ATE249464T1 - Thienopyrimidinderivate, ihre herstellung und verwendung - Google Patents
Thienopyrimidinderivate, ihre herstellung und verwendungInfo
- Publication number
- ATE249464T1 ATE249464T1 AT96901958T AT96901958T ATE249464T1 AT E249464 T1 ATE249464 T1 AT E249464T1 AT 96901958 T AT96901958 T AT 96901958T AT 96901958 T AT96901958 T AT 96901958T AT E249464 T1 ATE249464 T1 AT E249464T1
- Authority
- AT
- Austria
- Prior art keywords
- agent
- cancer
- animals
- female
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2071795 | 1995-02-08 | ||
JP4015195 | 1995-02-28 | ||
PCT/JP1995/000728 WO1995028405A1 (en) | 1994-04-19 | 1995-04-14 | Bicyclic thiophene derivatives and use as gonadotropin releasing hormone antagonists |
JP27163895 | 1995-10-19 | ||
PCT/JP1996/000263 WO1996024597A1 (en) | 1995-02-08 | 1996-02-07 | Thienopyrimidine derivatives, their production and use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE249464T1 true ATE249464T1 (de) | 2003-09-15 |
Family
ID=27283146
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96901958T ATE249464T1 (de) | 1995-02-08 | 1996-02-07 | Thienopyrimidinderivate, ihre herstellung und verwendung |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0808317B1 (de) |
JP (1) | JP3789538B2 (de) |
KR (1) | KR19980702086A (de) |
CN (1) | CN1064045C (de) |
AT (1) | ATE249464T1 (de) |
AU (1) | AU4632796A (de) |
CA (1) | CA2211969A1 (de) |
DE (1) | DE69629914T2 (de) |
UY (1) | UY23948A1 (de) |
WO (1) | WO1996024597A1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0906115A1 (de) * | 1996-04-30 | 1999-04-07 | Takeda Chemical Industries, Ltd. | Kombinierte anwendung von gnrh agonist und antagonist |
US6413724B1 (en) | 1996-10-28 | 2002-07-02 | Versicor, Inc. | Solid phase and combinatorial library syntheses of fused 2,4-pyrimidinediones |
AU6908398A (en) * | 1996-10-28 | 1998-05-22 | Versicor Inc | Fused 2,4-pyrimidinedione combinatorial libraries and biologically active fused 2,4-pyramidinediones |
US6025371A (en) * | 1996-10-28 | 2000-02-15 | Versicor, Inc. | Solid phase and combinatorial library syntheses of fused 2,4-pyrimidinediones |
RU2233284C2 (ru) | 1999-03-24 | 2004-07-27 | Такеда Кемикал Индастриз, Лтд. | Тиенопиримидиновые производные, способ их получения, фармацевтическая композиция и способ антагонизации гонадотропин-рилизинг гормона |
JP4652520B2 (ja) * | 1999-03-24 | 2011-03-16 | 武田薬品工業株式会社 | チエノピリミジン化合物、その製造法および用途 |
TWI225863B (en) * | 1999-03-24 | 2005-01-01 | Takeda Chemical Industries Ltd | Thienopyrimidine compounds, their production and use |
KR100814269B1 (ko) | 2000-01-25 | 2008-03-18 | 뉴로크린 바이오사이언시즈 인코퍼레이티드 | 고나도트로핀-분비 호르몬 수용체 길항제 및 이를 포함하는 약제학적 조성물 |
US6849738B2 (en) | 2000-02-29 | 2005-02-01 | Takeda Chemical Industries, Ltd. | Processes for the production of thienopyrimidine derivatives |
US20030134863A1 (en) * | 2000-04-13 | 2003-07-17 | Shuichi Furuya | Preventives/remedies for alzheimer's disease |
WO2002047722A1 (fr) * | 2000-12-15 | 2002-06-20 | Takeda Chemical Industries, Ltd. | Compositions medicinales agoniste ou antagoniste de la gonadoliberine non peptidyl, methode de production et utilisation desdites compositions |
US7569570B2 (en) | 2002-01-30 | 2009-08-04 | Takeda Pharmaceutical Company Limited | Thienopyrimidines, process for preparing the same and use thereof |
AU2003236039A1 (en) * | 2002-04-12 | 2003-10-27 | Takeda Pharmaceutical Company Limited | Preventives/remedies for hotflash |
EP1591446B1 (de) | 2003-01-29 | 2013-03-06 | Takeda Pharmaceutical Company Limited | Thienopyrimidinverbindungen und deren Verwendung |
