ATE119397T1 - Verwendung von nitrophenylen oder antinitrophenylen -antikörpern zur veränderung der wechselwirkung zwischen empfindlichen wirtszellen und einem erreger. - Google Patents

Verwendung von nitrophenylen oder antinitrophenylen -antikörpern zur veränderung der wechselwirkung zwischen empfindlichen wirtszellen und einem erreger.

Info

Publication number
ATE119397T1
ATE119397T1 AT88402733T AT88402733T ATE119397T1 AT E119397 T1 ATE119397 T1 AT E119397T1 AT 88402733 T AT88402733 T AT 88402733T AT 88402733 T AT88402733 T AT 88402733T AT E119397 T1 ATE119397 T1 AT E119397T1
Authority
AT
Austria
Prior art keywords
antibodies
interaction
pathogue
antinitrophenylene
nitrophenylene
Prior art date
Application number
AT88402733T
Other languages
English (en)
Inventor
Eustrate-Stratis Avrameas
Panayota Matsiota-Bernard
Therese Ternynck
Marie-Francoise Saron
Jean-Claude Guillon
Luc Montagnier
Denise Guetard
Veronique Favier
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Institut filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE119397T1 publication Critical patent/ATE119397T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/04Nitro compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • A61K31/06Phenols the aromatic ring being substituted by nitro groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542Carboxylic acids, e.g. a fatty acid or an amino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT88402733T 1987-10-30 1988-10-28 Verwendung von nitrophenylen oder antinitrophenylen -antikörpern zur veränderung der wechselwirkung zwischen empfindlichen wirtszellen und einem erreger. ATE119397T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8715126A FR2622444B1 (fr) 1987-10-30 1987-10-30 Application de dinitro-trinitrophenyle et de ses derives ou d'anticorps anti-nitrophenyles a la modification de l'interaction entre des cellules sensibles d'un hote et un agent pathogene

Publications (1)

Publication Number Publication Date
ATE119397T1 true ATE119397T1 (de) 1995-03-15

Family

ID=9356378

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88402733T ATE119397T1 (de) 1987-10-30 1988-10-28 Verwendung von nitrophenylen oder antinitrophenylen -antikörpern zur veränderung der wechselwirkung zwischen empfindlichen wirtszellen und einem erreger.

Country Status (8)

Country Link
EP (1) EP0316212B1 (de)
JP (1) JPH02501932A (de)
AT (1) ATE119397T1 (de)
DE (1) DE3853261D1 (de)
DK (1) DK328289A (de)
FR (1) FR2622444B1 (de)
PT (1) PT88889B (de)
WO (1) WO1989003690A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015326A1 (en) * 1991-02-27 1992-09-17 The Regents Of The University Of California Targeting complex mediated immunogenicity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2963410D1 (en) * 1978-08-10 1982-09-16 Schering Ag Process for obtaining murine immunglobulin-e antibodies, hybrid cell lines used in the process and the process for preparing them, application of the immunglobulin-e antibodies so obtained
US4474893A (en) * 1981-07-01 1984-10-02 The University of Texas System Cancer Center Recombinant monoclonal antibodies
US4673691A (en) * 1984-11-05 1987-06-16 Nicholas Bachynsky Human weight loss inducing method

Also Published As

Publication number Publication date
FR2622444A1 (fr) 1989-05-05
DK328289D0 (da) 1989-06-30
WO1989003690A1 (fr) 1989-05-05
PT88889A (pt) 1989-07-31
JPH02501932A (ja) 1990-06-28
EP0316212B1 (de) 1995-03-08
DK328289A (da) 1989-06-30
PT88889B (pt) 1993-05-31
DE3853261D1 (de) 1995-04-13
EP0316212A1 (de) 1989-05-17
FR2622444B1 (fr) 1990-08-03

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