ATE214605T1 - Verwendung von eliprodil zur herstellung eines arzneimittels zur behandlung von ischämischen störungen der retina oder des sehnervs - Google Patents

Verwendung von eliprodil zur herstellung eines arzneimittels zur behandlung von ischämischen störungen der retina oder des sehnervs

Info

Publication number
ATE214605T1
ATE214605T1 AT96943986T AT96943986T ATE214605T1 AT E214605 T1 ATE214605 T1 AT E214605T1 AT 96943986 T AT96943986 T AT 96943986T AT 96943986 T AT96943986 T AT 96943986T AT E214605 T1 ATE214605 T1 AT E214605T1
Authority
AT
Austria
Prior art keywords
eliprodil
retina
optic nerve
manufacture
treatment
Prior art date
Application number
AT96943986T
Other languages
English (en)
Inventor
Michael A Kapin
Louis Desantis Jr
Bernard Scatton
Salomon Langer
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Application granted granted Critical
Publication of ATE214605T1 publication Critical patent/ATE214605T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT96943986T 1996-01-02 1996-12-17 Verwendung von eliprodil zur herstellung eines arzneimittels zur behandlung von ischämischen störungen der retina oder des sehnervs ATE214605T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58200396A 1996-01-02 1996-01-02
PCT/EP1996/005671 WO1997024123A1 (en) 1996-01-02 1996-12-17 Use of polyamine site antagonist for the manufacture of a medicament for the treatment of ischemic disorders of the eye

Publications (1)

Publication Number Publication Date
ATE214605T1 true ATE214605T1 (de) 2002-04-15

Family

ID=24327451

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96943986T ATE214605T1 (de) 1996-01-02 1996-12-17 Verwendung von eliprodil zur herstellung eines arzneimittels zur behandlung von ischämischen störungen der retina oder des sehnervs

Country Status (12)

Country Link
US (1) US6020352A (de)
EP (1) EP0871446B1 (de)
JP (1) JP2000507205A (de)
AT (1) ATE214605T1 (de)
AU (1) AU716670B2 (de)
CA (1) CA2241913A1 (de)
DE (1) DE69620027T2 (de)
DK (1) DK0871446T3 (de)
ES (1) ES2171233T3 (de)
HK (1) HK1016068A1 (de)
PT (1) PT871446E (de)
WO (1) WO1997024123A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9620350D0 (en) 1996-09-30 1996-11-13 Maudsley David J Cancer vaccine
US6509355B1 (en) * 1998-10-27 2003-01-21 Alcon Laboratories, Inc. Treatment of disorders of the outer retina
US20030212107A1 (en) * 2001-05-10 2003-11-13 Kapin Michael A. R-reliprodil for treating glaucoma
WO2005080394A1 (en) * 2004-02-24 2005-09-01 Bioaxone Therapeutique Inc. 4-substituted piperidine derivatives
GB2432526A (en) * 2005-11-24 2007-05-30 Arakis Ltd Use of ifenprodil for the treatment of ophthalmic diseases
US10106525B2 (en) 2015-01-26 2018-10-23 BioAxone BioSciences, Inc. Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
US10857157B2 (en) 2015-01-26 2020-12-08 BioAxone BioSciences, Inc. Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US10149856B2 (en) 2015-01-26 2018-12-11 BioAxone BioSciences, Inc. Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
US11198680B2 (en) 2016-12-21 2021-12-14 BioAxone BioSciences, Inc. Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
US10537567B2 (en) 2017-07-11 2020-01-21 BioAxone BioSciences, Inc. Kinase inhibitors for treatment of disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534580A1 (fr) * 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
US5922773A (en) * 1992-12-04 1999-07-13 The Children's Medical Center Corp. Glaucoma treatment

Also Published As

Publication number Publication date
EP0871446B1 (de) 2002-03-20
ES2171233T3 (es) 2002-09-01
JP2000507205A (ja) 2000-06-13
AU1373997A (en) 1997-07-28
DE69620027T2 (de) 2002-09-05
EP0871446A1 (de) 1998-10-21
DK0871446T3 (da) 2002-04-15
CA2241913A1 (en) 1997-07-10
AU716670B2 (en) 2000-03-02
HK1016068A1 (en) 1999-10-29
PT871446E (pt) 2002-08-30
DE69620027D1 (de) 2002-04-25
US6020352A (en) 2000-02-01
WO1997024123A1 (en) 1997-07-10

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee