ATE135721T1 - Verfahren zur herstellung vernetzter polyamine - Google Patents

Verfahren zur herstellung vernetzter polyamine

Info

Publication number
ATE135721T1
ATE135721T1 AT91915184T AT91915184T ATE135721T1 AT E135721 T1 ATE135721 T1 AT E135721T1 AT 91915184 T AT91915184 T AT 91915184T AT 91915184 T AT91915184 T AT 91915184T AT E135721 T1 ATE135721 T1 AT E135721T1
Authority
AT
Austria
Prior art keywords
producing cross
linked polyamine
linked
cross
polyamines
Prior art date
Application number
AT91915184T
Other languages
English (en)
Inventor
Samuel Joseph Tremont
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Application granted granted Critical
Publication of ATE135721T1 publication Critical patent/ATE135721T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • C08G73/0206Polyalkylene(poly)amines
    • C08G73/0213Preparatory process
    • C08G73/0226Quaternisation of polyalkylene(poly)amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02Polyamines
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S525/00Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S525/923Aminoplast having terminal ethylenic unsaturation
AT91915184T 1990-07-26 1991-07-22 Verfahren zur herstellung vernetzter polyamine ATE135721T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55804190A 1990-07-26 1990-07-26

Publications (1)

Publication Number Publication Date
ATE135721T1 true ATE135721T1 (de) 1996-04-15

Family

ID=24227945

Family Applications (2)

Application Number Title Priority Date Filing Date
AT91913230T ATE104154T1 (de) 1990-07-26 1991-07-22 Arzneimittel freisetzendes polymeres system.
AT91915184T ATE135721T1 (de) 1990-07-26 1991-07-22 Verfahren zur herstellung vernetzter polyamine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT91913230T ATE104154T1 (de) 1990-07-26 1991-07-22 Arzneimittel freisetzendes polymeres system.

Country Status (15)

Country Link
US (5) US5827925A (de)
EP (2) EP0540580B1 (de)
JP (2) JP2611073B2 (de)
AT (2) ATE104154T1 (de)
AU (2) AU8285991A (de)
CA (2) CA2085366C (de)
DE (2) DE69101710T2 (de)
DK (2) DK0540670T3 (de)
ES (2) ES2053333T3 (de)
GR (1) GR3019804T3 (de)
IE (1) IE912630A1 (de)
NZ (1) NZ239133A (de)
PT (1) PT98442B (de)
WO (2) WO1992001477A1 (de)
ZA (1) ZA915892B (de)

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US5559193A (en) * 1993-12-20 1996-09-24 Monsanto Company Controlled functional density polyamines and method for preparation thereof
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US6030959A (en) * 1997-04-04 2000-02-29 Monsanto Company Gastro-specific prodrugs
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US20130203675A1 (en) 2010-09-16 2013-08-08 Joseph M. DeSimone Asymmetric biofunctional silyl monomers and particles thereof as prodrugs and delivery vehicles for pharmaceutical, chemical and biological agents
WO2013009701A2 (en) 2011-07-08 2013-01-17 The University Of North Carolina At Chapel Hill Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders
EP3065713B1 (de) 2013-11-06 2024-03-06 The University of Chicago Nanoskalige träger zur freisetzung oder gemeinsamen abgabe von chemotherapeutika, nukleinsäuren und photosensibilisatoren
US10806694B2 (en) 2014-10-14 2020-10-20 The University Of Chicago Nanoparticles for photodynamic therapy, X-ray induced photodynamic therapy, radiotherapy, radiodynamic therapy, chemotherapy, immunotherapy, and any combination thereof
CN110731961A (zh) 2014-10-14 2020-01-31 芝加哥大学 金属有机框架、药物制剂及其在制备药物中的用途
CN109310702A (zh) 2016-05-20 2019-02-05 芝加哥大学 用于化学疗法、靶向疗法、光动力疗法、免疫疗法和它们的任何组合的纳米颗粒
WO2018118902A1 (en) 2016-12-19 2018-06-28 The Regents Of The University Of California Dual-enzyme responsive peptides
US11541125B2 (en) 2016-12-19 2023-01-03 The Regents Of The University Of California Noncrushable pill formulations
JP7216006B2 (ja) 2017-03-22 2023-01-31 ジェネンテック, インコーポレイテッド ヒドロゲル架橋ヒアルロン酸プロドラッグ組成物及び方法
JP7364552B2 (ja) 2017-08-02 2023-10-18 ザ ユニバーシティ オブ シカゴ X線誘起光線力学療法、放射線療法、放射線力学療法、化学療法、免疫療法、及びそれらの任意の組み合わせのための、ナノスケール金属有機層及び金属有機ナノプレート
US10994261B2 (en) 2018-01-18 2021-05-04 Research Triangle Institute Polyamine phosphorus dendrimer materials for carbon dioxide capture

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Also Published As

Publication number Publication date
ES2084825T3 (es) 1996-05-16
US5474767A (en) 1995-12-12
NZ239133A (en) 1993-10-26
CA2085366C (en) 2001-06-12
ES2053333T3 (es) 1994-07-16
WO1992001477A1 (en) 1992-02-06
CA2085366A1 (en) 1992-01-27
WO1992001730A1 (en) 1992-02-06
AU8285991A (en) 1992-02-18
JPH06502391A (ja) 1994-03-17
GR3019804T3 (en) 1996-07-31
JPH05508680A (ja) 1993-12-02
EP0540580B1 (de) 1994-04-13
US5676939A (en) 1997-10-14
DK0540580T3 (da) 1994-05-16
CA2086527A1 (en) 1992-01-27
PT98442A (pt) 1992-06-30
US5693319A (en) 1997-12-02
IE912630A1 (en) 1992-01-29
EP0540580A1 (de) 1993-05-12
AU8418891A (en) 1992-02-18
DK0540670T3 (da) 1996-04-29
ZA915892B (en) 1992-09-30
DE69118188D1 (de) 1996-04-25
EP0540670B1 (de) 1996-03-20
DE69118188T2 (de) 1996-10-31
DE69101710D1 (de) 1994-05-19
DE69101710T2 (de) 1994-08-18
ATE104154T1 (de) 1994-04-15
JP2611073B2 (ja) 1997-05-21
US5795567A (en) 1998-08-18
PT98442B (pt) 1999-01-29
US5827925A (en) 1998-10-27
EP0540670A1 (de) 1993-05-12

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