ATE245192T1 - Verfahren zur herstellung von gereinigten papillomavirus proteinen - Google Patents

Verfahren zur herstellung von gereinigten papillomavirus proteinen

Info

Publication number
ATE245192T1
ATE245192T1 AT95942431T AT95942431T ATE245192T1 AT E245192 T1 ATE245192 T1 AT E245192T1 AT 95942431 T AT95942431 T AT 95942431T AT 95942431 T AT95942431 T AT 95942431T AT E245192 T1 ATE245192 T1 AT E245192T1
Authority
AT
Austria
Prior art keywords
producing purified
papillomavirus proteins
purified papillomavirus
proteins
producing
Prior art date
Application number
AT95942431T
Other languages
English (en)
Inventor
Ernest D Lehman
James C Cook Iii
Hugh A George
Kathryn J Hofmann
Kathrin U Jansen
Joseph G Joyce
Henry Z Markus
Loren D Schultz
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE245192T1 publication Critical patent/ATE245192T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20023Virus like particles [VLP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT95942431T 1994-11-14 1995-11-13 Verfahren zur herstellung von gereinigten papillomavirus proteinen ATE245192T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33936894A 1994-11-14 1994-11-14
PCT/US1995/015027 WO1996015247A1 (en) 1994-11-14 1995-11-13 Purified papillomavirus proteins

Publications (1)

Publication Number Publication Date
ATE245192T1 true ATE245192T1 (de) 2003-08-15

Family

ID=23328696

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95942431T ATE245192T1 (de) 1994-11-14 1995-11-13 Verfahren zur herstellung von gereinigten papillomavirus proteinen

Country Status (23)

Country Link
EP (1) EP0789767B1 (de)
JP (1) JPH11500002A (de)
KR (1) KR987000420A (de)
CN (1) CN1173203A (de)
AR (1) AR004464A1 (de)
AT (1) ATE245192T1 (de)
AU (1) AU708737B2 (de)
BR (1) BR9510520A (de)
CZ (1) CZ145297A3 (de)
DE (1) DE69531308T2 (de)
DK (1) DK0789767T3 (de)
ES (1) ES2201129T3 (de)
FI (1) FI972030A0 (de)
HR (1) HRP950557A2 (de)
HU (1) HUT77559A (de)
MX (1) MX9703570A (de)
NZ (1) NZ298224A (de)
PT (1) PT789767E (de)
RU (1) RU2161651C2 (de)
SK (1) SK281878B6 (de)
UA (1) UA35639C2 (de)
WO (1) WO1996015247A1 (de)
YU (1) YU71195A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6153201A (en) * 1993-03-09 2000-11-28 University Of Rochester Oral immunization with papillomavirus virus-like particles
JPH10506014A (ja) * 1994-09-22 1998-06-16 メルク エンド カンパニー インコーポレーテッド ヒトパピローマウイルス6a型をコードするDNA
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
NZ500028A (en) * 1997-04-08 2001-08-31 Merck & Co Inc Stabilized human papillomavirus formulations also containing a salt and a nonionic surfactant
ATE324436T1 (de) * 1998-08-14 2006-05-15 Merck & Co Inc Verfahren zur reinigung von menschlichen, dem papillomavirus ähnlichen partikeln.
AUPP765398A0 (en) 1998-12-11 1999-01-14 University Of Queensland, The Treatment of papillomavirus infections
PT1150712E (pt) 1999-02-05 2008-12-22 Merck & Co Inc Formulações para a vacina do vírus do papiloma humano
GB0206360D0 (en) 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
ES2323454T5 (es) 2002-04-30 2012-11-14 Oncolytics Biotech Inc. Procedimiento mejorado de purificación de virus
MY140664A (en) 2003-09-29 2010-01-15 Merck Sharp & Dohme Optimized expression of hpv 45 l1 in yeast
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
SG10201701988TA (en) 2007-03-14 2017-04-27 Ligocyte Pharmaceuticals Inc Virus like particle purification
PL2444103T3 (pl) * 2009-06-19 2018-05-30 Eyegene Inc. Szczepionka przeciwko rakowi szyjki macicy
JOP20130186B1 (ar) 2012-06-22 2021-08-17 Takeda Vaccines Montana Inc تنقية الجزيئات الشبيهة بالفيروسات
CN103936840B (zh) * 2013-01-18 2019-04-09 北京康乐卫士生物技术股份有限公司 重组的人***瘤病毒33型l1蛋白及其用途
CN113278064B (zh) * 2021-07-20 2021-11-02 山东信得科技股份有限公司 一种用于胚毒类抗原净化处理的方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122007000019I1 (de) * 1991-07-19 2007-07-26 Univ Queensland Impfstoffen gegen Papillomavirus
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
CA2157932C (en) * 1993-03-09 2011-10-11 Robert C. Rose Production of human papillomavirus capsid protein and virus-like particles
BR9507657A (pt) * 1994-05-16 1997-09-09 Merck & Co Inc Proteina isolada e purificada de papilomavirus recombinante capsideos particulas semelhantes a virus processos a virus processos para produzir a proteina para tratar ou prevenir a infecçao por papilomavirus para produzir uma proteina de capsideo de papilomavirus recombinante montada em um capsideo ou particula semelhante a virus e para induzir uma resposta imune em um animal vertebrado composiçoes farmacêuticas kit para a detecçao de papilomavirus ou anticorpos para papilomavirus e sistema sinte

Also Published As

Publication number Publication date
UA35639C2 (uk) 2001-04-16
PT789767E (pt) 2003-11-28
HRP950557A2 (en) 1997-08-31
YU71195A (sh) 1999-06-15
AU708737B2 (en) 1999-08-12
DK0789767T3 (da) 2003-10-20
SK281878B6 (sk) 2001-08-06
BR9510520A (pt) 1998-07-14
KR987000420A (ko) 1998-03-30
ES2201129T3 (es) 2004-03-16
MX9703570A (es) 1997-08-30
HUT77559A (hu) 1998-06-29
NZ298224A (en) 1999-05-28
RU2161651C2 (ru) 2001-01-10
AR004464A1 (es) 1998-12-16
SK59497A3 (en) 1998-03-04
JPH11500002A (ja) 1999-01-06
DE69531308T2 (de) 2004-04-15
DE69531308D1 (de) 2003-08-21
EP0789767B1 (de) 2003-07-16
EP0789767A1 (de) 1997-08-20
AU4365896A (en) 1996-06-06
CN1173203A (zh) 1998-02-11
CZ145297A3 (en) 1997-10-15
FI972030A (fi) 1997-05-13
WO1996015247A1 (en) 1996-05-23
FI972030A0 (fi) 1997-05-13

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