ATE298571T1 - Flüssige pharmazeutische formulierungen mit verbesserter oraler veträglichkeit - Google Patents
Flüssige pharmazeutische formulierungen mit verbesserter oraler veträglichkeitInfo
- Publication number
- ATE298571T1 ATE298571T1 AT01987156T AT01987156T ATE298571T1 AT E298571 T1 ATE298571 T1 AT E298571T1 AT 01987156 T AT01987156 T AT 01987156T AT 01987156 T AT01987156 T AT 01987156T AT E298571 T1 ATE298571 T1 AT E298571T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical formulations
- liquid pharmaceutical
- improved oral
- oral tolerability
- tolerability
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/729,406 US6391886B1 (en) | 2000-12-04 | 2000-12-04 | Oral compositions having improved consumer aesthetics |
PCT/US2001/045035 WO2002045714A1 (en) | 2000-12-04 | 2001-11-30 | Drug formulation having improved oral tolerability |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE298571T1 true ATE298571T1 (de) | 2005-07-15 |
Family
ID=24930887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01987156T ATE298571T1 (de) | 2000-12-04 | 2001-11-30 | Flüssige pharmazeutische formulierungen mit verbesserter oraler veträglichkeit |
Country Status (11)
Country | Link |
---|---|
US (1) | US6391886B1 (de) |
EP (1) | EP1339408B1 (de) |
JP (1) | JP2004515478A (de) |
CN (1) | CN100577166C (de) |
AR (1) | AR031450A1 (de) |
AT (1) | ATE298571T1 (de) |
AU (1) | AU2002239397A1 (de) |
DE (1) | DE60111769T2 (de) |
MX (1) | MXPA03004941A (de) |
PE (1) | PE20020694A1 (de) |
WO (1) | WO2002045714A1 (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030211136A1 (en) * | 1998-09-25 | 2003-11-13 | Neema Kulkarni | Fast dissolving orally consumable films containing a sweetener |
BR0207930A (pt) * | 2001-03-05 | 2004-03-02 | Ortho Mcneil Pharm Inc | Composições farmacêuticas lìquidas com sabor mascarado |
US20030060422A1 (en) | 2001-08-31 | 2003-03-27 | Balaji Venkataraman | Tannate compositions and methods of treatment |
DE10208313A1 (de) * | 2002-02-27 | 2003-09-11 | Boehringer Ingelheim Pharma | Ambroxol für die Behandlung von schmerzhaften Zuständen im Mund und Rachenraum |
US20040028622A1 (en) * | 2002-08-12 | 2004-02-12 | Michael Gurin | Multifunctional flavor systems and method of use |
KR20050061604A (ko) * | 2002-11-22 | 2005-06-22 | 피르메니히 에스아 | 염의 짠맛을 은폐시키기 위한 구강용 조성물 |
US20040142084A1 (en) * | 2003-01-21 | 2004-07-22 | Knueven Carl J. | Alkali metal bisulfates to mask aftertaste of artificial sweeteners |
US20040185093A1 (en) * | 2003-03-18 | 2004-09-23 | Szymczak Christopher E. | Compositions containing sucralose |
EP1466949A1 (de) * | 2003-04-10 | 2004-10-13 | Symrise GmbH & Co. KG | Nichttoxische Beschichtungszusammensetzung, Verwendungsverfahren und gegen die Anlagerung von Biofouling-Organismen behandelte Gegenstände |
US7632531B2 (en) * | 2003-04-11 | 2009-12-15 | International Flavors & Fragnances Inc. | Alkyldienamides exhibiting taste and sensory effect in flavor compositions |
US7361376B2 (en) * | 2003-04-11 | 2008-04-22 | International Flavors & Fragrances Inc. | Alkyldienamides exhibiting taste and sensory effect in flavor compositions |
US6884906B2 (en) * | 2003-07-01 | 2005-04-26 | International Flavors & Fragrances Inc. | Menthyl half acid ester derivatives, processes for preparing same, and uses thereof for their cooling/refreshing effect in consumable materials |
US7141686B2 (en) * | 2003-07-10 | 2006-11-28 | International Flavors & Fragrances Inc. | E2, E4, Z8-undecatrienoic acid and ester and carboxamide derivatives thereof, organoleptic uses thereof and processes for preparing same |
US8007839B2 (en) * | 2003-10-03 | 2011-08-30 | International Flavors & Fragrances | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof |
US7329767B2 (en) * | 2003-10-03 | 2008-02-12 | International Flavors & Fragrances Inc. | Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof |
US7482378B2 (en) * | 2004-05-28 | 2009-01-27 | Millenium Specialty Chemicals, Inc. | Physiological cooling compositions |
US20060034784A1 (en) * | 2004-08-12 | 2006-02-16 | The Procter & Gamble Company | Oral compositions and systems |
EP1669056A3 (de) * | 2004-08-12 | 2007-05-30 | The Procter and Gamble Company | Mundpflegemittel und System |
US7427421B2 (en) * | 2004-09-10 | 2008-09-23 | International Flavors & Fragrances Inc. | Saturated and unsaturated N-alkamides exhibiting taste and flavor enhancement effect in flavor compositions |
US7541055B2 (en) * | 2004-09-10 | 2009-06-02 | International Flavors & Fragrances Inc. | Saturated and unsaturated N-alkamides exhibiting taste and flavor enhancement effect in flavor compositions |
US20060062811A1 (en) | 2004-09-21 | 2006-03-23 | Szymczak Christopher E | Medicinal cooling emulsions |
KR20080035637A (ko) * | 2005-10-24 | 2008-04-23 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 엔,2,3-트리메틸-2-이소프로필부타미드의 국소 통증 경감조성물 및 그의 사용 방법 |
US20070178123A1 (en) * | 2006-01-27 | 2007-08-02 | Deborah Levenson | Flavor-enhancing compositions, method of manufacture, and methods of use |
US7803353B2 (en) * | 2006-03-29 | 2010-09-28 | The Procter & Gamble Company | Oral care compositions having improved consumer aesthetics and taste |
EP1958627A3 (de) * | 2007-01-04 | 2010-09-01 | Symrise GmbH & Co. KG | Verwendung bestimmter Menthyl-3-oxocarbonsäureester als physiologisch wirksame Kühlsubstanzen |
JP2009007311A (ja) * | 2007-06-29 | 2009-01-15 | Lintec Corp | ジフェンヒドラミン−アセスルファム付加物、その製造方法及び該付加物を含有する経口製剤 |
WO2011133177A1 (en) * | 2010-04-21 | 2011-10-27 | Teikoku Pharma Usa, Inc. | Local anesthetic emulsion compositions and methods of making and using the same |
KR101297354B1 (ko) * | 2011-01-13 | 2013-08-19 | 동광제약주식회사 | 안정하고 불쾌한 맛이 차폐된 덱시부프로펜을 함유한 투명한 시럽 조성물 |
AU2012236355A1 (en) * | 2011-03-31 | 2013-10-17 | Mcneil-Ppc, Inc. | Menthol liquids composition |
HRP20220112T1 (hr) | 2013-12-24 | 2022-04-15 | Virginia Commonwealth University | Upotreba oksidacijskog sulfata kolesterola (ocs) za liječenje akutne insuficijencije jetre |
AU2016238337B2 (en) * | 2015-03-26 | 2020-08-13 | Patheon Softgels Inc. | Liquisoft capsules |
JP6794758B2 (ja) * | 2015-10-21 | 2020-12-02 | 大正製薬株式会社 | 経口液体医薬組成物 |
GB2551971B (en) * | 2016-06-29 | 2020-09-16 | Syri Ltd | Taste masked liquid pharmaceutical composition of mebeverine or pharmaceutically acceptable salts thereof |
CA3032750C (en) * | 2016-09-01 | 2021-04-13 | The Procter & Gamble Company | Medication with improved taste and sensory experience |
US20210386686A1 (en) * | 2018-10-09 | 2021-12-16 | Symrise Ag | Compositions Comprising Guaifenesin and Flavour Compounds Containing an Isovanillyl Group |
CN112439077A (zh) * | 2019-08-29 | 2021-03-05 | 鲁南制药集团股份有限公司 | 一种矫味剂组合物、制备方法及其用途 |
CN112439072A (zh) * | 2019-08-29 | 2021-03-05 | 鲁南制药集团股份有限公司 | 一种掩味组合物及其制备方法、用途 |
EP4132476A1 (de) | 2020-04-10 | 2023-02-15 | The Procter & Gamble Company | Rheologische feste orale zusammensetzung |
CN111714477B (zh) * | 2020-07-23 | 2021-06-15 | 山东迅达康兽药有限公司 | 祛痰组合物及其口服液制备方法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4136163A (en) | 1971-02-04 | 1979-01-23 | Wilkinson Sword Limited | P-menthane carboxamides having a physiological cooling effect |
CA1027347A (en) | 1972-07-20 | 1978-03-07 | David G. Rowsell | Compounds having a physiological cooling effect and compositions containing them |
JPS5888334A (ja) | 1981-11-20 | 1983-05-26 | Takasago Corp | 3−l−メントキシプロパン−1、2−ジオ−ル |
US4822597A (en) | 1987-07-13 | 1989-04-18 | Warner-Lambert Company | Anesthetic-containing chewing gum compositions |
US4853212A (en) | 1987-07-13 | 1989-08-01 | Warner-Lambert Company | Reduced base content chewing gum compositions having anesthetic properties |
US5009893A (en) * | 1989-07-17 | 1991-04-23 | Warner-Lambert Company | Breath-freshening edible compositions of methol and a carboxamide |
US5196436A (en) * | 1990-10-31 | 1993-03-23 | The Procter & Gamble Company | Dextromethorphan antitussive compositions |
BR9306371A (pt) | 1992-05-18 | 1998-06-30 | Procter & Gamble | Composições refrescantes |
JPH09504293A (ja) * | 1993-10-28 | 1997-04-28 | ザ、プロクター、エンド、ギャンブル、カンパニー | マグネシウムアルミニウムシリケート及び複数の活性成分を含有した速溶解性剤形 |
US5616621A (en) | 1995-01-30 | 1997-04-01 | American Home Products Corporation | Taste masking liquids |
US5843466A (en) | 1995-08-29 | 1998-12-01 | V. Mane Fils S.A. | Coolant compositions |
US5725865A (en) | 1995-08-29 | 1998-03-10 | V. Mane Fils S.A. | Coolant compositions |
US5766622A (en) * | 1996-08-14 | 1998-06-16 | The Procter & Gamble Company | Inhibiting undesirable taste in oral compositions |
AU7916798A (en) | 1997-05-22 | 1998-12-11 | Boots Company Plc, The | Pharmaceutical compositions of flurbiprofen and burn-masking agent for treating sore throat |
JP4300652B2 (ja) * | 1998-09-21 | 2009-07-22 | 大正製薬株式会社 | 経口用固形製剤 |
US6596298B2 (en) * | 1998-09-25 | 2003-07-22 | Warner-Lambert Company | Fast dissolving orally comsumable films |
JP2000273050A (ja) | 1999-03-19 | 2000-10-03 | Kobayashi Pharmaceut Co Ltd | 苦みがマスキングされた液状製剤 |
US7067116B1 (en) * | 2000-03-23 | 2006-06-27 | Warner-Lambert Company Llc | Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1 |
-
2000
- 2000-12-04 US US09/729,406 patent/US6391886B1/en not_active Expired - Lifetime
-
2001
- 2001-11-30 EP EP01987156A patent/EP1339408B1/de not_active Expired - Lifetime
- 2001-11-30 MX MXPA03004941A patent/MXPA03004941A/es active IP Right Grant
- 2001-11-30 WO PCT/US2001/045035 patent/WO2002045714A1/en active IP Right Grant
- 2001-11-30 CN CN01820012A patent/CN100577166C/zh not_active Expired - Fee Related
- 2001-11-30 AT AT01987156T patent/ATE298571T1/de not_active IP Right Cessation
- 2001-11-30 DE DE60111769T patent/DE60111769T2/de not_active Expired - Lifetime
- 2001-11-30 JP JP2002547498A patent/JP2004515478A/ja active Pending
- 2001-11-30 AU AU2002239397A patent/AU2002239397A1/en not_active Abandoned
- 2001-12-03 PE PE2001001213A patent/PE20020694A1/es not_active Application Discontinuation
- 2001-12-03 AR ARP010105597A patent/AR031450A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
US6391886B1 (en) | 2002-05-21 |
JP2004515478A (ja) | 2004-05-27 |
AR031450A1 (es) | 2003-09-24 |
CN1575175A (zh) | 2005-02-02 |
WO2002045714A1 (en) | 2002-06-13 |
EP1339408B1 (de) | 2005-06-29 |
CN100577166C (zh) | 2010-01-06 |
MXPA03004941A (es) | 2003-09-10 |
PE20020694A1 (es) | 2002-09-25 |
AU2002239397A1 (en) | 2002-06-18 |
EP1339408A1 (de) | 2003-09-03 |
DE60111769D1 (de) | 2005-08-04 |
DE60111769T2 (de) | 2006-04-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |