ATE278391T1 - Verfahren zur herstellung kristalliner partikel - Google Patents
Verfahren zur herstellung kristalliner partikelInfo
- Publication number
- ATE278391T1 ATE278391T1 AT99963730T AT99963730T ATE278391T1 AT E278391 T1 ATE278391 T1 AT E278391T1 AT 99963730 T AT99963730 T AT 99963730T AT 99963730 T AT99963730 T AT 99963730T AT E278391 T1 ATE278391 T1 AT E278391T1
- Authority
- AT
- Austria
- Prior art keywords
- solvent
- crystalline particles
- substance
- treatment
- water
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
- B01D11/0411—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solvent and as anti-solvent for the solute, e.g. formation of particles from solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9804001A SE9804001D0 (sv) | 1998-11-23 | 1998-11-23 | New process |
PCT/SE1999/002153 WO2000030613A1 (en) | 1998-11-23 | 1999-11-22 | New process |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE278391T1 true ATE278391T1 (de) | 2004-10-15 |
Family
ID=20413378
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99963730T ATE278391T1 (de) | 1998-11-23 | 1999-11-22 | Verfahren zur herstellung kristalliner partikel |
Country Status (12)
Country | Link |
---|---|
US (1) | US6461642B1 (de) |
EP (1) | EP1133284B2 (de) |
JP (1) | JP4616993B2 (de) |
AT (1) | ATE278391T1 (de) |
AU (1) | AU767767B2 (de) |
CA (1) | CA2348084C (de) |
DE (1) | DE69920946T3 (de) |
DK (1) | DK1133284T4 (de) |
ES (1) | ES2228149T5 (de) |
PT (1) | PT1133284E (de) |
SE (1) | SE9804001D0 (de) |
WO (1) | WO2000030613A1 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH694686A5 (it) | 2000-03-04 | 2005-06-15 | Eco2 Sa | Prodotto di micronizzazione di sostanze farmaceutiche. |
GB0016040D0 (en) * | 2000-06-29 | 2000-08-23 | Glaxo Group Ltd | Novel process for preparing crystalline particles |
ES2170008B1 (es) * | 2000-08-25 | 2003-05-01 | Soc Es Carburos Metalicos Sa | Procedimiento para la precipitacion de particulas solidas finamente divididas. |
FR2815540B1 (fr) * | 2000-10-19 | 2005-06-10 | Separex Sa | Procede de fabrication de tres fines particules constituees d'un principe insere dans une molecule hote |
GB0027357D0 (en) | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
GB0102075D0 (en) * | 2001-01-26 | 2001-03-14 | Astrazeneca Ab | Process |
US20030055026A1 (en) | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
CA2461349C (en) | 2001-09-26 | 2011-11-29 | Baxter International Inc. | Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal |
RS29104A (en) * | 2001-10-10 | 2006-12-15 | Boehringer Ingelheim Pharmaceuticals Inc. | Powder processing with pressurized gaseous fluids |
FR2830760B1 (fr) * | 2001-10-12 | 2004-06-04 | Pf Medicament | Procede de preparation d'un compose d'interaction de substances actives avec un support poreux par fluide supercritique |
EP1572156A1 (de) * | 2002-12-19 | 2005-09-14 | Baxter International Inc. | Verfahren zurherstellung von pharmazeutischen kombiformulierungen unter verwendung vonüberkritischen flüssigkeiten |
KR20060015587A (ko) | 2003-05-08 | 2006-02-17 | 넥타 쎄라퓨틱스 유케이 리미티드 | 미립물 |
EP1654001A2 (de) * | 2003-08-05 | 2006-05-10 | Boehringer Ingelheim International GmbH | Medikamente zur inhalation mit steroiden und einem betamimetikum |
ES2314465T5 (es) * | 2003-11-19 | 2012-10-29 | Natex Prozesstechnologie Gesmbh | Un procedimiento y proceso para controlar los perfiles de temperatura, presión y densidad en procesos con fluidos densos y aparato asociado |
EP1904219A4 (de) | 2005-07-15 | 2011-07-27 | Map Pharmaceuticals Inc | Teilchenbildungsverfahren |
EP1782839A1 (de) | 2005-11-03 | 2007-05-09 | Genetic S.p.A. | Verfahren zur Sterilisation von Glucocorticosteroiden mit überkritischem CO2 |
JP2010500356A (ja) * | 2006-08-09 | 2010-01-07 | グラクソ グループ リミテッド | ラクトースの製造方法 |
