ATE269337T1 - Trizyclische delta3-pyridine als arzneimittel - Google Patents

Trizyclische delta3-pyridine als arzneimittel

Info

Publication number
ATE269337T1
ATE269337T1 AT99950628T AT99950628T ATE269337T1 AT E269337 T1 ATE269337 T1 AT E269337T1 AT 99950628 T AT99950628 T AT 99950628T AT 99950628 T AT99950628 T AT 99950628T AT E269337 T1 ATE269337 T1 AT E269337T1
Authority
AT
Austria
Prior art keywords
trizyclic
delta3
pyridines
medicinal products
medicinal
Prior art date
Application number
AT99950628T
Other languages
English (en)
Inventor
Ludo Edmond Josephine Kennis
Josephus Carolus Mertens
Mirielle Braeken
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE269337T1 publication Critical patent/ATE269337T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT99950628T 1998-10-06 1999-10-01 Trizyclische delta3-pyridine als arzneimittel ATE269337T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98203371 1998-10-06
PCT/EP1999/007420 WO2000020423A1 (en) 1998-10-06 1999-10-01 Tricyclic δ3-piperidines as pharmaceuticals

Publications (1)

Publication Number Publication Date
ATE269337T1 true ATE269337T1 (de) 2004-07-15

Family

ID=8234192

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99950628T ATE269337T1 (de) 1998-10-06 1999-10-01 Trizyclische delta3-pyridine als arzneimittel

Country Status (28)

Country Link
US (1) US6352999B1 (de)
EP (1) EP1119570B1 (de)
JP (1) JP4590102B2 (de)
KR (1) KR20010071844A (de)
CN (1) CN1131868C (de)
AR (1) AR023679A1 (de)
AT (1) ATE269337T1 (de)
AU (1) AU759199B2 (de)
BG (1) BG64871B1 (de)
BR (1) BR9913108A (de)
CA (1) CA2346082C (de)
CZ (1) CZ20011105A3 (de)
DE (1) DE69918148T2 (de)
EE (1) EE04680B1 (de)
ES (1) ES2222735T3 (de)
HK (1) HK1038009A1 (de)
HU (1) HUP0103749A3 (de)
ID (1) ID28451A (de)
IL (2) IL142444A0 (de)
NO (1) NO20011402D0 (de)
NZ (1) NZ510116A (de)
PL (1) PL347179A1 (de)
RU (1) RU2226194C2 (de)
SK (1) SK285386B6 (de)
TR (1) TR200100953T2 (de)
TW (1) TWI244485B (de)
UA (1) UA70961C2 (de)
WO (1) WO2000020423A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA69420C2 (uk) * 1998-10-06 2004-09-15 Янссен Фармацевтика Н.В. ТРИЦИКЛІЧНІ <font face="Symbol">D3</font>-ПІПЕРИДИНИ ЯК <font face="Symbol">a<sub></font>2</sub>-АНТАГОНІСТИ
MXPA04000036A (es) * 2001-07-05 2004-05-21 Upjohn Co Benzofuranos sustituidos con (hetero) arilo como ligandos 5-ht.
JP2005521728A (ja) * 2002-04-03 2005-07-21 オリオン コーポレーション CNS関連疾患のためのα2−アドレナリン受容体アンタゴニストの使用
KR20060135023A (ko) 2004-04-12 2006-12-28 다이쇼 세이야꾸 가부시끼가이샤 환상 아민 화합물
MX2007009783A (es) 2005-02-17 2007-08-22 Wyeth Corp Derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilfusionados.
DE102005038947A1 (de) * 2005-05-18 2006-11-30 Grünenthal GmbH Substituierte Benzo[d]isoxazol-3-yl-amin-Verbindungen und deren Verwendung in Arzneimitteln
CN105636946B (zh) * 2013-07-25 2017-12-19 东亚St 株式会社 制备苯甲酰胺衍生物的方法、用于制备苯甲酰胺的新型中间体以及制备新型中间体的方法
CN103755715B (zh) * 2013-12-26 2015-12-09 武汉理工大学 苯并呋喃并[2,3-c]吡啶化合物及其合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3522959A1 (de) 1985-06-27 1987-01-08 Merck Patent Gmbh Indolderivate
US4673680A (en) * 1985-09-18 1987-06-16 Pendleton Robert G α2 -adrenergic receptor antagonists as modifiers of gastrointestinal motility
EP0339959A3 (de) * 1988-04-27 1991-03-20 Glaxo Group Limited Laktam-Derivate
US5100891A (en) * 1991-01-18 1992-03-31 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds
AU735764B2 (en) * 1996-12-06 2001-07-12 Abbott Laboratories Benzopyranopyrrole and benzopyranopyridine alpha-1 adrenergic compounds
UA52681C2 (uk) 1997-04-08 2003-01-15 Янссен Фармацевтика Н.В. Похідні 1,2,3,4-тетрагідро-бензофуро[3,2,-c]піридину, спосіб їх одержання та фармацевтична композиція на їх основі
UA69420C2 (uk) * 1998-10-06 2004-09-15 Янссен Фармацевтика Н.В. ТРИЦИКЛІЧНІ <font face="Symbol">D3</font>-ПІПЕРИДИНИ ЯК <font face="Symbol">a<sub></font>2</sub>-АНТАГОНІСТИ

Also Published As

Publication number Publication date
CA2346082C (en) 2010-02-16
BG64871B1 (bg) 2006-07-31
BG105334A (en) 2001-11-30
UA70961C2 (uk) 2004-11-15
TR200100953T2 (tr) 2001-09-21
TWI244485B (en) 2005-12-01
EE04680B1 (et) 2006-08-15
JP4590102B2 (ja) 2010-12-01
CN1321158A (zh) 2001-11-07
AU759199B2 (en) 2003-04-10
DE69918148T2 (de) 2005-07-28
DE69918148D1 (de) 2004-07-22
CZ20011105A3 (cs) 2001-12-12
EE200100210A (et) 2002-06-17
NO20011402L (no) 2001-03-20
US6352999B1 (en) 2002-03-05
HUP0103749A2 (hu) 2002-02-28
JP2002526547A (ja) 2002-08-20
ID28451A (id) 2001-05-24
AU6334299A (en) 2000-04-26
NO20011402D0 (no) 2001-03-20
PL347179A1 (en) 2002-03-25
SK285386B6 (sk) 2006-12-07
NZ510116A (en) 2002-10-25
SK4332001A3 (en) 2001-12-03
HK1038009A1 (en) 2002-03-01
CA2346082A1 (en) 2000-04-13
ES2222735T3 (es) 2005-02-01
EP1119570A1 (de) 2001-08-01
BR9913108A (pt) 2001-05-08
HUP0103749A3 (en) 2003-03-28
RU2226194C2 (ru) 2004-03-27
CN1131868C (zh) 2003-12-24
AR023679A1 (es) 2002-09-04
IL142444A (en) 2008-03-20
EP1119570B1 (de) 2004-06-16
IL142444A0 (en) 2002-03-10
KR20010071844A (ko) 2001-07-31
WO2000020423A1 (en) 2000-04-13

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties