ATE117691T1 - Verfahren zur herstellung von 3-unsubstituierten cephalosporinen und 1- carba(dethia)cephalosporinen. - Google Patents

Verfahren zur herstellung von 3-unsubstituierten cephalosporinen und 1- carba(dethia)cephalosporinen.

Info

Publication number
ATE117691T1
ATE117691T1 AT89302777T AT89302777T ATE117691T1 AT E117691 T1 ATE117691 T1 AT E117691T1 AT 89302777 T AT89302777 T AT 89302777T AT 89302777 T AT89302777 T AT 89302777T AT E117691 T1 ATE117691 T1 AT E117691T1
Authority
AT
Austria
Prior art keywords
cephalosporins
dethia
carba
beta
cephem
Prior art date
Application number
AT89302777T
Other languages
English (en)
Inventor
Gwendolyn Kay Cook
Iii John Hampton Mcdonald
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE117691T1 publication Critical patent/ATE117691T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02—Preparation
    • C07D463/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT89302777T 1988-03-23 1989-03-21 Verfahren zur herstellung von 3-unsubstituierten cephalosporinen und 1- carba(dethia)cephalosporinen. ATE117691T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/172,099 US4820832A (en) 1988-03-23 1988-03-23 Process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia)cephalosporins

Publications (1)

Publication Number Publication Date
ATE117691T1 true ATE117691T1 (de) 1995-02-15

Family

ID=22626360

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89302777T ATE117691T1 (de) 1988-03-23 1989-03-21 Verfahren zur herstellung von 3-unsubstituierten cephalosporinen und 1- carba(dethia)cephalosporinen.

Country Status (11)

Country Link
US (1) US4820832A (de)
EP (1) EP0334592B1 (de)
JP (1) JPH024789A (de)
KR (1) KR890014556A (de)
AT (1) ATE117691T1 (de)
DE (1) DE68920763T2 (de)
ES (1) ES2066844T3 (de)
GR (1) GR3015471T3 (de)
HU (1) HU207328B (de)
IE (1) IE65166B1 (de)
IL (1) IL89700A0 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128336A (en) * 1988-03-23 1992-07-07 Eli Lilly And Company 3-(substituted)-1-carba(dethia)-3-cephems
US5245027A (en) * 1989-11-21 1993-09-14 Bristol-Myers Squibb Company 3-fluorosulfonyloxyceph-3-em compounds
JP2541466Y2 (ja) * 1990-11-30 1997-07-16 三洋電機株式会社 時計機能付電気機器

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936914B2 (ja) * 1978-06-24 1984-09-06 協和醗酵工業株式会社 セフアロスポリン類縁体
US4436903A (en) * 1980-12-22 1984-03-13 Ciba-Geigy Corporation Process for the production of 7 β-substituted-3-unsubstituted-3-cephem-4-carboxylic acid compounds
AU575854B2 (en) * 1983-10-04 1988-08-11 Shionogi & Co., Ltd. 7beta-(carboxyalkenamido) cephalosporins
US4647658A (en) * 1984-06-08 1987-03-03 Shionogi & Co., Ltd. Process for preparing aminohydroxycephamcarboxylates
US4665171A (en) * 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics
US4673737A (en) * 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof

Also Published As

Publication number Publication date
GR3015471T3 (en) 1995-06-30
IE65166B1 (en) 1995-10-04
HU207328B (en) 1993-03-29
ES2066844T3 (es) 1995-03-16
EP0334592B1 (de) 1995-01-25
KR890014556A (ko) 1989-10-24
DE68920763D1 (de) 1995-03-09
JPH024789A (ja) 1990-01-09
EP0334592A3 (de) 1991-04-24
US4820832A (en) 1989-04-11
IE890905L (en) 1989-09-23
EP0334592A2 (de) 1989-09-27
HUT50344A (en) 1990-01-29
DE68920763T2 (de) 1995-06-08
IL89700A0 (en) 1989-09-28

Similar Documents

Publication Publication Date Title
DE69328668D1 (de) Einstufiges verfahren zur herstellung von alkenylbernsteinsäureanhydriden
DE69301571D1 (de) Verfahren zur Herstellung von Clavulansäure
DE69432553T2 (de) Verfahren zur Herstellung von Polyestern
ATE92436T1 (de) Verfahren zur erzeugung von chlordioxyd.
DE69726395D1 (de) Verfahren zur Herstellung von Carbonsäuren
DE69022650D1 (de) Katalytisches Verfahren zur Herstellung von Carbonsäure und Carbonsäure-Estern.
DE3871175D1 (de) Verfahren zur herstellung von perovskit und abo3-typ-oxyden.
DE3874375D1 (de) Verfahren zur herstellung von carbonsaeure-amiden oder -estern.
DE69020172D1 (de) Verfahren zur Herstellung von epsilon-Caprolactam.
ATE117691T1 (de) Verfahren zur herstellung von 3-unsubstituierten cephalosporinen und 1- carba(dethia)cephalosporinen.
DE3851588D1 (de) Verfahren zur Herstellung von Chinoloncarbonsäuren.
DE59100877D1 (de) Verfahren zur Herstellung von Carbonsäurechloriden.
DE69026608D1 (de) Verfahren zur Herstellung von synthetischem Rutil aus titanhaltiger Schlacke, die Magnesium enthält
DE3863378D1 (de) Verfahren zur herstellung von koks hoher qualitaet.
DE3774954D1 (de) Verfahren zur herstellung von penemen.
DE68923312D1 (de) Verfahren zur Herstellung von Caprolactam mit hoher Reinheit.
DE58907409D1 (de) Verfahren zur Herstellung von Caprolactam.
ATE202780T1 (de) 3-(substituierte)-1-carba(dethia)-3- cephemverbindungen und cephalosporine und ein verfahren zu ihrer herstellung
DE69225560D1 (de) Verfahren zur Herstellung von Lactonen
DE3688302D1 (de) Verfahren zur herstellung von 7-aca-derivaten.
DE58905010D1 (de) Verfahren zur herstellung von 5-chlor-3-chlorsulfonyl-2-thiophencarbonsaeureestern.
DE68922701D1 (de) Verfahren zur Herstellung von Polyesterfilamenten.
DE3872007D1 (de) Verfahren zur herstellung von carbonsaeuren.
ATE113952T1 (de) Verfahren zur herstellung von 3- exomethylencephamderivaten.
DE59104041D1 (de) Verfahren zur Herstellung von Carbonsäurechloriden.