ATE275630T1 - Fas ligand ähnliches protein, seine herstellung und verwendung - Google Patents

Fas ligand ähnliches protein, seine herstellung und verwendung

Info

Publication number
ATE275630T1
ATE275630T1 AT97930820T AT97930820T ATE275630T1 AT E275630 T1 ATE275630 T1 AT E275630T1 AT 97930820 T AT97930820 T AT 97930820T AT 97930820 T AT97930820 T AT 97930820T AT E275630 T1 ATE275630 T1 AT E275630T1
Authority
AT
Austria
Prior art keywords
protein
salt
partial peptide
fas ligand
antibody
Prior art date
Application number
AT97930820T
Other languages
English (en)
Inventor
Kazunori Nishi
Yukiko Hikichi
Yasushi Shintani
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE275630T1 publication Critical patent/ATE275630T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT97930820T 1996-07-19 1997-07-17 Fas ligand ähnliches protein, seine herstellung und verwendung ATE275630T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP19120496 1996-07-19
JP21169596 1996-08-09
JP1933097 1997-01-31
PCT/JP1997/002480 WO1998003648A1 (en) 1996-07-19 1997-07-17 Fas ligand-like protein, its production and use

Publications (1)

Publication Number Publication Date
ATE275630T1 true ATE275630T1 (de) 2004-09-15

Family

ID=27282588

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97930820T ATE275630T1 (de) 1996-07-19 1997-07-17 Fas ligand ähnliches protein, seine herstellung und verwendung

Country Status (7)

Country Link
US (2) US6235878B1 (de)
EP (1) EP0922099B1 (de)
AT (1) ATE275630T1 (de)
AU (1) AU3461797A (de)
CA (1) CA2260767A1 (de)
DE (1) DE69730607T2 (de)
WO (1) WO1998003648A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015665A (en) * 1995-02-13 2000-01-18 The Regents Of The University Of Michigan Method and composition for regulating apoptosis
US7097972B1 (en) 1995-02-13 2006-08-29 Regents Of The University Of Michigan Method and composition for regulating apoptosis
US7807783B1 (en) 1995-04-03 2010-10-05 The Regents Of The University Of Michigan Methods and compositions for regulating FAS-associated apoptosis
US6747138B1 (en) 1995-04-03 2004-06-08 Regents Of The University Of Michigan Methods and compositions for regulating Fas-associated apoptosis
EP0904278A4 (de) * 1996-03-22 1999-09-15 Human Genome Sciences Inc Apoptose-induzierendes molekül ii
US6479254B2 (en) * 1996-03-22 2002-11-12 Human Genome Sciences, Inc. Apoptosis inducing molecule II
US7964190B2 (en) 1996-03-22 2011-06-21 Human Genome Sciences, Inc. Methods and compositions for decreasing T-cell activity
US6495520B2 (en) 1996-03-22 2002-12-17 Human Genome Sciences, Inc. Apoptosis Inducing Molecule II and methods of use
US6635743B1 (en) 1996-03-22 2003-10-21 Human Genome Sciences, Inc. Apoptosis inducing molecule II and methods of use
DE69730607T2 (de) * 1996-07-19 2005-01-27 Takeda Chemical Industries, Ltd. Fas ligand ähnliches protein, seine herstellung und verwendung
US7118742B2 (en) 1997-07-07 2006-10-10 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
US6998108B1 (en) 1997-07-07 2006-02-14 La Jolla Institute For Allergy And Immunology Antibodies to p30 polypeptides and methods making and using same
US6140467A (en) * 1997-07-07 2000-10-31 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
US6346388B1 (en) 1997-08-13 2002-02-12 Smithkline Beecham Corporation Method of identifying agonist and antagonists for tumor necrosis related receptors TR1 and TR2
JP2002504333A (ja) * 1998-02-20 2002-02-12 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド アポトーシス誘導分子ｉｉおよび使用方法
WO2000024427A1 (fr) * 1998-10-28 2000-05-04 St. Marianna University School Of Medicine Remedes contre les rhumatismes contenant un gene fadd en qualite d'ingredient actif
WO2000053223A1 (en) * 1999-03-11 2000-09-14 Human Genome Sciences, Inc. Apoptosis inducing molecule ii and methods of use
EP1179347A4 (de) * 1999-05-21 2002-06-26 Takeda Chemical Industries Ltd Kontrollsubstanzen für die leberfunktion
WO2001079496A2 (en) * 2000-03-13 2001-10-25 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
WO2001075095A1 (fr) * 2000-03-30 2001-10-11 Takeda Chemical Industries, Ltd. Procede de production de proteine de recombinaison
DK1674575T3 (da) * 2000-04-12 2010-11-29 Jolla Inst Allergy Immunolog Ligand for Herpes simplex-indgangsmediator og fremgangsmåder til anvendelse
WO2002066049A1 (fr) * 2001-02-23 2002-08-29 Takeda Chemical Industries, Ltd. Agents pour changement plasmique
EP1364653A4 (de) * 2001-02-23 2005-01-26 Takeda Pharmaceutical Casoase-3-hemmer
US20030078228A1 (en) * 2001-09-24 2003-04-24 Taylor Doris A. Fas Ligand
US7273707B2 (en) * 2002-02-08 2007-09-25 Wyeth Method of identifying a modulator of a LTβR complex signaling pathway
CA2481401A1 (en) * 2002-04-15 2003-10-30 Human Genome Sciences, Inc. Antibodies that specifically bind to tl5
EP2484696B1 (de) * 2006-08-28 2017-08-16 Kyowa Hakko Kirin Co., Ltd. Antagonistische hLIGHT-spezifische menschliche monoklonale Antikörper
EP2086575A2 (de) * 2006-10-25 2009-08-12 La Jolla Institute For Allergy And Immunology Lichtvermittelte antizellproliferationzusammensetzungen und verfahren
MX2009006315A (es) 2006-12-12 2009-10-13 Takeda Pharmaceutical Compuesto heterociclico fusionado.
US20090093429A1 (en) * 2007-02-08 2009-04-09 Yang-Xin Fu Combination therapy for treating cancer
US20090233937A1 (en) 2008-03-12 2009-09-17 Takeda Pharmaceutical Company Limited Fused heterocyclic compound
WO2010051502A2 (en) 2008-10-31 2010-05-06 Biogen Idec Ma Inc. Light targeting molecules and uses thereof
RU2686323C2 (ru) 2013-03-13 2019-04-25 Форма Терапьютикс, Инк. Новые соединения и композиции для ингибирования fasn
TWI767148B (zh) 2018-10-10 2022-06-11 美商弗瑪治療公司 抑制脂肪酸合成酶(fasn)
WO2020092395A1 (en) 2018-10-29 2020-05-07 Forma Therapeutics, Inc. SOLID FORMS OF (4-(2-FLUORO-4-(1-METHYL-1 H-BENZO[d]IMIDAZOL-5-YL)BENZOYL) PIPERAZIN-1-YL)(1-HYDROXYCYCLOPROPYL)METHANONE

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08127594A (ja) 1993-11-10 1996-05-21 Mochida Pharmaceut Co Ltd Ｆａｓ抗原に結合する新規蛋白質およびそれをコードするＤＮＡ
US5663070A (en) 1993-11-15 1997-09-02 Lxr Biotechnology Inc. Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM
NZ279108A (en) * 1994-01-07 1997-06-24 Immunex Corp Human fas (tgf/ngf receptor) ligand proteins coding sequences and production
US5759536A (en) * 1994-05-27 1998-06-02 University Technology Corporation Use of fas ligand to supress T-lymphocyte-mediated immune responses
CN1214050A (zh) 1996-03-14 1999-04-14 人体基因组科学有限公司 人肿瘤坏死因子δ和ε
AU5711196A (en) 1996-03-14 1997-10-01 Human Genome Sciences, Inc. Apoptosis inducing molecule i
EP0904278A4 (de) 1996-03-22 1999-09-15 Human Genome Sciences Inc Apoptose-induzierendes molekül ii
DE69730607T2 (de) * 1996-07-19 2005-01-27 Takeda Chemical Industries, Ltd. Fas ligand ähnliches protein, seine herstellung und verwendung

Also Published As

Publication number Publication date
US6235878B1 (en) 2001-05-22
AU3461797A (en) 1998-02-10
DE69730607T2 (de) 2005-01-27
EP0922099A1 (de) 1999-06-16
DE69730607D1 (de) 2004-10-14
WO1998003648A1 (en) 1998-01-29
CA2260767A1 (en) 1998-01-29
US6590090B1 (en) 2003-07-08
EP0922099B1 (de) 2004-09-08

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