ATE246009T1 - Thiolierung von peptiden zur strahlendiagnostik und strahlentherapie auf radionuklidbasis - Google Patents
Thiolierung von peptiden zur strahlendiagnostik und strahlentherapie auf radionuklidbasisInfo
- Publication number
- ATE246009T1 ATE246009T1 AT96919062T AT96919062T ATE246009T1 AT E246009 T1 ATE246009 T1 AT E246009T1 AT 96919062 T AT96919062 T AT 96919062T AT 96919062 T AT96919062 T AT 96919062T AT E246009 T1 ATE246009 T1 AT E246009T1
- Authority
- AT
- Austria
- Prior art keywords
- peptide
- thiol
- radiation
- thiolation
- radionuclide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48309895A | 1995-06-07 | 1995-06-07 | |
US08/483,095 US5746996A (en) | 1994-06-03 | 1995-06-07 | Thiolation of peptides for radionuclide-based radiodetection and radiotherapy |
PCT/US1996/008693 WO1996040289A1 (en) | 1995-06-07 | 1996-06-07 | Thiolation of peptides for radionuclide-based radiodetection and radiotherapy |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE246009T1 true ATE246009T1 (de) | 2003-08-15 |
Family
ID=27047528
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96919062T ATE246009T1 (de) | 1995-06-07 | 1996-06-07 | Thiolierung von peptiden zur strahlendiagnostik und strahlentherapie auf radionuklidbasis |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0831936B1 (de) |
JP (1) | JPH11507623A (de) |
AT (1) | ATE246009T1 (de) |
AU (1) | AU709219B2 (de) |
CA (1) | CA2222966C (de) |
DE (1) | DE69629295T2 (de) |
ES (1) | ES2206579T3 (de) |
WO (1) | WO1996040289A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6576746B2 (en) | 1998-10-13 | 2003-06-10 | Immunomedics, Inc. | Site-specific labeling of disulfide-containing targeting vectors |
AU755783B2 (en) * | 1998-10-13 | 2002-12-19 | Immunomedics Inc. | Site-specific labeling of disulfide-containing targeting vectors |
EP1749026B1 (de) | 2004-05-24 | 2011-11-23 | Institut de Cardiologie de Montréal | Markierte adrenomedullinderivate und deren verwendung zur bilddarstellung und therapie |
WO2008138141A1 (en) * | 2007-05-11 | 2008-11-20 | Institut De Cardiologie De Montréal | Labelled adrenomedullin derivatives and their use for imaging and therapy. |
JP2009051784A (ja) * | 2007-08-28 | 2009-03-12 | Inst Nuclear Energy Research Rocaec | 癌を抑制する放射性物質及びその調整方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5180816A (en) * | 1988-08-24 | 1993-01-19 | Centocor | One vial method for labeling protein/linker conjugates with technetium-99M |
CA2102633A1 (en) * | 1991-06-03 | 1992-12-04 | Peter H. Cox | Radiolabelled somatostatin derivatives, their preparation and use |
US5225180A (en) * | 1991-09-10 | 1993-07-06 | Diatech, Inc. | Technetium-99m labeled somatostatin-derived peptides for imaging |
EP0629133B1 (de) * | 1992-01-03 | 2000-11-29 | Rhomed, Incorporated | Pharmazeutische anwendungen auf der basis von peptid-metall-ionen |
IL113610A0 (en) * | 1994-06-03 | 1995-08-31 | Immunomedics Inc | A method of radiolabeling a protein, radiolabeled proteins prepared thereby and diagnostic kits containing the same |
-
1996
- 1996-06-07 EP EP96919062A patent/EP0831936B1/de not_active Expired - Lifetime
- 1996-06-07 AU AU61500/96A patent/AU709219B2/en not_active Ceased
- 1996-06-07 DE DE69629295T patent/DE69629295T2/de not_active Expired - Lifetime
- 1996-06-07 CA CA002222966A patent/CA2222966C/en not_active Expired - Fee Related
- 1996-06-07 ES ES96919062T patent/ES2206579T3/es not_active Expired - Lifetime
- 1996-06-07 JP JP9501201A patent/JPH11507623A/ja active Pending
- 1996-06-07 AT AT96919062T patent/ATE246009T1/de not_active IP Right Cessation
- 1996-06-07 WO PCT/US1996/008693 patent/WO1996040289A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
WO1996040289A1 (en) | 1996-12-19 |
DE69629295D1 (de) | 2003-09-04 |
CA2222966C (en) | 2007-03-13 |
EP0831936A1 (de) | 1998-04-01 |
AU6150096A (en) | 1996-12-30 |
EP0831936B1 (de) | 2003-07-30 |
ES2206579T3 (es) | 2004-05-16 |
JPH11507623A (ja) | 1999-07-06 |
AU709219B2 (en) | 1999-08-26 |
DE69629295T2 (de) | 2004-05-13 |
EP0831936A4 (de) | 2001-05-16 |
CA2222966A1 (en) | 1996-12-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0831936 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |