ATE256497T1 - Verfahren zur mikroverkapselung und elektrostatische behandlung - Google Patents

Verfahren zur mikroverkapselung und elektrostatische behandlung

Info

Publication number
ATE256497T1
ATE256497T1 AT99923047T AT99923047T ATE256497T1 AT E256497 T1 ATE256497 T1 AT E256497T1 AT 99923047 T AT99923047 T AT 99923047T AT 99923047 T AT99923047 T AT 99923047T AT E256497 T1 ATE256497 T1 AT E256497T1
Authority
AT
Austria
Prior art keywords
microcapsules
methods
forming
hydrophilic
hydrophobic
Prior art date
Application number
AT99923047T
Other languages
English (en)
Inventor
Dennis R Morrison
Benjamin Mosier
Original Assignee
Nasa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nasa filed Critical Nasa
Application granted granted Critical
Publication of ATE256497T1 publication Critical patent/ATE256497T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0028—Disruption, e.g. by heat or ultrasounds, sonophysical or sonochemical activation, e.g. thermosensitive or heat-sensitive liposomes, disruption of calculi with a medicinal preparation and ultrasounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]
    • Y10T428/2985—Solid-walled microcapsule from synthetic polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Physical Vapour Deposition (AREA)
AT99923047T 1998-05-15 1999-05-14 Verfahren zur mikroverkapselung und elektrostatische behandlung ATE256497T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/079,770 US6103271A (en) 1994-12-02 1998-05-15 Microencapsulation and electrostatic processing method
PCT/US1999/010654 WO1999059714A1 (en) 1998-05-15 1999-05-14 Microencapsulation and electrostatic processing method

Publications (1)

Publication Number Publication Date
ATE256497T1 true ATE256497T1 (de) 2004-01-15

Family

ID=22152707

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99923047T ATE256497T1 (de) 1998-05-15 1999-05-14 Verfahren zur mikroverkapselung und elektrostatische behandlung

Country Status (6)

Country Link
US (1) US6103271A (de)
EP (1) EP1079918B1 (de)
AT (1) ATE256497T1 (de)
DE (1) DE69913685T2 (de)
ES (1) ES2214028T3 (de)
WO (1) WO1999059714A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100541753B1 (ko) * 1999-07-27 2006-01-10 가부시키가이샤 시세이도 마이크로캡슐 및 그 제조방법
ES2328446T5 (es) 2000-02-04 2014-02-27 Children's Hospital Research Foundation Uso de lipasa ácida lisosomal para tratar la aterosclerosis y enfermedades asociadas
WO2001074431A2 (en) * 2000-04-03 2001-10-11 Battelle Memorial Institute Dispensing devices and liquid formulations
WO2002043700A2 (en) * 2000-11-30 2002-06-06 Vectura Limited Particles for use in a pharmaceutical composition
EP2283818B1 (de) 2000-11-30 2017-08-02 Vectura Limited Herstellungsverfahren für Partikel zur Verwendung in einer Arrzneizusammensetzung
AU3664102A (en) * 2000-12-01 2002-06-11 Battelle Memorial Institute Method for stabilizing biomolecules in liquid formulations
US20050156340A1 (en) 2004-01-20 2005-07-21 E Ink Corporation Preparation of capsules
US6890592B2 (en) * 2002-03-13 2005-05-10 Appleton Papers Inc. Uniform microcapsules
AU2003229693A1 (en) * 2002-04-19 2003-11-03 Biohurt Biograde Gmbh & Co. Kg Matrix comprising a bioactive component containing phospholipid
DE10217557A1 (de) * 2002-04-19 2003-11-06 Degussa Bioactives Gmbh Funktionsnahrungsmittel enthaltend eine Phospholipid-haltige stabile Matrix
US6958848B2 (en) * 2002-05-23 2005-10-25 E Ink Corporation Capsules, materials for use therein and electrophoretic media and displays containing such capsules
US20050058689A1 (en) 2003-07-03 2005-03-17 Reactive Surfaces, Ltd. Antifungal paints and coatings
FR2850040B1 (fr) * 2003-01-20 2005-03-11 Centre Nat Rech Scient Systemes pour microencapsulation et leurs applications
US7914714B2 (en) * 2003-05-14 2011-03-29 The Regents Of The University Of Colorado Methods and apparatus using electrostatic atomization to form liquid vesicles
US7101617B2 (en) 2003-07-10 2006-09-05 Motorola, Inc. Silicone dispensing with a conformal film
US7094045B2 (en) * 2003-12-09 2006-08-22 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microencapsulation system and method
US7182810B2 (en) * 2004-04-16 2007-02-27 Canadian Space Agency Protein temperature evaporation-controlled crystallization device and method thereof
WO2005122734A2 (en) * 2004-06-14 2005-12-29 The Research Foundation Of State University Of New York Nanosphere/microsphere delivery system for the treatment of spinal cord injury
EP1627911A1 (de) 2004-08-20 2006-02-22 Schering Aktiengesellschaft Waschvorrichtung
US20060037634A1 (en) * 2004-08-20 2006-02-23 Vorholz Jessica F Washing apparatus
US20060071357A1 (en) * 2004-09-27 2006-04-06 Pilon Laurent G Method and apparatus for liquid microencapsulation with polymers using ultrasonic atomization
US20060147536A1 (en) * 2004-12-30 2006-07-06 Fiore Robert A Method for removing fluids containing dissolved or suspended carbohydrates, lipids, metals, salts, and/or toxins from biological systems
US20090297496A1 (en) * 2005-09-08 2009-12-03 Childrens Hospital Medical Center Lysosomal Acid Lipase Therapy for NAFLD and Related Diseases
US7341986B1 (en) * 2006-02-03 2008-03-11 Murtie Nina Kalusha Cleaning concentrate consisting of extra virgin olive oil and isopropyl alcohol
US8297959B2 (en) * 2006-05-03 2012-10-30 Terapia Celular, Ln, Inc. Systems for producing multilayered particles, fibers and sprays and methods for administering the same
US7985058B2 (en) * 2007-01-12 2011-07-26 Mark Gray Method and apparatus for making uniformly sized particles
ES2347119B2 (es) * 2009-04-22 2011-04-28 Universidad De Santiago De Compostela Nanocapsulas de poliarginina.
KR20120061821A (ko) * 2009-08-31 2012-06-13 산요가세이고교 가부시키가이샤 실리콘 잉곳 슬라이스용 수용성 절삭액
ES2481940B1 (es) * 2012-12-17 2015-05-06 Universidade De Santiago De Compostela Nanocápsulas de protamina
CN112439540B (zh) * 2019-08-30 2022-08-30 中国石油天然气股份有限公司 一种轻重矿物分离装置及方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4201691A (en) * 1978-01-16 1980-05-06 Exxon Research & Engineering Co. Liquid membrane generator
JPS5719662A (en) * 1980-07-09 1982-02-01 Fuji Photo Film Co Ltd Preparation of microcapsule reagent for immune reaction
JPS57110332A (en) * 1980-12-13 1982-07-09 Kanzaki Paper Mfg Co Ltd Preparation of microcapsule
US4921706A (en) * 1984-11-20 1990-05-01 Massachusetts Institute Of Technology Unilamellar lipid vesicles and method for their formation
US4619795A (en) * 1984-12-24 1986-10-28 Technicon Instruments Corp. Method for preparing lipid vesicles
US4936901A (en) * 1986-07-09 1990-06-26 Monsanto Company Formulations of water-dispersible granules and process for preparation thereof
US4909933A (en) * 1988-09-15 1990-03-20 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Apparatus for mixing solutions in low gravity environments
US5165994A (en) * 1990-06-05 1992-11-24 University Of Delaware Spontaneous equilbrium surfactant vesicles
US5545423A (en) * 1991-11-25 1996-08-13 Vivorx, Inc. Cytoprotective, biocompatible, retrievable macrocapsule containment systems for biologically active materials
US5827531A (en) * 1994-12-02 1998-10-27 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microcapsules and methods for making
US5702182A (en) * 1996-07-24 1997-12-30 Instrumentation Technology Associates, Inc. Apparatus for mixing selected volumes of liquids

Also Published As

Publication number Publication date
EP1079918A1 (de) 2001-03-07
DE69913685D1 (de) 2004-01-29
ES2214028T3 (es) 2004-09-01
EP1079918B1 (de) 2003-12-17
WO1999059714A1 (en) 1999-11-25
DE69913685T2 (de) 2004-10-07
US6103271A (en) 2000-08-15

Similar Documents

Publication Publication Date Title
ATE256497T1 (de) Verfahren zur mikroverkapselung und elektrostatische behandlung
Cheung Shum et al. Microfluidic fabrication of water-in-water (w/w) jets and emulsions
Cacace et al. Aqueous emulsion droplets stabilized by lipid vesicles as microcompartments for biomimetic mineralization
Chaouchi et al. Acetaminophen extraction by emulsion liquid membrane using Aliquat 336 as extractant
RU2581368C2 (ru) Устройство и способ солюбилизации, выделения, удаления и осуществления взаимодействия карбоновых кислот в маслах, жирах, водных или органических растворах с помощью микро- или наноэмульсификации
Vicente et al. Impact of surface active ionic liquids on the cloud points of nonionic surfactants and the formation of aqueous micellar two-phase systems
DE60035669D1 (de) Neue in einem hydrogel isolierte cochleat-formulierungen, verfahren zu deren herstellung und deren verwendung zur verabreichung von biologisch aktiven molekülen
WO2007127439A3 (en) Compositions comprising fusogenic proteins or polypeptides derived from prosaposin for application in transmembrane drug delivery systems
DE69415998D1 (de) Verfahren zur formung von partikeln unter verwendung einer überkritischen flüssigkeit so hergestellte aerogelpartikel und aerogelpartikel enthaltenden antiperspirantien
DE60209516D1 (de) Prozess zur Herstellung kristalliner Partikel von Fluticason, Beclomethason, Salmeterol und Salbutamol
ATE333312T1 (de) Verfahren zur herstellung von feinkörnigen medizinischen substanzen
Su et al. Bubble-propelled hierarchical porous micromotors from evolved double emulsions
US9682181B2 (en) Device and method for removing protein-bound toxins from the blood of patients using a high-frequency, electromagnetic field and an electrostatic direct current field
JP2016504312A5 (de)
Agrawal et al. A review of tangential flow filtration: process development and applications in the pharmaceutical industry
CN107206331A (zh) 选择性透过膜及其制造方法
Sharma et al. Incorporation of melittin enhances interfacial fluidity of bicontinuous microemulsions
DE60304728D1 (de) Verfahren zur herstellung von emulsionen
Madadlou et al. All-aqueous emulsions as miniaturized chemical reactors in the food and bioprocess technology
Zhang et al. Short review on liquid membrane technology and their applications in biochemical engineering
US20110011809A1 (en) Water purification system
ATE92075T1 (de) Verfahren zur gewinnung aktiver proteine aus einer biologisch inaktiven form.
WO2003103742A3 (en) METHOD AND APPARATUS FOR OZONE DECONTAMINATION OF BIOLOGICAL FLUIDS
Duša et al. Nanoplasmonic sensing and capillary electrophoresis for fast screening of interactions between phosphatidylcholine biomembranes and surfactants
DE69820580D1 (de) Verfahren zur Abtrennung von Metallen durch micellare Ultrafiltration, geeignet zur Behandlung von radioaktiven Abfallstoffen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties