ATE238285T1 - Pyrimidin-derivate - Google Patents

Pyrimidin-derivate

Info

Publication number
ATE238285T1
ATE238285T1 AT95940471T AT95940471T ATE238285T1 AT E238285 T1 ATE238285 T1 AT E238285T1 AT 95940471 T AT95940471 T AT 95940471T AT 95940471 T AT95940471 T AT 95940471T AT E238285 T1 ATE238285 T1 AT E238285T1
Authority
AT
Austria
Prior art keywords
alkyl
derivative
salt
present
pyrimidine derivatives
Prior art date
Application number
AT95940471T
Other languages
English (en)
Inventor
Mitsuteru Hirata
Takeo Deushi
Yoshio Takahashi
Masahiro Tamura
Takeshi Ohshima
Toshiaki Oda
Hiroyuki Sonoki
Masami Shiratsuchi
Original Assignee
Kowa Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co filed Critical Kowa Co
Application granted granted Critical
Publication of ATE238285T1 publication Critical patent/ATE238285T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/69—Benzenesulfonamido-pyrimidines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT95940471T 1994-12-28 1995-12-19 Pyrimidin-derivate ATE238285T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP32732994 1994-12-28
JP16945495 1995-07-05
PCT/JP1995/002605 WO1996020177A1 (fr) 1994-12-28 1995-12-19 Derives pyrimidiniques

Publications (1)

Publication Number Publication Date
ATE238285T1 true ATE238285T1 (de) 2003-05-15

Family

ID=26492784

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95940471T ATE238285T1 (de) 1994-12-28 1995-12-19 Pyrimidin-derivate

Country Status (12)

Country Link
US (2) US6008224A (de)
EP (1) EP0801062B1 (de)
CN (1) CN1171785A (de)
AT (1) ATE238285T1 (de)
CA (1) CA2207100C (de)
DE (1) DE69530516T2 (de)
ES (1) ES2196090T3 (de)
FI (1) FI972795A0 (de)
HU (1) HUT77534A (de)
NO (1) NO973001L (de)
PT (1) PT801062E (de)
WO (1) WO1996020177A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5883092A (en) * 1995-09-06 1999-03-16 Kowa Co., Ltd. Pyrimidine derivatives as endothelin antagonists
US7566452B1 (en) * 1999-05-04 2009-07-28 New York University Cancer treatment with endothelin receptor antagonists
CA2315614C (en) * 1999-07-29 2004-11-02 Pfizer Inc. Pyrazoles
PT1254121E (pt) * 2000-01-25 2006-06-30 Hoffmann La Roche Preparacao de sulfonamidas
US6387915B2 (en) 2000-05-31 2002-05-14 Pfizer Inc. Isoxazole-sulfonamide endothelin antagonists
US6670362B2 (en) 2000-09-20 2003-12-30 Pfizer Inc. Pyridazine endothelin antagonists
US11446303B2 (en) * 2019-06-21 2022-09-20 Tosk, Inc. Uridine phosphorylase (UPase) inhibitors for treatment of liver conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2086544C1 (ru) * 1991-06-13 1997-08-10 Хоффманн-Ля Рош АГ Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина
TW394761B (en) * 1993-06-28 2000-06-21 Hoffmann La Roche Novel Sulfonylamino Pyrimidines
IL111959A (en) * 1993-12-17 2000-07-16 Tanabe Seiyaku Co N-(polysubstituted pyrimidin-4-yl) benzenesulfonamide derivatives their preparation and pharmaceutical compositions containing them
US5883092A (en) * 1995-09-06 1999-03-16 Kowa Co., Ltd. Pyrimidine derivatives as endothelin antagonists

Also Published As

Publication number Publication date
AU4190096A (en) 1996-07-19
DE69530516T2 (de) 2003-12-24
US6337334B1 (en) 2002-01-08
FI972795A (fi) 1997-06-27
EP0801062A4 (de) 1998-04-29
NO973001L (no) 1997-08-27
HUT77534A (hu) 1998-05-28
CN1171785A (zh) 1998-01-28
CA2207100C (en) 2008-02-19
EP0801062A1 (de) 1997-10-15
US6008224A (en) 1999-12-28
WO1996020177A1 (fr) 1996-07-04
DE69530516D1 (de) 2003-05-28
FI972795A0 (fi) 1997-06-27
AU696216B2 (en) 1998-09-03
CA2207100A1 (en) 1996-07-04
EP0801062B1 (de) 2003-04-23
ES2196090T3 (es) 2003-12-16
NO973001D0 (no) 1997-06-27
PT801062E (pt) 2003-08-29

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties