ATE298748T1 - (1,4')-bipiperidin verbindungen - Google Patents
(1,4')-bipiperidin verbindungenInfo
- Publication number
- ATE298748T1 ATE298748T1 AT01920053T AT01920053T ATE298748T1 AT E298748 T1 ATE298748 T1 AT E298748T1 AT 01920053 T AT01920053 T AT 01920053T AT 01920053 T AT01920053 T AT 01920053T AT E298748 T1 ATE298748 T1 AT E298748T1
- Authority
- AT
- Austria
- Prior art keywords
- bipiperidine
- compounds
- bipiperidine compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0008626A GB0008626D0 (en) | 2000-04-08 | 2000-04-08 | Chemical compounds |
GB0019111A GB0019111D0 (en) | 2000-08-03 | 2000-08-03 | Chemical compounds |
SE0003664A SE0003664D0 (sv) | 2000-10-11 | 2000-10-11 | Chemical compounds |
PCT/SE2001/000751 WO2001077101A1 (en) | 2000-04-08 | 2001-04-05 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE298748T1 true ATE298748T1 (de) | 2005-07-15 |
Family
ID=27255657
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01920053T ATE298748T1 (de) | 2000-04-08 | 2001-04-05 | (1,4')-bipiperidin verbindungen |
AT04020599T ATE407131T1 (de) | 2000-04-08 | 2001-04-05 | Substituierte bipiperidine -zwischenverbindungen und deren derivate |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04020599T ATE407131T1 (de) | 2000-04-08 | 2001-04-05 | Substituierte bipiperidine -zwischenverbindungen und deren derivate |
Country Status (20)
Country | Link |
---|---|
US (5) | US6525070B2 (de) |
EP (2) | EP1274701B1 (de) |
JP (1) | JP2003530393A (de) |
KR (1) | KR20030005264A (de) |
CN (2) | CN1244576C (de) |
AR (2) | AR033517A1 (de) |
AT (2) | ATE298748T1 (de) |
AU (2) | AU2001246997B2 (de) |
BR (1) | BR0109922A (de) |
CA (1) | CA2403012A1 (de) |
DE (2) | DE60111734T2 (de) |
ES (1) | ES2311772T3 (de) |
HK (1) | HK1051193A1 (de) |
IL (1) | IL151889A0 (de) |
MX (1) | MXPA02009885A (de) |
MY (1) | MY128441A (de) |
NO (1) | NO20024774L (de) |
NZ (1) | NZ521543A (de) |
SA (1) | SA01220034B1 (de) |
WO (1) | WO2001077101A1 (de) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR033517A1 (es) * | 2000-04-08 | 2003-12-26 | Astrazeneca Ab | Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos |
DK1404667T3 (da) * | 2001-07-02 | 2006-07-10 | Astrazeneca Ab | Piperidinderivater, der er anvendelige som modulatorer af chemokinreceptoraktivitet |
GB0120461D0 (en) | 2001-08-22 | 2001-10-17 | Astrazeneca Ab | Novel compounds |
AR036366A1 (es) | 2001-08-29 | 2004-09-01 | Schering Corp | Derivados de piperidina utiles como antagonistas de ccr5, composiciones farmaceuticas, el uso de dichos derivados para la fabricación de un medicamento y un kit |
GB0122503D0 (en) | 2001-09-18 | 2001-11-07 | Astrazeneca Ab | Chemical compounds |
GB0124020D0 (en) * | 2001-10-05 | 2001-11-28 | Astrazeneca Ab | Chemical compounds |
WO2003031432A1 (en) * | 2001-10-12 | 2003-04-17 | Novo Nordisk A/S | Substituted piperidines and their use for the treatment of diseases related to the histamine h3 receptor |
AU2002363236A1 (en) * | 2001-10-30 | 2003-05-12 | Millennium Pharmaceuticals, Inc. | Compounds, pharmaceutical compositions and methods of use therefor |
US6949590B2 (en) * | 2002-01-10 | 2005-09-27 | University Of Washington | Hydrogels formed by non-covalent linkages |
TW200303304A (en) * | 2002-02-18 | 2003-09-01 | Astrazeneca Ab | Chemical compounds |
US7183276B2 (en) | 2002-02-28 | 2007-02-27 | Takeda Pharmaceutical Company Limited | Azole compounds |
SE0200843D0 (sv) * | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
SE0200844D0 (sv) | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
SE0202838D0 (sv) * | 2002-09-24 | 2002-09-24 | Astrazeneca Ab | Chemical compounds |
JP4666256B2 (ja) * | 2002-12-10 | 2011-04-06 | 小野薬品工業株式会社 | 含窒素複素環化合物およびその医薬用途 |
BRPI0406778A (pt) | 2003-01-17 | 2006-01-17 | Warner Lambert Co | Antagonistas de receptores de androgênio |
US20040192738A1 (en) * | 2003-03-18 | 2004-09-30 | Aventis Pharma Deutschland Gmbh | 2-(Butyl-1-sulfonylamino)-N-[1(R)-(6-methoxypyridin-3-yl)propyl] benzamide, its use as a medicament, and pharmaceutical preparations comprising it |
SE0300850D0 (sv) * | 2003-03-25 | 2003-03-25 | Astrazeneca Ab | Chemical compounds |
SE0300957D0 (sv) | 2003-04-01 | 2003-04-01 | Astrazeneca Ab | Chemical compounds |
WO2004092136A1 (ja) * | 2003-04-18 | 2004-10-28 | Ono Pharmaceutical Co., Ltd. | 含窒素複素環化合物およびその用途 |
SE0301368D0 (sv) * | 2003-05-09 | 2003-05-09 | Astrazeneca Ab | Chemical compounds |
KR20060009390A (ko) * | 2003-06-13 | 2006-01-31 | 쉐링 악티엔게젤샤프트 | Ccr-5 길항제로서의 퀴놀릴 아미드 유도체 |
EP1638939A2 (de) * | 2003-06-24 | 2006-03-29 | Neurosearch A/S | Derivative mit aza-ring und deren verwendung als inhibitoren der wiederaufnahme von monoaminneurotransmittern |
EP1642898B1 (de) * | 2003-06-27 | 2013-03-27 | Msd K.K. | Stickstoffhaltiges, gesättigtes, heterocyclisches heteroaryloxyderivat |
US7872014B2 (en) | 2003-07-23 | 2011-01-18 | Exelixis, Inc. | Anaplastic lymphoma kinase modulators and methods of use |
GB0325956D0 (en) * | 2003-11-06 | 2003-12-10 | Addex Pharmaceuticals Sa | Novel compounds |
SE0302956D0 (sv) * | 2003-11-07 | 2003-11-07 | Astrazeneca Ab | Chemical compounds |
SE0400208D0 (sv) | 2004-02-02 | 2004-02-02 | Astrazeneca Ab | Chemical compounds |
CN1946402A (zh) * | 2004-02-05 | 2007-04-11 | 先灵公司 | 用作ccr3拮抗剂的哌啶衍生物 |
SE0400925D0 (sv) * | 2004-04-06 | 2004-04-06 | Astrazeneca Ab | Chemical compounds |
US7495012B2 (en) | 2004-04-20 | 2009-02-24 | Amgen Inc. | Arylsulfonamides and uses related thereto |
TWI396686B (zh) | 2004-05-21 | 2013-05-21 | Takeda Pharmaceutical | 環狀醯胺衍生物、以及其製品和用法 |
KR100896546B1 (ko) * | 2004-08-10 | 2009-05-07 | 노파르티스 아게 | Ccr3 억제 활성을 갖는 피페라진 유도체 |
GB0417804D0 (en) | 2004-08-10 | 2004-09-15 | Novartis Ag | Organic compounds |
GB0510143D0 (en) * | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds A1 |
KR20070091677A (ko) * | 2004-12-24 | 2007-09-11 | 아스트라제네카 아베 | Ccr2b 길항제로서의 헤테로시클릭 화합물 |
AU2006214380A1 (en) * | 2005-02-16 | 2006-08-24 | Pharmacopeia, Inc. | Pyrazinyl substituted piperazine-piperidines with CXCR3 antagonist activity |
PE20061012A1 (es) * | 2005-02-23 | 2006-10-03 | Schering Corp | Derivados piperidinil piperazina como inhibidores de receptores quiomicina |
PE20061074A1 (es) * | 2005-02-23 | 2006-11-08 | Schering Corp | Derivados de piperidinil piperidina como inhibidores de receptores de quimioquinas |
GB0510141D0 (en) * | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B3 |
TW200722419A (en) * | 2005-05-27 | 2007-06-16 | Astrazeneca Ab | Chemical compounds |
WO2006126948A1 (en) * | 2005-05-27 | 2006-11-30 | Astrazeneca Ab | Piperidines for the treatment of chemokine mediated diseases |
NZ565040A (en) | 2005-06-28 | 2010-05-28 | Sanofi Aventis | Isoquinoline derivatives as inhibitors of RHO-kinase |
CA2615650A1 (en) | 2005-07-21 | 2007-01-25 | Astrazeneca Ab | Novel piperidine derivatives |
RU2440988C2 (ru) | 2005-07-26 | 2012-01-27 | Санофи-Авентис | ПРОИЗВОДНЫЕ ЦИКЛОГЕКСИЛАМИНИЗОХИНОЛОНА В КАЧЕСТВЕ ИНГИБИТОРОВ Rho-КИНАЗЫ |
CA2615577C (en) | 2005-07-26 | 2014-09-09 | Sanofi-Aventis | Piperidinyl-substituted isoquinolone derivatives as rho-kinase inhibitors |
CN109053523B (zh) | 2005-10-07 | 2022-03-25 | 埃克塞利希斯股份有限公司 | 作为用于治疗增生性疾病的mek抑制剂的吖丁啶 |
US7576106B2 (en) * | 2005-10-11 | 2009-08-18 | Chemocentryx, Inc. | Piperidine derivatives and methods of use |
WO2007076318A2 (en) * | 2005-12-21 | 2007-07-05 | Smithkline Beecham Corporation | Camphor-derived cxcr3 antagonists |
KR101081293B1 (ko) | 2006-01-18 | 2011-11-08 | 에프. 호프만-라 로슈 아게 | 11 베타-에이치에스디1 억제제로서 티아졸 |
US20090124636A1 (en) * | 2006-04-12 | 2009-05-14 | Pfizer Inc. | Chemical compounds |
US8649933B2 (en) | 2006-11-07 | 2014-02-11 | Smartdrive Systems Inc. | Power management systems for automotive video event recorders |
US8754107B2 (en) * | 2006-11-17 | 2014-06-17 | Abbvie Inc. | Aminopyrrolidines as chemokine receptor antagonists |
CA2671982C (en) | 2006-12-14 | 2016-01-26 | Exelixis, Inc. | Methods of using mek inhibitors |
SI2102164T1 (sl) | 2006-12-27 | 2011-03-31 | Sanofi Aventis | Izokinolinski in izokinolinonski derivati, substituirani s cikloalkilaminom |
CA2673921C (en) | 2006-12-27 | 2015-10-20 | Sanofi-Aventis | New substituted isoquinoline and isoquinolinone derivatives |
AU2007338408B2 (en) | 2006-12-27 | 2012-07-26 | Sanofi-Aventis | Substituted isoquinoline and isoquinolinone derivatives |
KR101517154B1 (ko) | 2006-12-27 | 2015-04-30 | 사노피 | Rho-키나제의 억제제로서의 치환된 이소퀴놀린 및 이소퀴놀리논 유도체 |
EP2125746B1 (de) | 2006-12-27 | 2012-04-18 | Sanofi | Cycloalkylaminsubstituierte isochinolinderivate |
AU2007338407B2 (en) | 2006-12-27 | 2012-08-02 | Sanofi-Aventis | Cycloalkylamine substituted isoquinolone derivatives |
JPWO2008108309A1 (ja) * | 2007-03-02 | 2010-06-17 | 協和発酵キリン株式会社 | 縮環ピリジン誘導体 |
US20100249111A1 (en) * | 2007-04-26 | 2010-09-30 | Avalon Pharmaceuticals | Multi-ring compounds and uses thereof |
CA2691662A1 (en) * | 2007-07-02 | 2009-01-08 | F. Hoffmann-La Roche Ag | Imidazole derivatives as ccr2 receptor antagonists |
CA2700691A1 (en) | 2007-10-01 | 2009-04-09 | F. Hoffmann-La Roche Ag | New biaryl derivatives |
AU2009262516B8 (en) | 2008-06-24 | 2014-01-30 | Sanofi | 6-substituted isoquinolines and isoquinolinones |
CN102131784B (zh) | 2008-06-24 | 2014-08-27 | 赛诺菲-安万特 | 作为rho激酶抑制剂的取代的异喹啉和异喹啉酮 |
DK2303845T3 (da) | 2008-06-24 | 2013-12-16 | Sanofi Sa | Bi- og polycyklisk substitueret isoquinolin og bi- og polycykliske substituerede isoquinolinderivater som rho-kinasehæmmere |
HUP0800478A2 (en) * | 2008-07-31 | 2010-03-01 | Sanofi Aventis | Substituted pyrrolidinyl-[1,3]thiazolo[4,5-b]pyridin derivatives as ccr3 receptor ligands |
ES2775000T3 (es) | 2009-04-02 | 2020-07-23 | Merck Patent Gmbh | Derivados de piperidina y piperazina como inhibidores de autotaxina |
US8278302B2 (en) * | 2009-04-08 | 2012-10-02 | Boehringer Ingelheim International Gmbh | Substituted piperidines as CCR3 antagonists |
US8435977B2 (en) | 2009-04-22 | 2013-05-07 | Janssen Pharmaceutica, Nv | Heteroaromatic and aromatic piperazinyl azetidinyl amides as monoacylglycerol lipase inhibitors |
TW201105654A (en) | 2009-04-22 | 2011-02-16 | Janssen Pharmaceutica Nv | Azetidinyl diamides as monoacylglycerol lipase inhibitors |
WO2010129351A1 (en) | 2009-04-28 | 2010-11-11 | Schepens Eye Research Institute | Method to identify and treat age-related macular degeneration |
UY32940A (es) | 2009-10-27 | 2011-05-31 | Bayer Cropscience Ag | Amidas sustituidas con halogenoalquilo como insecticidas y acaricidas |
US8356975B2 (en) * | 2010-03-23 | 2013-01-22 | United Technologies Corporation | Gas turbine engine with non-axisymmetric surface contoured vane platform |
CA2809991A1 (en) | 2010-09-03 | 2012-03-08 | Janssen Pharmaceutica Nv | Di-azetidinyl diamide as monoacylglycerol lipase inhibitors |
JP2013537920A (ja) | 2010-09-27 | 2013-10-07 | ヤンセン ファーマシューティカ エヌ.ベー. | モノアシルグリセロールリパーゼ阻害剤としてのオキソピペラジン−アゼチジンアミド及びオキソジアゼピン−アゼチジンアミド |
BR112013009828A2 (pt) | 2010-10-22 | 2016-07-26 | Janssen Pharmaceutica Nv | diamidas de amino-pirrolidina-azetidina como inibidores de monoacilglicerol lipase |
US8513423B2 (en) | 2010-10-22 | 2013-08-20 | Janssen Pharmaceutica, Nv | Piperidin-4-yl-azetidine diamides as monoacylglycerol lipase inhibitors |
CR20200237A (es) | 2012-10-12 | 2020-07-26 | Exelixis Inc | Proceso novedoso para la elaboración de compuestos para su uso en el tratamiento del cáncer (diviisional 2015-0245) |
CA2924062C (en) * | 2013-09-10 | 2019-05-14 | Board Of Regents Of The University Of Texas System | Therapeutics targeting truncated adenomatous polyposis coli (apc) proteins |
WO2018112843A1 (en) | 2016-12-22 | 2018-06-28 | Merck Sharp & Dohme Corp. | Heteroaryl piperidine ether allosteric modulators of the m4 muscarinic acetylcholine receptor |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4505915A (en) * | 1979-05-29 | 1985-03-19 | Merck & Co., Inc. | 6-N-Heterocyclyl penicillins |
US4556660A (en) * | 1982-07-12 | 1985-12-03 | Janssen Pharmaceutica N.V. | N-(Bicyclic heterocyclyl)-4-piperidinamines |
US4634704A (en) * | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
PH23995A (en) * | 1984-01-09 | 1990-02-09 | Janssen Pharmaceutica Nv | 4((bicycle heterocyclyl)-methyl and hetero)piperidines |
US4588722A (en) * | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
US4695575A (en) * | 1984-11-13 | 1987-09-22 | Janssen Pharmaceutica, N.V. | 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines |
US5889006A (en) * | 1995-02-23 | 1999-03-30 | Schering Corporation | Muscarinic antagonists |
IL117149A0 (en) * | 1995-02-23 | 1996-06-18 | Schering Corp | Muscarinic antagonists |
US5696267A (en) * | 1995-05-02 | 1997-12-09 | Schering Corporation | Substituted oximes, hydrazones and olefins as neurokinin antagonists |
US5952349A (en) * | 1996-07-10 | 1999-09-14 | Schering Corporation | Muscarinic antagonists for treating memory loss |
HUP9904622A3 (en) | 1996-07-10 | 2001-07-30 | Schering Corp | 1,4-di-sustituted piperidines as muscarinic antagonists |
EP0821954A1 (de) * | 1996-08-01 | 1998-02-04 | Eli Lilly And Company | Verfahren zur Behandlung von geistiger Zurückgebliebenheit |
US5977138A (en) * | 1996-08-15 | 1999-11-02 | Schering Corporation | Ether muscarinic antagonists |
ES2241053T3 (es) * | 1996-08-15 | 2005-10-16 | Schering Corporation | Eteres antagonistas muscarinicos. |
CA2262818A1 (en) * | 1996-09-10 | 1998-03-19 | Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung | Modified amino acids, pharmaceuticals containing these compounds and methods for their production |
EP1003514A4 (de) | 1997-07-25 | 2000-10-11 | Merck & Co Inc | Cyclische amine modulatoren der chemokinrezeptoren |
TWI245763B (en) * | 1998-04-02 | 2005-12-21 | Janssen Pharmaceutica Nv | Biocidal benzylbiphenyl derivatives |
US6066636A (en) | 1998-06-30 | 2000-05-23 | Schering Corporation | Muscarinic antagonists |
JP3344997B2 (ja) | 1998-06-30 | 2002-11-18 | シェーリング コーポレイション | ムスカリン性アンタゴニスト |
CA2347912A1 (en) * | 1998-12-18 | 2000-06-22 | Soo S. Ko | Heterocyclic piperidines as modulators of chemokine receptor activity |
BR0010607A (pt) | 1999-05-04 | 2002-02-13 | Schering Corp | Derivados de piperidina úteis como antagonistas de ccr5 |
US6387930B1 (en) * | 1999-05-04 | 2002-05-14 | Schering Corporation | Piperidine derivatives useful as CCR5 antagonists |
US6294554B1 (en) * | 1999-09-22 | 2001-09-25 | Schering Corporation | Muscarinic antagonists |
AR033517A1 (es) * | 2000-04-08 | 2003-12-26 | Astrazeneca Ab | Derivados de piperidina, proceso para su preparacion y uso de estos derivados en la fabricacion de medicamentos |
DK1404667T3 (da) * | 2001-07-02 | 2006-07-10 | Astrazeneca Ab | Piperidinderivater, der er anvendelige som modulatorer af chemokinreceptoraktivitet |
GB0117899D0 (en) * | 2001-07-23 | 2001-09-12 | Astrazeneca Ab | Chemical compounds |
GB0120461D0 (en) * | 2001-08-22 | 2001-10-17 | Astrazeneca Ab | Novel compounds |
GB0122503D0 (en) * | 2001-09-18 | 2001-11-07 | Astrazeneca Ab | Chemical compounds |
SE0200843D0 (sv) * | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
SE0200844D0 (sv) * | 2002-03-19 | 2002-03-19 | Astrazeneca Ab | Chemical compounds |
SE0202838D0 (sv) * | 2002-09-24 | 2002-09-24 | Astrazeneca Ab | Chemical compounds |
SE0300850D0 (sv) * | 2003-03-25 | 2003-03-25 | Astrazeneca Ab | Chemical compounds |
SE0300957D0 (sv) * | 2003-04-01 | 2003-04-01 | Astrazeneca Ab | Chemical compounds |
SE0301368D0 (sv) * | 2003-05-09 | 2003-05-09 | Astrazeneca Ab | Chemical compounds |
US7517013B1 (en) * | 2008-01-31 | 2009-04-14 | Dd&G Holdings 1, Llc | Combination cooling pad for a vehicle seat and cooled, dual-configuration bag |
-
2001
- 2001-03-30 AR ARP010101549A patent/AR033517A1/es not_active Application Discontinuation
- 2001-04-05 AT AT01920053T patent/ATE298748T1/de not_active IP Right Cessation
- 2001-04-05 IL IL15188901A patent/IL151889A0/xx unknown
- 2001-04-05 BR BR0109922-1A patent/BR0109922A/pt not_active IP Right Cessation
- 2001-04-05 NZ NZ521543A patent/NZ521543A/en unknown
- 2001-04-05 JP JP2001575574A patent/JP2003530393A/ja active Pending
- 2001-04-05 KR KR1020027013425A patent/KR20030005264A/ko active IP Right Grant
- 2001-04-05 CN CNB018106838A patent/CN1244576C/zh not_active Expired - Fee Related
- 2001-04-05 EP EP01920053A patent/EP1274701B1/de not_active Expired - Lifetime
- 2001-04-05 EP EP04020599A patent/EP1493743B1/de not_active Expired - Lifetime
- 2001-04-05 ES ES04020599T patent/ES2311772T3/es not_active Expired - Lifetime
- 2001-04-05 AU AU2001246997A patent/AU2001246997B2/en not_active Ceased
- 2001-04-05 WO PCT/SE2001/000751 patent/WO2001077101A1/en active IP Right Grant
- 2001-04-05 DE DE60111734T patent/DE60111734T2/de not_active Expired - Lifetime
- 2001-04-05 DE DE60135684T patent/DE60135684D1/de not_active Expired - Lifetime
- 2001-04-05 AU AU4699701A patent/AU4699701A/xx active Pending
- 2001-04-05 MX MXPA02009885A patent/MXPA02009885A/es active IP Right Grant
- 2001-04-05 CA CA002403012A patent/CA2403012A1/en not_active Abandoned
- 2001-04-05 AT AT04020599T patent/ATE407131T1/de not_active IP Right Cessation
- 2001-04-05 CN CN2004101022451A patent/CN1660839A/zh active Pending
- 2001-04-06 US US09/827,488 patent/US6525070B2/en not_active Expired - Fee Related
- 2001-04-06 MY MYPI20011676A patent/MY128441A/en unknown
- 2001-04-07 SA SA01220034A patent/SA01220034B1/ar unknown
-
2002
- 2002-10-03 NO NO20024774A patent/NO20024774L/no not_active Application Discontinuation
-
2003
- 2003-01-13 US US10/341,027 patent/US6903115B2/en not_active Expired - Fee Related
- 2003-05-13 US US10/436,582 patent/US7238811B2/en not_active Expired - Fee Related
- 2003-05-14 HK HK03103424A patent/HK1051193A1/xx not_active IP Right Cessation
-
2004
- 2004-09-10 AR ARP040103265A patent/AR045782A2/es not_active Application Discontinuation
-
2005
- 2005-03-10 US US11/076,773 patent/US7179922B2/en not_active Expired - Fee Related
-
2007
- 2007-04-03 US US11/732,411 patent/US20070179297A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE298748T1 (de) | (1,4')-bipiperidin verbindungen | |
DE60131971D1 (de) | 1,3,8-TRIAZA-SPIROi4,5 DECAN-4-ONDERIVATIVE ALS NEUROKININREZEPTORANTAGONISTEN | |
ATE397926T1 (de) | Glukokinase beeinflussende verbindungen | |
AU4787301A (en) | 26,27-homologated-20-epi-2-alkyl-19-nor-vitamin d compounds | |
MXPA03001425A (es) | Compuestos farmaceuticos. | |
DE50107988D1 (de) | Substituierte 1,2,3,4-tetrahydrochinolin-2-carbonsäurederivate | |
DE69939378D1 (de) | Antithrombotische verbindungen | |
DE69914594D1 (de) | Aryl-annellierte azapolycyclische verbindungen | |
ATE362919T1 (de) | Lactamverbindungen | |
DE60025958D1 (de) | 14,15-beta-methylen substituierte androgene | |
NO20030868L (no) | N-(3,5-diklor-2-metoksyfenyl)-4-metoksy-3-piperazin-1-yl- benzensulfonamid | |
DE60131781D1 (de) | Kalzilytische verbindungen | |
ATE423762T1 (de) | Calcilytische verbindungen | |
ATE283629T1 (de) | Deltamethrinhaltiges, wasserdispergierbares granulat | |
DE60228478D1 (de) | Aryl-annellierte azapolyzyklische verbindungen | |
IT1318674B1 (it) | Faramaci per l'incontinenza. | |
DE50214487D1 (de) | Substituierte 1,5-diaminopentan-3-ol-verbindungen | |
AR027974A1 (es) | 1-aril-ciclopropilmetilamino-1,3,5-triazinas substituidas | |
ZA200205115B (en) | Novel cyclic compounds. | |
ES1042496Y (es) | "pilona sumible". | |
ITCS990004V0 (it) | "termocamin0 c.c.m." | |
ITSA20010003V0 (it) | "multifase 2001". | |
DE60224192D1 (de) | Antihaemorrhagische, betain-enthaltende zusammenseuzungen | |
IT1316080B1 (it) | Crogiolo. | |
IS7299A (is) | 3,4-díhýdró-1H-ísókínólóín-2-ýl-afleiður |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |