同步提取肝素钠和猪肠粘膜抗菌肽的方法
CN100439402C (zh) * 2006-10-12 2008-12-03 孙红 采用卵磷脂液膜分离法提取肝素的方法
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
WO2010110654A1 (en) * 2009-03-24 2010-09-30 Van Hessen Bv Method for preparation of heparin from mucosa
US8435795B2 (en) * 2010-01-19 2013-05-07 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
WO2012115952A1 (en) 2011-02-21 2012-08-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
KR101447123B1 (ko) 2014-02-27 2014-10-06 박상협 헤파린의 추출 방법
CN104086672A (zh) * 2014-06-10 2014-10-08 安徽申奥生物科技有限公司 一种粗品肝素钠的生产方法
HUE064469T2 (hu) 2018-07-11 2024-03-28 Ajinomoto Kk Az Enterobacteriaceae családba tartozó baktériumot alkalmazó eljárás alkoholok és aminok enzimatikus szulfurilálására
KR102180261B1 (ko) * 2019-03-19 2020-11-18 중앙대학교 산학협력단 돈육 부산물 유래 헤파린의 추출 방법
KR102104367B1 (ko) 2019-09-02 2020-04-24 팜앤바이오 주식회사 헤파린나트륨의 제조장치 및 제조방법
CN115028757A (zh) * 2022-06-29 2022-09-09 江苏麦德森制药有限公司 一种肝素钠的脱色方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH617963A5 (de) 1973-10-05 1980-06-30 Derivati Organici Lab
HU177887B (en) 1979-03-21 1982-01-28 Richter Gedeon Vegyeszet Process for preparing a raw material containing heparin
EP0421508B1 (de) * 1989-10-04 1993-12-15 Akzo Nobel N.V. Sulfatierte Glykosaminoglykuronane mit antithrombotischer Wirkung.
AU5681094A (en) * 1992-11-30 1994-06-22 Celsus, Inc. Protein hydrolysate derived from mucosal tissue

Also Published As

Publication number Publication date
AU739225B2 (en) 2001-10-04
CN1109048C (zh) 2003-05-21
HRP980399A2 (en) 1999-04-30
EP0996642A1 (de) 2000-05-03
EP0996642B1 (de) 2006-01-11
PL338007A1 (en) 2000-09-25
ES2256954T3 (es) 2006-07-16
AR013223A1 (es) 2000-12-13
ZA986289B (en) 1999-05-04
US6232093B1 (en) 2001-05-15
CA2294780A1 (en) 1999-01-28
UY25097A1 (es) 1999-01-11
CZ2000138A3 (cs) 2000-07-12
TR200000086T2 (tr) 2000-08-21
KR20010014387A (ko) 2001-02-26
PL195526B1 (pl) 2007-09-28
JP4455680B2 (ja) 2010-04-21
WO1999003893A1 (en) 1999-01-28
CN1264391A (zh) 2000-08-23
DE69833205D1 (de) 2006-04-06
NO20000189D0 (no) 2000-01-14
IL133363A0 (en) 2001-04-30
TW581814B (en) 2004-04-01
DE69833205T2 (de) 2006-07-20
HUP0003064A3 (en) 2003-01-28
DK0996642T3 (da) 2006-05-08
AU9071598A (en) 1999-02-10
IL133363A (en) 2005-08-31
NO20000189L (no) 2000-03-14
HRP980399B1 (en) 2003-04-30
BR9810881B1 (pt) 2009-01-13
BR9810881A (pt) 2000-09-26
CZ299281B6 (cs) 2008-06-04
KR100515706B1 (ko) 2005-09-15
CA2294780C (en) 2008-03-04
JP2002508805A (ja) 2002-03-19
HU225240B1 (en) 2006-08-28
NO320786B1 (no) 2006-01-30
HUP0003064A2 (hu) 2000-12-28

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