ATE178606T1 - Diclavulanat-salze mit diaminoether und verfahren zu deren herstellung - Google Patents

Diclavulanat-salze mit diaminoether und verfahren zu deren herstellung

Info

Publication number: ATE178606T1
Authority: AT; Austria
Prior art keywords: diaminoether; diclavulanate; salts; production; diclavulanate salts
Prior art date: 1994-12-24

Application number

AT95941809T

Other languages

English (en)

Inventor

George Leo Callewaert

Original Assignee

Spurcourt Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-12-24

Filing date

1995-12-22

Publication date

1999-04-15

1995-12-22 Application filed by Spurcourt Ltd filed Critical Spurcourt Ltd

1999-04-15 Application granted granted Critical

1999-04-15 Publication of ATE178606T1 publication Critical patent/ATE178606T1/de

Links

SBOJXQVPLKSXOG-UHFFFAOYSA-N o-amino-hydroxylamine Chemical compound NON SBOJXQVPLKSXOG-UHFFFAOYSA-N 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cephalosporin Compounds (AREA)

AT95941809T 1994-12-24 1995-12-22 Diclavulanat-salze mit diaminoether und verfahren zu deren herstellung ATE178606T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9426261.5A GB9426261D0 (en)	1994-12-24	1994-12-24	Clavulanic acid salts

Publications (1)

Publication Number	Publication Date
ATE178606T1 true ATE178606T1 (de)	1999-04-15

Family

ID=10766624

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95941809T ATE178606T1 (de)	1994-12-24	1995-12-22	Diclavulanat-salze mit diaminoether und verfahren zu deren herstellung

Country Status (40)

Country	Link
US (1)	US5786351A (de)
EP (1)	EP0799233B1 (de)
JP (1)	JPH10511386A (de)
KR (1)	KR100416946B1 (de)
CN (1)	CN1081640C (de)
AP (1)	AP670A (de)
AR (1)	AR004165A1 (de)
AT (1)	ATE178606T1 (de)
AU (1)	AU702968B2 (de)
BG (1)	BG62971B1 (de)
BR (1)	BR9510250A (de)
CA (1)	CA2208520C (de)
CZ (1)	CZ289287B6 (de)
DE (1)	DE69508962T2 (de)
DK (1)	DK0799233T3 (de)
EE (1)	EE9700139A (de)
ES (1)	ES2132756T3 (de)
FI (1)	FI972464A (de)
GB (1)	GB9426261D0 (de)
GE (1)	GEP20002212B (de)
GR (1)	GR3030629T3 (de)
HU (1)	HUT77090A (de)
IL (1)	IL116498A (de)
IS (1)	IS4501A (de)
MD (1)	MD1738F2 (de)
MY (1)	MY114213A (de)
NO (1)	NO313200B1 (de)
NZ (1)	NZ297857A (de)
OA (1)	OA10861A (de)
PL (1)	PL182364B1 (de)
RO (1)	RO118429B1 (de)
RU (1)	RU2152948C1 (de)
SE (1)	SE520665C2 (de)
SI (2)	SI9520145A (de)
SK (1)	SK282663B6 (de)
TJ (1)	TJ269B (de)
TR (1)	TR199501675A2 (de)
TW (1)	TW401409B (de)
WO (1)	WO1996020199A2 (de)
ZA (1)	ZA9510880B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SI9400107A (en)	1994-03-02	1995-10-31	Lek Tovarna Farmacevtskih	New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
GB9426261D0 (en) *	1994-12-24	1995-02-22	Spurcourt Ltd	Clavulanic acid salts
SI9500134B (sl)	1995-04-20	2004-04-30	Lek,	Postopek za pripravo čistih alkalijskih soli klavulanske kisline
PL333247A1 (en) *	1996-11-11	1999-11-22	Gist Brocades Bv	Method of manufacturing of salts and esters of clavulan acid
AT404728B (de) *	1996-11-27	1999-02-25	Biochemie Gmbh	Verfahren zur herstellung von clavulansäure-aminsalzen
WO2001087891A1 (en)	2000-05-13	2001-11-22	Smithkline Beecham P.L.C.	Process for the purification of a salt of clavulanic acid
CN102046800A (zh) *	2008-04-02	2011-05-04	帝斯曼知识产权资产管理有限公司	羧酸的二胺盐

