ATE260896T1 - Donepezil polykristalle und verfharen zu ihrer herstellung - Google Patents

Donepezil polykristalle und verfharen zu ihrer herstellung

Info

Publication number
ATE260896T1
ATE260896T1 AT98956013T AT98956013T ATE260896T1 AT E260896 T1 ATE260896 T1 AT E260896T1 AT 98956013 T AT98956013 T AT 98956013T AT 98956013 T AT98956013 T AT 98956013T AT E260896 T1 ATE260896 T1 AT E260896T1
Authority
AT
Austria
Prior art keywords
donepezil
polycrystals
production
producing
handleability
Prior art date
Application number
AT98956013T
Other languages
English (en)
Inventor
Akio Imai
Toshiyuki Ichinohe
Takashi Endo
Tomio Tsurugi
Makoto Uemura
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18296352&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE260896(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of ATE260896T1 publication Critical patent/ATE260896T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
AT98956013T 1997-12-05 1998-12-01 Donepezil polykristalle und verfharen zu ihrer herstellung ATE260896T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP33616597 1997-12-05
PCT/JP1998/005405 WO1999029668A1 (fr) 1997-12-05 1998-12-01 Polycristaux de donepezil et leur procede de production

Publications (1)

Publication Number Publication Date
ATE260896T1 true ATE260896T1 (de) 2004-03-15

Family

ID=18296352

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98956013T ATE260896T1 (de) 1997-12-05 1998-12-01 Donepezil polykristalle und verfharen zu ihrer herstellung

Country Status (8)

Country Link
US (1) US6245911B1 (de)
EP (1) EP1048653B1 (de)
AT (1) ATE260896T1 (de)
DE (1) DE69822218T2 (de)
DK (1) DK1048653T3 (de)
ES (1) ES2218869T3 (de)
PT (1) PT1048653E (de)
WO (1) WO1999029668A1 (de)

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US20080081834A1 (en) 2002-07-31 2008-04-03 Lippa Arnold S Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders
US20060014801A1 (en) * 2002-11-22 2006-01-19 The Johns Hopkins University Prevention and treatment of cognitive impairment using (R)-(-)-5-methyl-1-nicotynoyl-2-pyrazoline (MNP) and analogs
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
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US7772399B2 (en) * 2003-04-02 2010-08-10 Hetero Drugs Limited Process for amorphous form of donepezil hydrochloride
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WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
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US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
KR20070083679A (ko) * 2004-09-29 2007-08-24 케마지스 리미티드 약학적으로 순수한 비정질 도네페닐 염산염의 제조를 위한정제된 도네페질 말레산염의 용도
US20060100263A1 (en) * 2004-11-05 2006-05-11 Anthony Basile Antipyretic compositions and methods
CA2590533C (en) * 2004-11-23 2010-09-07 Warner-Lambert Company Llc 7-(2h-pyrazol-3-yl)-3,5-dihydroxy-heptanoic acid derivatives as hmg co-a reductase inhibitors for the treatment of lipidemia
US20060122226A1 (en) * 2004-12-08 2006-06-08 Itai Adin Crystalline forms of Donepezil base
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KR20080039876A (ko) * 2005-07-22 2008-05-07 미리어드 제네틱스, 인크. 높은 약물 충진 제형 및 투여형
EP1915146A4 (de) 2005-07-27 2010-06-02 Dov Pharmaceutical Inc Neuartige 1-aryl-3-azabicyclo[3.1.0]hexane. herstellung und verwendung zur behandlung von neuropsychiatrischen erkrankungen
WO2007018801A1 (en) * 2005-07-28 2007-02-15 Teikoku Pharma Usa, Inc. Gelled donepezil compositions and methods for making and using the same
WO2007108011A2 (en) * 2006-03-20 2007-09-27 Ind-Swift Laboratories Limited Process for the preparation of highly pure donepezil
US20080045725A1 (en) * 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
JP5097359B2 (ja) * 2006-05-09 2012-12-12 久光製薬株式会社 ドネペジル経皮吸収型製剤
US20080033045A1 (en) * 2006-07-07 2008-02-07 Myriad Genetics, Incorporated Treatment of psychiatric disorders
WO2008050351A1 (en) * 2006-10-25 2008-05-02 Jubilant Organosys Limited NOVEL POLYMORPHIC FORMS OF l-BENZYL-4-[(5,6-DIMETHOXY-l-INDANONE)-2-YL]METHYL PIPERIDINE [DONEPEZIL] AND PROCESS FOR PREPARING THE SAME
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JP2010524844A (ja) * 2007-04-26 2010-07-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 認知症のためのシンナミド化合物
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JP5562337B2 (ja) * 2008-12-17 2014-07-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 ドネペジルの多形結晶及びその製造方法
CA2789014C (en) 2010-02-09 2019-01-15 Michela Gallagher Methods and compositions for improving cognitive function
EP2366378A1 (de) 2010-03-01 2011-09-21 Dexcel Pharma Technologies Ltd. Donepezilformulierungen mit verzögerter Freisetzung
WO2011127235A1 (en) 2010-04-07 2011-10-13 Eisai Inc. Combination therapy for the treatment of dementia
WO2011151359A1 (en) 2010-06-02 2011-12-08 Noscira, S.A. Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative
WO2012053016A1 (en) 2010-10-22 2012-04-26 Cadila Healthcare Limited Sustained release pharmaceutical compositions of donepezil
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神***病を処置するための方法および組成物
CA2904767C (en) 2013-03-15 2022-06-21 Agenebio, Inc. Methods and compositions for improving cognitive function
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
AU2014307803A1 (en) 2013-08-16 2016-03-10 Universiteit Maastricht Treatment of cognitive impairment with PDE4 inhibitor
CN107531958B (zh) 2015-05-08 2020-11-06 陶氏环球技术有限责任公司 使用偶氮二甲酰胺/柠檬酸盐混合物作为成核剂来发泡聚烯烃组合物的工艺
WO2016191288A1 (en) 2015-05-22 2016-12-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam
US10369187B2 (en) 2017-02-09 2019-08-06 Vanderbilt University Peptide regulators of JNK family kinases
WO2019068764A1 (de) 2017-10-06 2019-04-11 Lenzing Aktiengesellschaft Vorrichtung für die extrusion von filamenten und herstellung von spinnvliesstoffen
KR20220010547A (ko) 2019-05-17 2022-01-25 렌징 악티엔게젤샤프트 셀룰로오스계 스펀본드 부직포 제조시 방사구 세척 방법 및 장치

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FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
CA2252806C (en) * 1996-06-07 2005-11-22 Eisai Co., Ltd. Polymorphs of donepezil hydrochloride and process for production
JPH1053576A (ja) 1996-06-07 1998-02-24 Eisai Co Ltd 塩酸ドネペジルの多形結晶およびその製造法
TW513409B (en) * 1996-06-07 2002-12-11 Eisai Co Ltd Polymorphs of donepezil hydrochloride

Also Published As

Publication number Publication date
PT1048653E (pt) 2004-07-30
DE69822218D1 (de) 2004-04-08
ES2218869T3 (es) 2004-11-16
EP1048653A1 (de) 2000-11-02
WO1999029668A1 (fr) 1999-06-17
EP1048653B1 (de) 2004-03-03
DE69822218T2 (de) 2005-02-03
US6245911B1 (en) 2001-06-12
EP1048653A4 (de) 2001-03-07
DK1048653T3 (da) 2004-05-24

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