ATE182884T1 - Mittel für behandlung der leber- gallenerkrankungen - Google Patents

Mittel für behandlung der leber- gallenerkrankungen

Info

Publication number
ATE182884T1
ATE182884T1 AT95303718T AT95303718T ATE182884T1 AT E182884 T1 ATE182884 T1 AT E182884T1 AT 95303718 T AT95303718 T AT 95303718T AT 95303718 T AT95303718 T AT 95303718T AT E182884 T1 ATE182884 T1 AT E182884T1
Authority
AT
Austria
Prior art keywords
literary
treatment
diseases
agents
methyl group
Prior art date
Application number
AT95303718T
Other languages
English (en)
Inventor
Ryuji Ueno
Original Assignee
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by R Tech Ueno Ltd filed Critical R Tech Ueno Ltd
Application granted granted Critical
Publication of ATE182884T1 publication Critical patent/ATE182884T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT95303718T 1994-06-03 1995-05-31 Mittel für behandlung der leber- gallenerkrankungen ATE182884T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12248794 1994-06-03

Publications (1)

Publication Number Publication Date
ATE182884T1 true ATE182884T1 (de) 1999-08-15

Family

ID=14837070

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95303718T ATE182884T1 (de) 1994-06-03 1995-05-31 Mittel für behandlung der leber- gallenerkrankungen

Country Status (14)

Country Link
US (1) US5739161A (de)
EP (1) EP0690049B1 (de)
KR (1) KR100260573B1 (de)
CN (1) CN1076605C (de)
AT (1) ATE182884T1 (de)
AU (1) AU690241B2 (de)
CA (1) CA2150287C (de)
DE (1) DE69511181T2 (de)
DK (1) DK0690049T3 (de)
ES (1) ES2137456T3 (de)
FI (1) FI952721A (de)
GR (1) GR3031066T3 (de)
NO (1) NO308993B1 (de)
NZ (1) NZ272234A (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29717252U1 (de) * 1997-09-26 1998-02-19 Dr. Falk Pharma GmbH, 79108 Freiburg Arzneimittelkit aus einem Budesonid-haltigen und einem Ursodesoxycholsäure-haltigen Arzneimittel zur Behandlung von cholestatischen Lebererkrankungen
TWI225398B (en) 1999-07-14 2004-12-21 R Tech Ueno Ltd Composition for treatment of external secretion disorders
DE60010913T2 (de) 1999-10-15 2005-06-09 Sucampo Ag Bizyklische Verbindungen, Zusammenstellung und Verfahren zu ihrer Stabilisierung
AU2001239551B8 (en) 2000-03-24 2005-11-24 Sucampo Ag Apoptosis inhibiting composition comprising a 15-keto-prostaglandin or derivative thereof
ATE433754T1 (de) * 2000-04-06 2009-07-15 Sucampo Ag Gallensäurefördernde zusammensetzung für lebertransplantation welche ein 15-keto prostaglandin enthält
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI302100B (en) 2001-05-02 2008-10-21 Sucampo Ag Composition for treating drug-induced constipation
NZ531503A (en) 2001-08-31 2006-01-27 Sucampo Ag Prostaglandin analogs as chloride channel opener
TWI331920B (en) * 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
US7732487B2 (en) * 2001-11-19 2010-06-08 Sucampo Ag Method for treating a disease or condition responsive to opening of C1C-2 channel
WO2005018646A1 (ja) 2003-08-21 2005-03-03 Sucampo Ag 眼科用組成物
ATE539756T1 (de) * 2002-10-23 2012-01-15 Sucampo Ag Prostaglandinsubstanzen für die behandlung von fettsucht
AU2003292556B2 (en) 2002-12-27 2009-09-10 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort
DE602004030245D1 (de) * 2003-07-03 2011-01-05 Sucampo Ag Pharmazeutische magensaftresistent überzogene zusammensetzung enthaltend prostaglandin-analoga als chloridkanalöffner
JP4690814B2 (ja) * 2004-08-02 2011-06-01 株式会社アールテック・ウエノ プロスタグランジン誘導体の製造法
TWI384988B (zh) * 2005-01-27 2013-02-11 Sucampo Ag 處理中樞神經系統失常用之組成物
EP2329825B1 (de) * 2005-03-04 2015-10-07 Sucampo AG Verfahren und Zusammensetzung zur Behandlung von peripheren Gefässkrankheiten
US20060281818A1 (en) 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
PL1871380T3 (pl) * 2005-04-12 2012-03-30 Sucampo Ag Zastosowanie kombinacji związku prostaglandyny i inhibitora pompy protonowej w leczeniu zaburzeń żołądkowo-jelitowych
AU2007208637B2 (en) 2006-01-24 2012-04-26 R-Tech Ueno, Ltd. Pharmaceutical composition comprising a bi-cyclic compound and method for stabilizing the bi-cyclic compound
DK1978944T3 (da) 2006-01-24 2012-11-05 Sucampo Ag Blød-gelatine-kapselformulering
JP4648340B2 (ja) * 2006-02-07 2011-03-09 株式会社アールテック・ウエノ １５−ケトプロスタグランジンｅ誘導体の製造法
WO2007091697A2 (en) * 2006-02-07 2007-08-16 R-Tech Ueno, Ltd. Method for preparing prostaglandin derivative
EP1988905B1 (de) * 2006-02-28 2014-06-04 Sucampo AG Verfahren und zusammensetzung zur behandlung von chronisch obstruktiver lungenerkrankung
CN103768070A (zh) * 2006-03-13 2014-05-07 株式会社·R-技术上野 水性组合物
US8871752B2 (en) * 2008-02-19 2014-10-28 Sucampo Ag Method for modulating stem cell growth
US8609729B2 (en) 2009-04-15 2013-12-17 Sucampo Ag Method for treating macular degeneration
US8569279B2 (en) * 2009-05-27 2013-10-29 Sucampo Ag Method for modulating claudin mediated functions
US20110034424A1 (en) * 2009-06-30 2011-02-10 Sucampo Ag Method for the long term nsaid use
US9084815B2 (en) * 2009-09-16 2015-07-21 Sucampo Ag Method for treating damage induced by an anti-tumor agent, treating mucositis and treating tumor
WO2012137987A1 (en) 2011-04-07 2012-10-11 Sucampo Ag Method for treating asthenopia
US20120270945A1 (en) * 2011-04-19 2012-10-25 Sucampo Ag Method for modulating cytokine activity
CN103764639B (zh) * 2011-07-01 2016-04-13 株式会社·R-技术上野 用于制备脂肪酸衍生物的方法
CN102875586A (zh) * 2011-07-11 2013-01-16 上海天伟生物制药有限公司 一种利马前列素关键中间体的制备方法
WO2013022079A1 (en) 2011-08-05 2013-02-14 Sucampo Ag Method for treating schizophrenia
CN103058907B (zh) * 2011-10-21 2016-05-11 武汉启瑞药业有限公司 鲁比前列酮或其中间体的制备方法
AR092821A1 (es) 2012-04-20 2015-05-06 Sucampo Ag Conjugado de derivado de acido graso-polimero
US20150057351A1 (en) 2013-08-22 2015-02-26 Sucampo Ag Method for treating neuropathic pain
WO2016203317A1 (en) 2015-06-19 2016-12-22 Sucampo Ag Pharmaceutical compositions comprising fatty acid derivative
US10428566B2 (en) * 2017-04-17 2019-10-01 James G. Arendts Flexible unitary sandwich-like panel overhead door

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4306078A (en) * 1979-12-03 1981-12-15 Hoffmann-La Roche Inc. 16-Substituted prostaglandins
US4374856A (en) 1980-09-10 1983-02-22 The Upjohn Company Liver cytoprotection using PGE's
JPS58164512A (ja) 1982-03-25 1983-09-29 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する肝臓疾患治療剤
JPS58203911A (ja) 1982-05-25 1983-11-28 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤
JPS62129218A (ja) 1985-12-02 1987-06-11 Teijin Ltd チアプロスタグランジン類を活性成分として含有する肝疾患治療剤
JPH0688966B2 (ja) 1987-01-28 1994-11-09 株式会社アールテック・ウエノ プロスタグランジンｅ類およびそれを含む抗潰瘍剤
US5166174A (en) * 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
CA1323364C (en) * 1987-01-28 1993-10-19 Ryuzo Ueno Prostaglandins e and anti ulcer agents containing same
GB2210556B (en) * 1987-10-02 1991-07-17 Ueno Seiyaku Oyo Kenkyujo Kk The use of 15-keto-16-halo-prostaglandins in cathartic compositions
JPH0681728B2 (ja) 1987-10-02 1994-10-19 株式会社上野製薬応用研究所 下 剤
JP2579193B2 (ja) * 1988-07-19 1997-02-05 小野薬品工業株式会社 １６，１６−ジフルオロ−１５−オキソ−１５−デオキシｐｇｅ誘導体
DD295522A5 (de) * 1989-07-26 1991-11-07 �����@������������������k�� 5-Alkyl-1,3,4-Thiadiazole, Verfahren zu ihrer Herstellung und Verwendung als Schädlingsbekämpfungsmittel
CA2027814C (en) * 1989-10-20 1996-07-30 Ryuji Ueno Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds

Also Published As

Publication number Publication date
KR960000230A (ko) 1996-01-25
US5739161A (en) 1998-04-14
CN1076605C (zh) 2001-12-26
NO952214L (no) 1995-12-04
DK0690049T3 (da) 2000-03-06
DE69511181T2 (de) 1999-12-02
NZ272234A (en) 1996-02-27
KR100260573B1 (ko) 2000-07-01
CA2150287C (en) 2004-08-10
FI952721A0 (fi) 1995-06-02
EP0690049A3 (de) 1997-03-26
EP0690049B1 (de) 1999-08-04
DE69511181D1 (de) 1999-09-09
CA2150287A1 (en) 1995-12-04
CN1126591A (zh) 1996-07-17
NO308993B1 (no) 2000-11-27
AU2041295A (en) 1995-12-14
GR3031066T3 (en) 1999-12-31
EP0690049A2 (de) 1996-01-03
ES2137456T3 (es) 1999-12-16
AU690241B2 (en) 1998-04-23
FI952721A (fi) 1995-12-04
NO952214D0 (no) 1995-06-02

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner