ATE278706T1 - Verfahren zur konzentrierung von unlöslichen protein mittels filtration mit schwingenden membranen - Google Patents

Verfahren zur konzentrierung von unlöslichen protein mittels filtration mit schwingenden membranen

Info

Publication number
ATE278706T1
ATE278706T1 AT02704642T AT02704642T ATE278706T1 AT E278706 T1 ATE278706 T1 AT E278706T1 AT 02704642 T AT02704642 T AT 02704642T AT 02704642 T AT02704642 T AT 02704642T AT E278706 T1 ATE278706 T1 AT E278706T1
Authority
AT
Austria
Prior art keywords
insoluble protein
vibrating membranes
membranes filtration
concentrating
concentrating insoluble
Prior art date
Application number
AT02704642T
Other languages
English (en)
Inventor
Benoit Champluvier
Philippe Jean Gervais Permanne
S A Biologicals
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Application granted granted Critical
Publication of ATE278706T1 publication Critical patent/ATE278706T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/147—Microfiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/16—Feed pretreatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/16—Rotary, reciprocated or vibrated modules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/04—Specific process operations in the feed stream; Feed pretreatment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
AT02704642T 2001-01-09 2002-01-07 Verfahren zur konzentrierung von unlöslichen protein mittels filtration mit schwingenden membranen ATE278706T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0100513.1A GB0100513D0 (en) 2001-01-09 2001-01-09 Process
PCT/EP2002/000063 WO2002055539A1 (en) 2001-01-09 2002-01-07 Process to concentrate insoluble proteins by vibrating membrane filtration

Publications (1)

Publication Number Publication Date
ATE278706T1 true ATE278706T1 (de) 2004-10-15

Family

ID=9906486

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02704642T ATE278706T1 (de) 2001-01-09 2002-01-07 Verfahren zur konzentrierung von unlöslichen protein mittels filtration mit schwingenden membranen

Country Status (9)

Country Link
US (1) US6939697B2 (de)
EP (1) EP1349868B1 (de)
JP (1) JP4074519B2 (de)
AT (1) ATE278706T1 (de)
CA (1) CA2433689A1 (de)
DE (1) DE60201496T2 (de)
ES (1) ES2229091T3 (de)
GB (1) GB0100513D0 (de)
WO (1) WO2002055539A1 (de)

Families Citing this family (28)

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WO2008027861A1 (en) * 2006-08-30 2008-03-06 Ge Healthcare Bio-Sciences Corp. System and method for characterizing membranes and membrane filtration devices
CA2677023C (en) * 2007-02-22 2016-08-30 Baxter International Inc. Method of purification of hydrophobic proteins
US8158405B2 (en) * 2008-06-30 2012-04-17 General Electric Company Process for concentrating and processing fluid samples
US8546127B2 (en) * 2008-06-30 2013-10-01 General Electric Company Bacteria/RNA extraction device
DE102009010484A1 (de) * 2009-02-25 2010-08-26 Gea Westfalia Separator Gmbh Filtrationsverfahren und -vorrichtung
EP2565269B1 (de) 2010-04-30 2016-11-16 Asahi Kasei Pharma Corporation Verfahren zur herstellung von hochreinem löslichen thrombomodulin
US9475709B2 (en) 2010-08-25 2016-10-25 Lockheed Martin Corporation Perforated graphene deionization or desalination
US9028663B2 (en) 2012-03-21 2015-05-12 Lockheed Martin Corporation Molecular separation device
US20130277305A1 (en) * 2012-04-19 2013-10-24 Lockheed Martin Corporation Selectively perforated graphene membranes for compound harvest, capture and retention
US9610546B2 (en) 2014-03-12 2017-04-04 Lockheed Martin Corporation Separation membranes formed from perforated graphene and methods for use thereof
US9834809B2 (en) 2014-02-28 2017-12-05 Lockheed Martin Corporation Syringe for obtaining nano-sized materials for selective assays and related methods of use
US10653824B2 (en) 2012-05-25 2020-05-19 Lockheed Martin Corporation Two-dimensional materials and uses thereof
US9744617B2 (en) 2014-01-31 2017-08-29 Lockheed Martin Corporation Methods for perforating multi-layer graphene through ion bombardment
US10376845B2 (en) 2016-04-14 2019-08-13 Lockheed Martin Corporation Membranes with tunable selectivity
WO2014164621A1 (en) 2013-03-12 2014-10-09 Lockheed Martin Corporation Method for forming filter with uniform aperture size
US9572918B2 (en) 2013-06-21 2017-02-21 Lockheed Martin Corporation Graphene-based filter for isolating a substance from blood
CN105940479A (zh) 2014-01-31 2016-09-14 洛克希德马丁公司 使用宽离子场穿孔二维材料
CN106029596A (zh) 2014-01-31 2016-10-12 洛克希德马丁公司 采用多孔非牺牲性支撑层的二维材料形成复合结构的方法
CA2942496A1 (en) 2014-03-12 2015-09-17 Lockheed Martin Corporation Separation membranes formed from perforated graphene
CA2973472A1 (en) 2014-09-02 2016-03-10 Lockheed Martin Corporation Hemodialysis and hemofiltration membranes based upon a two-dimensional membrane material and methods employing same
AU2016303048A1 (en) 2015-08-05 2018-03-01 Lockheed Martin Corporation Perforatable sheets of graphene-based material
JP2018530499A (ja) 2015-08-06 2018-10-18 ロッキード・マーチン・コーポレーション グラフェンのナノ粒子変性及び穿孔
CA3020686A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Method for treating graphene sheets for large-scale transfer using free-float method
KR20190018410A (ko) 2016-04-14 2019-02-22 록히드 마틴 코포레이션 흐름 통로들을 갖는 2차원 막 구조들
WO2017180134A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Methods for in vivo and in vitro use of graphene and other two-dimensional materials
KR20180133430A (ko) 2016-04-14 2018-12-14 록히드 마틴 코포레이션 결함 형성 또는 힐링의 인 시츄 모니터링 및 제어를 위한 방법
WO2017180141A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Selective interfacial mitigation of graphene defects
EP3606936B1 (de) * 2017-04-03 2021-10-20 Novozymes A/S Verfahren zur rückgewinnung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900449A (en) * 1987-05-20 1990-02-13 Gelman Sciences Filtration membranes and method of making the same
US4872988A (en) * 1988-02-02 1989-10-10 Culkin Joseph B Method and device for separation of colloidal suspensions
US4952317A (en) 1989-03-10 1990-08-28 Bradley Culkin Device and method for filtering a colloidal suspension
US5468844A (en) * 1994-01-07 1995-11-21 Protose Technologies Inc. Process for the membrane-filtering of protein solutions
US5911880A (en) * 1995-12-15 1999-06-15 Research Corporation Technologies, Inc. Self-wetting membranes from engineering plastics
WO1998009717A1 (en) 1996-09-06 1998-03-12 Pall Corporation Shear separation method and system

Also Published As

Publication number Publication date
US6939697B2 (en) 2005-09-06
JP2004532183A (ja) 2004-10-21
US20040072314A1 (en) 2004-04-15
DE60201496T2 (de) 2006-03-09
WO2002055539A1 (en) 2002-07-18
EP1349868B1 (de) 2004-10-06
GB0100513D0 (en) 2001-02-21
JP4074519B2 (ja) 2008-04-09
EP1349868A1 (de) 2003-10-08
ES2229091T3 (es) 2005-04-16
CA2433689A1 (en) 2002-07-18
DE60201496D1 (de) 2004-11-11

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