JP5825757B2 (ja) | 2007-02-11 | 2015-12-02 | マップ・ファーマシューティカルズ・インコーポレイテッド | 副作用プロファイルを最小限にしながら片頭痛の迅速な緩和を可能にするdheの治療上の投与方法 |
US8426467B2 (en) | 2007-05-22 | 2013-04-23 | Baxter International Inc. | Colored esmolol concentrate |
US8722736B2 (en) | 2007-05-22 | 2014-05-13 | Baxter International Inc. | Multi-dose concentrate esmolol with benzyl alcohol |
WO2009047935A1 (ja) * | 2007-10-12 | 2009-04-16 | Ono Pharmaceutical Co., Ltd. | 微粒子 |
JP5307382B2 (ja) * | 2007-11-14 | 2013-10-02 | 日機装株式会社 | 微粒子化方法 |
PL2229233T3 (pl) * | 2007-12-07 | 2020-03-31 | Xspray Pharma Ab (Publ) | Sposób wytwarzania cząstek |
DE102008053618A1 (de) * | 2008-10-29 | 2010-07-01 | Karlsruher Institut für Technologie | Verfahren zur Ausfällung von Salzen |
ES2342140B1 (es) * | 2008-12-30 | 2011-05-17 | Consejo Superior Investigacion | Procedimiento para la obtencion de micro- o nanoparticulas solidas |
US20100294986A1 (en) * | 2009-05-19 | 2010-11-25 | Massachusetts Institute Of Technology | Supercritical fluid facilitated particle formation in microfluidic systems |
US20100298602A1 (en) * | 2009-05-19 | 2010-11-25 | Massachusetts Institute Of Technology | Systems and methods for microfluidic crystallization |
CA2767773C (en) | 2011-02-11 | 2015-11-24 | Grain Processing Corporation | Composition comprising a salt and a crystallization interrupter |
CN102327186A (zh) * | 2011-09-30 | 2012-01-25 | 四川大学 | 一种采用超临界co2流体技术制备水溶性药物缓释微粒的方法 |
GB201402556D0 (en) | 2014-02-13 | 2014-04-02 | Crystec Ltd | Improvements relating to inhalable particles |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3744329A1 (de) * | 1987-12-28 | 1989-07-06 | Schwarz Pharma Gmbh | Verfahren zur herstellung einer mindestens einen wirkstoff und einen traeger umfassenden zubereitung |
SE9302777D0 (sv) | 1993-08-27 | 1993-08-27 | Astra Ab | Process for conditioning substances |
US6063910A (en) † | 1991-11-14 | 2000-05-16 | The Trustees Of Princeton University | Preparation of protein microparticles by supercritical fluid precipitation |
US5639441A (en) * | 1992-03-06 | 1997-06-17 | Board Of Regents Of University Of Colorado | Methods for fine particle formation |
US5301664A (en) * | 1992-03-06 | 1994-04-12 | Sievers Robert E | Methods and apparatus for drug delivery using supercritical solutions |
WO1994008599A1 (en) * | 1992-10-14 | 1994-04-28 | The Regents Of The University Of Colorado | Ion-pairing of drugs for improved efficacy and delivery |
GB9313650D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
GB9313642D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
GB9413202D0 (en) † | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
SE9501384D0 (sv) * | 1995-04-13 | 1995-04-13 | Astra Ab | Process for the preparation of respirable particles |
US6126919A (en) * | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
GB9703673D0 (en) † | 1997-02-21 | 1997-04-09 | Bradford Particle Design Ltd | Method and apparatus for the formation of particles |
WO1998041193A1 (en) | 1997-03-20 | 1998-09-24 | Schering Corporation | Preparation of powder agglomerates |
-
1998
- 1998-11-23 SE SE9804001A patent/SE9804001D0/xx unknown
-
1999
- 1999-11-22 US US09/486,689 patent/US6461642B1/en not_active Expired - Fee Related
- 1999-11-22 DK DK99963730T patent/DK1133284T4/da active
- 1999-11-22 AT AT99963730T patent/ATE278391T1/de active
- 1999-11-22 PT PT99963730T patent/PT1133284E/pt unknown
- 1999-11-22 WO PCT/SE1999/002153 patent/WO2000030613A1/en active IP Right Grant
- 1999-11-22 EP EP99963730A patent/EP1133284B2/de not_active Expired - Lifetime
- 1999-11-22 ES ES99963730T patent/ES2228149T5/es not_active Expired - Lifetime
- 1999-11-22 AU AU20103/00A patent/AU767767B2/en not_active Ceased
- 1999-11-22 DE DE69920946T patent/DE69920946T3/de not_active Expired - Lifetime
- 1999-11-22 CA CA002348084A patent/CA2348084C/en not_active Expired - Fee Related
- 1999-11-22 JP JP2000583497A patent/JP4616993B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK1133284T4 (da) | 2008-11-10 |
DE69920946D1 (de) | 2004-11-11 |
ES2228149T3 (es) | 2005-04-01 |
DE69920946T3 (de) | 2009-02-26 |
CA2348084C (en) | 2009-01-06 |
JP4616993B2 (ja) | 2011-01-19 |
EP1133284B2 (de) | 2008-08-06 |
AU2010300A (en) | 2000-06-13 |
DK1133284T3 (da) | 2005-02-28 |
US6461642B1 (en) | 2002-10-08 |
CA2348084A1 (en) | 2000-06-02 |
PT1133284E (pt) | 2005-01-31 |
EP1133284A1 (de) | 2001-09-19 |
ES2228149T5 (es) | 2008-12-16 |
DE69920946T2 (de) | 2005-08-25 |
SE9804001D0 (sv) | 1998-11-23 |
EP1133284B1 (de) | 2004-10-06 |
JP2002530318A (ja) | 2002-09-17 |
AU767767B2 (en) | 2003-11-20 |
WO2000030613A1 (en) | 2000-06-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE278391T1 (de) | Verfahren zur herstellung kristalliner partikel | |
EE200100275A (et) | Kristalsesse olekusse konverteeritud amorfse ja/või metastabiilse kristalse piirkonnaga osakeste valmistamismeetod | |
DE69124357D1 (de) | Protein Nanomatrizen und Verfahren zur Herstellung | |
ATE168556T1 (de) | Stabile budesonid-lösungen, verfahren zu deren herstellung sowie verwendung dieser lösungen als klistierzubereitungen und pharmazeutische schäume | |
ATE430368T1 (de) | Verfahren und vorrichtung zur erzeugung von 18f- fluorid | |
ATE198982T1 (de) | Verfahren zur herstellung von festen pharmazeutischen dosierungsformen hydrophobischen substanzen | |
NO20055817L (no) | Apparat og fremgangsmate for behandling av injeksjonsfluid. | |
DE59500808D1 (de) | Verfahren zur herstellung von partikeln bzw. pulvern | |
IS2667B (is) | Lyfjablanda sem inniheldur andrógen | |
DE60028209D1 (de) | Verfahren und apparat zur herstellung von extrakten und ölen aus pflanzen und anderen stoffen | |
FI972093A0 (fi) | Jäteveden käsittelymenetelmä ja -laitos | |
ATE200024T1 (de) | Verfahren zur herstellung von medizinischem kaugummi mit einem guten geschmack, enthaltend eine einschlussverbindung | |
ATE334682T1 (de) | Verfahren zur herstellung von den trans-4-n- butylcyclohexanoicsaüre- und undecanoicsaüreestern von (7-alpha,11-beta)- dimethyl-17 beta -hydroxy-4-estren-3-one und deren medizynische anwendung | |
DE69839622D1 (de) | Verfahren zur Herstellung eines künstlichen Organs, Hohlfasermembran, und Hohlfaserdialysator | |
JPS619857B2 (de) | ||
DE59503394D1 (de) | Verfahren zur Herstellung von Liposomen bzw. Proliposomen | |
FI971202A0 (fi) | Levobupivakaiinin ja sen analogien valmistuksessa käytettäviä menetelmiä rasemisoinnin ja asymmetrisen muuntamisen tekemiseksi | |
DE60105528D1 (de) | Verfahren zur Herstellung von porösen Polyimid durch Extraktion von Substanzen niedrigen Molekulargewichts mittels superkritischem Kohlendioxid | |
DE69021405T2 (de) | System zur gesteuerten Freisetzung von Wirkstoffen sowie Verfahren zu dessen Herstellung. | |
DE50209881D1 (de) | Herstellung von dialysekonzentrat aus einer hochverdichteten konzentratvorstufe und vorrichtung zur anwendung am dialyseplatz. | |
ES2155746B1 (es) | Procedimiento y aparato para la produccion de carbon activo. | |
EP0537429B1 (de) | Modifizierte Huminate, Verfahren zu ihrer Herstellung und Verwendung | |
ATE181826T1 (de) | Wässriges liposomensystem sowie verfahren zur herstellung eines derartigen liposomensystems | |
HUP0103356A2 (hu) | Eljárás és berendezés kénsavgőz eltávolítására | |
ATE222887T1 (de) | Verfahren zur herstellung von inorganischen salzen von optisch aktiven phenylglycin-derivaten |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1133284 Country of ref document: EP |
|
UEP | Publication of translation of european patent specification |
Ref document number: 1133284 Country of ref document: EP |