ATE14728T1 - Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika. - Google Patents

Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika.

Info

Publication number: ATE14728T1
Authority: AT; Austria
Prior art keywords: beta; lactam antibiotics; manufacture; thiazole derivatives; association
Prior art date: 1981-11-13

Application number

AT82306044T

Other languages

English (en)

Inventor

Alastair Couper Brodie

Brian Edgar Looker

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-11-13

Filing date

1982-11-12

Publication date

1985-08-15

1982-11-12 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1985-08-15 Application granted granted Critical

1985-08-15 Publication of ATE14728T1 publication Critical patent/ATE14728T1/de

Links

239000003782 beta lactam antibiotic agent Substances 0.000 title abstract 2
239000002132 β-lactam antibiotic Substances 0.000 title abstract 2
229940124586 β-lactam antibiotics Drugs 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
150000007979 thiazole derivatives Chemical class 0.000 title 1
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
WZPBZJONDBGPKJ-VEHQQRBSSA-N aztreonam Chemical compound O=C1N(S([O-])(=O)=O)[C@@H](C)[C@@H]1NC(=O)C(=N/OC(C)(C)C(O)=O)\C1=CSC([NH3+])=N1 WZPBZJONDBGPKJ-VEHQQRBSSA-N 0.000 abstract 1
229960003644 aztreonam Drugs 0.000 abstract 1
ORFOPKXBNMVMKC-DWVKKRMSSA-N ceftazidime Chemical compound S([C@@H]1[C@@H](C(N1C=1C([O-])=O)=O)NC(=O)\C(=N/OC(C)(C)C(O)=O)C=2N=C(N)SC=2)CC=1C[N+]1=CC=CC=C1 ORFOPKXBNMVMKC-DWVKKRMSSA-N 0.000 abstract 1
229960000484 ceftazidime Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004494 ethyl ester group Chemical group 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)

AT82306044T 1981-11-13 1982-11-12 Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika. ATE14728T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8134358		1981-11-13
EP82306044A EP0088183B1 (de)	1981-11-13	1982-11-12	Thiazol-Derivate und ihre Verwendung bei der Herstellung von beta-Lactam-Antibiotika

Publications (1)

Publication Number	Publication Date
ATE14728T1 true ATE14728T1 (de)	1985-08-15

Family

ID=10525888

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT82306044T ATE14728T1 (de)	1981-11-13	1982-11-12	Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika.

Country Status (5)

Country	Link
US (4)	US4497956A (de)
EP (1)	EP0088183B1 (de)
JP (1)	JPS58109477A (de)
AT (1)	ATE14728T1 (de)
DE (1)	DE3265277D1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE14728T1 (de) *	1981-11-13	1985-08-15	Glaxo Group Ltd	Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika.
EP0115770B2 (de) *	1983-01-07	1996-06-19	Takeda Chemical Industries, Ltd.	Thiazolderivate
US5182383A (en) *	1986-09-10	1993-01-26	Biochemie Gesellschaft M.B.H.	Stable, crystalline form of a cephalosporin intermediate product
IN189047B (de) *	1998-06-01	2002-12-14	Ranbaxy Lab Ltd
US7363759B2 (en) *	2002-10-15	2008-04-29	Kanzaki Kokyukoki Mfg. Co., Ltd.	Hydraulic transaxle apparatus for a four-wheel-drive vehicle and four-wheel-drive vehicle using the apparatus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4166115A (en) *	1976-04-12	1979-08-28	Fujisawa Pharmaceutical Co., Ltd.	Syn 7-oxoimino substituted derivatives of cephalosporanic acid
PH17188A (en) *	1977-03-14	1984-06-14	Fujisawa Pharmaceutical Co	New cephem and cepham compounds and their pharmaceutical compositions and method of use
SE439312B (sv) *	1977-03-25	1985-06-10	Roussel Uclaf	Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
AR229883A1 (es) *	1978-05-26	1983-12-30	Glaxo Group Ltd	Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
ATE14728T1 (de) *	1981-11-13	1985-08-15	Glaxo Group Ltd	Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika.

1982
- 1982-11-12 AT AT82306044T patent/ATE14728T1/de not_active IP Right Cessation
- 1982-11-12 JP JP57197860A patent/JPS58109477A/ja active Granted
- 1982-11-12 US US06/441,250 patent/US4497956A/en not_active Expired - Lifetime
- 1982-11-12 US US06/441,247 patent/US4493933A/en not_active Expired - Lifetime
- 1982-11-12 DE DE8282306044T patent/DE3265277D1/de not_active Expired
- 1982-11-12 EP EP82306044A patent/EP0088183B1/de not_active Expired
1984
- 1984-10-30 US US06/666,544 patent/US4665167A/en not_active Expired - Lifetime
- 1984-10-30 US US06/666,546 patent/US4667029A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US4665167A (en)	1987-05-12
JPS58109477A (ja)	1983-06-29
US4497956A (en)	1985-02-05
EP0088183B1 (de)	1985-08-07
EP0088183A1 (de)	1983-09-14
US4667029A (en)	1987-05-19
US4493933A (en)	1985-01-15
JPH0354662B2 (de)	1991-08-20
DE3265277D1 (en)	1985-09-12

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Legal Events

Date	Code	Title	Description
1985-11-15	UEP	Publication of translation of european patent specification
2003-02-15	EELA	Cancelled due to lapse of time