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4144242A (en) *	1975-02-07	1979-03-13	Glaxo Laboratories Limited	Process for the purification of clavulanic acid
GB1578739A (en)	1976-07-23	1980-11-05	Beecham Group Ltd	Amine salts of clavulanic acid methods for their preparation and compositions containing them
US4255332A (en) *	1977-09-01	1981-03-10	Beecham Group Limited	Process for the preparation of potassium clavulanate from lithium clavulanate
DE3063683D1 (en) *	1979-08-24	1983-07-14	Beecham Group Plc	Amine salt of clavulanic acid, its preparation and use
US4454069A (en) *	1979-08-24	1984-06-12	Beecham Group Limited	Clavulanic acid salts and their preparation from the tertiary butyl amine salt
US5288861A (en)	1987-01-29	1994-02-22	Beecham Group Plc	Potassium clavulanate in rosette form
DK175709B1 (da)	1987-01-29	2005-01-31	Beecham Group Plc	Fremgangsmåde til fremstilling af kalium-clavulanat
ES2010143A6 (es) *	1989-03-01	1989-10-16	Pharma Mar S A Pharmar	Un nuevo procedimiento de obtencion del acido z(2r,5r)-3-(2-hiadroxietiliden)-7- oxo-4-oxa-1-azabiciclo(3,2,0) -heptano-2-carboxilico y de sales estares farmaceutiacamente aceptables del mismo,a partir de caldos de fermentacion de streptomyces, sp.
AT400033B (de) *	1992-03-10	1995-09-25	Biochemie Gmbh	Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben
AT399155B (de) *	1992-03-26	1995-03-27	Lek Tovarna Farmacevtskih	Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung
SI9300296B (sl) *	1992-06-11	1998-06-30	Smithkline Beecham P.L.C.	Postopek in intermedianti za pripravo klavulanske kisline
GB9305565D0 (en) *	1993-03-18	1993-05-05	Smithkline Beecham Plc	Novel compounds and processes
RO112113B1 (ro) *	1993-03-26	1997-05-30	Gist Brocades Nv	Saruri diaminice ale acidului clavulanic si procedeu pentru prepararea acestora
GB9426261D0 (en) *	1994-12-24	1995-02-22	Spurcourt Ltd	Clavulanic acid salts

1994
- 1994-12-24 GB GBGB9426261.5A patent/GB9426261D0/en active Pending
1995
- 1995-12-21 IL IL11649895A patent/IL116498A/xx not_active IP Right Cessation
- 1995-12-21 ZA ZA9510880A patent/ZA9510880B/xx unknown
- 1995-12-21 AR ARP950100702A patent/AR004165A1/es active IP Right Grant
- 1995-12-22 CA CA002208520A patent/CA2208520C/en not_active Expired - Fee Related
- 1995-12-22 CN CN95197032A patent/CN1081640C/zh not_active Expired - Fee Related
- 1995-12-22 AT AT95941809T patent/ATE178606T1/de not_active IP Right Cessation
- 1995-12-22 TJ TJ97000473A patent/TJ269B/xx unknown
- 1995-12-22 ES ES95941809T patent/ES2132756T3/es not_active Expired - Lifetime
- 1995-12-22 DE DE69508962T patent/DE69508962T2/de not_active Expired - Fee Related
- 1995-12-22 RO RO97-01119A patent/RO118429B1/ro unknown
- 1995-12-22 SK SK776-97A patent/SK282663B6/sk unknown
- 1995-12-22 AP APAP/P/1997/001013A patent/AP670A/en active
- 1995-12-22 EE EE9700139A patent/EE9700139A/xx unknown
- 1995-12-22 NZ NZ297857A patent/NZ297857A/en unknown
- 1995-12-22 HU HU9701685A patent/HUT77090A/hu not_active Application Discontinuation
- 1995-12-22 MD MD97-0230A patent/MD1738F2/ro unknown
- 1995-12-22 BR BR9510250A patent/BR9510250A/pt not_active IP Right Cessation
- 1995-12-22 SI SI9520145A patent/SI9520145A/sl unknown
- 1995-12-22 US US08/737,891 patent/US5786351A/en not_active Expired - Fee Related
- 1995-12-22 WO PCT/GB1995/003039 patent/WO1996020199A2/en active IP Right Grant
- 1995-12-22 TR TR95/01675A patent/TR199501675A2/xx unknown
- 1995-12-22 GE GEAP19953795A patent/GEP20002212B/en unknown
- 1995-12-22 JP JP8520309A patent/JPH10511386A/ja active Pending
- 1995-12-22 DK DK95941809T patent/DK0799233T3/da active
- 1995-12-22 AU AU43110/96A patent/AU702968B2/en not_active Ceased
- 1995-12-22 PL PL95321092A patent/PL182364B1/pl not_active IP Right Cessation
- 1995-12-22 EP EP95941809A patent/EP0799233B1/de not_active Expired - Lifetime
- 1995-12-22 CZ CZ19971920A patent/CZ289287B6/cs not_active IP Right Cessation
- 1995-12-22 RU RU97112159/04A patent/RU2152948C1/ru not_active IP Right Cessation
- 1995-12-22 SI SI9530245T patent/SI0799233T1/xx unknown
- 1995-12-22 KR KR1019970704332A patent/KR100416946B1/ko not_active IP Right Cessation
- 1995-12-23 MY MYPI95004076A patent/MY114213A/en unknown
1996
- 1996-01-06 TW TW085100132A patent/TW401409B/zh not_active IP Right Cessation
1997
- 1997-06-09 IS IS4501A patent/IS4501A/is unknown
- 1997-06-10 FI FI972464A patent/FI972464A/fi unknown
- 1997-06-17 SE SE9702306A patent/SE520665C2/sv not_active IP Right Cessation
- 1997-06-23 NO NO19972946A patent/NO313200B1/no not_active IP Right Cessation
- 1997-06-24 OA OA70038A patent/OA10861A/en unknown
- 1997-06-25 BG BG101671A patent/BG62971B1/bg unknown
1999
- 1999-06-30 GR GR990401715T patent/GR3030629T3/el unknown

Also Published As

Publication number	Publication date
RU2152948C1 (ru)	2000-07-20
IL116498A (en)	2000-07-26
ES2132756T3 (es)	1999-08-16
AR004165A1 (es)	1998-11-04
HUT77090A (hu)	1998-03-02
SE9702306D0 (sv)	1997-06-17
AP670A (en)	1998-09-04
OA10861A (en)	2003-02-17
BG62971B1 (bg)	2000-12-29
IL116498A0 (en)	1996-03-31
AU702968B2 (en)	1999-03-11
PL182364B1 (pl)	2001-12-31
CN1171111A (zh)	1998-01-21
NO313200B1 (no)	2002-08-26
SI0799233T1 (en)	1999-08-31
US5786351A (en)	1998-07-28
TW401409B (en)	2000-08-11
CZ289287B6 (cs)	2001-12-12
AP9701013A0 (en)	1997-07-31
NO972946L (no)	1997-06-23
WO1996020199A2 (en)	1996-07-04
EP0799233A2 (de)	1997-10-08
EP0799233B1 (de)	1999-04-07
CZ192097A3 (cs)	1998-08-12
SE9702306L (sv)	1997-08-25
SE520665C2 (sv)	2003-08-05
JPH10511386A (ja)	1998-11-04
BR9510250A (pt)	1997-11-04
NO972946D0 (no)	1997-06-23
MY114213A (en)	2002-08-30
SI9520145A (sl)	1998-02-28
DE69508962T2 (de)	1999-08-12
DK0799233T3 (da)	1999-10-18
RO118429B1 (ro)	2003-05-30
TJ269B (en)	2000-08-07
CA2208520C (en)	2003-10-07
SK282663B6 (sk)	2002-11-06
NZ297857A (en)	1997-11-24
CA2208520A1 (en)	1996-07-04
FI972464A (fi)	1997-08-21
GR3030629T3 (en)	1999-10-29
AU4311096A (en)	1996-07-19
DE69508962D1 (de)	1999-05-12
SK77697A3 (en)	1998-01-14
GB9426261D0 (en)	1995-02-22
FI972464A0 (fi)	1997-06-10
EE9700139A (et)	1997-12-15
KR100416946B1 (ko)	2004-05-10
MD970230A (en)	1999-05-31
WO1996020199A3 (en)	1996-09-12
MD1738F2 (ro)	2001-09-30
ZA9510880B (en)	1996-08-07
CN1081640C (zh)	2002-03-27
PL321092A1 (en)	1997-11-24
IS4501A (is)	1997-06-09
BG101671A (en)	1998-09-30
TR199501675A2 (tr)	1997-07-21
MX9704693A (es)	1998-06-30
GEP20002212B (en)	2000-08-25

Legal Events

Date	Code	Title	Description
1999-11-15	UEP	Publication of translation of european patent specification
2003-09-15	REN	Ceased due to non-payment of the annual fee

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