ATE235956T1 - Verfahren zur herstellung von partikeln - Google Patents

Verfahren zur herstellung von partikeln

Info

Publication number
ATE235956T1
ATE235956T1 AT00942295T AT00942295T ATE235956T1 AT E235956 T1 ATE235956 T1 AT E235956T1 AT 00942295 T AT00942295 T AT 00942295T AT 00942295 T AT00942295 T AT 00942295T AT E235956 T1 ATE235956 T1 AT E235956T1
Authority
AT
Austria
Prior art keywords
vehicles
vehicle
solvent
target substance
dispersion
Prior art date
Application number
AT00942295T
Other languages
English (en)
Inventor
Mazen Hermiz Hanna
Peter York
Original Assignee
Bradford Particle Design Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bradford Particle Design Ltd filed Critical Bradford Particle Design Ltd
Application granted granted Critical
Publication of ATE235956T1 publication Critical patent/ATE235956T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
    • B01D11/0407—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solute
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
    • B01D11/0411—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solvent and as anti-solvent for the solute, e.g. formation of particles from solutions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0488—Flow sheets

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Glass Compositions (AREA)
AT00942295T 1999-07-07 2000-07-07 Verfahren zur herstellung von partikeln ATE235956T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9915975.8A GB9915975D0 (en) 1999-07-07 1999-07-07 Method for the formation of particles
PCT/GB2000/002606 WO2001003821A1 (en) 1999-07-07 2000-07-07 Method of particle formation

Publications (1)

Publication Number Publication Date
ATE235956T1 true ATE235956T1 (de) 2003-04-15

Family

ID=10856857

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00942295T ATE235956T1 (de) 1999-07-07 2000-07-07 Verfahren zur herstellung von partikeln

Country Status (12)

Country Link
US (2) US6860907B1 (de)
EP (1) EP1191999B1 (de)
JP (1) JP4490016B2 (de)
AT (1) ATE235956T1 (de)
AU (1) AU773548B2 (de)
CA (1) CA2376593C (de)
DE (1) DE60001944T2 (de)
DK (1) DK1191999T3 (de)
ES (1) ES2195908T3 (de)
GB (2) GB9915975D0 (de)
MX (1) MXPA01013259A (de)
WO (1) WO2001003821A1 (de)

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FR2815540B1 (fr) † 2000-10-19 2005-06-10 Separex Sa Procede de fabrication de tres fines particules constituees d'un principe insere dans une molecule hote
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GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
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EP1440082B1 (de) 2001-10-22 2011-09-28 Dompé S.P.A. Verfahren durch gebrauch von überkritischen flüssigkeiten: herstellung von proteinmikropartikeln und ihre stabilisierung
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CN108969555B (zh) * 2017-09-25 2021-08-10 安徽九鑫药业有限公司 一种补肾、益精血、增强免疫力的淫羊藿中药组合物的制备方法
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CN112657301A (zh) * 2020-12-01 2021-04-16 大连理工大学 一种超临界气固分离装置及方法
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Also Published As

Publication number Publication date
MXPA01013259A (es) 2002-12-13
AU773548B2 (en) 2004-05-27
WO2001003821A1 (en) 2001-01-18
US6860907B1 (en) 2005-03-01
DK1191999T3 (da) 2003-07-21
GB2354968A (en) 2001-04-11
EP1191999A1 (de) 2002-04-03
DE60001944T2 (de) 2003-12-24
EP1191999B1 (de) 2003-04-02
US7150766B2 (en) 2006-12-19
JP2003504178A (ja) 2003-02-04
ES2195908T3 (es) 2003-12-16
AU5699000A (en) 2001-01-30
GB9915975D0 (en) 1999-09-08
US20050206023A1 (en) 2005-09-22
GB2354968B (en) 2001-09-12
JP4490016B2 (ja) 2010-06-23
GB0016618D0 (en) 2000-08-23
CA2376593A1 (en) 2001-01-18
CA2376593C (en) 2009-12-01
DE60001944D1 (de) 2003-05-08

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