ATE230923T1 - Verfahren und zusammensetzungen zur herstellung getrockneter, lagerungsstabiler blutplättchen - Google Patents

Verfahren und zusammensetzungen zur herstellung getrockneter, lagerungsstabiler blutplättchen

Info

Publication number
ATE230923T1
ATE230923T1 AT98904260T AT98904260T ATE230923T1 AT E230923 T1 ATE230923 T1 AT E230923T1 AT 98904260 T AT98904260 T AT 98904260T AT 98904260 T AT98904260 T AT 98904260T AT E230923 T1 ATE230923 T1 AT E230923T1
Authority
AT
Austria
Prior art keywords
compositions
storage
producing dried
stable blood
blood plates
Prior art date
Application number
AT98904260T
Other languages
English (en)
Inventor
Valentine Charlton Menys
Diana Johanna Phipps
Lynda Mary Grandage
Bruce Joseph Roser
Original Assignee
Elan Drug Delivery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Drug Delivery Ltd filed Critical Elan Drug Delivery Ltd
Application granted granted Critical
Publication of ATE230923T1 publication Critical patent/ATE230923T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent
AT98904260T 1997-02-07 1998-02-06 Verfahren und zusammensetzungen zur herstellung getrockneter, lagerungsstabiler blutplättchen ATE230923T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3749397P 1997-02-07 1997-02-07
PCT/GB1998/000375 WO1998034478A1 (en) 1997-02-07 1998-02-06 Methods and compositions for producing dried, storage-stable platelets

Publications (1)

Publication Number Publication Date
ATE230923T1 true ATE230923T1 (de) 2003-02-15

Family

ID=21894636

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98904260T ATE230923T1 (de) 1997-02-07 1998-02-06 Verfahren und zusammensetzungen zur herstellung getrockneter, lagerungsstabiler blutplättchen

Country Status (12)

Country Link
US (1) US6221575B1 (de)
EP (1) EP0967862B1 (de)
JP (1) JP2001511174A (de)
CN (1) CN1246778A (de)
AT (1) ATE230923T1 (de)
AU (1) AU732274B2 (de)
CA (1) CA2279376A1 (de)
DE (1) DE69810755T2 (de)
DK (1) DK0967862T3 (de)
ES (1) ES2190063T3 (de)
WO (1) WO1998034478A1 (de)
ZA (1) ZA981031B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9914412D0 (en) * 1999-06-22 1999-08-18 Worrall Eric E Method for the preservation of viruses,bacteria and biomolecules
ES2190991T3 (es) 1999-11-12 2003-09-01 Elan Drug Delivery Ltd Estabilizacion de plaquetas.
DE19964109A1 (de) 1999-12-29 2001-07-05 Dade Behring Marburg Gmbh Gebrauchsfertiges langzeitstabiles Ristocetin Cofaktor Testreagenz
WO2001058266A1 (en) * 2000-02-10 2001-08-16 The Regents Of The University Of California Therapeutic platelets and methods
DE10010959A1 (de) * 2000-03-06 2001-09-20 Eppendorf Geraetebau Netheler Verfahren zum Übertragen von Material in einem Zellsystem
US6653062B1 (en) * 2000-07-26 2003-11-25 Wisconsin Alumni Research Foundation Preservation and storage medium for biological materials
US8101077B2 (en) * 2001-05-07 2012-01-24 Sivaprasad Sukavaneshvar Device for separating platelets from fluid suspensions
US7011852B2 (en) * 2001-05-07 2006-03-14 Hemogenesis, Llc Separation of platelets from whole blood for use as a healant
WO2004011616A2 (en) * 2002-07-26 2004-02-05 The General Hospital Corporation Systems and methods for cell preservation
AU2003304289A1 (en) * 2002-11-29 2005-01-21 The Regents Of The University Of California A method and therapeutic platelets
WO2005116081A2 (en) 2004-05-24 2005-12-08 Genvault Corporation Stable protein storage and stable nucleic acid storage in recoverable form
US7811558B2 (en) * 2004-08-12 2010-10-12 Cellphire, Inc. Use of stabilized platelets as hemostatic agent
US20060035383A1 (en) * 2004-08-12 2006-02-16 David Ho Dry platelet preparations for use in diagnostics
EP1784639B1 (de) * 2004-08-12 2010-01-20 CELLPHIRE, Inc. Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren
US9393215B2 (en) * 2005-12-02 2016-07-19 Novartis Ag Nanoparticles for use in immunogenic compositions
US8097403B2 (en) * 2006-12-14 2012-01-17 Cellphire, Inc. Freeze-dried platelets, method of making and method of use as a diagnostic agent
US20090081785A1 (en) * 2007-09-24 2009-03-26 Hememics Biotechnologies, Inc. Desiccated Biologics And Methods Of Preparing The Same
US20090090022A1 (en) * 2007-10-09 2009-04-09 Hememics Biotechnologies, Inc. Desiccation Chamber and Methods for Drying Biological Materials
US20100209957A1 (en) * 2008-06-20 2010-08-19 Genvault Corporation Biosample storage devices and methods of use thereof
WO2010031007A2 (en) 2008-09-12 2010-03-18 Genvault Corporation Matrices and media for storage and stabilization of biomolecules
US8734854B2 (en) * 2009-07-09 2014-05-27 Orogen Biosciences Inc. Process for removing growth factors from platelets
US20110183311A1 (en) * 2010-01-27 2011-07-28 David Ho Dry platelet preparations for use in diagnostics
EP2547760A4 (de) * 2010-02-17 2014-01-01 Hememics Biotechnologies Inc Konservierungslösungen für biologika und zugehörige verfahren
WO2011124280A1 (en) * 2010-04-08 2011-10-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Zeodration method for the preservation of blood platelets
CN101957364A (zh) * 2010-09-19 2011-01-26 李勇 冻干型血小板抗原谱细胞的制备方法
CN102327288B (zh) * 2011-10-17 2012-11-14 济南环肽医药科技有限公司 一种注射用血小板冻干粉制剂及其制备方法
WO2015191599A2 (en) 2014-06-09 2015-12-17 Terumo Bct, Inc. Lyophilization
CN104964909B (zh) * 2015-05-28 2018-04-24 上海市血液中心 一种血小板跨膜电位检测方法
US10448631B2 (en) 2015-09-22 2019-10-22 East Carolina University Cryopreservation using sucralose
CN111295094A (zh) 2017-10-09 2020-06-16 泰尔茂比司特生物技术有限公司 冻干容器及使用冻干容器的方法
WO2020113090A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
WO2020112963A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
JP2022525398A (ja) 2019-03-14 2022-05-13 テルモ ビーシーティー バイオテクノロジーズ，エルエルシー 凍結乾燥容器用充填治具、システム及び使用方法
WO2020227149A1 (en) 2019-05-03 2020-11-12 Cellphire, Inc. Materials and methods for producing blood products
CA3150936A1 (en) 2019-08-16 2021-02-25 Cellphire, Inc. Thrombosomes as an antiplatelet agent reversal agent
CA3150933A1 (en) * 2019-08-16 2021-02-25 Cellphire, Inc. Thrombosomes as an anticoagulant reversal agent
US11903971B2 (en) 2020-02-04 2024-02-20 Cellphire, Inc. Treatment of von Willebrand disease

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4251995A (en) 1979-04-25 1981-02-24 Hedbergska Stiftelsen Method of freezing human blood platelets in glycerol-glucose using a statically controlled cooling rate device
CH660634A5 (de) 1983-08-30 1987-05-15 Dimitrios Giannitsis Verfahren zur herstellung von natuerlichem immunoadsorbens.
WO1987000196A1 (en) 1985-07-09 1987-01-15 Quadrant Bioresources Limited Protection of proteins and the like
EP0208764A4 (de) 1985-01-11 1987-10-08 Univ California Konservierungsverfahren für liposome.
GB8604983D0 (en) * 1986-02-28 1986-04-09 Biocompatibles Ltd Protein preservation
GB8715238D0 (en) 1987-06-29 1987-08-05 Quadrant Bioresources Ltd Food process
GB8801338D0 (en) 1988-01-21 1988-02-17 Quadrant Bioresources Ltd Preservation of viruses
US5958670A (en) * 1988-05-18 1999-09-28 Cobe Laboratories, Inc. Method of freezing cells and cell-like materials
US5045446A (en) * 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
US5059518A (en) * 1988-10-20 1991-10-22 Coulter Corporation Stabilized lyophilized mammalian cells and method of making same
US5332578A (en) 1989-04-14 1994-07-26 Prp, Inc. Platelet membrane microparticles
US5428008A (en) 1989-04-14 1995-06-27 Prp, Inc. Therapeutic composition of micellar structures capable of promoting hemotasis
US5242792A (en) 1991-02-25 1993-09-07 The United States Of America As Represented By The Secretary Of The Navy Method for the preservation of red blood cells by lyophilization using glycerol or inositol with disaccharides
GB9114202D0 (en) * 1991-07-01 1991-08-21 Quadrant Holdings Cambridge Blood products
IL104470A0 (en) * 1992-01-21 1993-05-13 Cryopharm Corp Process for freezing cells and cell like materials and compositions prepared thereby
ES2194013T3 (es) * 1992-05-29 2003-11-16 Univ North Carolina Plaquetas de sangre humana de secado fijo farmaceuticamente aceptables.
JPH06154318A (ja) * 1992-11-25 1994-06-03 Fukuda Sangyo Kaihatsu Center Kk 点滴用輸液量測定装置
DE69534151T2 (de) 1994-02-22 2006-01-12 Nippon Telegraph And Telephone Corp. Gefriergetrocknete Blutzellen, Stammzellen und Plättchen und Verfahren zu deren Herstellung
JPH0920687A (ja) * 1995-07-03 1997-01-21 Nippon Telegr & Teleph Corp <Ntt> 凍結乾燥血液の戻し液
US5827741A (en) * 1996-11-19 1998-10-27 The Regents Of The University Of California Cryopreservation of human adult and fetal pancreatic cells and human platelets

Also Published As

Publication number Publication date
EP0967862B1 (de) 2003-01-15
JP2001511174A (ja) 2001-08-07
DK0967862T3 (da) 2003-05-12
AU732274B2 (en) 2001-04-12
DE69810755T2 (de) 2003-08-07
US6221575B1 (en) 2001-04-24
AU6220898A (en) 1998-08-26
CA2279376A1 (en) 1998-08-13
WO1998034478A1 (en) 1998-08-13
DE69810755D1 (de) 2003-02-20
CN1246778A (zh) 2000-03-08
EP0967862A1 (de) 2000-01-05
ZA981031B (en) 1998-08-11
ES2190063T3 (es) 2003-07-16

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