JP2008094846A (ja) * | 2003-01-29 | 2008-04-24 | Takeda Chem Ind Ltd | チエノピリミジン化合物およびその用途 |
GB0307777D0 (en) | 2003-04-04 | 2003-05-07 | Medical Res Council | Conjugate compounds |
DE102004033902A1 (de) | 2004-07-14 | 2006-02-16 | Zentaris Gmbh | Neue Tetrahydrocarbazolderivate mit verbesserter biologischer Wirkung und verbesserter Löslichkeit als Liganden für G-Protein gekoppelte Rezeptoren (GPCR's) |
JPWO2006083005A1 (ja) * | 2005-02-03 | 2008-06-26 | 武田薬品工業株式会社 | 縮合ピリミジン誘導体およびその用途 |
CA2682519A1 (en) | 2007-04-18 | 2008-11-06 | Kissei Pharmaceutical Co., Ltd. | Fused heterocyclic derivative, pharmaceutical composition comprising the derivative, and use of the composition for medical purposes |
CA2682400A1 (en) | 2007-04-18 | 2008-11-06 | Kissei Pharmaceutical Co., Ltd. | Fused heterocyclic derivative, pharmaceutical composition comprising the derivative, and use of the composition for medical purposes |
JP5308342B2 (ja) * | 2007-09-18 | 2013-10-09 | キッセイ薬品工業株式会社 | 含窒素縮合環誘導体、それを含有する医薬組成物およびその医薬用途 |
EP2095818A1 (de) | 2008-02-29 | 2009-09-02 | AEterna Zentaris GmbH | Verwendung von LHRH-Antagonisten in nicht-kastrierenden Dosen |
EP2329823A4 (de) | 2008-09-03 | 2013-04-03 | Takeda Pharmaceutical | Verfahren zur erhöhung der absorptionsfähigkeit eines präparats sowie präparat mit erhöhter absorptionsfähigkeit |
CN110194776B (zh) * | 2019-06-27 | 2021-05-28 | 四川伊诺达博医药科技有限公司 | 一种瑞卢戈利的合成方法 |
US20220267347A1 (en) * | 2019-07-29 | 2022-08-25 | Sunshine Lake Pharma Co., Ltd. | Substituted pyrimidinedione compounds and uses thereof |
CN111574534B (zh) * | 2020-05-25 | 2021-06-04 | 东莞市东阳光新药研发有限公司 | 苯基取代的噻吩并[2,3-d]嘧啶-2,4(1H,3H)-二酮类化合物及其用途 |
CN116438181A (zh) * | 2020-09-29 | 2023-07-14 | 广东东阳光药业有限公司 | 磺酰胺基取代的杂芳基嘧啶二酮类化合物及其用途 |
CN116096371A (zh) * | 2020-09-29 | 2023-05-09 | 广东东阳光药业有限公司 | 含有饱和含氧杂环基的嘧啶二酮类化合物及其用途 |
KR102649886B1 (ko) * | 2021-07-21 | 2024-03-22 | 충남대학교산학협력단 | 신규한 피리미딘-4-온 화합물 및 이를 포함하는 항암제 조성물 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2006505A1 (de) * | 1970-02-13 | 1971-08-26 | Merck Patent Gmbh, 6100 Darmstadt | Isoflavanoid ather und Verfahren zu ihrer Herstellung |
CA2036618C (en) * | 1990-02-22 | 2002-10-29 | Akira Morimoto | Fused thiophene derivatives, their production and use |
TW276256B (de) * | 1993-08-26 | 1996-05-21 | Takeda Pharm Industry Co Ltd |
-
1995
- 1995-04-18 UY UY23948A patent/UY23948A1/es not_active Application Discontinuation
-
1996
- 1996-02-07 AT AT96901958T patent/ATE249464T1/de not_active IP Right Cessation
- 1996-02-07 WO PCT/JP1996/000263 patent/WO1996024597A1/en active IP Right Grant
- 1996-02-07 JP JP02134296A patent/JP3789538B2/ja not_active Expired - Fee Related
- 1996-02-07 EP EP96901958A patent/EP0808317B1/de not_active Expired - Lifetime
- 1996-02-07 CN CN96191854A patent/CN1064045C/zh not_active Expired - Fee Related
- 1996-02-07 KR KR1019970705481A patent/KR19980702086A/ko not_active IP Right Cessation
- 1996-02-07 AU AU46327/96A patent/AU4632796A/en not_active Abandoned
- 1996-02-07 DE DE69629914T patent/DE69629914T2/de not_active Expired - Lifetime
- 1996-02-07 CA CA002211969A patent/CA2211969A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN1064045C (zh) | 2001-04-04 |
CN1173868A (zh) | 1998-02-18 |
AU4632796A (en) | 1996-08-27 |
JP3789538B2 (ja) | 2006-06-28 |
EP0808317A1 (de) | 1997-11-26 |
DE69629914D1 (de) | 2003-10-16 |
WO1996024597A1 (en) | 1996-08-15 |
EP0808317B1 (de) | 2003-09-10 |
KR19980702086A (ko) | 1998-07-15 |
DE69629914T2 (de) | 2004-07-15 |
JPH09169768A (ja) | 1997-06-30 |
UY23948A1 (es) | 2001-10-25 |
CA2211969A1 (en) | 1996-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |